Microbiologia/Virologia
Os inibidores de microbiologia e virologia são compostos que têm como alvo microrganismos, incluindo bactérias, vírus e fungos, interrompendo seu crescimento, replicação ou sobrevivência. Esses inibidores são essenciais para estudar a patogênese microbiana, entender os mecanismos de resistência e desenvolver novas terapias antimicrobianas e antivirais. Os inibidores nessa categoria são usados para combater doenças infecciosas, explorar a ecologia microbiana e investigar as interações hospedeiro-patógeno. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para microbiologia e virologia para apoiar sua pesquisa em doenças infecciosas, microbiologia e virologia.
Subcategorias de "Microbiologia/Virologia"
- Antibacteriano(2.949 produtos)
- Antibiótico(918 produtos)
- Antifecção(23 produtos)
- DHFR(32 produtos)
- Síntese de DNA/RNA(706 produtos)
- HBV(176 produtos)
- HIV Protease(447 produtos)
- HSV(91 produtos)
- Integrase(2 produtos)
- Ribossomo(13 produtos)
Exibir 2 mais subcategorias
Foram encontrados 5832 produtos de "Microbiologia/Virologia"
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Methyl 3-oxodecanoate
CAS:<p>Methyl 3-oxodecanoate exhibits virulence factor activity against human pathogens and shows effects on Synechococcus elongatus (a species of fluorescent algae) as well as on culture supernatant. Additionally, Methyl 3-oxodecanoate inhibits DNA synthesis by suppressing protein synthesis at the translation initiation level.</p>Fórmula:C11H20O3Cor e Forma:SolidPeso molecular:200.275NS2B/NS3-IN-5
<p>Compound 25b inhibits DENV2/ZIKV NS2B/NS3 proteases; IC50: ZIKV 0.67μM, DENV2 4.38μM.</p>Fórmula:C14H9IN2O3SCor e Forma:SolidPeso molecular:412.2Antibacterial agent 82
<p>Antibacterial agent 82 (compound 7p) is an antibacterial agent [1].</p>Fórmula:C22H18N2O2Cor e Forma:SolidPeso molecular:342.39MI-1851
CAS:<p>MI-1851 is a potent peptidomimetic inhibitor. MI-1851could prevent proteolytic processing of the S protein from SARSCoV-2 by endogenous furin in HEK293 cells.</p>Fórmula:C34H53N15O6Cor e Forma:SolidPeso molecular:767.88CYP2C19-IN-1
<p>CYP2C19-IN-1: potent CYP2C19 inhibitor, non-genotoxic, non-hepatotoxic, blocks RdRP (Ki: 6.16 μM), useful for ZIKV research.</p>Fórmula:C26H26N2O6SCor e Forma:SolidPeso molecular:494.56G247
<p>G247 inhibits MsbA by keeping NBDs apart, blocking ATPase activity.</p>Fórmula:C24H19Cl2FO3Cor e Forma:SolidPeso molecular:445.31MTH1 activator-1
CAS:<p>MTH1 activator-1 is an MTH1 activator that enhances endogenous MTH1 activity and significantly reduces 8-oxo-dG levels in cellular DNA. It is useful for investigating the upregulation of oxidative damage repair in nucleotide pools and examining biological effects, as well as for studies aiming to delay or prevent tumorigenesis.</p>Fórmula:C29H23F3N4O2Cor e Forma:SolidPeso molecular:516.514MAY0132
CAS:<p>MAY0132 is a potent and selective EPAC2 inhibitor with an IC50 of 0.4 μM. It significantly inhibits the replication of HMPV, AdV, and RSV, reduces cytokine/chemokine production induced by viral infections, and suppresses NF-κB activation. MAY0132 exhibits antiviral activity and can be used in respiratory virus infection research.</p>Fórmula:C16H15ClF3NCor e Forma:SolidPeso molecular:313.745epi-D-Captopril
CAS:<p>epi-D-Captopril (epi-D-SQ 14225) is a stereoisomer of Captopril and functions as an inhibitor of metallo-beta-lactamases (MBLs). The IC50 values of epi-D-Captopril for NDM-1, IMP-1, and VIM-2 are 64 μM, 173 μM, and 5.5 μM, respectively. This compound holds potential for research in MBLs-related antibiotic-resistant infections.</p>Fórmula:C9H15NO3SCor e Forma:SolidPeso molecular:217.285Mt KARI-IN-1
<p>Mt KARI-IN-1 inhibits Mtb KARI with a 3.06 μM Ki, targeting tuberculosis.</p>Fórmula:C14H11N5O4S2Cor e Forma:SolidPeso molecular:377.4Antifungal agent 11
<p>Antifungal agent 11 has a good antifungal effect.</p>Fórmula:C21H19F2N7O3S2Cor e Forma:SolidPeso molecular:519.55DHX9-IN-19
CAS:<p>DHX9-IN-19 (compound 3) is an orally active inhibitor of DHX9, playing a significant role in cancer research.</p>Fórmula:C20H21ClN4O4S2Cor e Forma:SolidPeso molecular:480.988C-467929
CAS:<p>C-467929 is an inhibitor of the Nsp15 endoribonuclease, exhibiting an IC50 value of 8 μM. This compound binds to the SARS-CoVNsp15 protein and is applicable for infection research.</p>Fórmula:C29H20N4O10Cor e Forma:SolidPeso molecular:584.49ZIKV-IN-4
<p>ZIKV-IN-4 is a low cytotoxic, acid-stable anti-ZIKV agent with an EC50 value of 3.49 μM. ZIKV-IN-4 exhibited potent inhibition of ZIKV NS5 MTase.</p>Fórmula:C33H37NO4Cor e Forma:SolidPeso molecular:511.65BRL-42715
CAS:<p>BRL-42715 is an effective inhibitor of bacterial beta-lactamases.</p>Fórmula:C10H7N4NaO3SPureza:98%Cor e Forma:SolidPeso molecular:286.24HIV-1 inhibitor-13
<p>HIV-1 inhibitor-13: oral NNRTI, IC50=0.14μM for HIV-1 RT, effective on resistant strains (EC50=2.85-18nM).</p>Fórmula:C30H32N6O3Cor e Forma:SolidPeso molecular:524.61Finafloxacin
CAS:<p>Finafloxacin is a pH-activated fluoroquinolone, most effective at pH 5.0-6.0, targeting bacterial topoisomerases, used for UTIs and H. pylori infections.</p>Fórmula:C20H19FN4O4Cor e Forma:SolidPeso molecular:398.39Saussureamine C
CAS:<p>Saussureamine C is an inhibitor of H274Y and N294S mutants.</p>Fórmula:C19H26N2O5Cor e Forma:SolidPeso molecular:362.42Furametpyr
CAS:<p>Furametpyr is a kind of low toxicity pesticides used to control plant diseases caused by various pathogenic microorganisms.</p>Fórmula:C17H20ClN3O2Pureza:98%Cor e Forma:SolidPeso molecular:333.814'-Ethynyl-2'-deoxyadenosine
CAS:<p>4'-E-dA is a potent nucleoside RT inhibitor for drug-resistant HIV (EC50: 98 nM in MT-4 cells).</p>Fórmula:C12H13N5O3Pureza:98%Cor e Forma:SolidPeso molecular:275.26L 689065
CAS:<p>L 689065 is a 5-lipoxygenase inhibitor.</p>Fórmula:C35H33ClN2O3SPureza:98%Cor e Forma:SolidPeso molecular:597.17PFK-IN-1
CAS:<p>PFK-IN-1 (compound 1) is an inhibitor of 6-phosphofructo-1-kinase (PFK), demonstrating IC50 values of 0.41 and 0.23 μM against T. brucei and T. cruzi PFK, respectively, and an ED50 of 15.18 μg/mL for T. brucei. The compound has a half-life of 9.7 minutes in rat liver microsomes and 408 minutes in mouse liver microsomes.</p>Fórmula:C18H15Cl2N3O4SCor e Forma:SolidPeso molecular:440.3Ganaplacide hydrochloride
CAS:<p>Ganaplacide hydrochloride (KAF156 HCl) is an orally administered imidazopyrimidine antimalarial agent that inhibits Plasmodium PI4K activity.</p>Fórmula:C22H24ClF2N5OPureza:93.97%Cor e Forma:SoildPeso molecular:447.91(Rac)-Plevitrexed
