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Microbiologia/Virologia

Microbiologia/Virologia

Os inibidores de microbiologia e virologia são compostos que têm como alvo microrganismos, incluindo bactérias, vírus e fungos, interrompendo seu crescimento, replicação ou sobrevivência. Esses inibidores são essenciais para estudar a patogênese microbiana, entender os mecanismos de resistência e desenvolver novas terapias antimicrobianas e antivirais. Os inibidores nessa categoria são usados para combater doenças infecciosas, explorar a ecologia microbiana e investigar as interações hospedeiro-patógeno. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para microbiologia e virologia para apoiar sua pesquisa em doenças infecciosas, microbiologia e virologia.

Subcategorias de "Microbiologia/Virologia"

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Foram encontrados 5842 produtos de "Microbiologia/Virologia"

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  • Arterolane maleate

    CAS:
    <p>Arterolane, an adenosine triphosphatase inhibitor, is used potentially for the treatment of malaria.</p>
    Fórmula:C26H40N2O8
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:508.612
  • DL-2-Aminopimelic Acid

    CAS:
    <p>DL-2-Aminopimelic Acid acts as a weak agonist for glutamate receptors and also reduces the sensitivity of leech glutamate receptors to glutamate.</p>
    Fórmula:C7H13NO4
    Cor e Forma:Solid
    Peso molecular:175.18
  • DNDI-8219

    CAS:
    <p>DNDI-8219 is an antitubercular agent. It has potent antileishmanial effects.</p>
    Fórmula:C13H10F3N3O5
    Cor e Forma:Solid
    Peso molecular:345.23
  • GSK5852


    <p>GSK5852, an HCV NS5B inhibitor, has IC50 of 50 nM; potently fights HCV with EC50 of 3.0 nM for GT1a and 1.7 nM for GT1b.</p>
    Fórmula:C27H27BF2N2O6S
    Cor e Forma:Solid
    Peso molecular:556.39
  • (R)-ZG197


    <p>(R)-ZG197: Activates Sa ClpP (EC50=1.5μM) &amp; Hs ClpP (EC50=31.4μM); selective for Sa ClpP.</p>
    Fórmula:C28H35F3N4O3
    Cor e Forma:Solid
    Peso molecular:532.6
  • Chitin synthase inhibitor 1


    <p>Potent, selective CHS inhibitor with 0.12 mM IC50; effective against drug-resistant fungi.</p>
    Fórmula:C22H20ClN3O3
    Cor e Forma:Solid
    Peso molecular:409.87
  • KL-50

    CAS:
    <p>KL-50, a selective toxin, effectively targets tumors deficient in the DNA repair protein O6-methylguanine-DNA-methyltransferase (MGMT), which corrects O6-alkylguanine lesions. This compound induces both DNA damage response pathways and cell cycle arrest in MGMT-deficient cells, regardless of mismatch repair (MMR) status. KL-50 shows promise in the study of brain tumors lacking MGMT.</p>
    Fórmula:C7H7FN6O2
    Cor e Forma:Solid
    Peso molecular:226.17
  • MBX-1162

    CAS:
    <p>MBX-1162, a bis-indole compound, has demonstrated unique substrate specificity related to MepA and MepR in studies investigating its resistance mechanisms in Staphylococcus aureus. It has not shown cross-resistance with related compounds.</p>
    Fórmula:C30H28N6
    Cor e Forma:Solid
    Peso molecular:472.58
  • Diploicin

    CAS:
    <p>Diploicin is a dibenzofuran lactone compound with activity against Gram-positive bacteria, found in lichens (lichens).</p>
    Fórmula:C16H10Cl4O5
    Cor e Forma:Solid
    Peso molecular:424.06
  • NDM-1 inhibitor-5

    CAS:
    <p>NDM-1 Inhibitor-5 (compound 57) exhibits strong inhibition of NDM-1, characterized by a K i of 2.5 μM. Additionally, it demonstrates synergistic antibacterial effects when combined with meropenem [1].</p>
    Fórmula:C24H23NO4
    Cor e Forma:Solid
    Peso molecular:389.44
  • Antibacterial agent 259

    CAS:
    <p>Antibacterialagent 259 (K3) is a bactericide with EC50 values of 1.5, 1.7, and 4.9 mg/L against Xoo, Xoc, and Xac, respectively. It induces the production of reactive oxygen species (ROS) in pathogens, leading to their death. Antibacterialagent 259 is applicable in research for controlling bacterial diseases in plants.</p>
    Fórmula:C7H6ClN3O2S
    Cor e Forma:Solid
    Peso molecular:231.659
  • Isazofos

