Microbiologia/Virologia
Os inibidores de microbiologia e virologia são compostos que têm como alvo microrganismos, incluindo bactérias, vírus e fungos, interrompendo seu crescimento, replicação ou sobrevivência. Esses inibidores são essenciais para estudar a patogênese microbiana, entender os mecanismos de resistência e desenvolver novas terapias antimicrobianas e antivirais. Os inibidores nessa categoria são usados para combater doenças infecciosas, explorar a ecologia microbiana e investigar as interações hospedeiro-patógeno. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para microbiologia e virologia para apoiar sua pesquisa em doenças infecciosas, microbiologia e virologia.
Subcategorias de "Microbiologia/Virologia"
- Antibacteriano(3.153 produtos)
- Antibiótico(932 produtos)
- Antifecção(24 produtos)
- DHFR(34 produtos)
- Síntese de DNA/RNA(774 produtos)
- HBV(182 produtos)
- HIV Protease(477 produtos)
- HSV(94 produtos)
- Integrase(2 produtos)
- Ribossomo(13 produtos)
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Foram encontrados 6158 produtos de "Microbiologia/Virologia"
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ZINC4497834
CAS:ZINC4497834 is an inhibitor of the main protease Mpro of SARS-CoV-2. It is utilized in research targeting the treatment of COVID-19.Fórmula:C18H19N5O3SCor e Forma:SolidPeso molecular:385.44PLpro-IN-7
CAS:PLpro-IN-7 (compound 83) is a novel papain-like protease (PLpro) inhibitor with an IC50 of 3 nM.Fórmula:C30H34ClN7OCor e Forma:SolidPeso molecular:544.0920S Proteasome-IN-4
CAS:<p>20S Proteasome-IN-4: brain-penetrant, parasite-specific, oral, inhibits T.b. brucei proteasome (IC50: 6.3nM), for HAT research.</p>Fórmula:C20H18ClF2N3O3Cor e Forma:SolidPeso molecular:421.83iPAF1C
CAS:<p>iPAF1C is a powerful inhibitor of the polymerase-associated factor 1 complex (PAF1C) and exhibits anti-HIV activity [1].</p>Fórmula:C27H26BrFN4OCor e Forma:SolidPeso molecular:521.42HIV-1 inhibitor-61
CAS:HIV-1 Inhibitor-61 (2c) serves as a potent inhibitor of HIV-1 reverse transcriptase, exhibiting an EC50 value of 0.07 nM in NL4-3 wt MT-4 cells [1].Fórmula:C24H24F2N2O2SCor e Forma:SolidPeso molecular:442.52LasR-IN-2
LasR-IN-2 blocks LasR via H-bond with TRY-56, useful in bacterial infection and CF research.Fórmula:C21H16ClN3O2Cor e Forma:SolidPeso molecular:377.82RdRP-IN-5
CAS:<p>RdRP-IN-5 (compound 20), a potent inhibitor of the influenza virus RNA-dependent RNA polymerase (RdRP), has potential application in influenza research [1].</p>Fórmula:C23H21N3O5Pureza:98%Cor e Forma:SolidPeso molecular:419.43AN-12-H5
CAS:AN-12-H5 is an anti-enteroviral compound that targets the replication process of PV and EV71 viruses.Fórmula:C24H23N3O4S3Cor e Forma:SolidPeso molecular:513.65Adafosbuvir
CAS:<p>Adafosbuvir has antiviral activity.</p>Fórmula:C22H29FN3O10PCor e Forma:SolidPeso molecular:545.457Cap-dependent endonuclease-IN-6
CAS:Cap-dependent endonuclease-IN-6 (compound 13) is a Cap-dependent endonuclease (CEN) inhibitor that inhibits influenza virus.Fórmula:C23H21N3O3SCor e Forma:SolidPeso molecular:419.5PptT-IN-2
PptT-IN-2 inhibits PptT enzyme crucial in tuberculosis, with 2.5 μM IC50, showing potential in TB research.Fórmula:C22H29N5O2Cor e Forma:SolidPeso molecular:395.5HRSV/HMPV-IN-1
CAS:HRSV/HMPV-IN-1 (compound 3) is an inhibitor targeting HRSV/HMPV, exhibiting EC50 values of < 0.2 μM against human RSV-A and < 0.5 μM for human MPV A2 TN/94-49. This compound is utilized in the study of bronchiolitis and pneumonia.Fórmula:C34H31ClF2N4O5SCor e Forma:SolidPeso molecular:681.15Chitin synthase inhibitor 5
Calpain Inhibitor-2, lipophilic, inhibits calpain; shows anti-proliferative effects on melanoma, PC-3 cells; blocks 80% DU-145 cell invasion.Fórmula:C23H22BrN3O5Cor e Forma:SolidPeso molecular:500.34Beclabuvir
CAS:Beclabuvir blocks HCV NS5B polymerase at thumb site 1, effective on genotypes 1, 3, 4, 5 with IC50 <28 nM.Fórmula:C36H45N5O5SPureza:99.87% - 99.93%Cor e Forma:SolidPeso molecular:659.84NS2B/NS3-IN-2
<p>Potent dengue inhibitor NS2B/NS3-IN-2 (IC50: 6 nM, Ki: 0.66 μM) boosts cell viability, non-toxic.</p>Fórmula:C24H21N3O5SCor e Forma:SolidPeso molecular:463.51EFdA-TP tetrasodium
CAS:EFdA-TP tetrasodium is a potent HIV-1 inhibitor that blocks DNA synthesis as an ICT or DCT.Fórmula:C12H11FN5Na4O12P3Pureza:98%Cor e Forma:SolidPeso molecular:621.12(S)-Batylalcohol
CAS:<p>(S)-Batylalcohol (1-O-Octadecyl-sn-glycerol) is an analogue of phosphonoformic acid (PFA) and demonstrates higher in vitro antiviral activity against human immunodeficiency virus type 1 (HIV-1) compared to PFA. This compound is applicable in antiretroviral research.</p>Fórmula:C21H44O3Cor e Forma:SolidPeso molecular:344.572Antifungal agent 113
CAS:Antifungalagent 113 (compound 9a) serves as an effective antifungal and antibacterial agent. It exhibits strong inhibitory activity against both S. aureus and methicillin-resistant S. aureus.Fórmula:C23H20O5Cor e Forma:SolidPeso molecular:376.40SARS-CoV-2-IN-102
