Microbiologia/Virologia
Os inibidores de microbiologia e virologia são compostos que têm como alvo microrganismos, incluindo bactérias, vírus e fungos, interrompendo seu crescimento, replicação ou sobrevivência. Esses inibidores são essenciais para estudar a patogênese microbiana, entender os mecanismos de resistência e desenvolver novas terapias antimicrobianas e antivirais. Os inibidores nessa categoria são usados para combater doenças infecciosas, explorar a ecologia microbiana e investigar as interações hospedeiro-patógeno. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para microbiologia e virologia para apoiar sua pesquisa em doenças infecciosas, microbiologia e virologia.
Subcategorias de "Microbiologia/Virologia"
- Antibacteriano(2.949 produtos)
- Antibiótico(919 produtos)
- Antifecção(23 produtos)
- DHFR(32 produtos)
- Síntese de DNA/RNA(707 produtos)
- HBV(176 produtos)
- HIV Protease(447 produtos)
- HSV(91 produtos)
- Integrase(2 produtos)
- Ribossomo(13 produtos)
Exibir 2 mais subcategorias
Foram encontrados 5832 produtos de "Microbiologia/Virologia"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Gallinamide A TFA
CAS:<p>Gallinamide A TFA is a peptide that exhibits linear deposition and serves as a potent inhibitor of cathepsin L (CatL) with an IC50 of 17.6 pM. It inhibits SARS-CoV-2 infection by targeting CatL (EC50: 28 nM) and also inhibits Plasmodium falciparum with an IC50 of 50 nM [1] [2].</p>Fórmula:C33H53F3N4O9Cor e Forma:SolidPeso molecular:706.79Corallopyronin A
CAS:<p>Corallopyronin A is an antibiotic that can be isolated from *Corallococcus coralloides* [1].</p>Fórmula:C30H41NO7Cor e Forma:SolidPeso molecular:527.65Farobin A
CAS:<p>Farobin A, a natural compound, exhibits antibacterial, antioxidant, and anti-inflammatory properties. It is effective against Streptococcus mutans ATCC 25175 and Streptococcus sobrinus ATCC 33478. Additionally, Farobin A demonstrates anti-inflammatory activity by targeting cytokine IL-6 and TNF-α [1].</p>Fórmula:C27H30O14Cor e Forma:SolidPeso molecular:578.52Pyrrocidine A
CAS:<p>Pyrrocidine A, an antibiotic known for its antibacterial properties, can be isolated from LL-Cyan426.</p>Fórmula:C31H37NO4Cor e Forma:SolidPeso molecular:487.63Tetrahydrobostrycin
CAS:<p>Tetrahydrobostrycin is a secondary metabolite produced by Aspergillus sp., demonstrating mild inhibitory effects against Staphylococcus aureus and Escherichia coli, with inhibition zones measuring 15 mm and 9.2 mm respectively (100 mg/disc).</p>Fórmula:C16H20O8Cor e Forma:SolidPeso molecular:340.33MMV1634566
<p>MMV1634566 is an effective antimalarial agent that can inhibit Plasmodium falciparum and exhibits cytotoxicity.</p>Cor e Forma:Odour SolidV-C6-Bg-PhCl TFA
<p>V–C6–Bg-PhCl TFA (compound 5e) is a biguanide-vancomycin conjugate with broad-spectrum antibacterial activity. It effectively eradicates biofilm-forming Gram-negative and Gram-positive bacteria.</p>Cor e Forma:Odour SolidDitercalinium chloride
CAS:<p>Ditercalinium chloride, an anticancer agent, inhibits human DNA polymerase gamma activity and can deplete mitochondrial DNA in both mouse and human cells. Additionally, Ditercalinium chloride is a potential ligand against the COMMD10-AP3S1 fusion protein [1] [2].</p>Fórmula:C46H50Cl2N6O2Cor e Forma:SolidPeso molecular:789.83POLRMT-IN-1
<p>POLRMT-IN-1 (compound S7) is an inhibitor of POLRMT, specifically utilized in cancer-related research.</p>Cor e Forma:Odour Solid3-Deoxyaphidicolin
CAS:<p>3-Deoxyaphidicolin is a phytotoxin that inhibits root growth in lettuce seedlings. Additionally, 3-Deoxyaphidicolin exhibits inhibitory activity against the protozoan parasites Leishmania major and Leishmania braziliensis.</p>Fórmula:C20H34O3Cor e Forma:SolidPeso molecular:322.48HYNIC-UBI29-41
