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Microbiologia/Virologia

Microbiologia/Virologia

Os inibidores de microbiologia e virologia são compostos que têm como alvo microrganismos, incluindo bactérias, vírus e fungos, interrompendo seu crescimento, replicação ou sobrevivência. Esses inibidores são essenciais para estudar a patogênese microbiana, entender os mecanismos de resistência e desenvolver novas terapias antimicrobianas e antivirais. Os inibidores nessa categoria são usados para combater doenças infecciosas, explorar a ecologia microbiana e investigar as interações hospedeiro-patógeno. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para microbiologia e virologia para apoiar sua pesquisa em doenças infecciosas, microbiologia e virologia.

Subcategorias de "Microbiologia/Virologia"

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Foram encontrados 5842 produtos de "Microbiologia/Virologia"

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  • Carbodine

    CAS:
    <p>Carbodine is an antiviral targeting CTP synthetase, effective against influenza A0/PR-8/34 and A2/Aichi/2/68.</p>
    Fórmula:C10H15N3O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:241.24
  • (Z)-Lanoconazole


    <p>(Z)-Lanoconazole, an imidazole antifungal for dermatophytosis and onychomycosis, inhibits fungal ergosterol production.</p>
    Fórmula:C14H10ClN3S2
    Cor e Forma:Solid
    Peso molecular:319.83
  • D-G23

    CAS:
    <p>D-G23 is a selective RAD52 inhibitor. It disrupts RAD52-mediated DNA repair pathways and suppresses the growth of cancer cells deficient in BRCA1 and BRCA2. D-G23 shows promise for research into homologous recombination-related cancers caused by BRCA1/2 mutations, such as hereditary breast and ovarian cancers.</p>
    Fórmula:C19H22N4O3
    Cor e Forma:Solid
    Peso molecular:354.403
  • PptT-IN-1


    <p>PptT-IN-1, a potent PptT inhibitor (IC50: 2.8 μM), shows promise for tuberculosis research.</p>
    Fórmula:C18H29N5O2
    Cor e Forma:Solid
    Peso molecular:347.46
  • Dencatistat

    CAS:
    <p>Dencatistat is a highly selective and oral cytidine triphosphate synthase 1 CTPS1 inhibitor specific.CTPS1-IN-2 for B-cell, T-cell lymphomas and solid tumors.</p>
    Fórmula:C24H27N7O5S
    Pureza:98.85%
    Cor e Forma:Solid
    Peso molecular:525.58
  • PolQi1

    CAS:
    <p>PolQi1 is a highly efficient and selective Polϴ (DNA polymerase theta) inhibitor with an IC50 of 2 nM, showing potential for cancer therapy.</p>
    Fórmula:C18H14ClF5N4O2
    Pureza:98.97%
    Cor e Forma:Solid
    Peso molecular:448.77
  • Mycobacterium Tuberculosis-IN-6

    CAS:
    <p>Mycobacterium Tuberculosis-IN-6 (compound b1) is an inhibitor of the enoyl reductase InhA from Mycobacterium tuberculosis, with an IC50 value of 7.74 μM. It is useful in antibacterial research.</p>
    Fórmula:C19H20FNO
    Cor e Forma:Solid
    Peso molecular:297.367
  • Nikkomycin Z

    CAS:
    <p>Nikkomycin Z (Nikkomycin Z from Streptomyces tendae) is a competitive chitin synthase inhibitor.It inhibitor of the growth of filamentous fungi, insects,</p>
    Fórmula:C20H25N5O10
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:495.44
  • HBV-IN-31

    CAS:
    <p>HBV-IN-31: strong cccDNA inhibitor, anti-HBV, IC50=0.13 µM HBsAg, hampers cell growth.</p>
    Fórmula:C23H18ClNO6
    Cor e Forma:Solid
    Peso molecular:439.85
  • Antimalarial agent 9


    <p>Antimalarial 9, a quinoline-imidazole derivative, effectively targets CQ-susceptible (IC50-0.14 μM) and MDR strains (IC50-0.41 μM) with low toxicity.</p>
    Fórmula:C28H32BrN3O2
    Cor e Forma:Solid
    Peso molecular:522.48
  • SARS-CoV-2-IN-23


    <p>SARS-CoV-2-IN-23 (compound GRL-0617) is an inhibitor of SARS-COV-2 papain-like protease (PLpro) (IC 50 = 2.3 μM) [1].</p>
    Fórmula:C21H22N2O
    Cor e Forma:Solid
    Peso molecular:318.41
  • Benzohydroxamic acid