CAS:SARS-CoV-2-IN-102 (example 58) is an inhibitor of the SARS-CoV papain-like protease (SARS-CoVPLpro), demonstrating an IC50 of less than 100 nM.Fórmula:C29H34F2N6O2Cor e Forma:SolidPeso molecular:536.62Werner syndrome RecQ helicase-IN-2
CAS:Werner syndrome RecQ helicase-IN-2 is a potent Werner syndrome RecQ DNA helicase (WRN) inhibitor, useful in research on colorectal and gastric cancers.Fórmula:C32H34F3N9O5Pureza:99.02%Cor e Forma:SolidPeso molecular:681.67Menoctone
CAS:Menoctone is an orally effective antimalarial agent that inhibits blood-induced rodent malaria. It enhances the antimalarial effects of chloroquine or quinine, making it useful for malaria research.Fórmula:C24H32O3Cor e Forma:SolidPeso molecular:368.51Antitumor agent-75
Antitumor agent-75 is a novel and potent antitumor agent.Fórmula:C26H23FN6Cor e Forma:SolidPeso molecular:438.5Gougerotin
CAS:Gougerotin is an inhibitor of protein synthesis.Fórmula:C16H25N7O8Cor e Forma:SolidPeso molecular:443.41(±)-Tuaimenal A
CAS:(±)-Tuaimenal A ((+)-1) is a secondary metabolite and a derivative of Sesamol. It exhibits potent inhibitory activity against SARS-CoV-2 3CLpro, with an IC50 of 33.3 μM. (±)-Tuaimenal A is applicable in research related to SARS-CoV-2 infection.Fórmula:C23H30O4Cor e Forma:SolidPeso molecular:370.48Ceftolozane TFA
CAS:<p>Ceftolozane TFA is a cephalosporin class antibiotic (antibiotic) designed to inhibit Gram-negative bacterial infections. Additionally, it can be utilized in the synthesis of novel antibiotics (antibiotic) that are more efficacious and safer.</p>Fórmula:C25H31F3N12O10S2Cor e Forma:SolidPeso molecular:780.71DRF-8417
CAS:<p>DRF-8417 is an oxazolidinone antibiotic, active against both Gram-positive bacteria and fastidious Gram-negative bacteria. The MIC50 and MIC90 values of DRF-8417 for Gram-positive pathogens range between 0.06-1 mg/L.</p>Fórmula:C15H17N3O5SCor e Forma:SolidPeso molecular:351.38TAN-1057C
CAS:TAN-1057C is a potent antibiotic with antimicrobial activity against both Gram-negative and Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus (MRSA).Fórmula:C13H25N9O3Cor e Forma:SolidPeso molecular:355.4PfCLK3-IN-1
<p>PfCLK3-IN-1 (Compound 4) serves as a covalent inhibitor of the malaria parasite CLK3 (Pf CLK3) under alkaline conditions, with a pEC50 of 7.1. It inhibits the maturation of gametocytes during the sexual stage of the parasite, thereby hindering transmission. Additionally, PfCLK3-IN-1 effectively suppresses the Dd2-B2 clone of the malaria parasite, exhibiting an IC50 of 239.5 nM.</p>Fórmula:C28H27ClN4O4Cor e Forma:SolidPeso molecular:518.99CCC-0975
CAS:CCC-0975 is an inhibitor of hepatitis B virus (HBV) with an EC50 of 10 μM. It interferes with the conversion of relaxed circular DNA (rcDNA) to covalently closed circular DNA (cccDNA) and reduces cccDNA and its precursor deproteinized rcDNA (DP-rcDNA), without promoting their degradation inside cells. CCC-0975 holds potential for chronic hepatitis B research.Fórmula:C21H17ClF3N3O3SCor e Forma:SolidPeso molecular:483.89MtDTBS-IN-1
MtDTBS-IN-1 is a notably potent binder (K_D = 57 nM) and inhibitor (K_i = 5 μM) of MtDTBS.Fórmula:C16H16N4O5Cor e Forma:SolidPeso molecular:344.32Ibafloxacine
CAS:Ibafloxacine (R835) is a fluoroquinolone antibiotic that is used exclusively in veterinary applications and shows zero good bacteriostatic effect againstFórmula:C15H14FNO3Pureza:97.67%Cor e Forma:SolidPeso molecular:275.27MB076
CAS:MB076 is an innovative heterocyclic triazole designed with enhanced plasma stability. It effectively inhibits seven distinct Class C Acinetobacter-derived cephalosporinases (ADCs) β-lactamase variants with K i values less than 1 μM. Additionally, MB076 demonstrates a synergistic effect when combined with various cephalosporins to restore pBCSK(−) susceptibility [1].Fórmula:C9H12BN7O5S2Peso molecular:373.185-Methylcytosine hydrochloride
CAS:5-Methylcytosine hydrochloride plays a critical role in regulating gene expression, promoting genomic imprinting, and inhibiting transposon factors. It is also closely associated with translation fidelity and tRNA recognition.Fórmula:C5H8ClN3OCor e Forma:SolidPeso molecular:161.59MK-8876
CAS:MK-8876 is an Inhibitor of HCV NS5B Site D.Fórmula:C32H24F2N4O5SPureza:98%Cor e Forma:SolidPeso molecular:614.62Pyriftalid
CAS:Pyriftalid is a novel insecticide known for its potent inhibitory activity against a variety of pests. It is widely utilized in agriculture to effectively manage crop pests, thereby enhancing both the yield and quality of crops. Additionally, research is exploring the use of Pyriftalid in boosting plant resistance to pests and diseases.Fórmula:C15H14N2O4SCor e Forma:SolidPeso molecular:318.35SARS-CoV-2-IN-99
CAS:<p>SARS-CoV-2-IN-99 (compound 58) is an inhibitor of the main protease of SARS-CoV-2.</p>Fórmula:C20H16Br2NO4PCor e Forma:SolidPeso molecular:525.13GR 122222X