CAS:<p>HYNIC-UBI29-41 is composed of the bifunctional chelator HYNIC and the antimicrobial peptide UBI 29-41. It retains the antimicrobial properties of UBI 29-41, showing strong affinity for both Gram-positive and Gram-negative bacteria. When labeled with the radioactive element Technetium (99mTc), HYNIC-UBI29-41 can be used as an imaging agent for detecting bacterial infections in mouse models.</p>Fórmula:C74H126N34O19SCor e Forma:SolidPeso molecular:1828.07SDH-IN-19
<p>SDH-IN-19 (compound A13) is a fungicide effective against Rhizoctonia solani, with an EC50 value of 0.83 μg/mL. It is utilized in agricultural research for fungal resistance in crops.</p>Cor e Forma:Odour SolidBMAP 28 (bovine)
CAS:<p>BMAP 28, bovine, is an antimicrobial peptide. It demonstrates antibacterial activity against both Gram-positive and Gram-negative bacteria by increasing cell membrane permeability and causing leakage of cell contents. Furthermore, BMAP 28, bovine, exhibits cytotoxic effects on cancer cells and activated human lymphocytes. It induces apoptosis through mitochondrial membrane potential depolarization.</p>Fórmula:C147H252N44O31Cor e Forma:SolidPeso molecular:3131.85SARS-CoV-2 Mpro-IN-43
<p>SARS-CoV-2 Mpro-IN-43 (Compound 1) is an inhibitor of the coronavirus main protease (Mpro) with an IC50 of 72 μM. It exerts its antiviral effects by interacting non-covalently with the key residues at the Mpro active site. This compound exhibits moderate to low cytotoxicity with CC50 values of 13.24, 41.02, and 42.26 µM in HaCaT, HEK293T, and HepG2 cells, respectively. SARS-CoV-2 Mpro-IN-43 is applicable for SARS-CoV-2 research.</p>Fórmula:C32H41F3N2O4S2Cor e Forma:SolidPeso molecular:638.24598LMW peptide
CAS:<p>LMW peptide, an antimicrobial peptide, exhibits activity against both Gram-positive and Gram-negative bacteria, including B.</p>Fórmula:C75H121N21O20S2Cor e Forma:SolidPeso molecular:1701.02SPR741 acetate
<p>SPR741 acetate, a polymyxin B derivative, enhances antibiotics against gram-negative bacteria by disrupting their outer membrane.</p>Fórmula:C46H77N13O15Pureza:98.57%Cor e Forma:SolidPeso molecular:1052.18Anhydrotetracycline hydrochloride
CAS:<p>Anhydrotetracycline (hydrochloride) is a potent competitive inhibitor of broad-spectrum tetracycline destructase enzymes.</p>Fórmula:C22H23ClN2O7Pureza:98.90%Cor e Forma:SolidPeso molecular:462.88Dusquetide aceate
<p>Dusquetide acetate: innate immune modulator with anti-inflammatory and antibacterial properties.</p>Fórmula:C27H51N9O7Pureza:97.33%Cor e Forma:SolidPeso molecular:613.751-Deoxymannojirimycin hydrochloride
CAS:<p>1-Deoxymannojirimycin hydrochloride is a selective α1,2-mannosidase inhibitor(IC50: 20 μM).</p>Fórmula:C6H14ClNO4Pureza:98%Cor e Forma:SolidPeso molecular:199.63Clindamycin palmitate hydrochloride
CAS:<p>Clindamycin palmitate hydrochloride (Clindamycin palmitate HCl) is the hydrochloride salt of clindamycin and palmitate, a lincosamide antibiotic.</p>Fórmula:C34H63ClN2O6S·HClPureza:98%Cor e Forma:SolidPeso molecular:699.85BRD1401
<p>BRD1401 is a small molecule that targets the outer membrane protein OprH. It disrupts the interaction between OprH and LPS and can increase membrane fluidity.</p>Fórmula:C17H17N5O3Peso molecular:339.13314Antibacterial agent 220
<p>Antibacterialagent 220 is a potent antibacterial compound that directly disrupts bacterial cell membranes. It is effective against both Gram-positive and Gram-negative bacteria, including resistant strains.</p>Fórmula:C37H54N8O8SPeso molecular:770.37853Protorubradirin