CAS:<p>(Rac)-Plevitrexed is a racemate of Plevitrexed. Plevitrexed is an orally active and potent inhibitor of thymidylate synthase (TS).</p>Fórmula:C26H25FN8O4Pureza:98%Cor e Forma:SolidPeso molecular:532.53DNA polymerase-IN-6
CAS:<p>DNA polymerase-IN-6 (Compound 27) exhibits inhibitory activity against DNA polymerase, with EC50 values of 0.33 µM for HCMV, 1.9 µM for HSV-1, 0.76 µM for HSV-2, and 0.066 µM for EBV.</p>Fórmula:C26H28ClFN8O4Cor e Forma:SolidPeso molecular:571.003Antibacterial agent 66
<p>Compound 6q, a trifluoromethylpyridine oxadiazole, targets Xanthomonas oryzae with EC50 of 7.2 μg/mL.</p>Fórmula:C17H10ClF6N3O2SCor e Forma:SolidPeso molecular:469.79ACHN-975 TFA
CAS:<p>ACHN-975 TFA is a selective LpxC inhibitor with a subnanomolar inhibitory. It is against a wide range of gram-negative bacterias with low MIC values (≤1 μg/mL).</p>Fórmula:C22H24F3N3O6Pureza:98%Cor e Forma:SolidPeso molecular:483.4377KPC-2-IN-2
<p>KPC-2-IN-2 (6c) inhibits KPC-2 enzyme in Klebsiella pneumoniae (Ki 0.038 μM) and boosts cefotaxime in E. coli KPC-2.</p>Fórmula:C12H10BN3O2SCor e Forma:SolidPeso molecular:271.1WRN inhibitor 13
CAS:<p>WRN inhibitor 13 is an inhibitor of the WRN helicase with a pIC50 value ranging from 6 to 7.</p>Fórmula:C16H20N2O5SCor e Forma:SolidPeso molecular:352.405Chitinase-IN-4
<p>Chitinase-IN-4 (compound 8f) is a potent and selective inhibitor of OfChi-h with an IC50 value of 0.1 μM and good insecticidal activity.</p>Fórmula:C21H24ClN7Cor e Forma:SolidPeso molecular:409.92QPX7728 methoxy acetoxy methy ester
CAS:<p>QPX7728 methoxy acetoxy methy ester is an inhibitor of boronic acid β-lactamase.</p>Fórmula:C14H14BFO7Pureza:98%Cor e Forma:SolidPeso molecular:324.07Anti-Trypanosoma cruzi agent-2
<p>Compd 3b: anti-trypanosomal, IC50 0.51 μM (NINOA), 3.06 μM (INC-5), also combats T. gondii.</p>Fórmula:C17H10ClNO5Cor e Forma:SolidPeso molecular:343.72RdRP-IN-5
CAS:<p>RdRP-IN-5 (compound 20), a potent inhibitor of the influenza virus RNA-dependent RNA polymerase (RdRP), has potential application in influenza research [1].</p>Fórmula:C23H21N3O5Pureza:98%Cor e Forma:SolidPeso molecular:419.43NNRT-IN-5
CAS:<p>NNRT-IN-5 (compound 10d) is an orally available non-nucleoside reverse transcriptase (Reverse Transcriptase) inhibitor.</p>Fórmula:C27H22N8Cor e Forma:SolidPeso molecular:458.52Polθ-IN-5
CAS:<p>Polθ-IN-5 (Compound 139) is an inhibitor of DNA polymerase theta (Polθ) that exhibits antitumor activity.</p>Fórmula:C23H18ClF2N7O3SCor e Forma:SolidPeso molecular:545.95SARS-CoV-2 Mpro-IN-31
CAS:<p>SARS-CoV-2 Mpro-IN-31 (Compound 18) is an inhibitor of SARS-CoV-2 MPro with an IC50 of 11 nM. Additionally, this compound effectively inhibits the enzymatic activity of the cysteine proteases cathepsin B and cathepsin L, with IC50 values of 24 nM and 1.8 nM, respectively.</p>Fórmula:C31H34Cl2N4O7Cor e Forma:SolidPeso molecular:645.53Doxazosin impurity 12
CAS:<p>Doxazosin impurity 12 acts as an inhibitor of CTX-M β-lactamase (Beta-lactamase) with a Ki value of 0.7 mM against CTX-M.</p>Fórmula:C10H6O5SCor e Forma:SolidPeso molecular:238.217MDL-860
CAS:<p>MDL-860 is a broad-spectrum antiviral compound targeting small RNA viruses and exhibits low cytotoxicity to human cells. MDL-860 is useful for research into viral infections.</p>Fórmula:C13H6Cl2N2O3Cor e Forma:SolidPeso molecular:309.104Piperacillin hydrate
CAS:<p>Piperacillin hydrate is a semisynthetic broad-spectrum β-lactam antibiotic. It exhibits potent bactericidal activity against Gram-negative bacteria and some Gram-positive bacteria by targeting penicillin-binding proteins. Piperacillin hydrate is frequently combined with the β-lactamase inhibitor Tazobactam for enhanced efficacy.</p>Fórmula:C23H29N5O8SCor e Forma:SolidPeso molecular:535.57Enantiomer of Sofosbuvir
<p>Inactive enantiomer of Sofosbuvir, used for chronic hepatitis C; lacks reported biological activity.</p>Fórmula:C22H29FN3O9PPureza:98%Cor e Forma:SolidPeso molecular:529.45MBX-1162
CAS:<p>MBX-1162, a bis-indole compound, has demonstrated unique substrate specificity related to MepA and MepR in studies investigating its resistance mechanisms in Staphylococcus aureus. It has not shown cross-resistance with related compounds.</p>Fórmula:C30H28N6Cor e Forma:SolidPeso molecular:472.58SARS-CoV-2-IN-99
CAS:<p>SARS-CoV-2-IN-99 (compound 58) is an inhibitor of the main protease of SARS-CoV-2.</p>Fórmula:C20H16Br2NO4PCor e Forma:SolidPeso molecular:525.13Lamivudine, (+/-)-trans-
CAS:<p>Lamivudine, a drug for HIV-1 and HBV, inhibits reverse transcriptase and resembles zalcitabine.</p>Fórmula:C8H11N3O3SPureza:98%Cor e Forma:SolidPeso molecular:229.26Cefempidone
CAS:<p>Cefempidone (GR 50692) is a third-generation cephalosporin antibiotic. It exhibits antibacterial activity by inhibiting penicillin-binding proteins involved in the synthesis of bacterial cell walls.</p>Fórmula:C22H21N7O6S2Peso molecular:543.58Pks13-TE inhibitor 4
CAS:<p>Pks13-TE inhibitor 4 (compound 44) is a potent inhibitor from the thiazole series that effectively targets Pks13 to combat tuberculosis (TB) and addresses drug resistance.</p>Fórmula:C26H25N5O6Peso molecular:503.51Hyalodendrin
CAS:<p>Hyalodendrin ((+)-Hyalodendrin) acts as a fungal growth inhibitor, specifically targeting wood decay fungi. It exhibits low phytotoxicity and possesses an acute toxicity (LD50) level of 75 mg/kg in mice.</p>Fórmula:C14H16N2O3S2Cor e Forma:SolidPeso molecular:324.42Metallo-β-lactamase-IN-13
CAS:<p>Metallo-β-lactamase-IN-13 (Compound 13i) serves as a pan Metallo-β-Lactamase inhibitor with extended activity against Gram-negative (GN) bacteria expressing metallo-β-lactamases. It exhibits antibacterial properties effective against P. aeruginosa [1].</p>Fórmula:C15H10F3N7O2S2Cor e Forma:SolidPeso molecular:441.41Antifungal agent 100
CAS:<p>Antifungal agent 100 (compound 3i) demonstrates notable antifungal activity, exhibiting an EC 50 of 0.33 mg/L against S. sclerotiorum. It also possesses an IC 50 value of 0.63 mg/mL targeting the Succinate dehydrogenase (SDH) of the same organism [1].</p>Fórmula:C23H21N3O4SCor e Forma:SolidPeso molecular:435.5NIP-22c
CAS:<p>NIP-22c, a novel inhibitor of coronavirus 3CL pro, exhibits antiviral activity [1]. The compound's EC50 values are 4.6 μM for Verona, 1.1 μM for Calu3, 0.1 μM for Caco2, and 0.6 μM for HBTEC-ALI.</p>Fórmula:C32H39N5O6Cor e Forma:SolidPeso molecular:589.68HBV/HDV-IN-3