CAS:GR 122222X is an inhibitor of topoisomerase II.Fórmula:C26H35N5O11SPureza:98%Cor e Forma:SolidPeso molecular:625.65Cefempidone
CAS:Cefempidone (GR 50692) is a third-generation cephalosporin antibiotic. It exhibits antibacterial activity by inhibiting penicillin-binding proteins involved in the synthesis of bacterial cell walls.Fórmula:C22H21N7O6S2Peso molecular:543.58Nikkomycin Z
CAS:Nikkomycin Z (Nikkomycin Z from Streptomyces tendae) is a competitive chitin synthase inhibitor.It inhibitor of the growth of filamentous fungi, insects,Fórmula:C20H25N5O10Pureza:98%Cor e Forma:SolidPeso molecular:495.44WRN inhibitor 7
CAS:<p>WRN inhibitor 7 (Compound h6), a potent inhibitor of Werner syndrome helicase, demonstrates effective suppression of WRN's helicase and ATPase activities with IC50 values of 9.8 μM and 15.8 μM, respectively. This compound is utilized in the study of microsatellite instable (MSI) cancers [1].</p>Fórmula:C27H23N3O6Cor e Forma:SolidPeso molecular:485.49LasR antagonist 1
CAS:LasR antagonist 1 (Compound 7), with an IC50 of 0.4 μM, is an effective antagonist of LasR that modulates quorum sensing (QS) in the opportunistic pathogen Pseudomonas aeruginosa [1].Fórmula:C20H15F3N2O3Cor e Forma:SolidPeso molecular:388.34TBAJ-5307
CAS:TBAJ-5307 is a broad-spectrum anti-non-tuberculous mycobacteria inhibitor that targets the FO-domain of the engine, preventing rotation and proton-translocation. TBAJ-5307 inhibits non-tuberculous mycobacteria in vitro and in vivo [1].Fórmula:C30H35BrN4O6Cor e Forma:SolidPeso molecular:627.53Antibacterial agent 204
CAS:<p>Antibacterial agent 204 (Compd P2-56-3) enhances the activity of Rifampin (RIF) against Acinetobacter baumannii and Klebsiella pneumoniae by disrupting the outer membrane of A. baumannii. T [1].</p>Fórmula:C14H18N2Cor e Forma:SolidPeso molecular:214.31Uridine 3',5'-diphosphate
CAS:<p>Uridine 3′,5′-diphosphate (3′,5′-UDP; Compound pUp) serves as a competitive RNase inhibitor [1].</p>Fórmula:C9H14N2O12P2Cor e Forma:SolidPeso molecular:404.16NDM-1 inhibitor-5
CAS:NDM-1 Inhibitor-5 (compound 57) exhibits strong inhibition of NDM-1, characterized by a K i of 2.5 μM. Additionally, it demonstrates synergistic antibacterial effects when combined with meropenem [1].Fórmula:C24H23NO4Cor e Forma:SolidPeso molecular:389.44VV261
CAS:<p>VV261 is an orally active inhibitor of the Influenza Virus. It exhibits activity against the Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV) and the Lymphocytic Choriomeningitis Virus (LCMV), with EC50 values of 0.89 and 0.15, respectively.</p>Fórmula:C28H34FN3O11Cor e Forma:SolidPeso molecular:607.58BPR3P0128
CAS:BPR3P0128, a non-nucleoside RNA-dependent RNA polymerase (RdRp) inhibitor, is effective orally and can inhibit various SARS-CoV-2 variants. It exhibits EC 50 values of 0.62 µM for SARS-CoV-2 and 0.14 µM for HCoV-229E, demonstrating potent anti-pancoronavirus activity at submicromolar concentrations. Additionally, BPR3P0128 displays synergistic antiviral effects when used in combination with Remdesivir [1].Fórmula:C22H18BrN3O2Cor e Forma:SolidPeso molecular:436.30InhA-IN-7
CAS:<p>InhA-IN-7 (Compound 11), a derivative of Triclocan, shows inhibitory activity against enoyl-acyl carrier protein reductase (InhA) with an IC50 of 96 nM. It effectively inhibits the proliferation of both wildtype and mutant strains of Mycobacterium tuberculosis, exhibiting minimum inhibitory concentrations (MICs) ranging from 19 to 75 μM [1].</p>Fórmula:C17H18Cl2O2Cor e Forma:SolidPeso molecular:325.23JPL
CAS:JPL is an InhA-cofactor-ligand 3FNG inhibitor and is used for the study of tuberculosis [1].Fórmula:C19H20Cl2O2Cor e Forma:SolidPeso molecular:351.27Elongation factor P-IN-2
Elongation factor P-IN-2, a β-lysine derivative, is a potent EFP inhibitor reducing E. coli growth.Fórmula:C16H35N3O2Cor e Forma:SolidPeso molecular:301.47DENV-IN-6
CAS:<p>DENV-IN-6, a potent anti-DENV (I-IV) and HIV-1 IIIB inhibitor with EC50 ranging 6.8-17.5 μM for DENV and EC50 0.0181 μM for HIV-1.</p>Fórmula:C23H26ClFN4OSCor e Forma:SolidPeso molecular:461HIV-1 inhibitor-8
HIV-1 inhibitor-8: potent oral NNRTI, low toxicity, IC50: 0.081 μM, effective on multiple strains, EC50: 4.44-54.5 nM.Fórmula:C25H21N5OSCor e Forma:SolidPeso molecular:439.53Glutamate-5-kinase-IN-2
Glutamate-5-kinase-IN-2 (compound 54) is a potent G5K inhibitor with 4.2 μM MIC, potential in anti-TB research.Fórmula:C17H10ClFN2Cor e Forma:SolidPeso molecular:296.73Pol I-IN-1
Pol I-IN-1 is a powerful inhibitor of RNA polymerase I (Pol I), specifically targeting the large catalytic subunit RPA194, demonstrating an inhibitionFórmula:C23H22N4O2Cor e Forma:SolidPeso molecular:386.45TCMDC-136230
TCMDC-136230 is a novel inhibitor of Plasmodium calcium kinetics with minimal inhibition of haemoglobin crystallisation.Fórmula:C24H34N4O2SCor e Forma:SolidPeso molecular:442.62SARS-CoV-2 nsp14-IN-2