CAS:<p>Protorubradirin is an antibiotic that can be isolated from the non-pigmented Streptomyces achromogenes var. rubradiris alongside Rubradirin. It exhibits inhibitory activity against HIV reverse transcriptase. In vitro studies show that Protorubradirin also inhibits strains of Staphylococcus aureus and Streptococcus. In infected mice, subcutaneous administration of Protorubradirin demonstrates in vivo efficacy against antibiotic-resistant Staphylococcus aureus strains. However, oral administration may significantly reduce its activity compared to Rubradirin, possibly due to its C-nitroso sugar decomposing more rapidly in acidic gastric conditions.</p>Fórmula:C48H46N4O19Peso molecular:982.89DOTA-ubiquicidin (29-41)
<p>DOTA-ubiquicidin (29-41) is a derivative of an antimicrobial peptide fragment employed for synthesizing [68Ga]Ga-DOTA-Ubiquicidin29-41, which is subsequently utilized in PET/CT imaging of infection processes. Additionally, DOTA-ubiquicidin (29-41) is applicable in the synthesis and research of radiopharmaceuticals known as radionuclide conjugates (RDC).</p>Fórmula:C84H147N35O25SPeso molecular:2078.10281SARS-CoV-2 Mpro-IN-17
<p>SARS-CoV-2 Mpro-IN-17 (compound S5-28) is an orally active, non-covalent inhibitor of SARS-CoV-2 Mpro, with an EC50 value of 1.35 μM. It is applicable for research related to COVID-19.</p>Fórmula:C20H19BrClN3O2Peso molecular:447.03492TS-002266
CAS:<p>TS-0022666 is a selective TUT4/7 inhibitor, antiproliferative and anti-leukaemic in vivo and in vitro, cancers with FOCAD deficiency.</p>Fórmula:C31H32Cl2N6O5Pureza:98.18%Cor e Forma:SoildPeso molecular:639.5328-O-Imidazolyl-azepano-betulin
<p>SARS-CoV-2-IN-70 (compound 6) is an effective inhibitor of SARS-CoV-2, with an IC50 value of 3.2 μM.</p>Fórmula:C34H53N3O2Peso molecular:535.41378Mtb-IN-7
<p>Mtb-IN-7 (compound R7) is a MAO-A/MAO-B inhibitor with an IC50 greater than 40 μM. It exhibits antibacterial activity against Mycobacterium tuberculosis H37Rv, with a MIC of 2.01 μM.</p>Fórmula:C16H22FN3O5SPeso molecular:387.12642Gramicidin A TFA
<p>Gramicidin A (TFA) is a peptide component of Gramicidin, an antibiotic mixture originally isolated from B. brevis. It is a highly hydrophobic channel-forming ion carrier that creates monovalent cation-permeable channels in artificial membranes. Additionally, Gramicidin A (TFA) induces the degradation of hypoxia-inducible factor 1α (HIF-1α).</p>Fórmula:C99H140N20O17·xC2HF3O2Mpro ligand 1
<p>Mpro ligand 1 is the target protein ligand for PROTACSARS-CoV-2 Mpro degrader-3. It is the active form of Mpro ligand 2.</p>Fórmula:C22H32N3NaO9SPeso molecular:537.1757pppApA sodium
<p>pppApA sodium is a linear dinucleotide intermediate involved in the enzymatic production of bacterial signaling nucleotide c-diAMP. It is formed by the linkage of two ATP molecules.</p>Fórmula:C20H26N10Na2O19P4Peso molecular:880.01216OP-145
CAS:<p>OP-145 is a derivative of the antimicrobial peptide LL-37, known for its antibacterial properties against multiple MRSA strains. This compound is applicable in studies on chronic suppurative otitis media.</p>Fórmula:C142H246N46O31Peso molecular:3093.76Antibacterial agent 176
<p>Antibacterialagent 176 (Compound 6f) is a potent PqsR antagonist. It effectively inhibits Pseudomonas aeruginosa (P. aeruginosa CF), demonstrating significant suppression of pyocyanin and 2-alkyl-4(1H)-quinolone production.</p>Fórmula:C21H23ClN4O2Peso molecular:398.15095MPD2
<p>MPD2 is a PROTAC compound based on a Cereblon-binding ligand that degrades the main protease MPro of SARS-CoV-2. In 293T cells, it effectively reduces MPro protein levels with a DC50 of 296 nM and shows time-dependent activity. MPD2 exhibits strong antiviral properties against various SARS-CoV-2 strains and has increased potency against Nirmatrelvir-resistant variants. It holds potential for researching SARS-CoV-2 diseases.</p>Fórmula:C51H68N6O13Peso molecular:972.48444SARS-CoV-2-IN-83
<p>SARS-CoV-2-IN-83 (compound C6E) exhibits excellent activity against the SARS-CoV-2 spike protein.</p>Fórmula:C42H57N3O6Peso molecular:699.42474Mpro/Cathepsin L-IN-1
