Microbiologia/Virologia
Os inibidores de microbiologia e virologia são compostos que têm como alvo microrganismos, incluindo bactérias, vírus e fungos, interrompendo seu crescimento, replicação ou sobrevivência. Esses inibidores são essenciais para estudar a patogênese microbiana, entender os mecanismos de resistência e desenvolver novas terapias antimicrobianas e antivirais. Os inibidores nessa categoria são usados para combater doenças infecciosas, explorar a ecologia microbiana e investigar as interações hospedeiro-patógeno. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para microbiologia e virologia para apoiar sua pesquisa em doenças infecciosas, microbiologia e virologia.
Subcategorias de "Microbiologia/Virologia"
- Antibacteriano(3.153 produtos)
- Antibiótico(932 produtos)
- Antifecção(24 produtos)
- DHFR(34 produtos)
- Síntese de DNA/RNA(774 produtos)
- HBV(182 produtos)
- HIV Protease(477 produtos)
- HSV(94 produtos)
- Integrase(2 produtos)
- Ribossomo(13 produtos)
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Foram encontrados 6158 produtos de "Microbiologia/Virologia"
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MI-1851
CAS:<p>MI-1851 is a potent peptidomimetic inhibitor. MI-1851could prevent proteolytic processing of the S protein from SARSCoV-2 by endogenous furin in HEK293 cells.</p>Fórmula:C34H53N15O6Cor e Forma:SolidPeso molecular:767.88ZK-316
CAS:ZK-316 is a potent and broad-spectrum NNRTI inhibitor with an EC50 range of 0.99 to 75.1 nM. It is applicable for HIV research.Fórmula:C27H22D6N6O3S2Cor e Forma:SolidPeso molecular:554.72NBTIs-IN-5
CAS:NBTIs-IN-5 inhibits Mycobacterium abscessus DNA with IC50 1.5μM, halts growth at MIC90 0.4μM.Fórmula:C24H25F3N4O2Cor e Forma:SolidPeso molecular:458.48NITD-688
CAS:NITD-688 is a pan-serotype inhibitor targeting the dengue virus NS4B protein, effective through oral administration.Fórmula:C25H32N4O3S2Cor e Forma:SolidPeso molecular:500.68Antifungal agent 127
CAS:<p>Antifungalagent 127 (Compound 6c) is an antifungal agent with potent inhibitory activity against Botrytis cinerea and Rhizoctonia solani.</p>Fórmula:C13H12ClN3OCor e Forma:SolidPeso molecular:261.707XR8-89
CAS:XR8-89, a potent PLpro inhibitor (IC50=0.1μM), blocks SARS-CoV-2 replication; useful for research.Fórmula:C29H36N4O2SCor e Forma:SolidPeso molecular:504.69Antifungal agent 40
<p>Antifungal agent 40 blocks C. albicans CYP51 in pocket II, hindering lanosterol demethylase and biofilm growth.</p>Fórmula:C22H20Cl2N4SeCor e Forma:SolidPeso molecular:490.29BMS-818251
CAS:BMS-818251 is a potent small-molecule inhibitor that targets HIV-1 entry, with an EC50 value of 0.019 nM. It exhibits over 10 times greater efficacy on the cross-subtype panels of the 208-HIV-1 strain compared to BMS-626529. BMS-818251 enhances potency through interactions with gp120 residues in the conserved β20-β21 hairpin.Fórmula:C29H26N6O5SCor e Forma:SolidPeso molecular:570.619ZLM-66
<p>ZLM-66: Doravirine analog, HIV-1 NNRTI inhibitor, IC50: 41nM, EC50: HIV-1 13nM, cIAP1 0.32nM; useful in AIDS research.</p>Cor e Forma:SolidAntitubercular agent-15
Antitubercular agent-15 (5n): low toxicity, fights M. tuberculosis strains; MIC90 values range 0.73-18.8 μg/mL.Fórmula:C21H29FN2Cor e Forma:SolidPeso molecular:328.47N6-Benzoyl-2'-deoxyadenosine monohydrate
CAS:<p>N6-Benzoyl-2'-deoxyadenosine monohydrate is a nucleoside analogue that helps diagnose bacterial infections by binding to double-stranded DNA and altering its structure, which can subsequently be detected using electrophoresis.</p>Fórmula:C17H19N5O5Cor e Forma:SolidPeso molecular:373.363A 76889
CAS:A 76889 is an inhibitor of HIV-1 protease.Fórmula:C44H58N8O6Pureza:98%Cor e Forma:SolidPeso molecular:794.98RdRP-IN-4
RdRP-IN-4, an oral arylbenzohydrazide, inhibits influenza A/B by targeting PB1 of RdRP, with EC50s of 53 nM (H1N1) and 20 nM (Flu B), and aids infected mice.Fórmula:C17H17Br2N3O2Cor e Forma:SolidPeso molecular:455.14KL-50
CAS:KL-50, a selective toxin, effectively targets tumors deficient in the DNA repair protein O6-methylguanine-DNA-methyltransferase (MGMT), which corrects O6-alkylguanine lesions. This compound induces both DNA damage response pathways and cell cycle arrest in MGMT-deficient cells, regardless of mismatch repair (MMR) status. KL-50 shows promise in the study of brain tumors lacking MGMT.Fórmula:C7H7FN6O2Cor e Forma:SolidPeso molecular:226.17BI-2540
CAS:<p>BI-2540 is a HIV non-nucleoside reverse transcriptase ( NNRT ) inhibitor .</p>Fórmula:C24H15ClF5NO5Cor e Forma:SolidPeso molecular:527.83DNDI-8219
CAS:DNDI-8219 is an antitubercular agent. It has potent antileishmanial effects.Fórmula:C13H10F3N3O5Cor e Forma:SolidPeso molecular:345.23RAD51-IN-6
CAS:RAD51-IN-6, a potent RAD51 gene inhibitor, may help research mitochondrial disorders. (WO2021164746A1, cmpd 23)Fórmula:C27H40N3O5PSCor e Forma:SolidPeso molecular:549.66Antitrypanosomal agent 5
