Microbiologia/Virologia
Os inibidores de microbiologia e virologia são compostos que têm como alvo microrganismos, incluindo bactérias, vírus e fungos, interrompendo seu crescimento, replicação ou sobrevivência. Esses inibidores são essenciais para estudar a patogênese microbiana, entender os mecanismos de resistência e desenvolver novas terapias antimicrobianas e antivirais. Os inibidores nessa categoria são usados para combater doenças infecciosas, explorar a ecologia microbiana e investigar as interações hospedeiro-patógeno. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para microbiologia e virologia para apoiar sua pesquisa em doenças infecciosas, microbiologia e virologia.
Subcategorias de "Microbiologia/Virologia"
- Antibacteriano(2.949 produtos)
- Antibiótico(919 produtos)
- Antifecção(23 produtos)
- DHFR(32 produtos)
- Síntese de DNA/RNA(707 produtos)
- HBV(176 produtos)
- HIV Protease(447 produtos)
- HSV(91 produtos)
- Integrase(2 produtos)
- Ribossomo(13 produtos)
Exibir 2 mais subcategorias
Foram encontrados 5832 produtos de "Microbiologia/Virologia"
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WQ3810 TFA
<p>WQ3810 TFA is an orally available fluoroquinolone with antimicrobial activity against Mycobacterium tuberculosis and inhibits the DNA rotamase activity of</p>Fórmula:C24H23F6N5O5Pureza:99.52%Cor e Forma:SoildPeso molecular:575.46Ipronidazole
CAS:<p>Ipronidazole (RO-71554) is an orally effective antiprotozoal agent used to prevent and ameliorate histomoniasis in turkeys, commonly referred to as blackhead disease.</p>Fórmula:C7H11N3O2Cor e Forma:SolidPeso molecular:169.18Pibrozelesin
CAS:<p>Pibrozelesin, a water-soluble duocarmycin B2 derivative, binds AT-rich DNA, blocking replication and inducing cell death.</p>Fórmula:C32H36BrN5O8Cor e Forma:SolidPeso molecular:698.56SARS-CoV-2 PLpro-IN-1
CAS:<p>SARS-CoV-2 PLpro-IN-1 (Compound 85) is a non-covalent competitive inhibitor of SARS-CoV-2 PLpro with an IC50 value of 15.06 μM and a Ki value of 22.93 μM. It inhibits the proliferation of Vero cells, exhibiting an IC50 of 7.47 μM.</p>Fórmula:C18H19N5OCor e Forma:SolidPeso molecular:321.376Arterolane maleate
CAS:<p>Arterolane, an adenosine triphosphatase inhibitor, is used potentially for the treatment of malaria.</p>Fórmula:C26H40N2O8Pureza:98%Cor e Forma:SolidPeso molecular:508.612Chitin synthase inhibitor 8
<p>Chitin synthase inhibitor 8 is a chitin synthase (CHS) inhibitor with broad-spectrum antifungal effects that can be used in studies related to fungal infections</p>Fórmula:C23H23N3O5Cor e Forma:SolidPeso molecular:421.45Metallo-β-lactamase-IN-14
CAS:<p>Metallo-β-lactamase-IN-14 (Compound 17e) serves as an inhibitor of Metallo-β-Lactamase, displaying inhibitory activity against VIM-1 and VIM-2. This compound also exhibits antibacterial effects on Gram-negative (GN) bacteria and P. aeruginosa [1].</p>Fórmula:C20H22N8O2S2Cor e Forma:SolidPeso molecular:470.57Flutimide
CAS:<p>Flutimide: Endonuclease inhibitor, IC50 = 3μM, for research on acute respiratory diseases like influenza.</p>Fórmula:C12H18N2O3Cor e Forma:SolidPeso molecular:238.28PqsR-IN-2
<p>PqsR-IN-2, potent PqsR inhibitor, curbs Pseudomonas aeruginosa communication, reduces pyocyanin, with low toxicity.</p>Fórmula:C18H20ClN3OSCor e Forma:SolidPeso molecular:361.89RAD51-IN-5