<p>Mpro/Cathepsin L-IN-1 (Compound 4d) is an inhibitor of SARS-CoV-2 Mpro and hCatL, with Ki values of 5.54 μM and 0.701 μM, respectively.</p>Fórmula:C24H32FN3O4Peso molecular:445.23768SARS-CoV-2 Mpro-IN-13
<p>SARS-CoV-2 Mpro-IN-13 (compound 20j) is a covalent inhibitor of the SARS-CoV-2 main protease (MPro) with an IC50 value of 19.0 nM and exhibits antiviral activity with an EC50 value of 138.1 nM.</p>Fórmula:C29H41F2N5O6SPeso molecular:625.27456Globomycin derivative G2A
<p>Globomycin derivative G2A (Compound G2A) is an inhibitor of lipoprotein signal peptidase II (LspA), with an IC50 of 604 nM. It exhibits inhibitory activity against E. coli, P. aeruginosa, and A. baumannii, displaying minimum inhibitory concentrations (MIC) ranging from 12.5 to 32 μg/mL.</p>Fórmula:C34H62N6O8Peso molecular:682.46291Antibacterial agent 185
<p>Antibacterialagent 185 (compound IP-01) is a potent antibacterial agent. It inhibits the polymerization and bundling of filamentous temperature-sensitive mutant Z (FtsZ) by enhancing GTP hydrolysis. Antibacterialagent 185 is effective against Streptococcus pneumoniae and displays a narrow spectrum of activity.</p>Fórmula:C18H17BrN2O3SPeso molecular:420.01433Herbimycin C
CAS:<p>Herbimycin C (AntibioticTAN 420D) is a bacterial metabolite originally isolated from S. hygroscopicus. It is cytotoxic to HeLa and Ehrlich cells, with IC50 values of 7.3 and 1.2 μg/mL, respectively.</p>Fórmula:C29H40N2O9Peso molecular:560.27338Antibacterial agent 226
<p>Antibacterialagent 226 (Compound 7f) is an antibacterial agent effective against Staphylococcus aureus strains, including methicillin-resistant S. aureus, with a MIC of 2 μg/mL. It exhibits cytotoxicity towards HEK293 cells with an IC50 of 1.9 μM.</p>Fórmula:C24H26F3N3O2Peso molecular:445.19771KN-17
<p>KN-17, a modified derivative based on the cecropin B structure, effectively disrupts bacterial growth and induces the migration of human bone marrow stromal cells (hBMSCs). This compound significantly stimulates angiogenesis both in vitro and in vivo.</p>Fórmula:C46H48N4O10Peso molecular:816.33704Dixanthogen
CAS:<p>Dixanthogen (Auligen) is an ectoparasiticide. Dixanthogen is a thiocarbonyl compound.</p>Fórmula:C6H10O2S4Pureza:95% - 98%Cor e Forma:SolidPeso molecular:242.4Plonmarlimab
CAS:<p>Plonmarlimab(TJ003234) is an anti-GM-CSF monoclonal antibody with potential antiviral activity for the study of immune disorders and novel coronavirus infection</p>Pureza:96.2% (SDS-PAGE); 95.4% (SEC-HPLC) - 96.2% (SDS-PAGE); 95.4% (SEC-HPLC)Cor e Forma:LiquidCarfecillin Sodium
CAS:<p>Carfecillin Sodium, a phenyl ester of Carbenicillin, becomes an active antibacterial in intestines, treating urinary infections.</p>Fórmula:C23H21N2NaO6SCor e Forma:SolidPeso molecular:476.48KRH-3955 Salt
CAS:<p>KRH-3955, a CXCR4 antagonist, is an orally bioavailable and extremely potent inhibitor of HIV-1 infection.</p>Fórmula:C40H63N7O18Pureza:98%Cor e Forma:SolidPeso molecular:929.96Enniatin F
CAS:<p>Enniatin F is a natural product that can be used as a reference standard. The CAS number of Enniatin F is 144446-20-8.</p>Fórmula:C36H63N3O9Cor e Forma:SolidPeso molecular:681.912Tetrahydroechinocandin B
CAS:<p>Tetrahydroechinocandin B is a cyclic hexapeptide containing a fatty acyl side chain. It also inhibits 1,3-beta-D-glucan synthesis.</p>Fórmula:C52H85N7O16Pureza:98%Cor e Forma:SolidPeso molecular:1064.27Ruboxyl
CAS:<p>Ruboxyl, a nitroxylated analog of daunorubicin, is an anthracycline antibiotic.</p>Fórmula:C36H46ClN4O10Pureza:98%Cor e Forma:SolidPeso molecular:730.23Astromicin Sulfate
CAS:<p>Astromicin Sulfate is an antibiotic with aminoglycoside structure. Astromicin Sulfate may produce depression of neuromuscular function.</p>Fórmula:C17H37N5O10SPureza:98%Cor e Forma:SolidPeso molecular:503.57