Antitrypanosal agent 5 is a selective anti-trypanosomal agent that acts on T. brucei (IC50: 1 nM) and HEK293 cells (IC50: 483.3 μM).Fórmula:C30H30N6O4SCor e Forma:SolidPeso molecular:570.66Streptothricin F
CAS:<p>Streptothricin F is a biochemical.</p>Fórmula:C19H34N8O8Cor e Forma:SolidPeso molecular:502.52SPR7
SPR7 is a potent and selective rhodesain inhibitor (Ki: 0.51 nM). SPR7 exhibited antiparasitic effects against T. b. brucei (EC50: 1.65 μM).Fórmula:C30H32ClN3O3Cor e Forma:SolidPeso molecular:518.05Imidocarb dihydrochloride monohydrate
Imidocarb dihydrochloride monohydrate is an effective antiprotozoal agent against the parasite B. bovis (IC50: 87 μg/ml).Fórmula:C19H24Cl2N6O2Cor e Forma:SolidPeso molecular:439.34Antifungal agent 27
<p>Antifungal agent 27 shows moderate action against MRSA, weak against C. albicans, with MICs of 8 μg/mL and 32 μg/mL, respectively.</p>Fórmula:C18H23N5OSCor e Forma:SolidPeso molecular:357.47Antibacterial agent 88
Antibacterial agent 88 is an effective antibacterial agent against B. subtilis (MIC: 4 μg/ml) with MIC values of ≤0.0156 μg/mL for MRSA, MRSE and S. aureus.Fórmula:C31H44N2O6SCor e Forma:SolidPeso molecular:572.76Antifungal agent 43
<p>Antifungal agent 43 inhibits biofilms with low toxicity to human cancer cells.</p>Fórmula:C24H26N4Se2Cor e Forma:SolidPeso molecular:528.41Antifungal agent 39
CAS:Antifungal agent 39 (Compound 9h) is a broad-spectrum antifungal agent.Fórmula:C23H22ClN3O5Cor e Forma:SolidPeso molecular:455.89SARS-CoV-2-IN-99
CAS:<p>SARS-CoV-2-IN-99 (compound 58) is an inhibitor of the main protease of SARS-CoV-2.</p>Fórmula:C20H16Br2NO4PCor e Forma:SolidPeso molecular:525.13Chitinase-IN-5
Chitinase-IN-5 (8i) blocks OfChi-h (IC50: 0.051 μM), has insecticidal qualities, useful for eco-friendly pest control.Fórmula:C20H21ClFN7Cor e Forma:SolidPeso molecular:413.88Metesind Glucuronate
CAS:Metesind Glucuronate is an antineoplastic. It also is a specific thymidylate synthase inhibitor.Fórmula:C29H34N4O10SCor e Forma:SolidPeso molecular:630.67Glutamate-5-kinase-IN-2
Glutamate-5-kinase-IN-2 (compound 54) is a potent G5K inhibitor with 4.2 μM MIC, potential in anti-TB research.Fórmula:C17H10ClFN2Cor e Forma:SolidPeso molecular:296.73SARS-CoV-2 nsp14-IN-2
<p>SARS-CoV-2 nsp14-IN-2: Strong Nsp14 methyltransferase inhibitor (IC50: 0.09 μM), potential for COVID-19 research.</p>Fórmula:C21H21N5O5SCor e Forma:SolidPeso molecular:455.49Gallinamide A
CAS:Gallinamide A is a potent inhibitor of cathepsin L with an IC 50 value of 17.6 pM.Fórmula:C31H52N4O7Cor e Forma:SolidPeso molecular:592.773'-NH-Tr-2',3'-DMF-ddA-5'-CE-Phosphoramidite
CAS:3'-NH-Tr-2',3'-DMF-ddA-5'-CE-Phosphoramidite serves as a precursor of adenosine nucleotide monomers used in the solid-phase synthesis of oligonucleotides, particularly for modifying oligonucleotides such as terminally modified DNA strands. It features Trityl (Tr), Cyanoethyl (CE), and Dimethylformamidine (DMF) protective groups, classifying it as a ddNTP adenosine nucleoside suitable for applications like oligonucleotide solid-phase synthesis, probe design, and chain termination sequencing.Fórmula:C41H50N9O3PCor e Forma:SolidPeso molecular:747.87Pyriftalid
CAS:Pyriftalid is a novel insecticide known for its potent inhibitory activity against a variety of pests. It is widely utilized in agriculture to effectively manage crop pests, thereby enhancing both the yield and quality of crops. Additionally, research is exploring the use of Pyriftalid in boosting plant resistance to pests and diseases.Fórmula:C15H14N2O4SCor e Forma:SolidPeso molecular:318.35Antibacterial synergist 1
Compound 20P is a potent antibacterial, inhibits biofilms with IC50 4.5 μM, and reduces pyocyanin at IC50 8.6 μM.Fórmula:C19H24N2O4Cor e Forma:SolidPeso molecular:344.4ZG297
CAS:<p>ZG297 is an agonist of Staphylococcus aureus ClpP (SaClpP) with an EC50 of 0.26 μM. It degrades SaFtsZ and inhibits bacterial cell division, exhibiting antistaphylococcal activity by inhibiting S. aureus 8325-4 and MRSA strains, with a MIC range of 0.063-256 μg/mL. In mouse models, ZG297 demonstrates anti-infective properties.</p>Fórmula:C31H35F3N4O3Cor e Forma:SolidPeso molecular:568.63Antibacterial agent 99
CAS:Compound 7b (Antibacterial agent 99) is an effective agent with antibacterial, antifungal properties and no haemolytic activity.Fórmula:C27H27BrN2Cor e Forma:SolidPeso molecular:459.42Benzisothiazolone
CAS:Benzisothiazolone is an isothiazolinone fungicide that demonstrates growth inhibitory activity against Escherichia coli ATCC 8739 and yeast NCYC 1354. It is utilized in studies investigating growth inhibition models.Fórmula:C7H5NOSCor e Forma:SolidPeso molecular:151.19Mycobacterium Tuberculosis-IN-6
CAS:Mycobacterium Tuberculosis-IN-6 (compound b1) is an inhibitor of the enoyl reductase InhA from Mycobacterium tuberculosis, with an IC50 value of 7.74 μM. It is useful in antibacterial research.Fórmula:C19H20FNOCor e Forma:SolidPeso molecular:297.367Faldaprevir sodium
