Microbiologia/Virologia
Os inibidores de microbiologia e virologia são compostos que têm como alvo microrganismos, incluindo bactérias, vírus e fungos, interrompendo seu crescimento, replicação ou sobrevivência. Esses inibidores são essenciais para estudar a patogênese microbiana, entender os mecanismos de resistência e desenvolver novas terapias antimicrobianas e antivirais. Os inibidores nessa categoria são usados para combater doenças infecciosas, explorar a ecologia microbiana e investigar as interações hospedeiro-patógeno. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para microbiologia e virologia para apoiar sua pesquisa em doenças infecciosas, microbiologia e virologia.
Subcategorias de "Microbiologia/Virologia"
- Antibacteriano(3.207 produtos)
- Antibiótico(935 produtos)
- Antifecção(24 produtos)
- DHFR(34 produtos)
- Síntese de DNA/RNA(777 produtos)
- HBV(186 produtos)
- HIV Protease(489 produtos)
- HSV(94 produtos)
- Integrase(2 produtos)
- Ribossomo(13 produtos)
Exibir 2 mais subcategorias
Foram encontrados 6235 produtos de "Microbiologia/Virologia"
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ZLM-66
<p>ZLM-66: Doravirine analog, HIV-1 NNRTI inhibitor, IC50: 41nM, EC50: HIV-1 13nM, cIAP1 0.32nM; useful in AIDS research.</p>Cor e Forma:SolidAntitrypanosomal agent 5
Antitrypanosal agent 5 is a selective anti-trypanosomal agent that acts on T. brucei (IC50: 1 nM) and HEK293 cells (IC50: 483.3 μM).Fórmula:C30H30N6O4SCor e Forma:SolidPeso molecular:570.66AYK004-C1
CAS:AYK004-C1 is a TLR agonist used in the formulation of immunological adjuvants.Fórmula:C35H58F3N7O3Peso molecular:681.88HIV-1 inhibitor-41
HIV-1 inhibitor-41 (B23): Oral non-nucleoside reverse transcriptase blocker, EC50 of 50 nM (E138K), 20.8 nM (WT), low hERG/CYP impact, non-toxic.Fórmula:C16H15F2N3OSCor e Forma:SolidPeso molecular:335.37Werner syndrome RecQ helicase-IN-2
CAS:Werner syndrome RecQ helicase-IN-2 is a potent Werner syndrome RecQ DNA helicase (WRN) inhibitor, useful in research on colorectal and gastric cancers.Fórmula:C32H34F3N9O5Pureza:99.02%Cor e Forma:SolidPeso molecular:681.67N6-Benzoyl-2'-deoxyadenosine monohydrate
CAS:<p>N6-Benzoyl-2'-deoxyadenosine monohydrate is a nucleoside analogue that helps diagnose bacterial infections by binding to double-stranded DNA and altering its structure, which can subsequently be detected using electrophoresis.</p>Fórmula:C17H19N5O5Cor e Forma:SolidPeso molecular:373.363RdRP-IN-4
RdRP-IN-4, an oral arylbenzohydrazide, inhibits influenza A/B by targeting PB1 of RdRP, with EC50s of 53 nM (H1N1) and 20 nM (Flu B), and aids infected mice.Fórmula:C17H17Br2N3O2Cor e Forma:SolidPeso molecular:455.14HIV-1 inhibitor-82
CAS:HIV-1inhibitor-82 (Compound L14) is a small molecule inhibitor of HIV-1 entry with oral bioavailability, exhibiting an IC50 value of 0.39 μM. It holds potential for research in combating HIV-1 infection.Fórmula:C37H37ClN2O6S2Peso molecular:705.28HBV-IN-12
CAS:HBV-IN-12: strong HBsAg & HBV DNA inhibitor; EC50 0.001-0.05 μM & 0.001-0.02 μM respectively. (WO2021204252A1)Fórmula:C23H27NO8Cor e Forma:SolidPeso molecular:445.46Glutamate-5-kinase-IN-1
Glutamate-5-kinase-IN-1 is a potent G5K inhibitor with a 4.1 μM MIC, showing promise in anti-TB research.Fórmula:C20H18N2OCor e Forma:SolidPeso molecular:302.37AVE-1330A sodium
