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Microbiologia/Virologia

Microbiologia/Virologia

Os inibidores de microbiologia e virologia são compostos que têm como alvo microrganismos, incluindo bactérias, vírus e fungos, interrompendo seu crescimento, replicação ou sobrevivência. Esses inibidores são essenciais para estudar a patogênese microbiana, entender os mecanismos de resistência e desenvolver novas terapias antimicrobianas e antivirais. Os inibidores nessa categoria são usados para combater doenças infecciosas, explorar a ecologia microbiana e investigar as interações hospedeiro-patógeno. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para microbiologia e virologia para apoiar sua pesquisa em doenças infecciosas, microbiologia e virologia.

Subcategorias de "Microbiologia/Virologia"

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Foram encontrados 5832 produtos de "Microbiologia/Virologia"

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  • A7132

    CAS:
    <p>A7132 is an antibacterial agent and possesses broad and potent antibacterial activity.</p>
    Fórmula:C19H16F2N4O3
    Pureza:95.49%
    Cor e Forma:Solid
    Peso molecular:386.35
  • MMV688533

    CAS:
    <p>MMV688533 has antimalarial activity.</p>
    Fórmula:C24H15F6N5O2
    Pureza:99.12%
    Cor e Forma:Soild
    Peso molecular:519.4
  • Ziresovir

    CAS:
    <p>Ziresovir (RO-0529) is a respiratory syncytial virus fusion protein (RSV F) inhibitor that inhibits RSV and can be used to study syncytial virus sense.</p>
    Fórmula:C22H25N5O3S
    Pureza:95.51% - >99.99%
    Cor e Forma:Solid
    Peso molecular:439.53
  • Thymectacin

    CAS:
    <p>Thymectacin (NB 1011) is a selective thymidine synthase (TS) inhibitor with anticancer activity for the study of colon cancer and solid tumors.</p>
    Fórmula:C21H25BrN3O9P
    Pureza:97.05% - 99.49%
    Cor e Forma:Solid
    Peso molecular:574.32
  • LNA-Adenosine

    CAS:
    <p>LNA-Adenosine (LNA-A) is a nucleoside analogue that acts as a ligand for adenosine A3 receptors.</p>
    Fórmula:C11H13N5O4
    Pureza:99.15%
    Cor e Forma:Solid
    Peso molecular:279.25
  • Dehydroemetine

    CAS:
    <p>Dehydroemetine, a synthetic emetine, treats amoebic infections and leishmaniasis, and resists metronidazole amoebiosis.</p>
    Fórmula:C29H38N2O4
    Pureza:98.68% - 99.68%
    Cor e Forma:Solid
    Peso molecular:478.62
  • 2,4′-Dichloroacetanilide

    CAS:
    <p>2,4′-Dichloroacetanilide (2-chloro-N-(4-chlorophenyl)acetamide) has antifungal activity and inhibits T. asteroides with a MIC value of 6.25 μg/mL.</p>
    Fórmula:C8H7Cl2NO
    Pureza:99.36%
    Cor e Forma:Solid
    Peso molecular:204.05
  • Valomaciclovir stearate

    CAS:
    <p>S-Allylmercapturic Acid (N-Acetyl-S-allyl-L-cysteine) is a metabolite of S-allyl-L-cysteine present in black garlic, with potential anti-gout effects.</p>
    Fórmula:C33H58N6O5
    Pureza:99.18% - >99.99%
    Cor e Forma:Solid
    Peso molecular:618.85
  • CWHM-1552

    CAS:
    <p>CWHM-1552 is an effective Plasmodium falciparum inhibitor. For the 3D7 and Dd2 strains, the IC50s are 51 nM and 53 nM.</p>
    Fórmula:C22H27F2N3O
    Pureza:99.56%
    Cor e Forma:Solid
    Peso molecular:387.47
  • TCMDC-135051

    CAS:
    <p>TCMDC-135051: Selective PfCLK3 inhibitor, low toxicity, halts parasite growth &amp; transmission; EC50=320 nM.</p>
    Fórmula:C29H33N3O3
    Pureza:99.05%
    Cor e Forma:Solid
    Peso molecular:471.59
  • Tenofovir amibufenamide

    CAS:
    <p>Tenofovir amibufenamide (HS-10234) 是一种 Tenofovir 前药,是一种具有口服活性的抗病毒化合物。Tenofovir amibufenamide 对乙型肝炎病毒 (HBV)具有抑制作用,可用于慢性乙型肝炎 (CHB) 研究。</p>
    Fórmula:C22H31N6O5P
    Pureza:99.19% - 99.87%
    Cor e Forma:Solid
    Peso molecular:490.49
  • Filibuvir