CAS:<p>RAD51-IN-5 blocks RAD51; may aid mitochondrial disorder research. (WO2021164746A1, cmpd 3)</p>Fórmula:C26H38N4O5S2Cor e Forma:SolidPeso molecular:550.73ZINC000104379474
<p>ZINC000104379474 is a compound that targets SARS-CoV-2 endoribonuclease.</p>Fórmula:C27H33N3O10Cor e Forma:SolidPeso molecular:559.57BI-2540
CAS:<p>BI-2540 is a HIV non-nucleoside reverse transcriptase ( NNRT ) inhibitor .</p>Fórmula:C24H15ClF5NO5Cor e Forma:SolidPeso molecular:527.83Anti-MRSA agent 23
CAS:<p>Anti-MRSA agent 23 (compound 11) is a potent agent against methicillin-resistant Staphylococcus aureus. This compound exhibits both antibacterial and antibiofilm properties. It facilitates the healing and reconstruction of MRSA-infected skin wounds by reducing bacterial load, alleviating inflammation, and promoting angiogenesis.</p>Fórmula:C20H17N5O3SCor e Forma:SolidPeso molecular:407.446GS-9822
CAS:<p>GS-9822 is a new LEDGIN inhibitor targeting LEDGF/p75 to alter HIV integration, showing a block-and-lock effect in cells.</p>Fórmula:C36H39ClN4O4SCor e Forma:SolidPeso molecular:659.24HBV-IN-12
CAS:<p>HBV-IN-12: strong HBsAg & HBV DNA inhibitor; EC50 0.001-0.05 μM & 0.001-0.02 μM respectively. (WO2021204252A1)</p>Fórmula:C23H27NO8Cor e Forma:SolidPeso molecular:445.46Glutamate-5-kinase-IN-1
<p>Glutamate-5-kinase-IN-1 is a potent G5K inhibitor with a 4.1 μM MIC, showing promise in anti-TB research.</p>Fórmula:C20H18N2OCor e Forma:SolidPeso molecular:302.37KL-50
CAS:<p>KL-50, a selective toxin, effectively targets tumors deficient in the DNA repair protein O6-methylguanine-DNA-methyltransferase (MGMT), which corrects O6-alkylguanine lesions. This compound induces both DNA damage response pathways and cell cycle arrest in MGMT-deficient cells, regardless of mismatch repair (MMR) status. KL-50 shows promise in the study of brain tumors lacking MGMT.</p>Fórmula:C7H7FN6O2Cor e Forma:SolidPeso molecular:226.17DNDI-8219
CAS:<p>DNDI-8219 is an antitubercular agent. It has potent antileishmanial effects.</p>Fórmula:C13H10F3N3O5Cor e Forma:SolidPeso molecular:345.23ddCTP trisodium
<p>ddCTP trisodium, an HIV reverse transcriptase target, aids AIDS research and DNA sequencing as a ddNTP.</p>Fórmula:C9H13N3Na3O12P3Cor e Forma:SolidPeso molecular:517.1RAD51-IN-6
CAS:<p>RAD51-IN-6, a potent RAD51 gene inhibitor, may help research mitochondrial disorders. (WO2021164746A1, cmpd 23)</p>Fórmula:C27H40N3O5PSCor e Forma:SolidPeso molecular:549.66Bersiporocin
CAS:<p>Bersiporocin is a novel prolyl-tRNA synthetase (PRS) inhibitor that exerts antifibrotic effects through downregulation of collagen synthesis in IPF.</p>Fórmula:C15H19Cl2N3OPureza:98.88% - 99.79%Cor e Forma:SolidPeso molecular:328.24epi-D-Captopril
CAS:<p>epi-D-Captopril (epi-D-SQ 14225) is a stereoisomer of Captopril and functions as an inhibitor of metallo-beta-lactamases (MBLs). The IC50 values of epi-D-Captopril for NDM-1, IMP-1, and VIM-2 are 64 μM, 173 μM, and 5.5 μM, respectively. This compound holds potential for research in MBLs-related antibiotic-resistant infections.</p>Fórmula:C9H15NO3SCor e Forma:SolidPeso molecular:217.285Polθ-IN-6
CAS:<p>Polθ-IN-6 (Compound 89) is an inhibitor of DNA polymerase theta (Polθ) and exhibits antitumor activity.</p>Fórmula:C25H23N3O3SCor e Forma:SolidPeso molecular:445.53Thiolactomycin