CAS:Faldaprevir sodium: HCV treatment, inhibits NS3/NS4A protease, P-glycoprotein, CYP3A4, UGT1A1.Fórmula:C40H48BrN6NaO9SCor e Forma:SolidPeso molecular:891.81Methyl 3-oxodecanoate
CAS:<p>Methyl 3-oxodecanoate exhibits virulence factor activity against human pathogens and shows effects on Synechococcus elongatus (a species of fluorescent algae) as well as on culture supernatant. Additionally, Methyl 3-oxodecanoate inhibits DNA synthesis by suppressing protein synthesis at the translation initiation level.</p>Fórmula:C11H20O3Cor e Forma:SolidPeso molecular:200.275AN-12-H5
CAS:AN-12-H5 is an anti-enteroviral compound that targets the replication process of PV and EV71 viruses.Fórmula:C24H23N3O4S3Cor e Forma:SolidPeso molecular:513.65G092
G092 is a potent inhibitor of MsbA. MsbA is an ABC transporter protein. G092 has potential for antibacterial drug research.Fórmula:C23H20Cl2N2O3Cor e Forma:SolidPeso molecular:443.32MraY-IN-2
MraY-IN-2 (compound 6) is an effective inhibitor of bacterial transposase MraY (IC50=4.5 μ M), and can be used for antibacterial research.Fórmula:C16H23N3O9Cor e Forma:SolidPeso molecular:401.37RAD51-IN-5
CAS:<p>RAD51-IN-5 blocks RAD51; may aid mitochondrial disorder research. (WO2021164746A1, cmpd 3)</p>Fórmula:C26H38N4O5S2Cor e Forma:SolidPeso molecular:550.73Anti-MRSA agent 23
CAS:<p>Anti-MRSA agent 23 (compound 11) is a potent agent against methicillin-resistant Staphylococcus aureus. This compound exhibits both antibacterial and antibiofilm properties. It facilitates the healing and reconstruction of MRSA-infected skin wounds by reducing bacterial load, alleviating inflammation, and promoting angiogenesis.</p>Fórmula:C20H17N5O3SCor e Forma:SolidPeso molecular:407.446ACSS2-IN-1
CAS:ACSS2-IN-1, a potent ACSS2 inhibitor, has IC50 0.01-<1 nM; useful in cancer research.Fórmula:C27H25ClN6O2Cor e Forma:SolidPeso molecular:500.98ddCTP trisodium
ddCTP trisodium, an HIV reverse transcriptase target, aids AIDS research and DNA sequencing as a ddNTP.Fórmula:C9H13N3Na3O12P3Cor e Forma:SolidPeso molecular:517.1LN-439A
CAS:<p>LN-439A (compound LN-439A) is a novel BAP1 inhibitor that suppresses the growth of basal-like breast cancer by degrading KLF5.</p>Fórmula:C24H26FN3O4Cor e Forma:SolidPeso molecular:439.48HIV-1 inhibitor-44
HIV-1 inhibitor-44 (compound 11l) is an HIV-1 reverse transcriptase inhibitor that exhibits activity against wild-type HIV-1 strains (EC50: 0.209 μM).Fórmula:C23H26N2O4SCor e Forma:SolidPeso molecular:426.53Mt KARI-IN-1
<p>Mt KARI-IN-1 inhibits Mtb KARI with a 3.06 μM Ki, targeting tuberculosis.</p>Fórmula:C14H11N5O4S2Cor e Forma:SolidPeso molecular:377.4DL-2-Aminopimelic Acid
CAS:DL-2-Aminopimelic Acid acts as a weak agonist for glutamate receptors and also reduces the sensitivity of leech glutamate receptors to glutamate.Fórmula:C7H13NO4Cor e Forma:SolidPeso molecular:175.18SARS-CoV-2 Mpro-IN-32
CAS:SARS-CoV-2 Mpro-IN-32 (Compound 1) is a selective inhibitor of SARS-CoV-2 MPro with an IC50 value of 230 nM. In vitro, it also inhibits the replication of various SARS-CoV-2 variants.Fórmula:C34H32Cl2N4O9Cor e Forma:SolidPeso molecular:711.54Insecticidal agent 16
CAS:Insecticidal agent 16 (compound A21) exhibits insecticidal activity against Plutella xylostella, with LC50 values of 1.2 and 13.2 µg/mL respectively.Fórmula:C21H13Cl2F6N5O2SCor e Forma:SolidPeso molecular:584.32SARS-CoV-2 Mpro-IN-28
CAS:SARS-CoV-2 Mpro-IN-28 (Compound 1K) is an inhibitor of SARS-CoV-2 Mpro, exhibiting an EC50 of 24 μM.Fórmula:C14H17NO3SeCor e Forma:SolidPeso molecular:326.25WRN inhibitor 7
CAS:<p>WRN inhibitor 7 (Compound h6), a potent inhibitor of Werner syndrome helicase, demonstrates effective suppression of WRN's helicase and ATPase activities with IC50 values of 9.8 μM and 15.8 μM, respectively. This compound is utilized in the study of microsatellite instable (MSI) cancers [1].</p>Fórmula:C27H23N3O6Cor e Forma:SolidPeso molecular:485.49CTSL/CAPN1-IN-2
CAS:<p>CTSL/CAPN1-IN-2 (Compound 14b) serves as an orally active inhibitor targeting both CTSL and CAPN1, manifesting IC50 values of 6.88 nM for CTSL and 347.6 nM for CAPN1 respectively. This compound not only displays anti-inflammatory attributes but also features favorable pharmacokinetic properties. Moreover, CTSL/CAPN1-IN-2 shows extensive antiviral effects against coronaviruses by inhibiting viral entry [1].</p>Fórmula:C34H40N4O6Cor e Forma:SolidPeso molecular:600.7Uridine 3',5'-diphosphate
CAS:<p>Uridine 3′,5′-diphosphate (3′,5′-UDP; Compound pUp) serves as a competitive RNase inhibitor [1].</p>Fórmula:C9H14N2O12P2Cor e Forma:SolidPeso molecular:404.16NDM-1 inhibitor-5
CAS:NDM-1 Inhibitor-5 (compound 57) exhibits strong inhibition of NDM-1, characterized by a K i of 2.5 μM. Additionally, it demonstrates synergistic antibacterial effects when combined with meropenem [1].Fórmula:C24H23NO4Cor e Forma:SolidPeso molecular:389.44PAV-104