    CAS:
    <p>Filibuvir (PF-00868554) inhibits HCV polymerase genotypes 1a/1b, EC50s 59 nM.</p>
    Fórmula:C29H37N5O3
    Pureza:99.28% - >99.99%
    Cor e Forma:Solid
    Peso molecular:503.64
  • DHX9-IN-2

    CAS:
    <p>DHX9-IN-2 is an inhibitor targeting ATP-dependent RNA de-helicase A (DHX9) with anticancer and antitumor activity for cancer research.</p>
    Fórmula:C18H16ClN3O3S2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:421.92
  • SMN-C3

    CAS:
    <p>SMN-C3 (MV8T2MCK57) is an orally active modulator of SMN2 splicing, and has the potential to treat spinal muscular atrophy (SMA).</p>
    Fórmula:C24H28N6O
    Pureza:99.01% - 99.05%
    Cor e Forma:Solid
    Peso molecular:416.52
  • Leritrelvir

    CAS:
    <p>Dermatan sulphate sodium (Chondroitin sulfate B sodium salt) is a linear sulfated polysaccharide, a glycosaminoglycan component of important proteoglycans.</p>
    Fórmula:C31H44F3N5O6
    Pureza:97.42%
    Cor e Forma:Solid
    Peso molecular:639.71
  • GSK3186899

    CAS:
    <p>GSK3186899 is an inhibitor of Cdc2-related kinase 12 with an EC50 of 1.4 μM for L. donovani.</p>
    Fórmula:C19H28F3N7O3S
    Pureza:98.35% - 99.61%
    Cor e Forma:Solid
    Peso molecular:491.53
  • Contezolid

    CAS:
    <p>Contezolid (MRX-I) is an antibiotic with bactericidal activity and can be used to study tuberculosis.</p>
    Fórmula:C18H15F3N4O4
    Pureza:99.41%
    Cor e Forma:Solid
    Peso molecular:408.33
  • Lomibuvir

    CAS:
    <p>Lomibuvir (VCH-222, VX-222) is an allosteric inhibitor of HCV NS5B with Kd 17 nM, blocks RNA elongation, EC50 5.2 nM for 1b/Con1.</p>
    Fórmula:C25H35NO4S
    Pureza:99.83%
    Cor e Forma:Solid
    Peso molecular:445.61
  • Sorivudine

    CAS:
    <p>Sorivudine (BV-araU) is an antiviral blocking DNA synthesis in viruses like varicella, HSV-1, and Epstein-Barr.</p>
    Fórmula:C11H13BrN2O6
    Pureza:99.74%
    Cor e Forma:Solid
    Peso molecular:349.13
  • CeMMEC1

    CAS:
    <p>CeMMEC1 is an inhibitor of BRD4, and also has a great affinity for TAF1(IC50=0.9 μM).</p>
    Fórmula:C19H16N2O4
    Pureza:98.9% - 99.92%
    Cor e Forma:Solid
    Peso molecular:336.34
  • Neocryptolepine-Cl

    CAS:
    <p>Neocryptolepine-Cl (compound Z24) is an inhibitor of Bcthi4, demonstrating excellent antifungal activity against B. cinerea, with an EC50 value of 0.56 μg/mL.</p>
    Fórmula:C16H11ClN2
    Cor e Forma:Solid
    Peso molecular:266.725
  • Pks13-TE inhibitor 4

    CAS:
    <p>Pks13-TE inhibitor 4 (compound 44) is a potent inhibitor from the thiazole series that effectively targets Pks13 to combat tuberculosis (TB) and addresses drug resistance.</p>
    Fórmula:C26H25N5O6
    Peso molecular:503.51
  • Purine phosphoribosyltransferase-IN-1


    <p>Compound (S,R)-48 inhibits Pf, Pv, &amp; Tbr PRT with Ki of 50, 20, 2 nM.</p>
    Fórmula:C11H15N5Na4O10P2
    Cor e Forma:Solid
    Peso molecular:531.17
  • Elongation factor P-IN-1


    <p>EFP-IN-1: potent β-lysine derivative, inhibits EFP, slows E. coli growth.</p>
    Fórmula:C14H31N3O2
    Cor e Forma:Solid
    Peso molecular:273.41
  • GC-78-HCl

    CAS:
    <p>GC-78-HCl is an orally active, non-peptidic SARS-CoV-2 Mpro inhibitor with an enzyme IC50 of 0.19 μM. It exhibits strong anti-coronavirus activity and favorable pharmacokinetic properties.</p>
    Fórmula:C25H25Cl3N4O4
    Peso molecular:551.85
  • FtsZ-IN-4


    <p>FtsZ-IN-4 is an oral FtsZ inhibitor with strong antibacterial effects and good drug traits, low toxicity (CC50 &gt;20μg/mL).</p>
    Fórmula:C21H16ClF2NO2
    Cor e Forma:Solid
    Peso molecular:387.81
  • HIV-1 protease-IN-6