CAS:<p>Thiolactomycin is a novel reversible dual inhibitor of D-amino acid oxidase (DAO) and D-Aspartate oxidase (DDO).</p>Fórmula:C11H14O2SPureza:98%Cor e Forma:SolidPeso molecular:210.29MBX-1162
CAS:<p>MBX-1162, a bis-indole compound, has demonstrated unique substrate specificity related to MepA and MepR in studies investigating its resistance mechanisms in Staphylococcus aureus. It has not shown cross-resistance with related compounds.</p>Fórmula:C30H28N6Cor e Forma:SolidPeso molecular:472.58Lentiginosine
CAS:<p>Lentiginosine is a selective amyloglucosidase inhibitor.</p>Fórmula:C8H15NO2Cor e Forma:SolidPeso molecular:157.21Antibacterial agent 88
<p>Antibacterial agent 88 is an effective antibacterial agent against B. subtilis (MIC: 4 μg/ml) with MIC values of ≤0.0156 μg/mL for MRSA, MRSE and S. aureus.</p>Fórmula:C31H44N2O6SCor e Forma:SolidPeso molecular:572.76WRN inhibitor 12
CAS:WRN inhibitor 12 (compound 5) serves as an inhibitor for the WRN helicase.Fórmula:C33H33ClF3N9O5Cor e Forma:SolidPeso molecular:728.12PIQ-2
CAS:PIQ-2 (compound 54) serves as an antiprotozoal agent, displaying potent activity against IP. falciparum 3D7 and B. divergens Rouen, with IC50 values of 9.4 nM and 1.6 nM, respectively.Fórmula:C23H21F3N4O3Cor e Forma:SolidPeso molecular:458.43Antifungal agent 43
<p>Antifungal agent 43 inhibits biofilms with low toxicity to human cancer cells.</p>Fórmula:C24H26N4Se2Cor e Forma:SolidPeso molecular:528.41Benzisothiazolone
CAS:<p>Benzisothiazolone is an isothiazolinone fungicide that demonstrates growth inhibitory activity against Escherichia coli ATCC 8739 and yeast NCYC 1354. It is utilized in studies investigating growth inhibition models.</p>Fórmula:C7H5NOSCor e Forma:SolidPeso molecular:151.19N-Cbz-L-Cysteine
CAS:<p>N-Cbz-L-Cysteine (Cbz-cysteine) (compound 5) functions as a potent inhibitor of β-lactamase II, exhibiting a K i value of 97 µM [1].</p>Fórmula:C11H13NO4SCor e Forma:SolidPeso molecular:255.29Neuraminidase-IN-18
CAS:<p>Neuraminidase-IN-18 (compound N5), a novel polyheterocyclic neuraminidase (NA) inhibitor, demonstrates significant inhibitory activity against H5N1 NA, with an IC 50 of 0.14 μM against the wild-type H5N1 NA and 0.27 μM against the H5N1-H274Y mutant NA. This compound effectively binds to NAs, inhibiting influenza virus replication at the cellular level [1].</p>Fórmula:C22H18FN3O3SCor e Forma:SolidPeso molecular:423.46Pneumolysin-IN-1
CAS:<p>Pneumolysin-IN-1 (compound PB-3), characterized as a targeted small molecule inhibitor of Pneumolysin (PLY) with an IC50 value of 3.1 µM, acts as a pore-blocking agent and an anti-virulence factor. This compound is useful for researching infections caused by Streptococcus pneumoniae [1].</p>Fórmula:C23H16Cl2N2O4Cor e Forma:SolidPeso molecular:455.29HIV-1 inhibitor-52
CAS:<p>HIV-1 inhibitor-52: potent, broad-spectrum with EC50s 1.6-6.4 nM against various HIV-1 strains.</p>Fórmula:C46H72FNO5SCor e Forma:SolidPeso molecular:770.13Chitin synthase inhibitor 9
<p>CHS inhibitor 9: a broad-spectrum antifungal for studying fungal infections.</p>Fórmula:C24H25N3O6Cor e Forma:SolidPeso molecular:451.47Antifungal agent 100