    CAS:
    <p>Isazofos is a broad-spectrum organophosphate insecticide and nematicide effective in controlling a variety of lawn pests, such as nematodes (Radopholus similis). It also demonstrates efficacy in managing rice gall midge.</p>
    Fórmula:C9H17ClN3O3PS
    Cor e Forma:Solid
    Peso molecular:313.74
  • Anti-MRSA agent 19

    CAS:
    <p>Anti-MRSA agent 19 (Compound 1) is an antibiotic that exhibits activity against Staphylococcus aureus. It is active against 40 clinical isolates from the CDC, representing diverse bacterial species with various resistance factors, including resistance to vancomycin, aminoglycoside/tetracycline, and oxazolidinone (median MIC=4 μg/mL).</p>
    Fórmula:C15H10Cl3NO4
    Cor e Forma:Solid
    Peso molecular:374.6
  • Cefempidone

    CAS:
    <p>Cefempidone (GR 50692) is a third-generation cephalosporin antibiotic. It exhibits antibacterial activity by inhibiting penicillin-binding proteins involved in the synthesis of bacterial cell walls.</p>
    Fórmula:C22H21N7O6S2
    Peso molecular:543.58
  • AV-5080

    CAS:
    <p>AV-5080 is an orally active neuraminidase (neuraminidase) inhibitor that is utilized in the research of both Type A and Type B influenza viruses.</p>
    Fórmula:C15H25FN4O4
    Cor e Forma:Solid
    Peso molecular:344.38
  • 20S Proteasome-IN-4

    CAS:
    <p>20S Proteasome-IN-4: brain-penetrant, parasite-specific, oral, inhibits T.b. brucei proteasome (IC50: 6.3nM), for HAT research.</p>
    Fórmula:C20H18ClF2N3O3
    Cor e Forma:Solid
    Peso molecular:421.83
  • SARS-CoV-2-IN-102

    CAS:
    <p>SARS-CoV-2-IN-102 (example 58) is an inhibitor of the SARS-CoV papain-like protease (SARS-CoVPLpro), demonstrating an IC50 of less than 100 nM.</p>
    Fórmula:C29H34F2N6O2
    Cor e Forma:Solid
    Peso molecular:536.62
  • Antibacterial agent 112


    <p>Compound 112: Powerful antibacterial, MIC 1250 μM against B. subtilis, E. coli, E. faecalis, S. typhimurium, S. aureus; also an HIV-1 antibody.</p>
    Fórmula:C35H23N5O5
    Cor e Forma:Solid
    Peso molecular:593.59
  • Menoctone

    CAS:
    <p>Menoctone is an orally effective antimalarial agent that inhibits blood-induced rodent malaria. It enhances the antimalarial effects of chloroquine or quinine, making it useful for malaria research.</p>
    Fórmula:C24H32O3
    Cor e Forma:Solid
    Peso molecular:368.51
  • MED6-189

    CAS:
    <p>MED6-189, an analog of kalihinol, disrupts the apicoplast functions and vesicular transport in the malignant malaria parasite (P. falciparum, IC50 &lt; 50 nM). The compound specifically targets the apicoplast, which is a non-photosynthetic plastid essential for isoprenoid synthesis, found in most apicomplexan parasites.</p>
    Fórmula:C17H26N2O
    Cor e Forma:Solid
    Peso molecular:274.40
  • Antibacterial agent 262

    CAS:
    <p>Antibacterialagent 262 (compound A23) is a potent antibacterial agent that inhibits the activity of Xanthomonas oryzae pv oryzae. It also disrupts the integrity of bacterial cell membranes by preventing the formation of biofilms of Xanthomonas oryzae pv oryzae.</p>
    Fórmula:C17H18F2N6O4S3
    Cor e Forma:Solid
    Peso molecular:504.554
  • FPI-1465

    CAS:
    <p>FPI-1465: Dual serine-β-lactamase &amp; PBP inhibitor; IC50 PBP2=1.0 μg/mL; Kd CTX-M-15=0.011μM, OXA-48=5.3μM.</p>
    Fórmula:C11H18N4O7S
    Cor e Forma:Solid
    Peso molecular:350.35
  • HT1171

    CAS:
    <p>HT1171 is a potent and selective inhibitor of the Mycobacterium tuberculosis proteasome. It exhibits strong antitubercular activity against Mycobacterium tuberculosis H37Rv, with a MIC90 of 2 μg/mL and MIC of 4 μg/mL. At a concentration of 100 μM, HT1171 shows an inhibition rate of 53.8% against normal human liver cells (L02). HT1171 is applicable in antituberculosis drug research.</p>
    Fórmula:C7H4N2O4S2
    Cor e Forma:Solid
    Peso molecular:244.248
  • 12(S)-HETE