CAS:<p>HBV/HDV-IN-3 (Compd 1) acts as a dual inhibitor for HBV and HDV, demonstrating an efficacy (EC 50) below 50 nM against HBV .</p>Fórmula:C28H27BrF3N5O3Cor e Forma:SolidPeso molecular:618.44HIV-1 inhibitor-61
CAS:<p>HIV-1 Inhibitor-61 (2c) serves as a potent inhibitor of HIV-1 reverse transcriptase, exhibiting an EC50 value of 0.07 nM in NL4-3 wt MT-4 cells [1].</p>Fórmula:C24H24F2N2O2SCor e Forma:SolidPeso molecular:442.52Antibacterial agent 172
CAS:<p>Antibacterial Agent 172 (Compound 6a), a <i>Clostridioides difficile (Cd) SpoVD inhibitor with an IC50 value of 89 nM, effectively inhibits the sporulation of Clostridioides difficile. It is useful for research on bacterial infections [1].</p>Fórmula:C21H21N9O5S2Cor e Forma:SolidPeso molecular:543.58Antibacterial agent 174
CAS:<p>Compound 174 (Compound 5g), an antibacterial agent, exhibits potent anti-infective properties in vivo along with appreciable pharmacokinetic profiles. This highly active substance demonstrates favorable biofilm removal capabilities, low hemolysis, and acceptable mammalian cell toxicity [1].</p>Fórmula:C25H30FN2NaO5Cor e Forma:SolidPeso molecular:480.5CMX990
CAS:<p>CMX990, a SARS-CoV-2 3CL protease inhibitor, exhibits EC90 values of 9.6 nM in human bronchial epithelial cells (HBECs) and 101 nM in HeLa-ACE2 cells. It also demonstrates good ADME and pharmacokinetic properties [1].</p>Fórmula:C22H32F3N3O6Cor e Forma:SolidPeso molecular:491.50LpxA-IN-1
CAS:<p>LpxA-IN-1, a novel UDP-N-acetylglucosamine acyltransferase (LpxA) inhibitor exhibiting potent activity (IC 50 2 nM), effectively targets Pseudomonas aeruginosa</p>Fórmula:C21H11D7F3N5O3Cor e Forma:SolidPeso molecular:452.44iPAF1C
CAS:<p>iPAF1C is a powerful inhibitor of the polymerase-associated factor 1 complex (PAF1C) and exhibits anti-HIV activity [1].</p>Fórmula:C27H26BrFN4OCor e Forma:SolidPeso molecular:521.42SAG-524
CAS:<p>SAG-524 is a powerful oral small molecule that inhibits HBV viral replication. In HepG2.2.15 cells, SAG-524 reduced HBV-DNA and HbsAg levels in the supernatant with IC₅₀ values of 0.92 nM and 1.4 nM, respectively [1].</p>Fórmula:C30H32ClN5O4SCor e Forma:SolidPeso molecular:594.12Metallo-β-lactamase-IN-14
CAS:<p>Metallo-β-lactamase-IN-14 (Compound 17e) serves as an inhibitor of Metallo-β-Lactamase, displaying inhibitory activity against VIM-1 and VIM-2. This compound also exhibits antibacterial effects on Gram-negative (GN) bacteria and P. aeruginosa [1].</p>Fórmula:C20H22N8O2S2Cor e Forma:SolidPeso molecular:470.57BPR3P0128
CAS:<p>BPR3P0128, a non-nucleoside RNA-dependent RNA polymerase (RdRp) inhibitor, is effective orally and can inhibit various SARS-CoV-2 variants. It exhibits EC 50 values of 0.62 µM for SARS-CoV-2 and 0.14 µM for HCoV-229E, demonstrating potent anti-pancoronavirus activity at submicromolar concentrations. Additionally, BPR3P0128 displays synergistic antiviral effects when used in combination with Remdesivir [1].</p>Fórmula:C22H18BrN3O2Cor e Forma:SolidPeso molecular:436.30InhA-IN-7
CAS:<p>InhA-IN-7 (Compound 11), a derivative of Triclocan, shows inhibitory activity against enoyl-acyl carrier protein reductase (InhA) with an IC50 of 96 nM. It effectively inhibits the proliferation of both wildtype and mutant strains of Mycobacterium tuberculosis, exhibiting minimum inhibitory concentrations (MICs) ranging from 19 to 75 μM [1].</p>Fórmula:C17H18Cl2O2Cor e Forma:SolidPeso molecular:325.23RhlR antagonist 1
<p>RhlR antagonist 1: IC50 of 26 μM, selective for RhlR, inhibits P. aeruginosa biofilm and virulence factors.</p>Fórmula:C12H10F2OCor e Forma:SolidPeso molecular:208.2JPL
CAS:<p>JPL is an InhA-cofactor-ligand 3FNG inhibitor and is used for the study of tuberculosis [1].</p>Fórmula:C19H20Cl2O2Cor e Forma:SolidPeso molecular:351.27PqsR-IN-2
<p>PqsR-IN-2, potent PqsR inhibitor, curbs Pseudomonas aeruginosa communication, reduces pyocyanin, with low toxicity.</p>Fórmula:C18H20ClN3OSCor e Forma:SolidPeso molecular:361.89HIV-1 inhibitor-14
<p>HIV-1 inhibitor-14: potent, broad HIV-1 RT inhibitor. IC50=0.14μM. Effective against wild-type and resistant strains, EC50=5.79-28.3nM.</p>Fórmula:C29H32N6O4SCor e Forma:SolidPeso molecular:560.67Enzyme-IN-3 disodium
CAS:<p>Enzyme-IN-3 disodium (compound 7) is a selective inhibitor of Mycobacterium tuberculosis shikimate kinase with an IC50 of 1.6 μM. Additionally, Enzyme-IN-3 disodium exhibits antibacterial properties.</p>Fórmula:C20H13N3Na2O8S2Cor e Forma:SolidPeso molecular:533.442HBV-IN-18
<p>HBV-IN-18 (Compound 3) is an HBV capsid assembly modulator (CpAM) (EC50: 2790 nM).</p>Fórmula:C17H15F6N5O2Cor e Forma:SolidPeso molecular:435.32N'-(2-Fluorophenyl)pyrazine-2-carbohydrazide
<p>N'-(2-Fluorophenyl)pyrazine-2-carbohydrazide is a Ole1p desaturase inhibitor as well as antifungal agent [1].</p>Fórmula:C11H9FN4OCor e Forma:SolidPeso molecular:232.21844-TFM
<p>844-TFM, a NBTI DNA gyrase blocker, IC50: 1.5 μM, kills Mycobacterium abscessus.</p>Fórmula:C24H25F3N4O2Cor e Forma:SolidPeso molecular:458.48SARS-CoV-2-IN-8
<p>SARS-CoV-2-IN-8 is a major protease inhibitor of SARS-CoV-2 (IC50: 0.75 μM).</p>Fórmula:C35H38N6O3Cor e Forma:SolidPeso molecular:590.71OPC-167832
CAS:<p>OPC-167832: oral dprE1 inhibitor, IC50 0.258 μM, anti-tuberculosis, for Mycobacterium tuberculosis research.</p>Fórmula:C21H20ClF3N2O4Cor e Forma:SolidPeso molecular:456.84Elongation factor P-IN-2
<p>Elongation factor P-IN-2, a β-lysine derivative, is a potent EFP inhibitor reducing E. coli growth.</p>Fórmula:C16H35N3O2Cor e Forma:SolidPeso molecular:301.47DENV-IN-6
CAS:<p>DENV-IN-6, a potent anti-DENV (I-IV) and HIV-1 IIIB inhibitor with EC50 ranging 6.8-17.5 μM for DENV and EC50 0.0181 μM for HIV-1.</p>Fórmula:C23H26ClFN4OSCor e Forma:SolidPeso molecular:461CB 30900
CAS:<p>CB30900 is a novel and effective thymidylate synthase inhibitor.</p>Fórmula:C31H32FN5O9Cor e Forma:SolidPeso molecular:637.61HIV-1 inhibitor-8
<p>HIV-1 inhibitor-8: potent oral NNRTI, low toxicity, IC50: 0.081 μM, effective on multiple strains, EC50: 4.44-54.5 nM.</p>Fórmula:C25H21N5OSCor e Forma:SolidPeso molecular:439.53SMCypI C31
<p>SMCypIC31, a non-peptide cyclophilin inhibitor, blocks PPIase at 0.1 μM IC50 and fights various HCV genotypes (EC50: 1.20-7.76 μM).</p>Fórmula:C27H30N4O2SCor e Forma:SolidPeso molecular:474.62Pol I-IN-1