<p>SARS-CoV-2 nsp14-IN-2: Strong Nsp14 methyltransferase inhibitor (IC50: 0.09 μM), potential for COVID-19 research.</p>Fórmula:C21H21N5O5SCor e Forma:SolidPeso molecular:455.49Antibacterial agent 118
Antibacterial agent 118, potent against various mycobacteria, has MIC values ranging from 10.2 to 163.0 μM. Useful in TB research.Fórmula:C19H21N5O2SCor e Forma:SolidPeso molecular:383.47LpxC-IN-10
CAS:LpxC-IN-10 is a selective LpxC inhibitor with an MIC of 0.5 μg/mL against E. coli and K. pneumoniae and is capable of being used to study bacterial infections.Fórmula:C30H31N5O3Cor e Forma:SolidPeso molecular:509.6Antitubercular agent-16
Compound 5q is a potent antitubercular with low MIC90 values (0.40-23.51 μg/mL) against M. tuberculosis strains, showing minimal cytotoxicity.Fórmula:C21H27N3SCor e Forma:SolidPeso molecular:353.52HBV-IN-31
CAS:HBV-IN-31: strong cccDNA inhibitor, anti-HBV, IC50=0.13 µM HBsAg, hampers cell growth.Fórmula:C23H18ClNO6Cor e Forma:SolidPeso molecular:439.85Acetomycin
CAS:<p>Acetomycin, a γ-lactone from S. ramulosus, halts HCT-8 colon and L1210 leukemia cell growth.</p>Fórmula:C10H14O5Cor e Forma:SolidPeso molecular:214.22SP inhibitor 1
<p>SP inhibitor 1 blocks SARS-CoV-2 replication in vitro (0.3250<5.98 μM) and targets SP protein (IC50: 3.26 μM) with antiviral effects.</p>Fórmula:C36H38N2O2Cor e Forma:SolidPeso molecular:530.7LasR-IN-3
LasR-IN-3 inhibits LasR in Pseudomonas, disrupting its dimer, causing loss of function.Fórmula:C22H19N3O2Cor e Forma:SolidPeso molecular:357.41bc1 Complex-IN-1
CAS:Bc1 Complex-IN-1 (compound 12g) is a potent inhibitor of the bc1 complex, demonstrating fungicidal properties against cucumber downy mildew (CDM).Fórmula:C16H22N6O5S2Cor e Forma:SolidPeso molecular:442.513Lavendomycin
CAS:Lavendomycin can be extracted from Streptomyces lavendulae and has active against Gram-positive bacteria.Fórmula:C29H50N10O8Cor e Forma:SolidPeso molecular:666.77Fenbenicillin potassium
CAS:<p>Fenbenicillin (Phenbenicillin) potassium is a semi-synthetic penicillin with antibacterial spectrum activity.</p>Fórmula:C22H22KN2O5SCor e Forma:SolidPeso molecular:465.584Imidocarb dihydrochloride monohydrate
Imidocarb dihydrochloride monohydrate is an effective antiprotozoal agent against the parasite B. bovis (IC50: 87 μg/ml).Fórmula:C19H24Cl2N6O2Cor e Forma:SolidPeso molecular:439.34TLR8 agonist 4
<p>TLR8 agonist 4 inhibits wild-type and lamivudine/entecavir-resistant HBV; IC50: 0.15 μM and 0.10 μM.</p>Fórmula:C28H27N5O5SCor e Forma:SolidPeso molecular:545.61Methyl piperazine-2-carboxylate
CAS:Methyl piperazine-2-carboxylate (compound 4) is a potent activator of METTL3/METTL14/WTAP. It enhances the production of HIV-1p24 viral particles and increases the level of N6-methyladenosine in the viral RNA genome.Fórmula:C6H12N2O2Cor e Forma:SolidPeso molecular:144.172HBV-IN-11
CAS:HBV-IN-11 is a potent inhibitor of HBsAg secretion (EC50: 0.46 μM).Fórmula:C21H24ClNO6Cor e Forma:SolidPeso molecular:421.87BM635 hydrochloride
<p>BM635 hydrochloride, an MmpL3 inhibitor, strongly blocks Divergent bacteriophage H37Rv (MIC50: 0.08 μM), with doubled in vivo potency.</p>Fórmula:C25H30ClFN2OCor e Forma:SolidPeso molecular:428.97Fabimycin
CAS:Fabimycin, a FabI inhibitor, combats drug-resistant gram-negative bacterial infections effectively.Fórmula:C23H25ClN4O3Cor e Forma:SolidPeso molecular:440.92Anti-Influenza agent 3
Compound 11h: Potent, low-toxicity anti-influenza, inhibits M2 ion channels. EC50: 3.29μM (H3N2), 2.45μM (H1N1).Fórmula:C16H22ClNOSCor e Forma:SolidPeso molecular:311.87BRD-K98645985
CAS:BRD-K98645985: BAF inhibitor, binds ARID1A, reverses HIV-1 latency, EC50 ~2.37μM, alters nucleosome placement.Fórmula:C33H43N5O4Pureza:98%Cor e Forma:SolidPeso molecular:573.73Antifungal agent 127
CAS:<p>Antifungalagent 127 (Compound 6c) is an antifungal agent with potent inhibitory activity against Botrytis cinerea and Rhizoctonia solani.</p>Fórmula:C13H12ClN3OCor e Forma:SolidPeso molecular:261.707XR8-89
CAS:XR8-89, a potent PLpro inhibitor (IC50=0.1μM), blocks SARS-CoV-2 replication; useful for research.Fórmula:C29H36N4O2SCor e Forma:SolidPeso molecular:504.69BMIM-TFSI
CAS:<p>BMIM-TFSI (compound8) is an HIV-1 integrase inhibitor that effectively suppresses both the 3'-processing (3'-P) and strand transfer (ST) steps of the integration process. It is applicable in HIV-1 research.</p>Fórmula:C10H15F6N3O4S2Cor e Forma:SolidPeso molecular:419.364MsbA-IN-4
<p>MsbA-IN-4 (Compound 32) is a highly selective and potent inhibitor of MsbA (IC50: 3 nM).MsbA-IN-4 inhibits Escherichia coli (MIC: 12 μM).</p>Fórmula:C23H18Cl2FN5OCor e Forma:SolidPeso molecular:470.33Antibacterial agent 81
CAS:Antibacterial agent 81 blocks DNA transcription, targets S. aureus (MIC 12.5μM) & M. smegmatis (MIC 7.8μM). Used in infection research.Fórmula:C33H28N2O8Cor e Forma:SolidPeso molecular:580.58BMS-818251