CAS:<p>PAV-104 inhibits the replication of SARS-CoV-2 at a MOI of 0.01. It interacts with the SARS-CoV-2 nucleocapsid (N) and disrupts its oligomerization, thereby preventing particle assembly.</p>Fórmula:C29H35N5O6SCor e Forma:SolidPeso molecular:581.68Antibacterial agent 169
CAS:<p>Antibacterial agent 169 (Compound 28), a pyrrolamide-type GyrB/ParE inhibitor, exhibits antibacterial properties by inhibiting Gyrase and Topo IV in Staphylococcus aureus. It has IC 50 values of 49 nmol/L and 1.513 μmol/L, respectively [1].</p>Fórmula:C19H25Cl2N5O3Cor e Forma:SolidPeso molecular:442.34Metallo-β-lactamase-IN-13
CAS:<p>Metallo-β-lactamase-IN-13 (Compound 13i) serves as a pan Metallo-β-Lactamase inhibitor with extended activity against Gram-negative (GN) bacteria expressing metallo-β-lactamases. It exhibits antibacterial properties effective against P. aeruginosa [1].</p>Fórmula:C15H10F3N7O2S2Cor e Forma:SolidPeso molecular:441.41BioA-IN-1
CAS:<p>BioA-IN-1 (Compound 15) is an inhibitor of the key enzyme BioA in the biotin biosynthesis pathway of Mycobacterium tuberculosis, with an IC50 value of 0.195 μM. It exhibits antibacterial activity without cytotoxicity.</p>Fórmula:C18H17NO3SCor e Forma:SolidPeso molecular:327.397Altersolanol A
CAS:<p>Altersolanol A (Stemphylin; NSC 173943) demonstrates effective antimicrobial properties, inhibiting the growth of Bacillus subtilis and Pseudomonas aeruginosa with a minimum inhibitory concentration (MIC) ranging from 25-100 μg/mL. Additionally, it shows no phytotoxic effects on Taxus at a concentration of 4 μg/μL.</p>Fórmula:C16H16O8Cor e Forma:SolidPeso molecular:336.29Antibacterial agent 188
CAS:Compound 2d (Antibacterial agent 188) serves as an antibacterial agent that suppresses the activity of dermatophytes [1].Fórmula:C12H10N4SCor e Forma:SolidPeso molecular:242.3NIP-22c
CAS:<p>NIP-22c, a novel inhibitor of coronavirus 3CL pro, exhibits antiviral activity [1]. The compound's EC50 values are 4.6 μM for Verona, 1.1 μM for Calu3, 0.1 μM for Caco2, and 0.6 μM for HBTEC-ALI.</p>Fórmula:C32H39N5O6Cor e Forma:SolidPeso molecular:589.68LpxA-IN-1
CAS:<p>LpxA-IN-1, a novel UDP-N-acetylglucosamine acyltransferase (LpxA) inhibitor exhibiting potent activity (IC 50 2 nM), effectively targets Pseudomonas aeruginosa</p>Fórmula:C21H11D7F3N5O3Cor e Forma:SolidPeso molecular:452.44SAG-524
CAS:SAG-524 is a powerful oral small molecule that inhibits HBV viral replication. In HepG2.2.15 cells, SAG-524 reduced HBV-DNA and HbsAg levels in the supernatant with IC₅₀ values of 0.92 nM and 1.4 nM, respectively [1].Fórmula:C30H32ClN5O4SCor e Forma:SolidPeso molecular:594.12Metallo-β-lactamase-IN-14
CAS:<p>Metallo-β-lactamase-IN-14 (Compound 17e) serves as an inhibitor of Metallo-β-Lactamase, displaying inhibitory activity against VIM-1 and VIM-2. This compound also exhibits antibacterial effects on Gram-negative (GN) bacteria and P. aeruginosa [1].</p>Fórmula:C20H22N8O2S2Cor e Forma:SolidPeso molecular:470.57Chitin synthase inhibitor 5
Calpain Inhibitor-2, lipophilic, inhibits calpain; shows anti-proliferative effects on melanoma, PC-3 cells; blocks 80% DU-145 cell invasion.Fórmula:C23H22BrN3O5Cor e Forma:SolidPeso molecular:500.34SARS-CoV-2 Mpro-IN-31
CAS:SARS-CoV-2 Mpro-IN-31 (Compound 18) is an inhibitor of SARS-CoV-2 MPro with an IC50 of 11 nM. Additionally, this compound effectively inhibits the enzymatic activity of the cysteine proteases cathepsin B and cathepsin L, with IC50 values of 24 nM and 1.8 nM, respectively.Fórmula:C31H34Cl2N4O7Cor e Forma:SolidPeso molecular:645.53PolQi1
CAS:<p>PolQi1 is a highly efficient and selective Polϴ (DNA polymerase theta) inhibitor with an IC50 of 2 nM, showing potential for cancer therapy.</p>Fórmula:C18H14ClF5N4O2Pureza:98.97%Cor e Forma:SolidPeso molecular:448.77PqsR-IN-2
PqsR-IN-2, potent PqsR inhibitor, curbs Pseudomonas aeruginosa communication, reduces pyocyanin, with low toxicity.Fórmula:C18H20ClN3OSCor e Forma:SolidPeso molecular:361.89MDL-860
CAS:<p>MDL-860 is a broad-spectrum antiviral compound targeting small RNA viruses and exhibits low cytotoxicity to human cells. MDL-860 is useful for research into viral infections.</p>Fórmula:C13H6Cl2N2O3Cor e Forma:SolidPeso molecular:309.104844-TFM
844-TFM, a NBTI DNA gyrase blocker, IC50: 1.5 μM, kills Mycobacterium abscessus.Fórmula:C24H25F3N4O2Cor e Forma:SolidPeso molecular:458.48C-467929
CAS:C-467929 is an inhibitor of the Nsp15 endoribonuclease, exhibiting an IC50 value of 8 μM. This compound binds to the SARS-CoVNsp15 protein and is applicable for infection research.Fórmula:C29H20N4O10Cor e Forma:SolidPeso molecular:584.49Antibacterial agent 281
CAS:Antibacterialagent 281 (Compound 95,186) effectively inhibits the growth of GAS by binding to the ligand-binding pocket of SPs0871, competing with the ligand. It exhibits concentration-dependent growth inhibition against Streptococcus pyogenes (S. pyogenes).Fórmula:C23H24N6OCor e Forma:SolidPeso molecular:400.48WR-27653