<p>Pol I-IN-1 is a powerful inhibitor of RNA polymerase I (Pol I), specifically targeting the large catalytic subunit RPA194, demonstrating an inhibition</p>Fórmula:C23H22N4O2Cor e Forma:SolidPeso molecular:386.45TCMDC-136230
<p>TCMDC-136230 is a novel inhibitor of Plasmodium calcium kinetics with minimal inhibition of haemoglobin crystallisation.</p>Fórmula:C24H34N4O2SCor e Forma:SolidPeso molecular:442.62L-2'-Fd4C
CAS:<p>L-2'-Fd4C is an L-nucleoside analogue with both anti-human immunodeficiency virus (HIV) and anti-hepatitis B virus (HBV) activity [1].</p>Fórmula:C9H10FN3O3Cor e Forma:SolidPeso molecular:227.19Antifungal agent 27
<p>Antifungal agent 27 shows moderate action against MRSA, weak against C. albicans, with MICs of 8 μg/mL and 32 μg/mL, respectively.</p>Fórmula:C18H23N5OSCor e Forma:SolidPeso molecular:357.47Rubropunctatin
CAS:<p>Rubropunctatin is a monascus pigment with very potent cancer cell proliferation inhibitory effects.</p>Fórmula:C21H23NO4Cor e Forma:SolidPeso molecular:353.41Antibacterial agent 88
<p>Antibacterial agent 88 is an effective antibacterial agent against B. subtilis (MIC: 4 μg/ml) with MIC values of ≤0.0156 μg/mL for MRSA, MRSE and S. aureus.</p>Fórmula:C31H44N2O6SCor e Forma:SolidPeso molecular:572.76Antifungal agent 43
<p>Antifungal agent 43 inhibits biofilms with low toxicity to human cancer cells.</p>Fórmula:C24H26N4Se2Cor e Forma:SolidPeso molecular:528.41Antibacterial agent 118
<p>Antibacterial agent 118, potent against various mycobacteria, has MIC values ranging from 10.2 to 163.0 μM. Useful in TB research.</p>Fórmula:C19H21N5O2SCor e Forma:SolidPeso molecular:383.47LpxC-IN-10
CAS:<p>LpxC-IN-10 is a selective LpxC inhibitor with an MIC of 0.5 μg/mL against E. coli and K. pneumoniae and is capable of being used to study bacterial infections.</p>Fórmula:C30H31N5O3Cor e Forma:SolidPeso molecular:509.6Antitubercular agent-16
<p>Compound 5q is a potent antitubercular with low MIC90 values (0.40-23.51 μg/mL) against M. tuberculosis strains, showing minimal cytotoxicity.</p>Fórmula:C21H27N3SCor e Forma:SolidPeso molecular:353.52Antifungal agent 39
CAS:<p>Antifungal agent 39 (Compound 9h) is a broad-spectrum antifungal agent.</p>Fórmula:C23H22ClN3O5Cor e Forma:SolidPeso molecular:455.89Cap-dependent endonuclease-IN-5
CAS:<p>Cap-dependent endonuclease-IN-5 inhibits CEN and fights influenza with low toxicity and good in vivo properties.</p>Fórmula:C27H21F2N3O4S2Cor e Forma:SolidPeso molecular:553.60cis-RdRP-IN-5
<p>Cis-RdRP-IN-5 is an effective inhibitor of the influenza virus RNA-dependent RNA polymerase (RdRP), employed in influenza virus research.</p>Fórmula:C23H21N3O5Cor e Forma:SolidPeso molecular:419.43HBV-IN-31
CAS:<p>HBV-IN-31: strong cccDNA inhibitor, anti-HBV, IC50=0.13 µM HBsAg, hampers cell growth.</p>Fórmula:C23H18ClNO6Cor e Forma:SolidPeso molecular:439.85RmlA-IN-2
<p>RmlA-IN-2: Strong RmlA blocker, hinders l-rhamnose synthesis & alters bacterial wall permeability (IC50: 0.303 μM).</p>Fórmula:C22H26BrN5O4SCor e Forma:SolidPeso molecular:536.44Antifungal agent 42
<p>Antifungal 42 blocks biofilm formation and inhibits C.albicans' CYP51.</p>Fórmula:C22H20Cl2N4Se2Cor e Forma:SolidPeso molecular:569.25Gallinamide A
CAS:<p>Gallinamide A is a potent inhibitor of cathepsin L with an IC 50 value of 17.6 pM.</p>Fórmula:C31H52N4O7Cor e Forma:SolidPeso molecular:592.77Acetomycin
CAS:<p>Acetomycin, a γ-lactone from S. ramulosus, halts HCT-8 colon and L1210 leukemia cell growth.</p>Fórmula:C10H14O5Cor e Forma:SolidPeso molecular:214.22SP inhibitor 1
<p>SP inhibitor 1 blocks SARS-CoV-2 replication in vitro (0.3250<5.98 μM) and targets SP protein (IC50: 3.26 μM) with antiviral effects.</p>Fórmula:C36H38N2O2Cor e Forma:SolidPeso molecular:530.7LasR-IN-3
<p>LasR-IN-3 inhibits LasR in Pseudomonas, disrupting its dimer, causing loss of function.</p>Fórmula:C22H19N3O2Cor e Forma:SolidPeso molecular:357.41RAD51-IN-6
CAS:<p>RAD51-IN-6, a potent RAD51 gene inhibitor, may help research mitochondrial disorders. (WO2021164746A1, cmpd 23)</p>Fórmula:C27H40N3O5PSCor e Forma:SolidPeso molecular:549.66Beclabuvir
CAS:<p>Beclabuvir blocks HCV NS5B polymerase at thumb site 1, effective on genotypes 1, 3, 4, 5 with IC50 <28 nM.</p>Fórmula:C36H45N5O5SPureza:99.87% - 99.93%Cor e Forma:SolidPeso molecular:659.84ONO-5334
CAS:<p>ONO-5334: selective cathepsin K inhibitor, potential for osteoporosis study; Ki: 0.10 nM (human), 0.049 nM (rabbit), 0.85 nM (rat).</p>Fórmula:C21H34N4O4SPureza:98.22% - 99.60%Cor e Forma:SolidPeso molecular:438.58HBV-IN-19 TFA
CAS:<p>HBV-IN19 TFA suppresses HBsAg, hampers HBV infection, and aids in HBV research.</p>Fórmula:C26H31F3N2O8Cor e Forma:SolidPeso molecular:556.53HT1171
CAS:<p>HT1171 is a potent and selective inhibitor of the Mycobacterium tuberculosis proteasome. It exhibits strong antitubercular activity against Mycobacterium tuberculosis H37Rv, with a MIC90 of 2 μg/mL and MIC of 4 μg/mL. At a concentration of 100 μM, HT1171 shows an inhibition rate of 53.8% against normal human liver cells (L02). HT1171 is applicable in antituberculosis drug research.</p>Fórmula:C7H4N2O4S2Cor e Forma:SolidPeso molecular:244.248Antibacterial agent 261
CAS:<p>Antibacterialagent 261 (compound 43) is a potent inhibitor of the peptide deformylase (PDF) enzyme, demonstrating IC50 values of 2.5 nM against Staphylococcus aureus (S. aureus) and 10.6 nM against Escherichia coli (E. coli).</p>Fórmula:C18H24N4O3S2Cor e Forma:SolidPeso molecular:408.538PptT-IN-3
<p>PptT-IN-3 (5p), an inhibitor of PptT in Mycobacterium tuberculosis, IC50=3.5μM, is key for TB research.</p>Fórmula:C16H27N5O3SCor e Forma:SolidPeso molecular:369.48TAN-1057C
CAS:<p>TAN-1057C is a potent antibiotic with antimicrobial activity against both Gram-negative and Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus (MRSA).</p>Fórmula:C13H25N9O3Cor e Forma:SolidPeso molecular:355.4PfCLK3-IN-1
<p>PfCLK3-IN-1 (Compound 4) serves as a covalent inhibitor of the malaria parasite CLK3 (Pf CLK3) under alkaline conditions, with a pEC50 of 7.1. It inhibits the maturation of gametocytes during the sexual stage of the parasite, thereby hindering transmission. Additionally, PfCLK3-IN-1 effectively suppresses the Dd2-B2 clone of the malaria parasite, exhibiting an IC50 of 239.5 nM.</p>Fórmula:C28H27ClN4O4Cor e Forma:SolidPeso molecular:518.99AV-5080
CAS:<p>AV-5080 is an orally active neuraminidase (neuraminidase) inhibitor that is utilized in the research of both Type A and Type B influenza viruses.</p>Fórmula:C15H25FN4O4Cor e Forma:SolidPeso molecular:344.38Anti-MRSA agent 19