    CAS:
    <p>Benzohydroxamic acid (BHA) is a chitin deacetylase (CDA) inhibitor with notable antifungal properties. It displays Ki values of 8.31 μM against Verticillium dahliae CDA and 9.83 μM against Puccinia striiformis f. sp. tritici CDA. BHA can restore the defense responses in infected host plants by upregulating the expression of defense-related genes, thereby reducing fungal growth and proliferation within the plants. It is applicable in the research of agricultural fungal diseases, such as cotton wilt and wheat stripe rust, caused by pathogens like Verticillium dahliae and Puccinia striiformis.</p>
    Fórmula:C7H7NO2
    Cor e Forma:Solid
    Peso molecular:137.136
  • AN-12-H5

    CAS:
    <p>AN-12-H5 is an anti-enteroviral compound that targets the replication process of PV and EV71 viruses.</p>
    Fórmula:C24H23N3O4S3
    Cor e Forma:Solid
    Peso molecular:513.65
  • G092


    <p>G092 is a potent inhibitor of MsbA. MsbA is an ABC transporter protein. G092 has potential for antibacterial drug research.</p>
    Fórmula:C23H20Cl2N2O3
    Cor e Forma:Solid
    Peso molecular:443.32
  • MraY-IN-2


    <p>MraY-IN-2 (compound 6) is an effective inhibitor of bacterial transposase MraY (IC50=4.5 μ M), and can be used for antibacterial research.</p>
    Fórmula:C16H23N3O9
    Cor e Forma:Solid
    Peso molecular:401.37
  • GSK-2878175

    CAS:
    <p>GSK-2878175, a NS5B inhibitor, is used potentially for the treatment of HCV infection.</p>
    Fórmula:C27H23BClFN2O6S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:568.81
  • ZIKV-IN-5


    <p>ZIKV-IN-5 is an acid-stable, low cytotoxic anti-ZIKV agent with an EC50 value of 0.71 μM. ZIKV-IN-5 showed effective inhibition of ZIKV NS5 MTase activity.</p>
    Fórmula:C36H45NO4Si
    Cor e Forma:Solid
    Peso molecular:583.83
  • Adafosbuvir

    CAS:
    <p>Adafosbuvir has antiviral activity.</p>
    Fórmula:C22H29FN3O10P
    Cor e Forma:Solid
    Peso molecular:545.457
  • Urease-IN-2


    <p>Urease-IN-2 is a non-competitive inhibitor of urease (IC50: 0.94 μM, Ki: 1.6 μM) that non-competitively inhibits Jack bean urease (JBU).</p>
    Fórmula:C26H25N5O5S3
    Cor e Forma:Solid
    Peso molecular:583.7
  • Cap-dependent endonuclease-IN-6

    CAS:
    <p>Cap-dependent endonuclease-IN-6 (compound 13) is a Cap-dependent endonuclease (CEN) inhibitor that inhibits influenza virus.</p>
    Fórmula:C23H21N3O3S
    Cor e Forma:Solid
    Peso molecular:419.5
  • Anti-MRSA agent 3

    CAS:
    <p>Anti-MRSA agent 3 targets MRSA with 0.098 μg/ml MIC, low toxicity, binds DNA, and disrupts cell walls/membranes.</p>
    Fórmula:C29H18BrN3O2
    Cor e Forma:Solid
    Peso molecular:520.386
  • cis-RdRP-IN-5


    <p>Cis-RdRP-IN-5 is an effective inhibitor of the influenza virus RNA-dependent RNA polymerase (RdRP), employed in influenza virus research.</p>
    Fórmula:C23H21N3O5
    Cor e Forma:Solid
    Peso molecular:419.43
  • Artefenomel

    CAS:
    <p>Artefenomel (OZ439) is an orally active anti-malarial ozone analog with antiviral activity for the study of SARS-CoV-2 infections and malaria infections.</p>
    Fórmula:C28H39NO5
    Cor e Forma:Solid
    Peso molecular:469.61
  • BRN3OMe

    CAS:
    <p>BRN3OMe is an effective inhibitor of HIV-1 reverse transcriptase (HIV-1 reverse transcriptase), showing potential for antiviral drug research.</p>
    Fórmula:C7H13N3O4
    Cor e Forma:Solid
    Peso molecular:203.196
  • Gln-AMS TFA