CAS:BMS-818251 is a potent small-molecule inhibitor that targets HIV-1 entry, with an EC50 value of 0.019 nM. It exhibits over 10 times greater efficacy on the cross-subtype panels of the 208-HIV-1 strain compared to BMS-626529. BMS-818251 enhances potency through interactions with gp120 residues in the conserved β20-β21 hairpin.Fórmula:C29H26N6O5SCor e Forma:SolidPeso molecular:570.619ACHN-975
CAS:ACHN-975: potent LpxC inhibitor with subnanomolar activity; targets many gram-negative bacteria; MIC ≤1 μg/mL.Fórmula:C20H23N3O4Pureza:98%Cor e Forma:SolidPeso molecular:369.41HBV-IN-12
CAS:HBV-IN-12: strong HBsAg & HBV DNA inhibitor; EC50 0.001-0.05 μM & 0.001-0.02 μM respectively. (WO2021204252A1)Fórmula:C23H27NO8Cor e Forma:SolidPeso molecular:445.46Glutamate-5-kinase-IN-1
Glutamate-5-kinase-IN-1 is a potent G5K inhibitor with a 4.1 μM MIC, showing promise in anti-TB research.Fórmula:C20H18N2OCor e Forma:SolidPeso molecular:302.37(Z)-Lanoconazole
<p>(Z)-Lanoconazole, an imidazole antifungal for dermatophytosis and onychomycosis, inhibits fungal ergosterol production.</p>Fórmula:C14H10ClN3S2Cor e Forma:SolidPeso molecular:319.83Benzohydroxamic acid
CAS:<p>Benzohydroxamic acid (BHA) is a chitin deacetylase (CDA) inhibitor with notable antifungal properties. It displays Ki values of 8.31 μM against Verticillium dahliae CDA and 9.83 μM against Puccinia striiformis f. sp. tritici CDA. BHA can restore the defense responses in infected host plants by upregulating the expression of defense-related genes, thereby reducing fungal growth and proliferation within the plants. It is applicable in the research of agricultural fungal diseases, such as cotton wilt and wheat stripe rust, caused by pathogens like Verticillium dahliae and Puccinia striiformis.</p>Fórmula:C7H7NO2Cor e Forma:SolidPeso molecular:137.136RAD51-IN-7
CAS:RAD51-IN-7 inhibits RAD51 gene, with potential for mitochondrial disorders. (From WO2021164746A1, cmpd 71)Fórmula:C25H31N5O4S2Cor e Forma:SolidPeso molecular:529.67MED6-189
CAS:MED6-189, an analog of kalihinol, disrupts the apicoplast functions and vesicular transport in the malignant malaria parasite (P. falciparum, IC50 < 50 nM). The compound specifically targets the apicoplast, which is a non-photosynthetic plastid essential for isoprenoid synthesis, found in most apicomplexan parasites.Fórmula:C17H26N2OCor e Forma:SolidPeso molecular:274.40LeuRS-IN-1 hydrochloride
CAS:<p>LeuRS-IN-1 hydrochloride is a Mycobacterium tuberculosis leucyl-tRNA synthetase inhibitor with antileukemic activity and antimalarial activity.</p>Fórmula:C10H14BCl2NO3Pureza:97.34% - 99.61%Cor e Forma:SolidPeso molecular:277.94JTK-109
CAS:JTK-109 is an inhibitor of hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitor and inhibits G1b and G3a subgenomic replicons and recombinant enzymes.Fórmula:C37H33ClFN3O4Pureza:98.48% - 99.68%Cor e Forma:SolidPeso molecular:638.13HRO761
CAS:HRO761 is a potent Werne r syndrome RecQ DNA deconjugase (WRN) inhibitor that can be used to study cancers such as colon and stomach cancer.Fórmula:C31H31ClF3N9O5Pureza:98.74% - 99.62%Cor e Forma:SolidPeso molecular:702.08Vaniprevir
CAS:Vaniprevir is a competitive HCV NS3/4A protease inhibitor, an antiviral(hepatitis C virus) drug that acts directly and blocks the viral replication process.Fórmula:C38H55N5O9SPureza:97.41%Cor e Forma:SolidPeso molecular:757.94Rupintrivir
CAS:Rupintrivirvr (AG7088) is a mimetic peptide inhibitor of rhinovirus (HRV) 3C cysteine protease with antiviral activity for the study of viral infections.Fórmula:C31H39FN4O7Pureza:97.72% - 99.35%Cor e Forma:SolidPeso molecular:598.66Tigemonam
CAS:<p>Tigemonam is a monobactam, a novel orally administered monobactam that protects against gram-negative aerobic bacterial pathogens. Cost-effective and quality-assured.</p>Fórmula:C12H15N5O9S2Pureza:99.03% - >99.99%Cor e Forma:SolidPeso molecular:437.41CCF0058981
CAS:<p>CCF0058981: noncovalent inhibitor for SARS-CoV-2 & -1 proteases; IC50s: 68 nM (SC2) & 19 nM (SC1). Potential COVID-19 research use.</p>Fórmula:C24H19ClN6OPureza:98.94%Cor e Forma:SoildPeso molecular:442.9D75-4590
CAS:<p>D75-4590, a β-1,6-Glucan synthetase inhibitor, combats fungal infections by targeting cell walls.</p>Fórmula:C21H27N5Pureza:98.56% - 98.85%Cor e Forma:SolidPeso molecular:349.47IDX184
CAS:IDX184 is a potent, orally active, targeted HCV polymerase inhibitor and nucleoside polymerase.IDX184 effectively inhibits HCV polymerase (IC50=0.31 μM, Ki=52.3Fórmula:C25H35N6O9PSPureza:97.15%Cor e Forma:SolidPeso molecular:626.62Cap-dependent endonuclease-IN-1
CAS:Cap-dependent endonuclease-IN-1: potent, oral inhibitor with antiviral properties against influenza.Fórmula:C27H22F2N2O6SPureza:99.53% - 99.61%Cor e Forma:SolidPeso molecular:540.54CTPS1-IN-1
CAS:CTPS1-IN-1 is a cytidine-5′ triphosphate synthase 1 (CTPS1) inhibitor with potential antitumor activity and can be used to study autoimmune diseases.Fórmula:C21H22N6O4S2Pureza:99.46%Cor e Forma:SolidPeso molecular:486.57Eravacycline dihydrochloride