CAS:WR-27653 (RC-12), a derivative of Catechol, demonstrates significant activity against hypnozoites in the Plasmodium cynomolgi-Rhesus monkey (Macaca mulatta) model, which is considered the gold standard. Additionally, WR-27653 exhibits antimalarial properties.Fórmula:C20H36BrN3O2Cor e Forma:SolidPeso molecular:430.423EFdA-TP tetrasodium
CAS:EFdA-TP tetrasodium is a potent HIV-1 inhibitor that blocks DNA synthesis as an ICT or DCT.Fórmula:C12H11FN5Na4O12P3Pureza:98%Cor e Forma:SolidPeso molecular:621.12Chitinase-IN-4
Chitinase-IN-4 (compound 8f) is a potent and selective inhibitor of OfChi-h with an IC50 value of 0.1 μM and good insecticidal activity.Fórmula:C21H24ClN7Cor e Forma:SolidPeso molecular:409.92Chitin synthase inhibitor 9
CHS inhibitor 9: a broad-spectrum antifungal for studying fungal infections.Fórmula:C24H25N3O6Cor e Forma:SolidPeso molecular:451.47Ambelline
CAS:Ambelline has antitumor activity.Fórmula:C18H21NO5Pureza:98%Cor e Forma:SolidPeso molecular:331.36Lamivudine, (+/-)-trans-
CAS:<p>Lamivudine, a drug for HIV-1 and HBV, inhibits reverse transcriptase and resembles zalcitabine.</p>Fórmula:C8H11N3O3SPureza:98%Cor e Forma:SolidPeso molecular:229.26MurA-IN-6
CAS:MurA-IN-6 (Compound L16) is a selective MurA inhibitor with an IC50 of 26.63 μM. It exhibits antibacterial activity by inhibiting the function of MurA, a key protein essential for bacterial cell wall synthesis.Fórmula:C22H17N3O3SCor e Forma:SolidPeso molecular:403.454CB 30900
CAS:CB30900 is a novel and effective thymidylate synthase inhibitor.Fórmula:C31H32FN5O9Cor e Forma:SolidPeso molecular:637.61SMCypI C31
SMCypIC31, a non-peptide cyclophilin inhibitor, blocks PPIase at 0.1 μM IC50 and fights various HCV genotypes (EC50: 1.20-7.76 μM).Fórmula:C27H30N4O2SCor e Forma:SolidPeso molecular:474.62Pol I-IN-1
Pol I-IN-1 is a powerful inhibitor of RNA polymerase I (Pol I), specifically targeting the large catalytic subunit RPA194, demonstrating an inhibitionFórmula:C23H22N4O2Cor e Forma:SolidPeso molecular:386.45TCMDC-136230
TCMDC-136230 is a novel inhibitor of Plasmodium calcium kinetics with minimal inhibition of haemoglobin crystallisation.Fórmula:C24H34N4O2SCor e Forma:SolidPeso molecular:442.62Eravacycline dihydrochloride
CAS:<p>Eravacycline dihydrochloride (TP-434-046) is a potent and broad-spectrum antibacterial agent against six E. coli (MICs: 0.125-0.25 mg/L).</p>Fórmula:C27H33Cl2FN4O8Pureza:94.59% - 95%Cor e Forma:SolidPeso molecular:631.48HRO761
CAS:HRO761 is a potent Werne r syndrome RecQ DNA deconjugase (WRN) inhibitor that can be used to study cancers such as colon and stomach cancer.Fórmula:C31H31ClF3N9O5Pureza:98.74% - 99.62%Cor e Forma:SolidPeso molecular:702.08JTK-109
CAS:JTK-109 is an inhibitor of hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitor and inhibits G1b and G3a subgenomic replicons and recombinant enzymes.Fórmula:C37H33ClFN3O4Pureza:98.48% - 99.68%Cor e Forma:SolidPeso molecular:638.13Cap-dependent endonuclease-IN-1
CAS:Cap-dependent endonuclease-IN-1: potent, oral inhibitor with antiviral properties against influenza.Fórmula:C27H22F2N2O6SPureza:99.53% - 99.61%Cor e Forma:SolidPeso molecular:540.54CCF0058981
CAS:<p>CCF0058981: noncovalent inhibitor for SARS-CoV-2 & -1 proteases; IC50s: 68 nM (SC2) & 19 nM (SC1). Potential COVID-19 research use.</p>Fórmula:C24H19ClN6OPureza:98.94%Cor e Forma:SoildPeso molecular:442.9Vaniprevir
CAS:Vaniprevir is a competitive HCV NS3/4A protease inhibitor, an antiviral(hepatitis C virus) drug that acts directly and blocks the viral replication process.Fórmula:C38H55N5O9SPureza:97.41%Cor e Forma:SolidPeso molecular:757.94LeuRS-IN-1 hydrochloride
CAS:<p>LeuRS-IN-1 hydrochloride is a Mycobacterium tuberculosis leucyl-tRNA synthetase inhibitor with antileukemic activity and antimalarial activity.</p>Fórmula:C10H14BCl2NO3Pureza:97.34% - 99.61%Cor e Forma:SolidPeso molecular:277.94Tigemonam
CAS:<p>Tigemonam is a monobactam, a novel orally administered monobactam that protects against gram-negative aerobic bacterial pathogens. Cost-effective and quality-assured.</p>Fórmula:C12H15N5O9S2Pureza:99.03% - >99.99%Cor e Forma:SolidPeso molecular:437.41Rupintrivir
CAS:Rupintrivirvr (AG7088) is a mimetic peptide inhibitor of rhinovirus (HRV) 3C cysteine protease with antiviral activity for the study of viral infections.Fórmula:C31H39FN4O7Pureza:97.72% - 99.35%Cor e Forma:SolidPeso molecular:598.66IDX184
CAS:IDX184 is a potent, orally active, targeted HCV polymerase inhibitor and nucleoside polymerase.IDX184 effectively inhibits HCV polymerase (IC50=0.31 μM, Ki=52.3Fórmula:C25H35N6O9PSPureza:97.15%Cor e Forma:SolidPeso molecular:626.62CTPS1-IN-1