    <p>Gln-AMS (TFA) is a type Ia amido-tRNA synthetase (AARS) inhibitor with a Ki value of 1.32 μM for glutaminyl-tRNA synthetase.</p>
    Fórmula:C17H23F3N8O10S
    Cor e Forma:Solid
    Peso molecular:588.47
  • Antitrypanosomal agent 5


    <p>Antitrypanosal agent 5 is a selective anti-trypanosomal agent that acts on T. brucei (IC50: 1 nM) and HEK293 cells (IC50: 483.3 μM).</p>
    Fórmula:C30H30N6O4S
    Cor e Forma:Solid
    Peso molecular:570.66
  • Zorubicin

    CAS:
    <p>Zorubicin, a Daunorubicin derivative, targets topoisomerase II, inhibits DNA polymerase, and researches acute leukemia, sarcomas.</p>
    Fórmula:C34H35N3O10
    Cor e Forma:Solid
    Peso molecular:645.66
  • RAD51-IN-5

    CAS:
    <p>RAD51-IN-5 blocks RAD51; may aid mitochondrial disorder research. (WO2021164746A1, cmpd 3)</p>
    Fórmula:C26H38N4O5S2
    Cor e Forma:Solid
    Peso molecular:550.73
  • Antibiofilm agent-4

    CAS:
    <p>Antibiofilm agent-4 is a LasR inhibitor, demonstrating optimal antibiofilm and anti-QS (quorum sensing) properties.</p>
    Fórmula:C15H15NO3
    Peso molecular:257.28
  • Antifungal agent 13

    CAS:
    <p>Antifungal agent 13 demonstrates significant antifungal activity against Sclerotinia sclerotiorum, achieving an EC50 of 1.25 mg/L.</p>
    Fórmula:C21H16ClF3N4O
    Cor e Forma:Solid
    Peso molecular:432.83
  • Cetefloxacin

    CAS:
    <p>Cetefloxacin (E 4868) is a broad-spectrum antibacterial antibiotic with a minimum inhibitory concentration (MIC) ranging from 0.007 to 8 µg/ml. In mice, cetefloxacin demonstrates favorable pharmacokinetic properties and provides protection against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Streptococcus pneumoniae.</p>
    Fórmula:C20H16F3N3O3
    Peso molecular:403.35
  • PptT-IN-2


    <p>PptT-IN-2 inhibits PptT enzyme crucial in tuberculosis, with 2.5 μM IC50, showing potential in TB research.</p>
    Fórmula:C22H29N5O2
    Cor e Forma:Solid
    Peso molecular:395.5
  • GC-78-HCl

    CAS:
    <p>GC-78-HCl is an orally active, non-peptidic SARS-CoV-2 Mpro inhibitor with an enzyme IC50 of 0.19 μM. It exhibits strong anti-coronavirus activity and favorable pharmacokinetic properties.</p>
    Fórmula:C25H25Cl3N4O4
    Peso molecular:551.85
  • AK-968-11563024

    CAS:
    <p>AK-968-11563024 is an inhibitor targeting marine V. vulnificus NAT [(VIBVN)NAT] with an IC50 value of 18.86 µM. In V. vulnificus, NAT (aromatic amine N-acetyltransferase) plays a role in drug metabolism, contributing to drug resistance. Thus, AK-968-11563024 can be used for research related to drug tolerance.</p>
    Fórmula:C18H13I2N9O5
    Cor e Forma:Solid
    Peso molecular:689.162
  • EFdA-TP tetrasodium

    CAS:
    <p>EFdA-TP tetrasodium is a potent HIV-1 inhibitor that blocks DNA synthesis as an ICT or DCT.</p>
    Fórmula:C12H11FN5Na4O12P3
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:621.12
  • Anti-MRSA agent 23

    CAS:
    <p>Anti-MRSA agent 23 (compound 11) is a potent agent against methicillin-resistant Staphylococcus aureus. This compound exhibits both antibacterial and antibiofilm properties. It facilitates the healing and reconstruction of MRSA-infected skin wounds by reducing bacterial load, alleviating inflammation, and promoting angiogenesis.</p>
    Fórmula:C20H17N5O3S
    Cor e Forma:Solid
    Peso molecular:407.446
  • ACSS2-IN-1

    CAS:
    <p>ACSS2-IN-1, a potent ACSS2 inhibitor, has IC50 0.01-&lt;1 nM; useful in cancer research.</p>
    Fórmula:C27H25ClN6O2
    Cor e Forma:Solid
    Peso molecular:500.98
  • ddCTP trisodium


