Microbiologia/Virologia
Os inibidores de microbiologia e virologia são compostos que têm como alvo microrganismos, incluindo bactérias, vírus e fungos, interrompendo seu crescimento, replicação ou sobrevivência. Esses inibidores são essenciais para estudar a patogênese microbiana, entender os mecanismos de resistência e desenvolver novas terapias antimicrobianas e antivirais. Os inibidores nessa categoria são usados para combater doenças infecciosas, explorar a ecologia microbiana e investigar as interações hospedeiro-patógeno. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para microbiologia e virologia para apoiar sua pesquisa em doenças infecciosas, microbiologia e virologia.
Subcategorias de "Microbiologia/Virologia"
- Antibacteriano(2.957 produtos)
- Antibiótico(920 produtos)
- Antifecção(23 produtos)
- DHFR(33 produtos)
- Síntese de DNA/RNA(708 produtos)
- HBV(176 produtos)
- HIV Protease(449 produtos)
- HSV(91 produtos)
- Integrase(2 produtos)
- Ribossomo(13 produtos)
Exibir 2 mais subcategorias
Foram encontrados 5842 produtos de "Microbiologia/Virologia"
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Antibacterial agent 174
CAS:<p>Compound 174 (Compound 5g), an antibacterial agent, exhibits potent anti-infective properties in vivo along with appreciable pharmacokinetic profiles. This highly active substance demonstrates favorable biofilm removal capabilities, low hemolysis, and acceptable mammalian cell toxicity [1].</p>Fórmula:C25H30FN2NaO5Cor e Forma:SolidPeso molecular:480.5SARS-CoV-2-IN-6
<p>SARS-CoV-2-IN-6 is an inhibitor of SARS-CoV-2 3CLpro with the IC 50 value of 73 nM.</p>Fórmula:C17H13ClN2O2Cor e Forma:SolidPeso molecular:312.75HIV-IN-3
<p>HIV-IN-3 (Compound 22a) is a potent inhibitor of HIV (IC50: 1.5 μM). HIV-IN-3 has potential for the study of HIV-related diseases.</p>Fórmula:C21H32ClN7O3Cor e Forma:SolidPeso molecular:465.98MBX-1162
CAS:<p>MBX-1162, a bis-indole compound, has demonstrated unique substrate specificity related to MepA and MepR in studies investigating its resistance mechanisms in Staphylococcus aureus. It has not shown cross-resistance with related compounds.</p>Fórmula:C30H28N6Cor e Forma:SolidPeso molecular:472.58Xanthosine-5'-Triphosphate trisodium
CAS:<p>Xanthosine-5'-Triphosphate (5'-XTP) trisodium is a nucleotide formed through the deamination of purine bases. It serves as a substrate for inosine triphosphate pyrophosphatase (ITPase).</p>Fórmula:C10H12N4Na3O15P3Cor e Forma:SolidPeso molecular:590.111ZIKV-IN-4
<p>ZIKV-IN-4 is a low cytotoxic, acid-stable anti-ZIKV agent with an EC50 value of 3.49 μM. ZIKV-IN-4 exhibited potent inhibition of ZIKV NS5 MTase.</p>Fórmula:C33H37NO4Cor e Forma:SolidPeso molecular:511.65DHX9-IN-9
CAS:<p>DHX9-IN-9 (509) acts as an inhibitor of the RNA helicase DHX9, demonstrating an EC50 of 0.0177 μM in DHX9 cellular target engagement, primarily utilized in cancer research [1].</p>Fórmula:C21H21ClFN5O3S2Cor e Forma:SolidPeso molecular:510LpxA-IN-1
CAS:<p>LpxA-IN-1, a novel UDP-N-acetylglucosamine acyltransferase (LpxA) inhibitor exhibiting potent activity (IC 50 2 nM), effectively targets Pseudomonas aeruginosa</p>Fórmula:C21H11D7F3N5O3Cor e Forma:SolidPeso molecular:452.44Antibacterial agent 169