CAS:AVE-1330A sodium is a beta-Lactamase inhibitor.Fórmula:C7H10N3NaO6SCor e Forma:SolidPeso molecular:287.23Gallinamide A
CAS:Gallinamide A is a potent inhibitor of cathepsin L with an IC 50 value of 17.6 pM.Fórmula:C31H52N4O7Cor e Forma:SolidPeso molecular:592.77MDL-860
CAS:<p>MDL-860 is a broad-spectrum antiviral compound targeting small RNA viruses and exhibits low cytotoxicity to human cells. MDL-860 is useful for research into viral infections.</p>Fórmula:C13H6Cl2N2O3Cor e Forma:SolidPeso molecular:309.104HBV-IN-31
CAS:HBV-IN-31: strong cccDNA inhibitor, anti-HBV, IC50=0.13 µM HBsAg, hampers cell growth.Fórmula:C23H18ClNO6Cor e Forma:SolidPeso molecular:439.85Benzohydroxamic acid
CAS:Benzohydroxamic acid (BHA) is a chitin deacetylase (CDA) inhibitor with notable antifungal properties. It displays Ki values of 8.31 μM against Verticillium dahliae CDA and 9.83 μM against Puccinia striiformis f. sp. tritici CDA. BHA can restore the defense responses in infected host plants by upregulating the expression of defense-related genes, thereby reducing fungal growth and proliferation within the plants. It is applicable in the research of agricultural fungal diseases, such as cotton wilt and wheat stripe rust, caused by pathogens like Verticillium dahliae and Puccinia striiformis.Fórmula:C7H7NO2Cor e Forma:SolidPeso molecular:137.136TAN-1057C
CAS:TAN-1057C is a potent antibiotic with antimicrobial activity against both Gram-negative and Gram-positive bacteria, including Methicillin-resistant Staphylococcus aureus (MRSA).Fórmula:C13H25N9O3Cor e Forma:SolidPeso molecular:355.4cis-RdRP-IN-5
Cis-RdRP-IN-5 is an effective inhibitor of the influenza virus RNA-dependent RNA polymerase (RdRP), employed in influenza virus research.Fórmula:C23H21N3O5Cor e Forma:SolidPeso molecular:419.43Cap-dependent endonuclease-IN-5
CAS:Cap-dependent endonuclease-IN-5 inhibits CEN and fights influenza with low toxicity and good in vivo properties.Fórmula:C27H21F2N3O4S2Cor e Forma:SolidPeso molecular:553.60Adafosbuvir
CAS:Adafosbuvir has antiviral activity.Fórmula:C22H29FN3O10PCor e Forma:SolidPeso molecular:545.457Cap-dependent endonuclease-IN-6
CAS:Cap-dependent endonuclease-IN-6 (compound 13) is a Cap-dependent endonuclease (CEN) inhibitor that inhibits influenza virus.Fórmula:C23H21N3O3SCor e Forma:SolidPeso molecular:419.5Antitumor agent-75
Antitumor agent-75 is a novel and potent antitumor agent.Fórmula:C26H23FN6Cor e Forma:SolidPeso molecular:438.5AK-968-11563024
CAS:<p>AK-968-11563024 is an inhibitor targeting marine V. vulnificus NAT [(VIBVN)NAT] with an IC50 value of 18.86 µM. In V. vulnificus, NAT (aromatic amine N-acetyltransferase) plays a role in drug metabolism, contributing to drug resistance. Thus, AK-968-11563024 can be used for research related to drug tolerance.</p>Fórmula:C18H13I2N9O5Cor e Forma:SolidPeso molecular:689.162Rubropunctatin
CAS:Rubropunctatin is a monascus pigment with very potent cancer cell proliferation inhibitory effects.Fórmula:C21H23NO4Cor e Forma:SolidPeso molecular:353.41LN-439A
CAS:<p>LN-439A (compound LN-439A) is a novel BAP1 inhibitor that suppresses the growth of basal-like breast cancer by degrading KLF5.</p>Fórmula:C24H26FN3O4Cor e Forma:SolidPeso molecular:439.48Antiviral agent 7
Antiviral agent 7 is a peptide-based coating that kills viruses.Fórmula:C29H31F2N3O6Cor e Forma:SolidPeso molecular:555.574-Chloropyridine