CAS:<p>Anti-MRSA agent 19 (Compound 1) is an antibiotic that exhibits activity against Staphylococcus aureus. It is active against 40 clinical isolates from the CDC, representing diverse bacterial species with various resistance factors, including resistance to vancomycin, aminoglycoside/tetracycline, and oxazolidinone (median MIC=4 μg/mL).</p>Fórmula:C15H10Cl3NO4Cor e Forma:SolidPeso molecular:374.6Isazofos
CAS:<p>Isazofos is a broad-spectrum organophosphate insecticide and nematicide effective in controlling a variety of lawn pests, such as nematodes (Radopholus similis). It also demonstrates efficacy in managing rice gall midge.</p>Fórmula:C9H17ClN3O3PSCor e Forma:SolidPeso molecular:313.74Carbonic anhydrase inhibitor 28
<p>Carbonic anhydrase inhibitor28 (Compound 11) serves as an inhibitor for the Pseudomonas aeruginosa carbonic anhydrase. It exhibits antibacterial activity, with minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) values of 0.5 and 1 μg/mL, respectively, against P. aeruginosa. Carbonic anhydrase inhibitor28 is utilized in research focused on anti-infection applications.</p>Fórmula:C24H24FN5O7SCor e Forma:SolidPeso molecular:545.54VNI
CAS:<p>VNI is an effective inhibitor of CYP51. It suppresses sterol synthesis in Trypanosoma cruzi, exhibiting anti-Trypanosoma cruzi activity.</p>Fórmula:C26H19Cl2N5O2Cor e Forma:SolidPeso molecular:504.37Werner syndrome RecQ helicase-IN-2
CAS:<p>Werner syndrome RecQ helicase-IN-2 is a potent Werner syndrome RecQ DNA helicase (WRN) inhibitor, useful in research on colorectal and gastric cancers.</p>Fórmula:C32H34F3N9O5Pureza:99.02%Cor e Forma:SolidPeso molecular:681.67Antibacterial agent 112
<p>Compound 112: Powerful antibacterial, MIC 1250 μM against B. subtilis, E. coli, E. faecalis, S. typhimurium, S. aureus; also an HIV-1 antibody.</p>Fórmula:C35H23N5O5Cor e Forma:SolidPeso molecular:593.5920S Proteasome-IN-4
CAS:<p>20S Proteasome-IN-4: brain-penetrant, parasite-specific, oral, inhibits T.b. brucei proteasome (IC50: 6.3nM), for HAT research.</p>Fórmula:C20H18ClF2N3O3Cor e Forma:SolidPeso molecular:421.83bc1 Complex-IN-1
CAS:<p>Bc1 Complex-IN-1 (compound 12g) is a potent inhibitor of the bc1 complex, demonstrating fungicidal properties against cucumber downy mildew (CDM).</p>Fórmula:C16H22N6O5S2Cor e Forma:SolidPeso molecular:442.513Cap-dependent endonuclease-IN-10
CAS:<p>Cap-dependent endonuclease-IN-10, with low toxicity & good stability, effectively inhibits flu viruses and shows promise against A, B, C types.</p>Fórmula:C25H18F2N4O5SCor e Forma:SolidPeso molecular:524.50PfPKG-IN-1
<p>PfPKG-IN-1, an imidazole-based inhibitor, targets the Plasmodium falciparum cyclic guanosine monophosphate-dependent protein kinase (PfPKG).</p>Fórmula:C24H22ClN7OSCor e Forma:SolidPeso molecular:492Antimicrobial agent-29
CAS:<p>Antimicrobial Agent-29 (Compound C35) influences the interaction between human hemoglobin and the Staphylococcus aureus IsdB hemophore. This compound facilitates the identification of IsdB:Hb PPI inhibitors [1].</p>Fórmula:C19H14N4O4SCor e Forma:SolidPeso molecular:394.4GRL-190-21
CAS:<p>GRL-190-21 (compound 5e), an inhibitor of SARS-Cov-2-Mpro, shows potent antiviral activity, with a K_i of 0.04 nM and an EC_50 of 0.26 μM in VeroE6 cells. It significantly reduces the infectivity, replication, and cytopathic effect of SARS-CoV-2 without notable toxicity [1].</p>Fórmula:C24H34F3N5O4Cor e Forma:SolidPeso molecular:513.55Antibacterial agent 188
CAS:<p>Compound 2d (Antibacterial agent 188) serves as an antibacterial agent that suppresses the activity of dermatophytes [1].</p>Fórmula:C12H10N4SCor e Forma:SolidPeso molecular:242.3Altersolanol A
CAS:<p>Altersolanol A (Stemphylin; NSC 173943) demonstrates effective antimicrobial properties, inhibiting the growth of Bacillus subtilis and Pseudomonas aeruginosa with a minimum inhibitory concentration (MIC) ranging from 25-100 μg/mL. Additionally, it shows no phytotoxic effects on Taxus at a concentration of 4 μg/μL.</p>Fórmula:C16H16O8Cor e Forma:SolidPeso molecular:336.29VV261
CAS:<p>VV261 is an orally active inhibitor of the Influenza Virus. It exhibits activity against the Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV) and the Lymphocytic Choriomeningitis Virus (LCMV), with EC50 values of 0.89 and 0.15, respectively.</p>Fórmula:C28H34FN3O11Cor e Forma:SolidPeso molecular:607.58Menoctone
CAS:<p>Menoctone is an orally effective antimalarial agent that inhibits blood-induced rodent malaria. It enhances the antimalarial effects of chloroquine or quinine, making it useful for malaria research.</p>Fórmula:C24H32O3Cor e Forma:SolidPeso molecular:368.51WRN inhibitor 7
CAS:<p>WRN inhibitor 7 (Compound h6), a potent inhibitor of Werner syndrome helicase, demonstrates effective suppression of WRN's helicase and ATPase activities with IC50 values of 9.8 μM and 15.8 μM, respectively. This compound is utilized in the study of microsatellite instable (MSI) cancers [1].</p>Fórmula:C27H23N3O6Cor e Forma:SolidPeso molecular:485.49Antibacterial agent 204
CAS:<p>Antibacterial agent 204 (Compd P2-56-3) enhances the activity of Rifampin (RIF) against Acinetobacter baumannii and Klebsiella pneumoniae by disrupting the outer membrane of A. baumannii. T [1].</p>Fórmula:C14H18N2Cor e Forma:SolidPeso molecular:214.31HKI12134085
CAS:<p>HKI12134085 (compound 3), an orally administered nitrobenzothiazinone (BTZ) derivative, demonstrates antibacterial efficacy against Mycobacterium tuberculosis. This compound exhibits significant in vivo inhibitory potency within a BALB/c mouse model of Mycobacterium tuberculosis infection [1].</p>Fórmula:C18H18F3N3O5SCor e Forma:SolidPeso molecular:445.41Arterolane maleate
CAS:<p>Arterolane, an adenosine triphosphatase inhibitor, is used potentially for the treatment of malaria.</p>Fórmula:C26H40N2O8Pureza:98%Cor e Forma:SolidPeso molecular:508.612BioA-IN-1
CAS:<p>BioA-IN-1 (Compound 15) is an inhibitor of the key enzyme BioA in the biotin biosynthesis pathway of Mycobacterium tuberculosis, with an IC50 value of 0.195 μM. It exhibits antibacterial activity without cytotoxicity.</p>Fórmula:C18H17NO3SCor e Forma:SolidPeso molecular:327.397Pneumolysin-IN-1
CAS:<p>Pneumolysin-IN-1 (compound PB-3), characterized as a targeted small molecule inhibitor of Pneumolysin (PLY) with an IC50 value of 3.1 µM, acts as a pore-blocking agent and an anti-virulence factor. This compound is useful for researching infections caused by Streptococcus pneumoniae [1].</p>Fórmula:C23H16Cl2N2O4Cor e Forma:SolidPeso molecular:455.29Neuraminidase-IN-18