CAS:<p>Eravacycline dihydrochloride (TP-434-046) is a potent and broad-spectrum antibacterial agent against six E. coli (MICs: 0.125-0.25 mg/L).</p>Fórmula:C27H33Cl2FN4O8Pureza:94.59% - 95%Cor e Forma:SolidPeso molecular:631.48SR 11302
CAS:SR 11302 is an inhibitor of activator protein-1 (AP-1).Fórmula:C26H32O2Pureza:98.65%Cor e Forma:SolidPeso molecular:376.53Durlobactam sodium salt
CAS:Durlobactam sodium salt (ETX2514) have an IC50 values of 4, 14 and 190 nM against class A KPC-2, class C AmpC and class D OXA-24.Cost-effective and quality-assured.Fórmula:C8H10N3NaO6SPureza:97.01% - 99.03%Cor e Forma:SolidPeso molecular:299.23FGI-106 tetrahydrochloride
CAS:FGI-106 tetrahydrochloride demonstrates potent inhibitory activity across a broad spectrum of viruses, including those causing hemorrhagic fevers such as EbolaFórmula:C28H42Cl4N6Pureza:99.68%Cor e Forma:SolidPeso molecular:604.48L-Eflornithine monohydrochloride
CAS:L-Eflornithine is an irreversible ornithine decarboxylase (ODC) inhibitor with a KD of 1.3±0.3 µM, and a Kinact of 0.15±0.03 min-1. L-Eflornithine monohydrochloride (L-DFMO monohydrochloride) is an enantiomer of Eflornithine.Fórmula:C6H13ClF2N2O2Cor e Forma:SolidPeso molecular:218.63Reutericyclin
CAS:Reutericyclin is a unique tetramic acid, is an antibiotic produced by some strains of Lactobacillus reuteri.Fórmula:C20H31NO4Pureza:98%Cor e Forma:SolidPeso molecular:349.46Haloxon
CAS:Haloxon is an organophosphorus anthelmintic. Haloxon is used against nematodes of the abomasum and small intestine in ruminants.Fórmula:C14H14Cl3O6PCor e Forma:SolidPeso molecular:415.59α-Terpineol
CAS:<p>Terpineol possesses antifungal activity against Trichophyton mentagrophytes, it also exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria. α-Terpineol (Terpineol) shows anticonvulsant, and anti-inflammatory activities, it inhibits the gene expression of the IL-6 receptor.</p>Fórmula:C10H18OPureza:97.55%Cor e Forma:Colorless LiquidPeso molecular:154.252'-Hydroxy-4'-methylacetophenone
CAS:<p>2'-Hydroxy-4'-methylacetophenone, a phenolic compound isolated from Angelicae koreana roots possesses acaricidal property. 2'-Hydroxy-4'-methylacetophenone has acaricidal activity, it could be used in the preparation of 4'-methyl-2'-[(p-tolylsulfonyl) oxy] acetophenone.</p>Fórmula:C9H10O2Pureza:99.88%Cor e Forma:Black LiquidPeso molecular:150.17Ethynylcytidine
CAS:<p>Ethynylcytidine is a nucleoside antimetabolite.</p>Fórmula:C11H13N3O5Pureza:98%Cor e Forma:SolidPeso molecular:267.24A 53868A
CAS:<p>A 53868A is an antibiotic, it is isolated from Streptomyces luridus.</p>Fórmula:C11H22N3O5PPureza:98%Cor e Forma:SolidPeso molecular:307.287Sulfamonomethoxine sodium
CAS:<p>Sulfamonomethoxine sodium is a long-acting sulfonamide antibacterial agent utilized in blood kinetic studies; it inhibits dihydropteroate synthetase, thereby blocking folic acid synthesis [1].</p>Fórmula:C11H11N4NaO3SPureza:98%Cor e Forma:SolidPeso molecular:302.29Tetraconazole
CAS:Tetraconazole is an agent of pesticides.Fórmula:C13H11Cl2F4N3OCor e Forma:Liquid ViscousPeso molecular:372.14Lenampicillin hydrochloride
CAS:<p>Lenampicillin hydrochloride is an orally active prodrug of Ampicillin. Lenampicillin hydrochloride is an effective beta-lactam antibacterial agent that inhibits bacterial penicillin-binding proteins. It is applied in the investigation of suppurative skin </p>Fórmula:C21H24ClN3O7SPureza:98%Cor e Forma:SolidPeso molecular:497.95BMS-378806
<p>BMS-378806 is an HIV inhibitor with EC50: 0.85-26.5nM for various strains.</p>Fórmula:C22H22N4O4Pureza:98%Cor e Forma:SolidPeso molecular:406.43Phosalacine
CAS:<p>Phosalacine, isolated from Kitasatosporia phosalacinea, is a new herbicidal antibiotic that contains phosphinothricin.</p>Fórmula:C14H28N3O6PPureza:98%Cor e Forma:SolidPeso molecular:365.367Policresulen
CAS:<p>Policresulen is a useful organic compound for research related to life sciences. The catalog number is T66902 and the CAS number is 101418-00-2.</p>Fórmula:C8H10O5SCor e Forma:SolidPeso molecular:218.22N-Butylthiophosphoric triamide
CAS:<p>N-Butylthiophosphoric triamide is a useful organic compound for research related to life sciences. The catalog number is T65336 and the CAS number is 94317-64-3.</p>Fórmula:C4H14N3PSCor e Forma:SolidPeso molecular:167.21Rhizocticin A
CAS:Rhizocticin A is a potential inhibitor of threonine synthase.Fórmula:C11H22N5O6PPureza:98%Cor e Forma:SolidPeso molecular:351.3Stearyl gallate
CAS:Stearyl gallate is a useful organic compound for research related to life sciences. The catalog number is T65655 and the CAS number is 10361-12-3.Fórmula:C25H42O5Cor e Forma:SolidPeso molecular:422.606PqsR/LasR-IN-1