CAS:4-Chloropyridine acts as an inhibitor of Nicotinamide N-methyltransferase (NNMT). Serving as a substrate for NNMT, this compound enhances the electrophilicity at the C4 position through methylation of the pyridine nitrogen. This modification facilitates an aromatic nucleophilic substitution reaction with the non-catalytic cysteine (C159) in NNMT, ultimately leading to suicidal activity inhibition of the enzyme. 4-Chloropyridine is a promising candidate for the development of activity-based probes targeting NNMT functions.Fórmula:C5H4ClNCor e Forma:SolidPeso molecular:113.55L-2'-Fd4C
CAS:L-2'-Fd4C is an L-nucleoside analogue with both anti-human immunodeficiency virus (HIV) and anti-hepatitis B virus (HBV) activity [1].Fórmula:C9H10FN3O3Cor e Forma:SolidPeso molecular:227.19SARS-CoV-2-IN-8
SARS-CoV-2-IN-8 is a major protease inhibitor of SARS-CoV-2 (IC50: 0.75 μM).Fórmula:C35H38N6O3Cor e Forma:SolidPeso molecular:590.71Antibacterial agent 281
CAS:Antibacterialagent 281 (Compound 95,186) effectively inhibits the growth of GAS by binding to the ligand-binding pocket of SPs0871, competing with the ligand. It exhibits concentration-dependent growth inhibition against Streptococcus pyogenes (S. pyogenes).Fórmula:C23H24N6OCor e Forma:SolidPeso molecular:400.48Antibacterial agent 113
Antibacterial agent 113 targets multiple bacteria including P. aeruginosa and E. coli, showing efficacy at MIC 15625 μM.Fórmula:C29H18ClN5OCor e Forma:SolidPeso molecular:487.94Thiolactomycin
CAS:Thiolactomycin is a novel reversible dual inhibitor of D-amino acid oxidase (DAO) and D-Aspartate oxidase (DDO).Fórmula:C11H14O2SPureza:98%Cor e Forma:SolidPeso molecular:210.29PqsR-IN-2
PqsR-IN-2, potent PqsR inhibitor, curbs Pseudomonas aeruginosa communication, reduces pyocyanin, with low toxicity.Fórmula:C18H20ClN3OSCor e Forma:SolidPeso molecular:361.89JPL
CAS:JPL is an InhA-cofactor-ligand 3FNG inhibitor and is used for the study of tuberculosis [1].Fórmula:C19H20Cl2O2Cor e Forma:SolidPeso molecular:351.27Antitubercular agent-11
Antitubercular agent-11 (Compound 1e) is an antitubercular agent with a bulkier electron-donating group (Bu-t) that shows the best MIC value of 0.060 μg/mL [1].Fórmula:C16H15N3O4Cor e Forma:SolidPeso molecular:313.31Gougerotin
CAS:Gougerotin is an inhibitor of protein synthesis.Fórmula:C16H25N7O8Cor e Forma:SolidPeso molecular:443.41Trypanothione synthetase-IN-4
Trypanothione synthetase-IN-4, an L. infantum inhibitor, has potent anti-leishmanicidal properties (EC50: 0.6 μM).Fórmula:C29H52INO2Cor e Forma:SolidPeso molecular:573.63InhA-IN-7
CAS:<p>InhA-IN-7 (Compound 11), a derivative of Triclocan, shows inhibitory activity against enoyl-acyl carrier protein reductase (InhA) with an IC50 of 96 nM. It effectively inhibits the proliferation of both wildtype and mutant strains of Mycobacterium tuberculosis, exhibiting minimum inhibitory concentrations (MICs) ranging from 19 to 75 μM [1].</p>Fórmula:C17H18Cl2O2Cor e Forma:SolidPeso molecular:325.23BPR3P0128
CAS:BPR3P0128, a non-nucleoside RNA-dependent RNA polymerase (RdRp) inhibitor, is effective orally and can inhibit various SARS-CoV-2 variants. It exhibits EC 50 values of 0.62 µM for SARS-CoV-2 and 0.14 µM for HCoV-229E, demonstrating potent anti-pancoronavirus activity at submicromolar concentrations. Additionally, BPR3P0128 displays synergistic antiviral effects when used in combination with Remdesivir [1].Fórmula:C22H18BrN3O2Cor e Forma:SolidPeso molecular:436.30CMX990