CAS:<p>Neuraminidase-IN-18 (compound N5), a novel polyheterocyclic neuraminidase (NA) inhibitor, demonstrates significant inhibitory activity against H5N1 NA, with an IC 50 of 0.14 μM against the wild-type H5N1 NA and 0.27 μM against the H5N1-H274Y mutant NA. This compound effectively binds to NAs, inhibiting influenza virus replication at the cellular level [1].</p>Fórmula:C22H18FN3O3SCor e Forma:SolidPeso molecular:423.46N-Cbz-L-Cysteine
CAS:<p>N-Cbz-L-Cysteine (Cbz-cysteine) (compound 5) functions as a potent inhibitor of β-lactamase II, exhibiting a K i value of 97 µM [1].</p>Fórmula:C11H13NO4SCor e Forma:SolidPeso molecular:255.29Uridine 3',5'-diphosphate
CAS:<p>Uridine 3′,5′-diphosphate (3′,5′-UDP; Compound pUp) serves as a competitive RNase inhibitor [1].</p>Fórmula:C9H14N2O12P2Cor e Forma:SolidPeso molecular:404.16SARS-CoV-2-IN-82
CAS:<p>SARS-CoV-2-IN-82 (compound A) acts as an inhibitor of the Programmed-1 ribosomal frameshift (-1 PRF) in SARS-CoV-2 [1].</p>Fórmula:C18H18N2Cor e Forma:SolidPeso molecular:262.35PolQi1
CAS:<p>PolQi1 is a highly efficient and selective Polϴ (DNA polymerase theta) inhibitor with an IC50 of 2 nM, showing potential for cancer therapy.</p>Fórmula:C18H14ClF5N4O2Pureza:98.97%Cor e Forma:SolidPeso molecular:448.77SHEN26
CAS:<p>SHEN26 (ATY014) is a potent, orally active RdRp inhibitor with an IC50 of 1.36 μM for SARS-CoV-2. As a 5'-cyclohexanecarboxylate derivative of GS-441524, SHEN26 inhibits viral nucleic acid synthesis, achieving antiviral effects. SHEN26 can be used for COVID-19 research [1] [2].</p>Fórmula:C19H23N5O5Cor e Forma:SolidPeso molecular:401.42DL-2-Aminopimelic Acid
CAS:<p>DL-2-Aminopimelic Acid acts as a weak agonist for glutamate receptors and also reduces the sensitivity of leech glutamate receptors to glutamate.</p>Fórmula:C7H13NO4Cor e Forma:SolidPeso molecular:175.18Antibacterial agent 169
CAS:<p>Antibacterial agent 169 (Compound 28), a pyrrolamide-type GyrB/ParE inhibitor, exhibits antibacterial properties by inhibiting Gyrase and Topo IV in Staphylococcus aureus. It has IC 50 values of 49 nmol/L and 1.513 μmol/L, respectively [1].</p>Fórmula:C19H25Cl2N5O3Cor e Forma:SolidPeso molecular:442.34MA220607
CAS:<p>MA220607 is an antibacterial agent characterized by low hemolytic toxicity and a dual-target mechanism of action (MOA). It promotes FtsZ protein polymerization, increases bacterial membrane permeability, and inhibits biofilm formation. The resistance rate of MA220607 is low, with MICs against Gram-positive bacteria and Gram-negative bacteria ranging from 0.062-2 μg/mL and 0.5-4 μg/mL, respectively [1].</p>Fórmula:C34H38INCor e Forma:SolidPeso molecular:587.58BDM91288
CAS:<p>BDM91288, an orally active AcrB efflux pump inhibitor of pyridinium piperazine, enhances the in vivo efficacy of levofloxacin in treating Klebsiella pneumoniae pulmonary infection in mouse models [1].</p>Fórmula:C17H22ClN5Cor e Forma:SolidPeso molecular:331.84PAV-104
CAS:<p>PAV-104 inhibits the replication of SARS-CoV-2 at a MOI of 0.01. It interacts with the SARS-CoV-2 nucleocapsid (N) and disrupts its oligomerization, thereby preventing particle assembly.</p>Fórmula:C29H35N5O6SCor e Forma:SolidPeso molecular:581.68NDM-1 inhibitor-5
CAS:<p>NDM-1 Inhibitor-5 (compound 57) exhibits strong inhibition of NDM-1, characterized by a K i of 2.5 μM. Additionally, it demonstrates synergistic antibacterial effects when combined with meropenem [1].</p>Fórmula:C24H23NO4Cor e Forma:SolidPeso molecular:389.44Isopyrazam
CAS:<p>Isopyrazam, a plant protection product, exhibits potent antifungal activity. When applied to crops, it effectively inhibits the growth of various plant pathogenic fungi, significantly enhancing both the yield and quality of the crops. This compound demonstrates exceptional disease resistance capabilities in agricultural applications.</p>Fórmula:C20H23F2N3OCor e Forma:SolidPeso molecular:359.41Benzisothiazolone
CAS:<p>Benzisothiazolone is an isothiazolinone fungicide that demonstrates growth inhibitory activity against Escherichia coli ATCC 8739 and yeast NCYC 1354. It is utilized in studies investigating growth inhibition models.</p>Fórmula:C7H5NOSCor e Forma:SolidPeso molecular:151.19PCNA-IN-1
CAS:<p>PCNA-IN-1 (Compound 11) is an inhibitor of the PCNA/PIP-box interaction, with an IC50 greater than 50 μM. It is applicable in cancer research.</p>Fórmula:C19H18I3NO3Cor e Forma:SolidPeso molecular:689.065MT0703
CAS:<p>MT0703 is a cephalosporin antibiotic featuring an aminothiazolylglycyl moiety with a 1,5-dihydroxy-4-pyridinone-2-carbonyl group, displaying potent activity against Pseudomonas species.</p>Fórmula:C26H25N7O9S3Cor e Forma:SolidPeso molecular:675.712'-Amino-2'-deoxyadenosine
CAS:<p>2'-Amino-2'-deoxyadenosine (9-(2-Amino-2-deoxypentofuranosyl)-9H-purin-6-amine) is a nucleoside antibiotic that effectively inhibits various Mycoplasma strains.</p>Fórmula:C10H14N6O3Peso molecular:266.26Glasmacinal
CAS:<p>Glasmacinal is a non-antibacterial macrolide compound with anti-inflammatory activities.</p>Fórmula:C37H62N2O10Cor e Forma:SolidPeso molecular:694.90A 76889
CAS:<p>A 76889 is an inhibitor of HIV-1 protease.</p>Fórmula:C44H58N8O6Pureza:98%Cor e Forma:SolidPeso molecular:794.98MBL-IN-5
CAS:<p>MBL-IN-5 is an inhibitor of metallo-β-lactamase (MBL). It effectively suppresses three clinically significant B1 subfamily MBLs: NDM-1, VIM-1, and IMP-1 with IC50 values of 0.05 nM, 14 nM, and 21 nM respectively. MBL-IN-5 notably enhances the efficacy of carbapenem antibiotics against MBL-producing clinical strains and, when combined with IPM antibiotics, significantly reduces bacterial load in a thigh infection model.</p>Fórmula:C20H16ClNO3Cor e Forma:SolidPeso molecular:353.80PLpro-IN-7
CAS:<p>PLpro-IN-7 (compound 83) is a novel papain-like protease (PLpro) inhibitor with an IC50 of 3 nM.</p>Fórmula:C30H34ClN7OCor e Forma:SolidPeso molecular:544.09ZINC4497834
CAS:<p>ZINC4497834 is an inhibitor of the main protease Mpro of SARS-CoV-2. It is utilized in research targeting the treatment of COVID-19.</p>Fórmula:C18H19N5O3SCor e Forma:SolidPeso molecular:385.44UNC0638 hydrate