    <p>ddCTP trisodium, an HIV reverse transcriptase target, aids AIDS research and DNA sequencing as a ddNTP.</p>
    Fórmula:C9H13N3Na3O12P3
    Cor e Forma:Solid
    Peso molecular:517.1
  • Chitin synthase inhibitor 1


    <p>Potent, selective CHS inhibitor with 0.12 mM IC50; effective against drug-resistant fungi.</p>
    Fórmula:C22H20ClN3O3
    Cor e Forma:Solid
    Peso molecular:409.87
  • Pks13-TE inhibitor 4

    CAS:
    <p>Pks13-TE inhibitor 4 (compound 44) is a potent inhibitor from the thiazole series that effectively targets Pks13 to combat tuberculosis (TB) and addresses drug resistance.</p>
    Fórmula:C26H25N5O6
    Peso molecular:503.51
  • Lapyrium chloride

    CAS:
    Lapyrium chloride (Emcol E 607) is a broad-spectrum antibacterial agent that serves as a preservative and disinfectant.
    Fórmula:C21H35ClN2O3
    Peso molecular:398.97
  • Diploicin

    CAS:
    <p>Diploicin is a dibenzofuran lactone compound with activity against Gram-positive bacteria, found in lichens (lichens).</p>
    Fórmula:C16H10Cl4O5
    Cor e Forma:Solid
    Peso molecular:424.06
  • RdRP-IN-5

    CAS:
    <p>RdRP-IN-5 (compound 20), a potent inhibitor of the influenza virus RNA-dependent RNA polymerase (RdRP), has potential application in influenza research [1].</p>
    Fórmula:C23H21N3O5
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:419.43
  • Griseofulvic Acid

    CAS:
    <p>Griseofulvic Acid ((±)-Griseofulvic acid) is a metabolite of the antifungal agent Griseofulvin. It induces protein aggregation and tubulin polymerization in cell-free assays.</p>
    Fórmula:C16H15ClO6
    Peso molecular:338.74
  • 7-APRA

    CAS:
    <p>7-APRA is a semisynthetic intermediate of the cephalosporin class of antibiotics. It exhibits antibacterial activity and is primarily used in the synthesis of other cephalosporin antibiotics, such as Cefaclor and Cefprozil.</p>
    Fórmula:C10H12N2O3S
    Peso molecular:240.28
  • GSK5852


    <p>GSK5852, an HCV NS5B inhibitor, has IC50 of 50 nM; potently fights HCV with EC50 of 3.0 nM for GT1a and 1.7 nM for GT1b.</p>
    Fórmula:C27H27BF2N2O6S
    Cor e Forma:Solid
    Peso molecular:556.39
  • AnCDA-IN-1

    CAS:
    <p>AnCDA-IN-1 (Compound J075-4187) is an inhibitor of chitin deacetylase (CDA) exhibiting antifungal properties. It possesses an IC50 of 4.24 μM against A. nidulans AnCDA. The compound demonstrates a minimum inhibitory concentration (MIC) of 260 μg/mL and a minimum fungicidal concentration (MFC) of 520 μg/mL for food spoilage fungi and plant pathogenic fungi. AnCDA-IN-1 is applicable for research in the antifungal domain.</p>
    Fórmula:C16H13ClN4O2
    Cor e Forma:Solid
    Peso molecular:328.753
  • HIV-1 inhibitor-44


    <p>HIV-1 inhibitor-44 (compound 11l) is an HIV-1 reverse transcriptase inhibitor that exhibits activity against wild-type HIV-1 strains (EC50: 0.209 μM).</p>
    Fórmula:C23H26N2O4S
    Cor e Forma:Solid
    Peso molecular:426.53
  • Cefempidone

    CAS:
    <p>Cefempidone (GR 50692) is a third-generation cephalosporin antibiotic. It exhibits antibacterial activity by inhibiting penicillin-binding proteins involved in the synthesis of bacterial cell walls.</p>
    Fórmula:C22H21N7O6S2
    Peso molecular:543.58
  • Antibacterial agent 259

    CAS:
    <p>Antibacterialagent 259 (K3) is a bactericide with EC50 values of 1.5, 1.7, and 4.9 mg/L against Xoo, Xoc, and Xac, respectively. It induces the production of reactive oxygen species (ROS) in pathogens, leading to their death. Antibacterialagent 259 is applicable in research for controlling bacterial diseases in plants.</p>
    Fórmula:C7H6ClN3O2S
    Cor e Forma:Solid
    Peso molecular:231.659