Microbiologia/Virologia

<p>Ivermectin B1a aglycone, from ivermectin's disaccharide hydrolysis, inhibits nematode larvae growth without paralysis.</p>

<p>Quellenin, an anti-saprolegnia compound, is isolated from the deep-sea fungus Aspergillus sp. YK-76 [1].</p>

<p>17-Hydroxyneomatrine, a compound derived from Sophora flavescens, exhibits multifaceted biological activities, including the inhibition of human cervical</p>

<p>Nannochelin B is a siderophore isolated from Nannocystis exedens.</p>

<p>Razupenem (SMP-601, PTZ601), a broad-spectrum injectable carbapenem, counters antibiotic-resistant bacteria.</p>

<p>Compound 1h (Antibacterial agent 108) is a potent antibacterial agent, demonstrating a minimum inhibitory concentration (MIC) of 3 μM against both MRSA and</p>

<p>Josamycin propionate is a macrolide antibiotic.</p>

<p>Compound 6 (Antibacterial agent 161, trifluoromethanesulfonate) exhibits antibacterial properties and demonstrates significant antiproliferative effects against</p>

<p>Averufin is a natural product that can be used as a reference standard. The CAS number of Averufin is 14016-29-6.</p>

<p>(2S,5S)-Censavudine, a potent HIV inhibitor and nucleoside reverse transcriptase blocker.</p>

<p>Phosphomannose isomerase, the initial enzyme in GDP-Man biosynthesis, catalytically facilitates the interconversion of fructose-6-phosphate (Fru6P) and mannose-</p>

<p>Peritassine A, an alkaloid derived from Tripterygium wilfordii Hook. f., exhibits anti-HIV properties.</p>

<p>Antifungal agent 82 (compound G34) demonstrates outstanding in vitro antifungal efficacy against Valsa mali, exhibiting an EC50 value of 0.57 μg/mL, and has</p>

<p>Harzianopyridone is an atpenin-like compound that functions as an inhibitor of mammalian and nematode mitochondrial complex II, also known as succinate:ubiquinone oxidoreductase (SQR), demonstrating IC50 values of 0.017, 0.2, and 2 μM against bovine, rat, and nematode complex II, respectively. Additionally, it inhibits nematode quinol-fumarate reductase (QFR) with an IC50 value of 0.36 μM. Significantly selective for complex II over complexes I and III in rats and cattle, as well as complex I in nematodes, with IC50 values exceeding 100 μM, it exhibits notable antibacterial and antifungal properties, with EC50 values of 35.9, 42.2, 60.4, and 50.2 μg/ml against R. solani, S. rolfsii, M. phaseolina, and F. oxysporum, respectively.</p>

<p>HCVP-IN-1 (compound 1) is a hepatitis C viral polymerase (HCVP) inhibitor.</p>

<p>Agent 37 from patent WO2015063714A1 is a potent antimicrobial for bacterial infection research.</p>

<p>PEX5-PEX14 PPI-IN-1 (Compound 8) is a PEX14-PEX5 protein-protein interaction (PPI) inhibitor that disrupts the interaction between PEX5 and TbPEX14 with an</p>

<p>Parvodicin C2, a glycopeptide antibiotic derived from A. parvosata and part of the parvodicin complex, serves as a component of the A40926 antibiotic complex utilized as a precursor for synthesizing dalbavancin. It exhibits activity against methicillin-sensitive and methicillin-resistant strains of S. aureus, S. epidermidis, S. saprophyticus, S. hemolyticus, and E. faecalis.</p>

<p>XT-1, an antimicrobial peptide sourced from Xenopus tropicalis skin secretions, exhibits potent activity against S.</p>

<p>(+)-Epieudesmin is an antineoplastic agent with limited inhibitory effects on cancer cell lines and possesses the ability to hinder the growth of Gram-negative</p>