CAS:CTPS1-IN-1 is a cytidine-5′ triphosphate synthase 1 (CTPS1) inhibitor with potential antitumor activity and can be used to study autoimmune diseases.Fórmula:C21H22N6O4S2Pureza:99.46%Cor e Forma:SolidPeso molecular:486.57D75-4590
CAS:<p>D75-4590, a β-1,6-Glucan synthetase inhibitor, combats fungal infections by targeting cell walls.</p>Fórmula:C21H27N5Pureza:98.56% - 98.85%Cor e Forma:SolidPeso molecular:349.47FGI-106 tetrahydrochloride
CAS:FGI-106 tetrahydrochloride demonstrates potent inhibitory activity across a broad spectrum of viruses, including those causing hemorrhagic fevers such as EbolaFórmula:C28H42Cl4N6Pureza:99.68%Cor e Forma:SolidPeso molecular:604.48SR 11302
CAS:SR 11302 is an inhibitor of activator protein-1 (AP-1).Fórmula:C26H32O2Pureza:98.65%Cor e Forma:SolidPeso molecular:376.53Durlobactam sodium salt
CAS:Durlobactam sodium salt (ETX2514) have an IC50 values of 4, 14 and 190 nM against class A KPC-2, class C AmpC and class D OXA-24.Cost-effective and quality-assured.Fórmula:C8H10N3NaO6SPureza:97.01% - 99.03%Cor e Forma:SolidPeso molecular:299.23Reutericyclin
CAS:Reutericyclin is a unique tetramic acid, is an antibiotic produced by some strains of Lactobacillus reuteri.Fórmula:C20H31NO4Pureza:98%Cor e Forma:SolidPeso molecular:349.46Haloxon
CAS:Haloxon is an organophosphorus anthelmintic. Haloxon is used against nematodes of the abomasum and small intestine in ruminants.Fórmula:C14H14Cl3O6PCor e Forma:SolidPeso molecular:415.59L-Eflornithine monohydrochloride
CAS:L-Eflornithine is an irreversible ornithine decarboxylase (ODC) inhibitor with a KD of 1.3±0.3 µM, and a Kinact of 0.15±0.03 min-1. L-Eflornithine monohydrochloride (L-DFMO monohydrochloride) is an enantiomer of Eflornithine.Fórmula:C6H13ClF2N2O2Cor e Forma:SolidPeso molecular:218.632'-Hydroxy-4'-methylacetophenone
CAS:<p>2'-Hydroxy-4'-methylacetophenone, a phenolic compound isolated from Angelicae koreana roots possesses acaricidal property. 2'-Hydroxy-4'-methylacetophenone has acaricidal activity, it could be used in the preparation of 4'-methyl-2'-[(p-tolylsulfonyl) oxy] acetophenone.</p>Fórmula:C9H10O2Pureza:99.88%Cor e Forma:Black LiquidPeso molecular:150.17α-Terpineol
CAS:<p>Terpineol possesses antifungal activity against Trichophyton mentagrophytes, it also exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria. α-Terpineol (Terpineol) shows anticonvulsant, and anti-inflammatory activities, it inhibits the gene expression of the IL-6 receptor.</p>Fórmula:C10H18OPureza:97.55%Cor e Forma:Colorless LiquidPeso molecular:154.25CRS3123 dihydrochloride
CAS:CRS3123 (REP-3123) dihydrochloride is an orally active, fully synthetic antimicrobial agent that effectively inhibits Clostridioides difficile methionyl-tRNA synthetase (MetRS). CRS3123 dihydrochloride can be used in the study of Clostridioides difficile infection (CDI).Fórmula:C19H21Br2Cl2N3O2SCor e Forma:SolidPeso molecular:586.16Nortopixantrone
CAS:<p>Nortopixantrone(BBR 3438) is a novel 9-azacyclophenanthracene pyrazole that shows antitumor activity in a human prostate cancer model.</p>Fórmula:C20H24N6O2Pureza:>99.99%Cor e Forma:SolidPeso molecular:380.44ABT-072 potassium trihydrate
CAS:ABT-072, also known as potassium trihydrate, is a highly effective non-nucleoside inhibitor of the HCV NS5B polymerase, administered orally. This compound exhibits potent activity against HCV GT1a (with an EC50 of 1 nM) and HCV GT1b (with an EC50 of 0.3 nM).Fórmula:C24H32KN3O8SCor e Forma:SolidPeso molecular:561.69BMS-378806
<p>BMS-378806 is an HIV inhibitor with EC50: 0.85-26.5nM for various strains.</p>Fórmula:C22H22N4O4Pureza:98%Cor e Forma:SolidPeso molecular:406.432-Mercaptopyridine N-oxide sodium
CAS:<p>2-Mercaptopyridine N-oxide sodium is a useful organic compound for research related to life sciences. The catalog number is T66776 and the CAS number is 3811-73-2.</p>Fórmula:C5H4NNaOSCor e Forma:SolidPeso molecular:149.14l-Atabrine dihydrochloride
CAS:l-Atabrine dihydrochloride displays antiprion activity. l-Atabrine dihydrochloride is a less active enantiomer of quinacrine.Fórmula:C23H31Cl2N3OPureza:98%Cor e Forma:SolidPeso molecular:436.42Bacampicillin hydrochloride
CAS:Bacampicillin hydrochloride is an improved oral bioavailability penicillin antibiotic which is a prodrug of ampicillin.Fórmula:C21H28ClN3O7SPureza:98%Cor e Forma:SolidPeso molecular:501.98Erythromycylamine
CAS:Erythromycylamine is a useful organic compound for research related to life sciences. The catalog number is T64443 and the CAS number is 26116-56-3.Fórmula:C37H70N2O12Cor e Forma:SolidPeso molecular:734.969Antiviral agent 5
CAS:Antiviral agent 5 is a crucial intermediate utilized in the development of antiviral agents that specifically target 3C and 3CL proteases, which includes the SARS-CoV-2 M pro enzyme.Fórmula:C18H30N2O7Cor e Forma:SolidPeso molecular:386.445Stearyl gallate
CAS:Stearyl gallate is a useful organic compound for research related to life sciences. The catalog number is T65655 and the CAS number is 10361-12-3.Fórmula:C25H42O5Cor e Forma:SolidPeso molecular:422.606Policresulen