CAS:<p>UNC0638 hydrate selectively inhibits G9a and GLP histone methyltransferases with IC50 values of 15 nM and 19 nM, respectively. It is effective in inhibiting invasion and migration of TNBC cells in vitro. Additionally, UNC0638 hydrate acts as an inhibitor of EHMT1/2 and induces the expression of fetal hemoglobin (HbF) in cultures of human erythroid progenitor cells. Furthermore, it exhibits antiviral activity against FMDV (foot-and-mouth disease virus) and VSV (vesicular stomatitis virus), demonstrating remarkable potency and selectivity across various epigenetic and non-epigenetic targets.</p>Fórmula:C30H49N5O3Cor e Forma:SolidPeso molecular:527.747-APRA
CAS:<p>7-APRA is a semisynthetic intermediate of the cephalosporin class of antibiotics. It exhibits antibacterial activity and is primarily used in the synthesis of other cephalosporin antibiotics, such as Cefaclor and Cefprozil.</p>Fórmula:C10H12N2O3SPeso molecular:240.28Griseofulvic Acid
CAS:<p>Griseofulvic Acid ((±)-Griseofulvic acid) is a metabolite of the antifungal agent Griseofulvin. It induces protein aggregation and tubulin polymerization in cell-free assays.</p>Fórmula:C16H15ClO6Peso molecular:338.74GC-78-HCl
CAS:<p>GC-78-HCl is an orally active, non-peptidic SARS-CoV-2 Mpro inhibitor with an enzyme IC50 of 0.19 μM. It exhibits strong anti-coronavirus activity and favorable pharmacokinetic properties.</p>Fórmula:C25H25Cl3N4O4Peso molecular:551.85Antibacterial agent 278
CAS:<p>Antibacterialagent 278 (compound B1) is an antimicrobial agent that exhibits potent inhibitory activity against Gram-positive bacteria.</p>Fórmula:C24H17ClF2N4O3Cor e Forma:SolidPeso molecular:482.87Nikkomycin Z
CAS:<p>Nikkomycin Z (Nikkomycin Z from Streptomyces tendae) is a competitive chitin synthase inhibitor.It inhibitor of the growth of filamentous fungi, insects,</p>Fórmula:C20H25N5O10Pureza:98%Cor e Forma:SolidPeso molecular:495.44SARS-CoV-2-IN-80
CAS:<p>SARS-CoV-2-IN-80 (compound 13), identified as a potent inhibitor of SARS-CoV-2 3CLpro, exhibits an IC50 value of 0.964 µM [1].</p>Fórmula:C16H10O2SCor e Forma:SolidPeso molecular:266.31LasR antagonist 1
CAS:<p>LasR antagonist 1 (Compound 7), with an IC50 of 0.4 μM, is an effective antagonist of LasR that modulates quorum sensing (QS) in the opportunistic pathogen Pseudomonas aeruginosa [1].</p>Fórmula:C20H15F3N2O3Cor e Forma:SolidPeso molecular:388.34TBAJ-5307
CAS:<p>TBAJ-5307 is a broad-spectrum anti-non-tuberculous mycobacteria inhibitor that targets the FO-domain of the engine, preventing rotation and proton-translocation. TBAJ-5307 inhibits non-tuberculous mycobacteria in vitro and in vivo [1].</p>Fórmula:C30H35BrN4O6Cor e Forma:SolidPeso molecular:627.53CTSL/CAPN1-IN-2
CAS:<p>CTSL/CAPN1-IN-2 (Compound 14b) serves as an orally active inhibitor targeting both CTSL and CAPN1, manifesting IC50 values of 6.88 nM for CTSL and 347.6 nM for CAPN1 respectively. This compound not only displays anti-inflammatory attributes but also features favorable pharmacokinetic properties. Moreover, CTSL/CAPN1-IN-2 shows extensive antiviral effects against coronaviruses by inhibiting viral entry [1].</p>Fórmula:C34H40N4O6Cor e Forma:SolidPeso molecular:600.7DHX9-IN-9
CAS:<p>DHX9-IN-9 (509) acts as an inhibitor of the RNA helicase DHX9, demonstrating an EC50 of 0.0177 μM in DHX9 cellular target engagement, primarily utilized in cancer research [1].</p>Fórmula:C21H21ClFN5O3S2Cor e Forma:SolidPeso molecular:510Vaniprevir
CAS:<p>Vaniprevir is a competitive HCV NS3/4A protease inhibitor, an antiviral(hepatitis C virus) drug that acts directly and blocks the viral replication process.</p>Fórmula:C38H55N5O9SPureza:97.41%Cor e Forma:SolidPeso molecular:757.94JTK-109
CAS:<p>JTK-109 is an inhibitor of hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitor and inhibits G1b and G3a subgenomic replicons and recombinant enzymes.</p>Fórmula:C37H33ClFN3O4Pureza:98.48% - 99.68%Cor e Forma:SolidPeso molecular:638.13Eravacycline dihydrochloride
CAS:<p>Eravacycline dihydrochloride (TP-434-046) is a potent and broad-spectrum antibacterial agent against six E. coli (MICs: 0.125-0.25 mg/L).</p>Fórmula:C27H33Cl2FN4O8Pureza:94.59% - 95%Cor e Forma:SolidPeso molecular:631.48Rupintrivir
CAS:<p>Rupintrivirvr (AG7088) is a mimetic peptide inhibitor of rhinovirus (HRV) 3C cysteine protease with antiviral activity for the study of viral infections.</p>Fórmula:C31H39FN4O7Pureza:97.72% - 99.35%Cor e Forma:SolidPeso molecular:598.66D75-4590
CAS:<p>D75-4590, a β-1,6-Glucan synthetase inhibitor, combats fungal infections by targeting cell walls.</p>Fórmula:C21H27N5Pureza:98.56% - 98.85%Cor e Forma:SolidPeso molecular:349.47IDX184
CAS:<p>IDX184 is a potent, orally active, targeted HCV polymerase inhibitor and nucleoside polymerase.IDX184 effectively inhibits HCV polymerase (IC50=0.31 μM, Ki=52.3</p>Fórmula:C25H35N6O9PSPureza:97.15%Cor e Forma:SolidPeso molecular:626.62Cap-dependent endonuclease-IN-1
CAS:<p>Cap-dependent endonuclease-IN-1: potent, oral inhibitor with antiviral properties against influenza.</p>Fórmula:C27H22F2N2O6SPureza:98.88% - 99.09%Cor e Forma:SolidPeso molecular:540.54CCF0058981
CAS:<p>CCF0058981: noncovalent inhibitor for SARS-CoV-2 & -1 proteases; IC50s: 68 nM (SC2) & 19 nM (SC1). Potential COVID-19 research use.</p>Fórmula:C24H19ClN6OPureza:98.94%Cor e Forma:SoildPeso molecular:442.9CTPS1-IN-1
CAS:<p>CTPS1-IN-1 is a cytidine-5′ triphosphate synthase 1 (CTPS1) inhibitor with potential antitumor activity and can be used to study autoimmune diseases.</p>Fórmula:C21H22N6O4S2Pureza:99.46%Cor e Forma:SolidPeso molecular:486.57LeuRS-IN-1 hydrochloride
CAS:<p>LeuRS-IN-1 hydrochloride is a Mycobacterium tuberculosis leucyl-tRNA synthetase inhibitor with antileukemic activity and antimalarial activity.</p>Fórmula:C10H14BCl2NO3Pureza:97.34% - 99.61%Cor e Forma:SolidPeso molecular:277.94Tigemonam
CAS:<p>Tigemonam is a monobactam, a novel orally administered monobactam that protects against gram-negative aerobic bacterial pathogens. Cost-effective and quality-assured.</p>Fórmula:C12H15N5O9S2Pureza:99.03% - >99.99%Cor e Forma:SolidPeso molecular:437.41HRO761
CAS:<p>HRO761 is a potent Werne r syndrome RecQ DNA deconjugase (WRN) inhibitor that can be used to study cancers such as colon and stomach cancer.</p>Fórmula:C31H31ClF3N9O5Pureza:98.74% - 99.62%Cor e Forma:SolidPeso molecular:702.08FGI-106 tetrahydrochloride
CAS:<p>FGI-106 tetrahydrochloride demonstrates potent inhibitory activity across a broad spectrum of viruses, including those causing hemorrhagic fevers such as Ebola</p>Fórmula:C28H42Cl4N6Pureza:99.68%Cor e Forma:SolidPeso molecular:604.48Durlobactam sodium salt