CAS:PqsR/LasR-IN-1 (Compound 2a) is a potent inhibitor of LasR and PqsR systems in P. aeruginosa. PqsR/LasR-IN-1 is also a inhibitor of hERG (IC50= 6.77 μM).Fórmula:C24H20ClNO3Cor e Forma:SolidPeso molecular:405.87MuRF1-IN-2
CAS:MuRF1-IN-2 (Example 3) is a MuRF1 inhibitor used to study conditions linked to muscle wasting, encompassing both skeletal and cardiac muscle atrophy [1].Fórmula:C23H22N2O7Pureza:98%Cor e Forma:SolidPeso molecular:438.435'-O-DMT-N6-ibu-dA
CAS:5'-O-DMT-N6-ibu-dA can be utilized in the synthesis of oligodeoxyribonucleotides.Fórmula:C35H37N5O6Cor e Forma:SolidPeso molecular:623.71ABT-072 potassium trihydrate
CAS:ABT-072, also known as potassium trihydrate, is a highly effective non-nucleoside inhibitor of the HCV NS5B polymerase, administered orally. This compound exhibits potent activity against HCV GT1a (with an EC50 of 1 nM) and HCV GT1b (with an EC50 of 0.3 nM).Fórmula:C24H32KN3O8SCor e Forma:SolidPeso molecular:561.69Oleandomycin
CAS:Oleandomycin, a macrolide antibiotic structurally similar to Erythromycin, exhibits antimicrobial activity.Fórmula:C35H61NO12Pureza:98%Cor e Forma:White Amorphous Powder SolidPeso molecular:687.86trans-Clopenthixol dihydrochloride
CAS:<p>Trans-Clopenthixol dihydrochloride ((E)-Clopenthixol dihydrochloride), an antibiotic without neuroleptic effects, has demonstrated in vitro efficacy against Pseudomonas aeruginosa and Plasmodium falciparum, as referenced in [1] [2].</p>Fórmula:C22H27Cl3N2OSPureza:98%Cor e Forma:SolidPeso molecular:473.89Pulcherriminic acid
CAS:<p>Pulcherriminic acid, a cyclic dipeptide, chelates Fe3+, forms pulcherrimin, and has antimicrobial properties used in food, agriculture, and medicine.</p>Fórmula:C12H20N2O4Cor e Forma:SolidPeso molecular:256.30l-Atabrine dihydrochloride
CAS:l-Atabrine dihydrochloride displays antiprion activity. l-Atabrine dihydrochloride is a less active enantiomer of quinacrine.Fórmula:C23H31Cl2N3OPureza:98%Cor e Forma:SolidPeso molecular:436.42Erythromycylamine
CAS:Erythromycylamine is a useful organic compound for research related to life sciences. The catalog number is T64443 and the CAS number is 26116-56-3.Fórmula:C37H70N2O12Cor e Forma:SolidPeso molecular:734.969Darobactin
CAS:<p>Darobactin is an antibiotic effective against critical Gram-negative pathogens, demonstrating activity both in vitro and in animal infection models [1].</p>Fórmula:C47H55N11O12Pureza:98%Cor e Forma:SolidPeso molecular:966.01Ramifenazone
CAS:Ramifenazone is a drug of nonsteroidal anti-inflammatory.Fórmula:C14H19N3OPureza:98%Cor e Forma:SolidPeso molecular:245.322-Mercaptopyridine N-oxide sodium
CAS:<p>2-Mercaptopyridine N-oxide sodium is a useful organic compound for research related to life sciences. The catalog number is T66776 and the CAS number is 3811-73-2.</p>Fórmula:C5H4NNaOSCor e Forma:SolidPeso molecular:149.14(S)-2-Ethylbutyl 2-(((S)-(4-nitrophenoxy)(phenoxy)phosphoryl)amino)propanoate
CAS:(S)-2-Ethylbutyl 2-(((S)-(4-nitrophenoxy)(phenoxy)phosphoryl)amino)propanoate is a useful organic compound for research related to life sciences. The catalog number is T64602 and the CAS number is 1354823-36-1.Fórmula:C21H27N2O7PCor e Forma:SolidPeso molecular:450.428Ulifloxacin
CAS:Ulifloxacin is a useful organic compound for research related to life sciences. The catalog number is T65577 and the CAS number is 112984-60-8.Fórmula:C16H16FN3O3SCor e Forma:SolidPeso molecular:349.38CRS3123 dihydrochloride
CAS:CRS3123 (REP-3123) dihydrochloride is an orally active, fully synthetic antimicrobial agent that effectively inhibits Clostridioides difficile methionyl-tRNA synthetase (MetRS). CRS3123 dihydrochloride can be used in the study of Clostridioides difficile infection (CDI).Fórmula:C19H21Br2Cl2N3O2SCor e Forma:SolidPeso molecular:586.16Cefetamet pivoxyl
CAS:<p>Cefetamet pivoxyl, a cephalosporin antibiotic, effectively inhibits 355 enteropathogens, including Gram-negative bacteria (ausgenommen Pseudomonas aeruginosa) and Legionella pneumophila [1].</p>Fórmula:C20H25N5O7S2Pureza:98%Cor e Forma:SolidPeso molecular:511.57Antiviral agent 5
CAS:Antiviral agent 5 is a crucial intermediate utilized in the development of antiviral agents that specifically target 3C and 3CL proteases, which includes the SARS-CoV-2 M pro enzyme.Fórmula:C18H30N2O7Cor e Forma:SolidPeso molecular:386.445Bacampicillin hydrochloride
CAS:Bacampicillin hydrochloride is an improved oral bioavailability penicillin antibiotic which is a prodrug of ampicillin.Fórmula:C21H28ClN3O7SPureza:98%Cor e Forma:SolidPeso molecular:501.985'-DMT-3'-TBDMS-ibu-rG
CAS:<p>5'-DMT-3'-TBDMS-ibu-rG is a modified nucleoside employed in deoxyribonucleic acid (DNA) synthesis.</p>Fórmula:C41H51N5O8SiCor e Forma:SolidPeso molecular:769.96Pseudomonic acid C
CAS:Pseudomonic acid C is the analogue of Pseudomonic Acid D which is an antibiotic agent from Pseudomonas fluorescens.Fórmula:C26H44O8Pureza:98%Cor e Forma:SolidPeso molecular:484.621-Naphthalenemethanol