CAS:<p>Policresulen is a useful organic compound for research related to life sciences. The catalog number is T66902 and the CAS number is 101418-00-2.</p>Fórmula:C8H10O5SCor e Forma:SolidPeso molecular:218.22A 53868A
CAS:<p>A 53868A is an antibiotic, it is isolated from Streptomyces luridus.</p>Fórmula:C11H22N3O5PPureza:98%Cor e Forma:SolidPeso molecular:307.287Darobactin
CAS:<p>Darobactin is an antibiotic effective against critical Gram-negative pathogens, demonstrating activity both in vitro and in animal infection models [1].</p>Fórmula:C47H55N11O12Pureza:98%Cor e Forma:SolidPeso molecular:966.01MuRF1-IN-2
CAS:MuRF1-IN-2 (Example 3) is a MuRF1 inhibitor used to study conditions linked to muscle wasting, encompassing both skeletal and cardiac muscle atrophy [1].Fórmula:C23H22N2O7Pureza:98%Cor e Forma:SolidPeso molecular:438.43Tetraconazole
CAS:Tetraconazole is an agent of pesticides.Fórmula:C13H11Cl2F4N3OCor e Forma:Liquid ViscousPeso molecular:372.145'-DMT-3'-TBDMS-ibu-rG
CAS:<p>5'-DMT-3'-TBDMS-ibu-rG is a modified nucleoside employed in deoxyribonucleic acid (DNA) synthesis.</p>Fórmula:C41H51N5O8SiCor e Forma:SolidPeso molecular:769.96Ulifloxacin
CAS:Ulifloxacin is a useful organic compound for research related to life sciences. The catalog number is T65577 and the CAS number is 112984-60-8.Fórmula:C16H16FN3O3SCor e Forma:SolidPeso molecular:349.38(S)-2-Ethylbutyl 2-(((S)-(4-nitrophenoxy)(phenoxy)phosphoryl)amino)propanoate
CAS:(S)-2-Ethylbutyl 2-(((S)-(4-nitrophenoxy)(phenoxy)phosphoryl)amino)propanoate is a useful organic compound for research related to life sciences. The catalog number is T64602 and the CAS number is 1354823-36-1.Fórmula:C21H27N2O7PCor e Forma:SolidPeso molecular:450.428Pseudomonic acid C
CAS:Pseudomonic acid C is the analogue of Pseudomonic Acid D which is an antibiotic agent from Pseudomonas fluorescens.Fórmula:C26H44O8Pureza:98%Cor e Forma:SolidPeso molecular:484.62FtsZ-IN-10
CAS:<p>Compound GK02084(SC) may have activity against the GTP site of Bs‐FtsZ.</p>Fórmula:C15H13ClN2O4SPureza:98%Cor e Forma:SolidPeso molecular:352.79Lenampicillin hydrochloride
CAS:<p>Lenampicillin hydrochloride is an orally active prodrug of Ampicillin. Lenampicillin hydrochloride is an effective beta-lactam antibacterial agent that inhibits bacterial penicillin-binding proteins. It is applied in the investigation of suppurative skin </p>Fórmula:C21H24ClN3O7SPureza:98%Cor e Forma:SolidPeso molecular:497.95Rhizocticin A
CAS:Rhizocticin A is a potential inhibitor of threonine synthase.Fórmula:C11H22N5O6PPureza:98%Cor e Forma:SolidPeso molecular:351.3Phosalacine
CAS:<p>Phosalacine, isolated from Kitasatosporia phosalacinea, is a new herbicidal antibiotic that contains phosphinothricin.</p>Fórmula:C14H28N3O6PPureza:98%Cor e Forma:SolidPeso molecular:365.367Ramifenazone
CAS:Ramifenazone is a drug of nonsteroidal anti-inflammatory.Fórmula:C14H19N3OPureza:98%Cor e Forma:SolidPeso molecular:245.32Pulcherriminic acid
CAS:<p>Pulcherriminic acid, a cyclic dipeptide, chelates Fe3+, forms pulcherrimin, and has antimicrobial properties used in food, agriculture, and medicine.</p>Fórmula:C12H20N2O4Cor e Forma:SolidPeso molecular:256.30Ethynylcytidine
CAS:<p>Ethynylcytidine is a nucleoside antimetabolite.</p>Fórmula:C11H13N3O5Pureza:98%Cor e Forma:SolidPeso molecular:267.24trans-Clopenthixol dihydrochloride
CAS:<p>Trans-Clopenthixol dihydrochloride ((E)-Clopenthixol dihydrochloride), an antibiotic without neuroleptic effects, has demonstrated in vitro efficacy against Pseudomonas aeruginosa and Plasmodium falciparum, as referenced in [1] [2].</p>Fórmula:C22H27Cl3N2OSPureza:98%Cor e Forma:SolidPeso molecular:473.89Sulfamonomethoxine sodium
CAS:<p>Sulfamonomethoxine sodium is a long-acting sulfonamide antibacterial agent utilized in blood kinetic studies; it inhibits dihydropteroate synthetase, thereby blocking folic acid synthesis [1].</p>Fórmula:C11H11N4NaO3SPureza:98%Cor e Forma:SolidPeso molecular:302.29Ethyl 4-hydroxy-2-methyl-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxide
CAS:Ethyl 4-hydroxy-2-methyl-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxide is a useful organic compound for research related to life sciences. The catalog number is T65688 and the CAS number is 24683-26-9.Fórmula:C12H13NO5SCor e Forma:SolidPeso molecular:283.3Cefetamet pivoxyl
CAS:<p>Cefetamet pivoxyl, a cephalosporin antibiotic, effectively inhibits 355 enteropathogens, including Gram-negative bacteria (ausgenommen Pseudomonas aeruginosa) and Legionella pneumophila [1].</p>Fórmula:C20H25N5O7S2Pureza:98%Cor e Forma:SolidPeso molecular:511.57Hexahydrohippuric acid
CAS:Hexahydrohippuric acid is a useful organic compound for research related to life sciences. The catalog number is T65235 and the CAS number is 32377-88-1.Fórmula:C9H15NO3Cor e Forma:SolidPeso molecular:185.223N-Butylthiophosphoric triamide