CAS:<p>Durlobactam sodium salt (ETX2514) have an IC50 values of 4, 14 and 190 nM against class A KPC-2, class C AmpC and class D OXA-24.Cost-effective and quality-assured.</p>Fórmula:C8H10N3NaO6SPureza:97.01% - 99.03%Cor e Forma:SolidPeso molecular:299.23SR 11302
CAS:<p>SR 11302 is an inhibitor of activator protein-1 (AP-1).</p>Fórmula:C26H32O2Pureza:98.65%Cor e Forma:SolidPeso molecular:376.53L-Eflornithine monohydrochloride
CAS:<p>L-Eflornithine is an irreversible ornithine decarboxylase (ODC) inhibitor with a KD of 1.3±0.3 µM, and a Kinact of 0.15±0.03 min-1. L-Eflornithine monohydrochloride (L-DFMO monohydrochloride) is an enantiomer of Eflornithine.</p>Fórmula:C6H13ClF2N2O2Cor e Forma:SolidPeso molecular:218.63Reutericyclin
CAS:<p>Reutericyclin is a unique tetramic acid, is an antibiotic produced by some strains of Lactobacillus reuteri.</p>Fórmula:C20H31NO4Pureza:98%Cor e Forma:SolidPeso molecular:349.46Haloxon
CAS:<p>Haloxon is an organophosphorus anthelmintic. Haloxon is used against nematodes of the abomasum and small intestine in ruminants.</p>Fórmula:C14H14Cl3O6PCor e Forma:SolidPeso molecular:415.59α-Terpineol
CAS:<p>Terpineol possesses antifungal activity against Trichophyton mentagrophytes, it also exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria. α-Terpineol (Terpineol) shows anticonvulsant, and anti-inflammatory activities, it inhibits the gene expression of the IL-6 receptor.</p>Fórmula:C10H18OPureza:97.55%Cor e Forma:Colorless LiquidPeso molecular:154.252'-Hydroxy-4'-methylacetophenone
CAS:<p>2'-Hydroxy-4'-methylacetophenone, a phenolic compound isolated from Angelicae koreana roots possesses acaricidal property. 2'-Hydroxy-4'-methylacetophenone has acaricidal activity, it could be used in the preparation of 4'-methyl-2'-[(p-tolylsulfonyl) oxy] acetophenone.</p>Fórmula:C9H10O2Pureza:99.88%Cor e Forma:Black LiquidPeso molecular:150.17Ulifloxacin
CAS:<p>Ulifloxacin is a useful organic compound for research related to life sciences. The catalog number is T65577 and the CAS number is 112984-60-8.</p>Fórmula:C16H16FN3O3SCor e Forma:SolidPeso molecular:349.38Policresulen
CAS:<p>Policresulen is a useful organic compound for research related to life sciences. The catalog number is T66902 and the CAS number is 101418-00-2.</p>Fórmula:C8H10O5SCor e Forma:SolidPeso molecular:218.22Phosalacine
CAS:<p>Phosalacine, isolated from Kitasatosporia phosalacinea, is a new herbicidal antibiotic that contains phosphinothricin.</p>Fórmula:C14H28N3O6PPureza:98%Cor e Forma:SolidPeso molecular:365.3672-Mercaptopyridine N-oxide sodium
CAS:<p>2-Mercaptopyridine N-oxide sodium is a useful organic compound for research related to life sciences. The catalog number is T66776 and the CAS number is 3811-73-2.</p>Fórmula:C5H4NNaOSCor e Forma:SolidPeso molecular:149.14N-Butylthiophosphoric triamide
CAS:<p>N-Butylthiophosphoric triamide is a useful organic compound for research related to life sciences. The catalog number is T65336 and the CAS number is 94317-64-3.</p>Fórmula:C4H14N3PSCor e Forma:SolidPeso molecular:167.21Lenampicillin hydrochloride
CAS:<p>Lenampicillin hydrochloride is an orally active prodrug of Ampicillin. Lenampicillin hydrochloride is an effective beta-lactam antibacterial agent that inhibits bacterial penicillin-binding proteins. It is applied in the investigation of suppurative skin </p>Fórmula:C21H24ClN3O7SPureza:98%Cor e Forma:SolidPeso molecular:497.95Antiviral agent 5
CAS:<p>Antiviral agent 5 is a crucial intermediate utilized in the development of antiviral agents that specifically target 3C and 3CL proteases, which includes the SARS-CoV-2 M pro enzyme.</p>Fórmula:C18H30N2O7Cor e Forma:SolidPeso molecular:386.445CRS3123 dihydrochloride
CAS:<p>CRS3123 (REP-3123) dihydrochloride is an orally active, fully synthetic antimicrobial agent that effectively inhibits Clostridioides difficile methionyl-tRNA synthetase (MetRS). CRS3123 dihydrochloride can be used in the study of Clostridioides difficile infection (CDI).</p>Fórmula:C19H21Br2Cl2N3O2SCor e Forma:SolidPeso molecular:586.165'-DMT-3'-TBDMS-ibu-rG
CAS:<p>5'-DMT-3'-TBDMS-ibu-rG is a modified nucleoside employed in deoxyribonucleic acid (DNA) synthesis.</p>Fórmula:C41H51N5O8SiCor e Forma:SolidPeso molecular:769.96Erythromycylamine
CAS:<p>Erythromycylamine is a useful organic compound for research related to life sciences. The catalog number is T64443 and the CAS number is 26116-56-3.</p>Fórmula:C37H70N2O12Cor e Forma:SolidPeso molecular:734.969A 53868A
CAS:<p>A 53868A is an antibiotic, it is isolated from Streptomyces luridus.</p>Fórmula:C11H22N3O5PPureza:98%Cor e Forma:SolidPeso molecular:307.287Tetraconazole
CAS:<p>Tetraconazole is an agent of pesticides.</p>Fórmula:C13H11Cl2F4N3OCor e Forma:Liquid ViscousPeso molecular:372.14Ethynylcytidine
CAS:<p>Ethynylcytidine is a nucleoside antimetabolite.</p>Fórmula:C11H13N3O5Pureza:98%Cor e Forma:SolidPeso molecular:267.24l-Atabrine dihydrochloride
CAS:<p>l-Atabrine dihydrochloride displays antiprion activity. l-Atabrine dihydrochloride is a less active enantiomer of quinacrine.</p>Fórmula:C23H31Cl2N3OPureza:98%Cor e Forma:SolidPeso molecular:436.42Oleandomycin
CAS:<p>Oleandomycin, a macrolide antibiotic structurally similar to Erythromycin, exhibits antimicrobial activity.</p>Fórmula:C35H61NO12Pureza:98%Cor e Forma:White Amorphous Powder SolidPeso molecular:687.86PqsR/LasR-IN-1
CAS:<p>PqsR/LasR-IN-1 (Compound 2a) is a potent inhibitor of LasR and PqsR systems in P. aeruginosa. PqsR/LasR-IN-1 is also a inhibitor of hERG (IC50= 6.77 μM).</p>Fórmula:C24H20ClNO3Cor e Forma:SolidPeso molecular:405.87Stearyl gallate
CAS:<p>Stearyl gallate is a useful organic compound for research related to life sciences. The catalog number is T65655 and the CAS number is 10361-12-3.</p>Fórmula:C25H42O5Cor e Forma:SolidPeso molecular:422.606Pulcherriminic acid
CAS:<p>Pulcherriminic acid, a cyclic dipeptide, chelates Fe3+, forms pulcherrimin, and has antimicrobial properties used in food, agriculture, and medicine.</p>Fórmula:C12H20N2O4Cor e Forma:SolidPeso molecular:256.30Pseudomonic acid C
CAS:<p>Pseudomonic acid C is the analogue of Pseudomonic Acid D which is an antibiotic agent from Pseudomonas fluorescens.</p>Fórmula:C26H44O8Pureza:98%Cor e Forma:SolidPeso molecular:484.62Ramifenazone
CAS:<p>Ramifenazone is a drug of nonsteroidal anti-inflammatory.</p>Fórmula:C14H19N3OPureza:98%Cor e Forma:SolidPeso molecular:245.32