CAS:CMX990, a SARS-CoV-2 3CL protease inhibitor, exhibits EC90 values of 9.6 nM in human bronchial epithelial cells (HBECs) and 101 nM in HeLa-ACE2 cells. It also demonstrates good ADME and pharmacokinetic properties [1].Fórmula:C22H32F3N3O6Cor e Forma:SolidPeso molecular:491.50HBV/HDV-IN-3
CAS:<p>HBV/HDV-IN-3 (Compd 1) acts as a dual inhibitor for HBV and HDV, demonstrating an efficacy (EC 50) below 50 nM against HBV .</p>Fórmula:C28H27BrF3N5O3Cor e Forma:SolidPeso molecular:618.44Antimicrobial agent-29
CAS:Antimicrobial Agent-29 (Compound C35) influences the interaction between human hemoglobin and the Staphylococcus aureus IsdB hemophore. This compound facilitates the identification of IsdB:Hb PPI inhibitors [1].Fórmula:C19H14N4O4SCor e Forma:SolidPeso molecular:394.4Fipravirimat
CAS:Fipravirimat is a potent inhibitor of HIV-1 with potential applications in HIV and AIDS research.Fórmula:C43H67FN2O4SCor e Forma:SolidPeso molecular:727.07Antifungal agent 100
CAS:<p>Antifungal agent 100 (compound 3i) demonstrates notable antifungal activity, exhibiting an EC 50 of 0.33 mg/L against S. sclerotiorum. It also possesses an IC 50 value of 0.63 mg/mL targeting the Succinate dehydrogenase (SDH) of the same organism [1].</p>Fórmula:C23H21N3O4SCor e Forma:SolidPeso molecular:435.5SARS-CoV-2-IN-82
CAS:SARS-CoV-2-IN-82 (compound A) acts as an inhibitor of the Programmed-1 ribosomal frameshift (-1 PRF) in SARS-CoV-2 [1].Fórmula:C18H18N2Cor e Forma:SolidPeso molecular:262.35Metallo-β-lactamase-IN-13
CAS:Metallo-β-lactamase-IN-13 (Compound 13i) serves as a pan Metallo-β-Lactamase inhibitor with extended activity against Gram-negative (GN) bacteria expressing metallo-β-lactamases. It exhibits antibacterial properties effective against P. aeruginosa [1].Fórmula:C15H10F3N7O2S2Cor e Forma:SolidPeso molecular:441.41Antibiofilm agent-14
CAS:<p>Antibiofilm agent-14 (compound 11) functions as an antibiofilm agent. It exhibits antifungal activity against C.albicans SC5314, with a minimum inhibitory concentration (MIC) of 50 μM.</p>Fórmula:C26H30ClN3OCor e Forma:SolidPeso molecular:435.989Antibacterial agent 278
CAS:Antibacterialagent 278 (compound B1) is an antimicrobial agent that exhibits potent inhibitory activity against Gram-positive bacteria.Fórmula:C24H17ClF2N4O3Cor e Forma:SolidPeso molecular:482.87MBL-IN-5
CAS:MBL-IN-5 is an inhibitor of metallo-β-lactamase (MBL). It effectively suppresses three clinically significant B1 subfamily MBLs: NDM-1, VIM-1, and IMP-1 with IC50 values of 0.05 nM, 14 nM, and 21 nM respectively. MBL-IN-5 notably enhances the efficacy of carbapenem antibiotics against MBL-producing clinical strains and, when combined with IPM antibiotics, significantly reduces bacterial load in a thigh infection model.Fórmula:C20H16ClNO3Cor e Forma:SolidPeso molecular:353.80SARS-CoV-2-IN-80
CAS:SARS-CoV-2-IN-80 (compound 13), identified as a potent inhibitor of SARS-CoV-2 3CLpro, exhibits an IC50 value of 0.964 µM [1].Fórmula:C16H10O2SCor e Forma:SolidPeso molecular:266.31DNDI-8219
CAS:DNDI-8219 is an antitubercular agent. It has potent antileishmanial effects.Fórmula:C13H10F3N3O5Cor e Forma:SolidPeso molecular:345.23