    CAS:
    <p>Enpatoran hydrochloride (M5049 hydrochloride) is a TLR7/8 inhibitor with antiviral activity that is used in the study of autoimmune diseases.</p>
    Fórmula:C20H32O3
    Cor e Forma:Solid
    Peso molecular:320.47
  • Antibacterial agent 261

    CAS:
    <p>Antibacterialagent 261 (compound 43) is a potent inhibitor of the peptide deformylase (PDF) enzyme, demonstrating IC50 values of 2.5 nM against Staphylococcus aureus (S. aureus) and 10.6 nM against Escherichia coli (E. coli).</p>
    Fórmula:C18H24N4O3S2
    Cor e Forma:Solid
    Peso molecular:408.538
  • Chitin synthase inhibitor 8


    <p>Chitin synthase inhibitor 8 is a chitin synthase (CHS) inhibitor with broad-spectrum antifungal effects that can be used in studies related to fungal infections</p>
    Fórmula:C23H23N3O5
    Cor e Forma:Solid
    Peso molecular:421.45
  • Antifungal agent 42


    <p>Antifungal 42 blocks biofilm formation and inhibits C.albicans' CYP51.</p>
    Fórmula:C22H20Cl2N4Se2
    Cor e Forma:Solid
    Peso molecular:569.25
  • Fabimycin

    CAS:
    <p>Fabimycin, a FabI inhibitor, combats drug-resistant gram-negative bacterial infections effectively.</p>
    Fórmula:C23H25ClN4O3
    Cor e Forma:Solid
    Peso molecular:440.92
  • Antileishmanial agent-4


    <p>Antileishmanial agent-4, a ribonucleoside analogue, functions as an antileishmanial agent [1].</p>
    Fórmula:C17H18N4O4
    Cor e Forma:Solid
    Peso molecular:342.35
  • Anti-Influenza agent 3


    <p>Compound 11h: Potent, low-toxicity anti-influenza, inhibits M2 ion channels. EC50: 3.29μM (H3N2), 2.45μM (H1N1).</p>
    Fórmula:C16H22ClNOS
    Cor e Forma:Solid
    Peso molecular:311.87
  • Cap-dependent endonuclease-IN-14

    CAS:
    <p>Cap-dependent endonuclease-IN-14 hinders CEN and could treat influenza virus infections. (Patent CN113620948A, compound 1-c).</p>
    Fórmula:C30H23FN2O6S
    Cor e Forma:Solid
    Peso molecular:558.58
  • Doxazosin impurity 12

    CAS:
    <p>Doxazosin impurity 12 acts as an inhibitor of CTX-M β-lactamase (Beta-lactamase) with a Ki value of 0.7 mM against CTX-M.</p>
    Fórmula:C10H6O5S
    Cor e Forma:Solid
    Peso molecular:238.217
  • PCNA-IN-1

    CAS:
    <p>PCNA-IN-1 (Compound 11) is an inhibitor of the PCNA/PIP-box interaction, with an IC50 greater than 50 μM. It is applicable in cancer research.</p>
    Fórmula:C19H18I3NO3
    Cor e Forma:Solid
    Peso molecular:689.065
  • MDL-860

    CAS:
    <p>MDL-860 is a broad-spectrum antiviral compound targeting small RNA viruses and exhibits low cytotoxicity to human cells. MDL-860 is useful for research into viral infections.</p>
    Fórmula:C13H6Cl2N2O3
    Cor e Forma:Solid
    Peso molecular:309.104
  • Piperacillin hydrate

    CAS:
    <p>Piperacillin hydrate is a semisynthetic broad-spectrum β-lactam antibiotic. It exhibits potent bactericidal activity against Gram-negative bacteria and some Gram-positive bacteria by targeting penicillin-binding proteins. Piperacillin hydrate is frequently combined with the β-lactamase inhibitor Tazobactam for enhanced efficacy.</p>
    Fórmula:C23H29N5O8S
    Cor e Forma:Solid
    Peso molecular:535.57
  • Antifungal agent 127

    CAS:
    <p>Antifungalagent 127 (Compound 6c) is an antifungal agent with potent inhibitory activity against Botrytis cinerea and Rhizoctonia solani.</p>
    Fórmula:C13H12ClN3O
    Cor e Forma:Solid
    Peso molecular:261.707
  • Antileishmanial agent-5