    <p>HIV-1 protease-IN-6 (17d) strongly inhibits HIV-1 protease (IC50: 21 pM, Ki: 4.7 pM) and effectively targets DRV-resistant mutants.</p>
    Fórmula:C27H31FN2O6S
    Cor e Forma:Solid
    Peso molecular:530.61
  • SID 26681509 quarterhydrate


    <p>SID 26681509 is a selective inhibitor of cathepsin L (IC50: 56 nM) and blocks Plasmodium falciparum (IC50: 15.4 μM) and Leishmania major (IC50: 12.5 μM).</p>
    Fórmula:C27H35N5O6S
    Cor e Forma:Solid
    Peso molecular:544.16
  • HCV NS5B polymerase-IN-2

    CAS:
    <p>HCVNS5B polymerase-IN-2 (Compound 298) is an inhibitor of the Ns5b polymerase. It holds potential for research into the treatment of hepatitis C virus (HCV) infections.</p>
    Fórmula:C26H24N2O4
    Cor e Forma:Solid
    Peso molecular:428.48
  • Anti-infective agent 10

    CAS:
    <p>Anti-infective agent 10 (Compound Example 30) is an ns5b polymerase inhibitor that functions as an anti-HCV agent.</p>
    Fórmula:C26H25N3O7S
    Cor e Forma:Solid
    Peso molecular:523.56
  • Nikkomycin Z

    CAS:
    <p>Nikkomycin Z (Nikkomycin Z from Streptomyces tendae) is a competitive chitin synthase inhibitor.It inhibitor of the growth of filamentous fungi, insects,</p>
    Fórmula:C20H25N5O10
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:495.44
  • LY 215890

    CAS:
    <p>LY 215890 is a compound that exhibits potent Gram-negative and Gram-positive antibacterial activity.</p>
    Fórmula:C13H12ClN5O5S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:385.78
  • 2'-Amino-2'-deoxyadenosine

    CAS:
    <p>2'-Amino-2'-deoxyadenosine (9-(2-Amino-2-deoxypentofuranosyl)-9H-purin-6-amine) is a nucleoside antibiotic that effectively inhibits various Mycoplasma strains.</p>
    Fórmula:C10H14N6O3
    Peso molecular:266.26
  • Antifungal agent 25


    <p>Antifungal agent 25: broad-spectrum, stable in vivo, effective against Candida albicans, including fluconazole-resistant strains.</p>
    Cor e Forma:Solid
  • WRN inhibitor 7

    CAS:
    <p>WRN inhibitor 7 (Compound h6), a potent inhibitor of Werner syndrome helicase, demonstrates effective suppression of WRN's helicase and ATPase activities with IC50 values of 9.8 μM and 15.8 μM, respectively. This compound is utilized in the study of microsatellite instable (MSI) cancers [1].</p>
    Fórmula:C27H23N3O6
    Cor e Forma:Solid
    Peso molecular:485.49
  • GRL-190-21

    CAS:
    <p>GRL-190-21 (compound 5e), an inhibitor of SARS-Cov-2-Mpro, shows potent antiviral activity, with a K_i of 0.04 nM and an EC_50 of 0.26 μM in VeroE6 cells. It significantly reduces the infectivity, replication, and cytopathic effect of SARS-CoV-2 without notable toxicity [1].</p>
    Fórmula:C24H34F3N5O4
    Cor e Forma:Solid
    Peso molecular:513.55
  • MMV03

    CAS:
    <p>MMV03 is an antimalarial compound effective against Plasmodium falciparum, with an EC50 of 0.6 μM.</p>
    Fórmula:C19H14N4OS
    Cor e Forma:Solid
    Peso molecular:346.406
  • SARS-CoV-2-IN-80

    CAS:
    <p>SARS-CoV-2-IN-80 (compound 13), identified as a potent inhibitor of SARS-CoV-2 3CLpro, exhibits an IC50 value of 0.964 µM [1].</p>
    Fórmula:C16H10O2S
    Cor e Forma:Solid
    Peso molecular:266.31
  • CTSL/CAPN1-IN-2

    CAS:
    <p>CTSL/CAPN1-IN-2 (Compound 14b) serves as an orally active inhibitor targeting both CTSL and CAPN1, manifesting IC50 values of 6.88 nM for CTSL and 347.6 nM for CAPN1 respectively. This compound not only displays anti-inflammatory attributes but also features favorable pharmacokinetic properties. Moreover, CTSL/CAPN1-IN-2 shows extensive antiviral effects against coronaviruses by inhibiting viral entry [1].</p>
    Fórmula:C34H40N4O6
    Cor e Forma:Solid
    Peso molecular:600.7
  • RECTAS-2.0