CAS:<p>Antifungal agent 100 (compound 3i) demonstrates notable antifungal activity, exhibiting an EC 50 of 0.33 mg/L against S. sclerotiorum. It also possesses an IC 50 value of 0.63 mg/mL targeting the Succinate dehydrogenase (SDH) of the same organism [1].</p>Fórmula:C23H21N3O4SCor e Forma:SolidPeso molecular:435.5HKI12134085
CAS:<p>HKI12134085 (compound 3), an orally administered nitrobenzothiazinone (BTZ) derivative, demonstrates antibacterial efficacy against Mycobacterium tuberculosis. This compound exhibits significant in vivo inhibitory potency within a BALB/c mouse model of Mycobacterium tuberculosis infection [1].</p>Fórmula:C18H18F3N3O5SCor e Forma:SolidPeso molecular:445.41DNA crosslinker 6
CAS:<p>DNA crosslinker 6 (compound 1) is an anti-mitotic agent known for its strong binding affinity to AT-DNA and inhibition of AT-hook 1 binding to DNA (IC50=0.03 µM). Additionally, it exhibits anti-protozoal activity, effectively inhibiting T. brucei with an EC50 of 0.83 µM.</p>Fórmula:C19H21N7OCor e Forma:SolidPeso molecular:363.42Dioxidine
CAS:<p>Dioxidine is an antimicrobial agent that can inhibit bacterial growth. It is utilized in research on pyogenic infections.</p>Fórmula:C10H10N2O4Cor e Forma:SolidPeso molecular:222.197Antifungal agent 40
<p>Antifungal agent 40 blocks C. albicans CYP51 in pocket II, hindering lanosterol demethylase and biofilm growth.</p>Fórmula:C22H20Cl2N4SeCor e Forma:SolidPeso molecular:490.29Narlaprevir
CAS:<p>Narlaprevir (SCH 900518) is an HCV NS3 inhibitor with anti-HCV activity, inhibiting SARS-CoV-2, and useful in virus infection research.</p>Fórmula:C36H61N5O7SPureza:98%Cor e Forma:SolidPeso molecular:707.96Erythromycin B
CAS:<p>Erythromycin B exhibits antimalarial activity by effectively inhibiting the asexual growth of Plasmodium falciparum.</p>Fórmula:C37H67NO12Cor e Forma:SolidPeso molecular:717.93Ac-Atovaquone
CAS:<p>Ac-Atovaquone, an ester-acetylated derivative of atovaquone, acts as a potent inhibitor of cytochrome bc1 (cytochrome bc1). This compound shows potential for use in malaria research.</p>Fórmula:C24H21ClO4Cor e Forma:SolidPeso molecular:408.87Plm IV inhibitor-2
CAS:<p>"Plm IV inhibitor-2: Potent for Plm IV (IC50=24nM), affects Plm II/Plm I; malaria research compound."</p>Fórmula:C39H54N4O4Cor e Forma:SolidPeso molecular:642.87Antibacterial agent 87
<p>Antibacterial agent 87 is an effective antibacterial agent that acts on MRSA (MIC: 0.125 μg/ml), MRSE (MIC: 0.0625 μg/ml) and S. aureus (MIC: 0.0625 μg/ml).</p>Fórmula:C31H46N2O6SCor e Forma:SolidPeso molecular:574.77SARS-CoV-2-IN-80
CAS:<p>SARS-CoV-2-IN-80 (compound 13), identified as a potent inhibitor of SARS-CoV-2 3CLpro, exhibits an IC50 value of 0.964 µM [1].</p>Fórmula:C16H10O2SCor e Forma:SolidPeso molecular:266.31Polθ-IN-5
CAS:<p>Polθ-IN-5 (Compound 139) is an inhibitor of DNA polymerase theta (Polθ) that exhibits antitumor activity.</p>Fórmula:C23H18ClF2N7O3SCor e Forma:SolidPeso molecular:545.95Antibacterial agent 99
CAS:<p>Compound 7b (Antibacterial agent 99) is an effective agent with antibacterial, antifungal properties and no haemolytic activity.</p>Fórmula:C27H27BrN2Cor e Forma:SolidPeso molecular:459.42Gallinamide A
CAS:<p>Gallinamide A is a potent inhibitor of cathepsin L with an IC 50 value of 17.6 pM.</p>Fórmula:C31H52N4O7Cor e Forma:SolidPeso molecular:592.77