    <p>Antileishmanial agent-4, a ribonucleoside analogue, targets L.infantum and T.cruzi with EC50s of 0.68 μM and 0.83 μM.</p>
    Fórmula:C17H17ClN4O4
    Cor e Forma:Solid
    Peso molecular:376.79
  • XR8-89

    CAS:
    <p>XR8-89, a potent PLpro inhibitor (IC50=0.1μM), blocks SARS-CoV-2 replication; useful for research.</p>
    Fórmula:C29H36N4O2S
    Cor e Forma:Solid
    Peso molecular:504.69
  • Thiolactomycin

    CAS:
    <p>Thiolactomycin is a novel reversible dual inhibitor of D-amino acid oxidase (DAO) and D-Aspartate oxidase (DDO).</p>
    Fórmula:C11H14O2S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:210.29
  • Diclosulam

    CAS:
    <p>Diclosulam (XDE 564) is an herbicide with a Ki value of less than 32 nM. It exhibits a MIC of 6.25 and 12.5 μM, and a MIC50 of 1.40 and 3.01 μM against the CBS10913 and CBS12373 strains, respectively.</p>
    Fórmula:C13H10Cl2FN5O3S
    Cor e Forma:Solid
    Peso molecular:406.22
  • Rubropunctatin

    CAS:
    <p>Rubropunctatin is a monascus pigment with very potent cancer cell proliferation inhibitory effects.</p>
    Fórmula:C21H23NO4
    Cor e Forma:Solid
    Peso molecular:353.41
  • Antimicrobial agent-38

    CAS:
    <p>Antimicrobial agent-38 (compound 10) effectively inhibits methicillin-resistant Staphylococcus aureus (S. aureus) strain ATCC 700699 and non-resistant strain ATCC 29213, with minimum inhibitory concentrations (MIC) of 32 mg/L and 64 mg/L, respectively.</p>
    Fórmula:C14H11N3O4S
    Cor e Forma:Solid
    Peso molecular:317.32
  • SMCypI C31


    <p>SMCypIC31, a non-peptide cyclophilin inhibitor, blocks PPIase at 0.1 μM IC50 and fights various HCV genotypes (EC50: 1.20-7.76 μM).</p>
    Fórmula:C27H30N4O2S
    Cor e Forma:Solid
    Peso molecular:474.62
  • DENV-IN-6

    CAS:
    <p>DENV-IN-6, a potent anti-DENV (I-IV) and HIV-1 IIIB inhibitor with EC50 ranging 6.8-17.5 μM for DENV and EC50 0.0181 μM for HIV-1.</p>
    Fórmula:C23H26ClFN4OS
    Cor e Forma:Solid
    Peso molecular:461
  • Elongation factor P-IN-2


    <p>Elongation factor P-IN-2, a β-lysine derivative, is a potent EFP inhibitor reducing E. coli growth.</p>
    Fórmula:C16H35N3O2
    Cor e Forma:Solid
    Peso molecular:301.47
  • RdRP-IN-4


    <p>RdRP-IN-4, an oral arylbenzohydrazide, inhibits influenza A/B by targeting PB1 of RdRP, with EC50s of 53 nM (H1N1) and 20 nM (Flu B), and aids infected mice.</p>
    Fórmula:C17H17Br2N3O2
    Cor e Forma:Solid
    Peso molecular:455.14
  • PqsR-IN-1


    <p>PqsR-IN-1, potent PqsR inhibitor, curbs pyocyanin in Pseudomonas aeruginosa with low cytotoxicity.</p>
    Fórmula:C17H18ClN3OS
    Cor e Forma:Solid
    Peso molecular:347.86
  • FGI-106

    CAS:
    <p>FGI-106 combats Ebola, Rift Valley, Dengue Fever, HCV, and HIV-1; EC50s range from 100-900 nM.</p>
    Fórmula:C28H38N6
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:458.64
  • Teslexivir hydrochloride

    CAS:
    <p>Teslexivir (BTA074) HCl inhibits HPV 6/11 by blocking E1-E2 protein interaction, vital for DNA replication. Used in condyloma research.</p>
    Fórmula:C35H37BrClN3O4
    Cor e Forma:Solid
    Peso molecular:679.04
  • (Z)-Lanoconazole


    <p>(Z)-Lanoconazole, an imidazole antifungal for dermatophytosis and onychomycosis, inhibits fungal ergosterol production.</p>
    Fórmula:C14H10ClN3S2
    Cor e Forma:Solid
    Peso molecular:319.83