    CAS:
    <p>RECTAS-2.0 is a small molecule designed to correct RNA mis-splicing caused by the GLA c.639+919G&gt;A mutation, intended for research in Fabry disease.</p>
    Fórmula:C18H17ClN4O4
    Cor e Forma:Solid
    Peso molecular:388.805
  • Antibacterial agent 204

    CAS:
    <p>Antibacterial agent 204 (Compd P2-56-3) enhances the activity of Rifampin (RIF) against Acinetobacter baumannii and Klebsiella pneumoniae by disrupting the outer membrane of A. baumannii. T [1].</p>
    Fórmula:C14H18N2
    Cor e Forma:Solid
    Peso molecular:214.31
  • HKI12134085

    CAS:
    <p>HKI12134085 (compound 3), an orally administered nitrobenzothiazinone (BTZ) derivative, demonstrates antibacterial efficacy against Mycobacterium tuberculosis. This compound exhibits significant in vivo inhibitory potency within a BALB/c mouse model of Mycobacterium tuberculosis infection [1].</p>
    Fórmula:C18H18F3N3O5S
    Cor e Forma:Solid
    Peso molecular:445.41
  • β-Glucuronidase-IN-3

    CAS:
    <p>β-Glucuronidase-IN-3 (Compound 49) is a covalent allosteric inhibitor targeting β-glucuronidase. It exhibits potent inhibitory activity against Escherichia coli β-glucuronidase (EcGUS) with an IC50 of 12.9 nM. The compound exerts its inhibitory effect through reversible covalent modification of cysteine residues (Cys28, Cys443, and Cys197) on EcGUS. It is applicable in research on gut microbiota-related diseases, particularly in reducing the toxic side effects of Irinotecan and non-steroidal anti-inflammatory drugs (NSAIDs).</p>
    Fórmula:C10H7N3OSe
    Cor e Forma:Solid
    Peso molecular:264.14
  • Pneumolysin-IN-1

    CAS:
    <p>Pneumolysin-IN-1 (compound PB-3), characterized as a targeted small molecule inhibitor of Pneumolysin (PLY) with an IC50 value of 3.1 µM, acts as a pore-blocking agent and an anti-virulence factor. This compound is useful for researching infections caused by Streptococcus pneumoniae [1].</p>
    Fórmula:C23H16Cl2N2O4
    Cor e Forma:Solid
    Peso molecular:455.29
  • Neuraminidase-IN-18

    CAS:
    <p>Neuraminidase-IN-18 (compound N5), a novel polyheterocyclic neuraminidase (NA) inhibitor, demonstrates significant inhibitory activity against H5N1 NA, with an IC 50 of 0.14 μM against the wild-type H5N1 NA and 0.27 μM against the H5N1-H274Y mutant NA. This compound effectively binds to NAs, inhibiting influenza virus replication at the cellular level [1].</p>
    Fórmula:C22H18FN3O3S
    Cor e Forma:Solid
    Peso molecular:423.46
  • N-Cbz-L-Cysteine

    CAS:
    <p>N-Cbz-L-Cysteine (Cbz-cysteine) (compound 5) functions as a potent inhibitor of β-lactamase II, exhibiting a K i value of 97 µM [1].</p>
    Fórmula:C11H13NO4S
    Cor e Forma:Solid
    Peso molecular:255.29
  • Antifungal agent 28


    <p>Antifungal 28 disrupts Candida, hits fluconazole-resistant strains, and inhibits biofilms.</p>
    Fórmula:C22H29N5OS
    Cor e Forma:Solid
    Peso molecular:411.56
  • Antimalarial agent 48

    CAS:
    <p>Antimalarial agent 48 (Compound 15a) is a triazine compound with antimalarial activity, showing effectiveness against Plasmodium falciparum K1 and Plasmodium falciparum FCR3 with IC50 values of 280 and 290 nM, respectively. It holds promise for research in the field of anti-infective treatments.</p>
    Fórmula:C19H14F3N11
    Cor e Forma:Solid
    Peso molecular:453.383
  • BDM91288

    CAS:
    <p>BDM91288, an orally active AcrB efflux pump inhibitor of pyridinium piperazine, enhances the in vivo efficacy of levofloxacin in treating Klebsiella pneumoniae pulmonary infection in mouse models [1].</p>
    Fórmula:C17H22ClN5
    Cor e Forma:Solid
    Peso molecular:331.84
  • VV261

    CAS:
    <p>VV261 is an orally active inhibitor of the Influenza Virus. It exhibits activity against the Severe Fever with Thrombocytopenia Syndrome Virus (SFTSV) and the Lymphocytic Choriomeningitis Virus (LCMV), with EC50 values of 0.89 and 0.15, respectively.</p>
    Fórmula:C28H34FN3O11
    Cor e Forma:Solid
    Peso molecular:607.58