CAS:1-Naphthalenemethanol is a natural product for research related to life sciences. The catalog number is T67143 and the CAS number is 4780-79-4.Fórmula:C11H10OCor e Forma:SolidPeso molecular:158.2Ethyl 4-hydroxy-2-methyl-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxide
CAS:Ethyl 4-hydroxy-2-methyl-2H-benzo[e][1,2]thiazine-3-carboxylate 1,1-dioxide is a useful organic compound for research related to life sciences. The catalog number is T65688 and the CAS number is 24683-26-9.Fórmula:C12H13NO5SCor e Forma:SolidPeso molecular:283.3FtsZ-IN-10
CAS:<p>Compound GK02084(SC) may have activity against the GTP site of Bs‐FtsZ.</p>Fórmula:C15H13ClN2O4SPureza:98%Cor e Forma:SolidPeso molecular:352.79Nortopixantrone
CAS:<p>Nortopixantrone(BBR 3438) is a novel 9-azacyclophenanthracene pyrazole that shows antitumor activity in a human prostate cancer model.</p>Fórmula:C20H24N6O2Pureza:>99.99%Cor e Forma:SolidPeso molecular:380.44NSC639828
CAS:NSC639828 is an efficient inhibitor of DNA polymerase α, exhibiting a remarkable IC50 value of 70 μM. Additionally, NSC639828 demonstrates substantial antitumor activity, making it a promising candidate for cancer research.Fórmula:C18H13BrClN5O3Cor e Forma:SolidPeso molecular:462.69Hexahydrohippuric acid
CAS:Hexahydrohippuric acid is a useful organic compound for research related to life sciences. The catalog number is T65235 and the CAS number is 32377-88-1.Fórmula:C9H15NO3Cor e Forma:SolidPeso molecular:185.223Oxindole
CAS:<p>Oxindole (Indolin-2-one) is an aromatic heterocyclic building block. 2-indolinone derivatives have become lead compounds in the research of kinase inhibitors.Oxindole structure has been used in receptor tyrosine kinases (RTKs) inhibitors such as SU4984 and intedanib, the RTK family represents an important therapeutic target for anti-cancer drug development.</p>Fórmula:C8H7NOPureza:99.34%Cor e Forma:Off-White Crystalline PowderPeso molecular:133.15TP0586532
CAS:<p>TP0586532 is effective against carbapenem-resistant Klebsiella pneumoniae and does not pose a cardiovascular risk.</p>Fórmula:C26H28N4O4Pureza:98%Cor e Forma:SolidPeso molecular:460.52Pritelivir mesylate
CAS:Pritelivir mesylate is active against herpes simplex virus types 1 and 2 (IC50: 0.02 μM against HSV1-2). Pritelivir mesylate is an inhibitor of the viral helicase-primase complex. Pritelivir mesylate shows antiviral activity in vitro and in animal modelsFórmula:C19H22N4O6S3Pureza:98%Cor e Forma:SolidPeso molecular:498.6PKUMDL-LTQ-301
CAS:PKUMDL-LTQ-301 is a potent inhibitor of HipA toxin. PKUMDL-LTQ-301 also inhibits E. coli persistence.Fórmula:C30H28N2O4Pureza:98%Cor e Forma:SolidPeso molecular:480.55MitoE10
CAS:MitoE10 is an effective mitochondrial targeting antioxidant.Fórmula:C42H55O5PSCor e Forma:SolidPeso molecular:702.92HIV-1 integrase inhibitor
CAS:Hiv-1 integrase inhibitor is an effective anti-HIV drug.Fórmula:C11H9N3O4Pureza:98%Cor e Forma:SolidPeso molecular:247.21d-Atabrine dihydrochloride
CAS:d-Atabrine hydrochloride is the active enantiomer of quinacrine and has anti-pr virus activity.Fórmula:C23H31Cl2N3OPureza:98%Cor e Forma:SolidPeso molecular:436.42DprE1-IN-8
CAS:<p>DprE1-IN-8 is a potent inhibitor of DprE1, exhibiting an IC50 of less than 0.75 μM.</p>Fórmula:C19H12F3N5O4SPureza:98%Cor e Forma:SolidPeso molecular:463.39Ref: TM-T79628
Produto descontinuadoHBV-IN-34
CAS:<p>HBV-IN-34 (compound 17i) is a potent inhibitor of HBsAg production, demonstrating remarkable in vitro anti-HBV efficacy with EC50 values of 0.018 μM for HBV DNA</p>Fórmula:C21H19F2N7Pureza:98%Cor e Forma:SolidPeso molecular:407.42Ref: TM-T79469
Produto descontinuadoSARS-CoV-2-IN-68
CAS:<p>SARS-CoV-2-IN-68 (compound 6C) is a covalent inhibitor of both SARS-CoV-2 PLpro and Mpro, exhibiting potent antiviral properties by targeting the Zn-finger</p>Fórmula:C14H12N2OSePureza:98%Cor e Forma:SolidPeso molecular:303.22HBV-IN-38
CAS:<p>HBV-IN-38 (Example 193), an HBV DNA inhibitor with an EC50 value of ≤100 nM, serves as a research tool for investigating viral infections [1].</p>Fórmula:C18H16F3N5O4S2Pureza:98%Cor e Forma:SolidPeso molecular:487.48Yhhu6669
CAS:<p>Yhhu6669 is an anti-HBV agent that suppresses viral DNA and replication by promoting DNA-free capsid assembly, effectively reducing HBV DNA and HBcAg levels in</p>Fórmula:C29H28ClFN6O3Pureza:98%Cor e Forma:SolidPeso molecular:563.02Ref: TM-T78756
Produto descontinuadoInsecticidal agent 6
CAS:<p>Compound Im (Insecticidal agent 6) is a potent inhibitor of insect ryanodine receptors (RyRs), exhibiting an EC50 of 0.6308 µM against S.</p>Fórmula:C19H14BrCl2N5O4Pureza:98%Cor e Forma:SolidPeso molecular:527.16Cap-dependent endonuclease-IN-9
CAS:<p>Cap-dependent endonuclease-IN-9, a strong influenza inhibitor, shows low toxicity, good pharmacokinetics, and dynamic action.</p>Fórmula:C29H22F2N4O7SPureza:98%Cor e Forma:SolidPeso molecular:608.57Ref: TM-T72125
Produto descontinuado
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