CAS:<p>N-Butylthiophosphoric triamide is a useful organic compound for research related to life sciences. The catalog number is T65336 and the CAS number is 94317-64-3.</p>Fórmula:C4H14N3PSCor e Forma:SolidPeso molecular:167.211-Naphthalenemethanol
CAS:1-Naphthalenemethanol is a natural product for research related to life sciences. The catalog number is T67143 and the CAS number is 4780-79-4.Fórmula:C11H10OCor e Forma:SolidPeso molecular:158.2Oleandomycin
CAS:Oleandomycin, a macrolide antibiotic structurally similar to Erythromycin, exhibits antimicrobial activity.Fórmula:C35H61NO12Pureza:98%Cor e Forma:White Amorphous Powder SolidPeso molecular:687.865'-O-DMT-N6-ibu-dA
CAS:5'-O-DMT-N6-ibu-dA can be utilized in the synthesis of oligodeoxyribonucleotides.Fórmula:C35H37N5O6Cor e Forma:SolidPeso molecular:623.71NSC639828
CAS:NSC639828 is an efficient inhibitor of DNA polymerase α, exhibiting a remarkable IC50 value of 70 μM. Additionally, NSC639828 demonstrates substantial antitumor activity, making it a promising candidate for cancer research.Fórmula:C18H13BrClN5O3Cor e Forma:SolidPeso molecular:462.69PqsR/LasR-IN-1
CAS:PqsR/LasR-IN-1 (Compound 2a) is a potent inhibitor of LasR and PqsR systems in P. aeruginosa. PqsR/LasR-IN-1 is also a inhibitor of hERG (IC50= 6.77 μM).Fórmula:C24H20ClNO3Cor e Forma:SolidPeso molecular:405.87TP0586532
CAS:<p>TP0586532 is effective against carbapenem-resistant Klebsiella pneumoniae and does not pose a cardiovascular risk.</p>Fórmula:C26H28N4O4Pureza:98%Cor e Forma:SolidPeso molecular:460.52Oxindole
CAS:<p>Oxindole (Indolin-2-one) is an aromatic heterocyclic building block. 2-indolinone derivatives have become lead compounds in the research of kinase inhibitors.Oxindole structure has been used in receptor tyrosine kinases (RTKs) inhibitors such as SU4984 and intedanib, the RTK family represents an important therapeutic target for anti-cancer drug development.</p>Fórmula:C8H7NOPureza:99.34%Cor e Forma:Off-White Crystalline PowderPeso molecular:133.15d-Atabrine dihydrochloride
CAS:d-Atabrine hydrochloride is the active enantiomer of quinacrine and has anti-pr virus activity.Fórmula:C23H31Cl2N3OPureza:98%Cor e Forma:SolidPeso molecular:436.42MitoE10
CAS:MitoE10 is an effective mitochondrial targeting antioxidant.Fórmula:C42H55O5PSCor e Forma:SolidPeso molecular:702.92HIV-1 integrase inhibitor
CAS:Hiv-1 integrase inhibitor is an effective anti-HIV drug.Fórmula:C11H9N3O4Pureza:98%Cor e Forma:SolidPeso molecular:247.21HBV-IN-34
CAS:<p>HBV-IN-34 (compound 17i) is a potent inhibitor of HBsAg production, demonstrating remarkable in vitro anti-HBV efficacy with EC50 values of 0.018 μM for HBV DNA</p>Fórmula:C21H19F2N7Pureza:98%Cor e Forma:SolidPeso molecular:407.42Ref: TM-T79469
Produto descontinuadoPritelivir mesylate
CAS:Pritelivir mesylate is active against herpes simplex virus types 1 and 2 (IC50: 0.02 μM against HSV1-2). Pritelivir mesylate is an inhibitor of the viral helicase-primase complex. Pritelivir mesylate shows antiviral activity in vitro and in animal modelsFórmula:C19H22N4O6S3Pureza:98%Cor e Forma:SolidPeso molecular:498.6DprE1-IN-8
CAS:<p>DprE1-IN-8 is a potent inhibitor of DprE1, exhibiting an IC50 of less than 0.75 μM.</p>Fórmula:C19H12F3N5O4SPureza:98%Cor e Forma:SolidPeso molecular:463.39Ref: TM-T79628
Produto descontinuadoPKUMDL-LTQ-301
CAS:PKUMDL-LTQ-301 is a potent inhibitor of HipA toxin. PKUMDL-LTQ-301 also inhibits E. coli persistence.Fórmula:C30H28N2O4Pureza:98%Cor e Forma:SolidPeso molecular:480.55SARS-CoV-2-IN-68
CAS:<p>SARS-CoV-2-IN-68 (compound 6C) is a covalent inhibitor of both SARS-CoV-2 PLpro and Mpro, exhibiting potent antiviral properties by targeting the Zn-finger</p>Fórmula:C14H12N2OSePureza:98%Cor e Forma:SolidPeso molecular:303.22Insecticidal agent 6
CAS:<p>Compound Im (Insecticidal agent 6) is a potent inhibitor of insect ryanodine receptors (RyRs), exhibiting an EC50 of 0.6308 µM against S.</p>Fórmula:C19H14BrCl2N5O4Pureza:98%Cor e Forma:SolidPeso molecular:527.16HBV-IN-38
CAS:<p>HBV-IN-38 (Example 193), an HBV DNA inhibitor with an EC50 value of ≤100 nM, serves as a research tool for investigating viral infections [1].</p>Fórmula:C18H16F3N5O4S2Pureza:98%Cor e Forma:SolidPeso molecular:487.48Cap-dependent endonuclease-IN-9
CAS:<p>Cap-dependent endonuclease-IN-9, a strong influenza inhibitor, shows low toxicity, good pharmacokinetics, and dynamic action.</p>Fórmula:C29H22F2N4O7SPureza:98%Cor e Forma:SolidPeso molecular:608.57Ref: TM-T72125
Produto descontinuadoYhhu6669
CAS:<p>Yhhu6669 is an anti-HBV agent that suppresses viral DNA and replication by promoting DNA-free capsid assembly, effectively reducing HBV DNA and HBcAg levels in</p>Fórmula:C29H28ClFN6O3Pureza:98%Cor e Forma:SolidPeso molecular:563.02Ref: TM-T78756
Produto descontinuado
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