CAS:<p>Antibacterial agent 169 (Compound 28), a pyrrolamide-type GyrB/ParE inhibitor, exhibits antibacterial properties by inhibiting Gyrase and Topo IV in Staphylococcus aureus. It has IC 50 values of 49 nmol/L and 1.513 μmol/L, respectively [1].</p>Fórmula:C19H25Cl2N5O3Cor e Forma:SolidPeso molecular:442.34WQ3810 TFA
<p>WQ3810 TFA is an orally available fluoroquinolone with antimicrobial activity against Mycobacterium tuberculosis and inhibits the DNA rotamase activity of</p>Fórmula:C24H23F6N5O5Pureza:99.52%Cor e Forma:SoildPeso molecular:575.46Desthiazolylmethyl ritonavir
CAS:<p>Desthiazolylmethyl ritonavir is an alkaline-catalyzed degradation product of the HIV protease inhibitor Ritonavir.</p>Fórmula:C33H43N5O4SCor e Forma:SolidPeso molecular:605.791PAV-104
CAS:<p>PAV-104 inhibits the replication of SARS-CoV-2 at a MOI of 0.01. It interacts with the SARS-CoV-2 nucleocapsid (N) and disrupts its oligomerization, thereby preventing particle assembly.</p>Fórmula:C29H35N5O6SCor e Forma:SolidPeso molecular:581.68MsbA-IN-4
<p>MsbA-IN-4 (Compound 32) is a highly selective and potent inhibitor of MsbA (IC50: 3 nM).MsbA-IN-4 inhibits Escherichia coli (MIC: 12 μM).</p>Fórmula:C23H18Cl2FN5OCor e Forma:SolidPeso molecular:470.33WRN inhibitor 11
CAS:<p>WRN inhibitor 11 (Example 17) is an orally effective inhibitor of WRN helicase, with an IC50 of 63 nM.</p>Fórmula:C34H35ClF3N9O5Cor e Forma:SolidPeso molecular:742.15SARS-CoV-2-IN-100
CAS:SARS-CoV-2-IN-100 (Compound 172) is a broad-spectrum antiviral agent against various SARS-CoV-2 variants. It works synergistically with Nirmatrelvir to reduce the risk of antiviral resistance.Fórmula:C29H23NO2Cor e Forma:SolidPeso molecular:417.50Metallo-β-lactamase-IN-16
CAS:<p>Metallo-β-lactamase-IN-16 (compound 18), a sulfone-containing metallo-β-lactamase inhibitor, exhibits antimicrobial activity. It effectively inhibits various metallo-β-lactamases, including NDM-1 (New Delhi metallo-β-lactamase-1), IMP-1 (imipenemase-1), VIM-1 (Verona Integron-encoded Metallo-β-lactamase), and VIM-2. The IC50 values for these enzymes are 0.16 nM, 0.23 nM, 0.31 nM, and 1.0 nM respectively.</p>Fórmula:C16H16N8O4S3Cor e Forma:SolidPeso molecular:480.54SARS-CoV-2-IN-102
CAS:<p>SARS-CoV-2-IN-102 (example 58) is an inhibitor of the SARS-CoV papain-like protease (SARS-CoVPLpro), demonstrating an IC50 of less than 100 nM.</p>Fórmula:C29H34F2N6O2Cor e Forma:SolidPeso molecular:536.62Antifungal agent 113
CAS:<p>Antifungalagent 113 (compound 9a) serves as an effective antifungal and antibacterial agent. It exhibits strong inhibitory activity against both S. aureus and methicillin-resistant S. aureus.</p>Fórmula:C23H20O5Cor e Forma:SolidPeso molecular:376.40HRSV/HMPV-IN-1
CAS:<p>HRSV/HMPV-IN-1 (compound 3) is an inhibitor targeting HRSV/HMPV, exhibiting EC50 values of < 0.2 μM against human RSV-A and < 0.5 μM for human MPV A2 TN/94-49. This compound is utilized in the study of bronchiolitis and pneumonia.</p>Fórmula:C34H31ClF2N4O5SCor e Forma:SolidPeso molecular:681.15MED6-189
CAS:<p>MED6-189, an analog of kalihinol, disrupts the apicoplast functions and vesicular transport in the malignant malaria parasite (P. falciparum, IC50 < 50 nM). The compound specifically targets the apicoplast, which is a non-photosynthetic plastid essential for isoprenoid synthesis, found in most apicomplexan parasites.</p>Fórmula:C17H26N2OCor e Forma:SolidPeso molecular:274.40
