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Microbiologia/Virologia

Microbiologia/Virologia

Os inibidores de microbiologia e virologia são compostos que têm como alvo microrganismos, incluindo bactérias, vírus e fungos, interrompendo seu crescimento, replicação ou sobrevivência. Esses inibidores são essenciais para estudar a patogênese microbiana, entender os mecanismos de resistência e desenvolver novas terapias antimicrobianas e antivirais. Os inibidores nessa categoria são usados para combater doenças infecciosas, explorar a ecologia microbiana e investigar as interações hospedeiro-patógeno. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para microbiologia e virologia para apoiar sua pesquisa em doenças infecciosas, microbiologia e virologia.

Subcategorias de "Microbiologia/Virologia"

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Foram encontrados 5842 produtos de "Microbiologia/Virologia"

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  • SARS-CoV-2-IN-30


    <p>SARS-CoV-2-IN-30: two-armed diphosphate benzene, antiviral IC50 0.6/6.9μM, disrupts membranes EC50 6.9μM.</p>
    Fórmula:C60H52O8P2
    Cor e Forma:Solid
    Peso molecular:963
  • Griseoluteic acid

    CAS:
    <p>Griseoluteic acid is a breakdown product of griseolutein A and B. Griseoluteic acid is a phenazine antibiotic and is originally isolated from S. griseoluteus.</p>
    Fórmula:C15H12N2O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:284.27
  • Antiangiogenic agent 8


    <p>Antiangiogenic agent 8 (Compound 3m) functions as both an antibacterial agent and an antiangiogenic compound. It shows minimum inhibitory concentrations (MIC) of 16, 8, 4, 16, and 8 μg/mL against E. coli, P. aeruginosa, B. subtilis, S. aureus, and C. glabrata, respectively, with minimum bactericidal concentrations (MBC) ranging from 32 to 64 μg/mL. This compound holds potential for applications in infection control and cardiovascular disease research.</p>
    Fórmula:C23H20ClNOS
    Cor e Forma:Solid
    Peso molecular:393.929
  • Antimalarial agent 42


    <p>Compound 42 (Compound 2), an antimalarial agent, effectively inhibits Plasmodium falciparum during the asexual blood stages (IC 50 &lt;0.5μM) and gametocytes (IC 50 is 0.14 μM).</p>
    Fórmula:C24H42N2
    Cor e Forma:Solid
    Peso molecular:358.6
  • HDAC-IN-85


    <p>HDAC-IN-85 (Compound 1) is an HDAC inhibitor capable of crossing the blood-brain barrier. It exhibits inhibitory effects on brain tumor cell lines and can induce acetylation, resulting in DNA double-strand breaks and promoting RAD51 ubiquitination, which disrupts the DNA repair process. HDAC-IN-85 is applicable in studies of glioblastoma.</p>
    Fórmula:C24H27FN4O5
    Cor e Forma:Solid
    Peso molecular:470.49
  • Ikarugamycin

    CAS:
    <p>Ikarugamycin, an antibiotic, is an inhibitor of clathrin-mediated endocytosis (CME).</p>
    Fórmula:C29H38N2O4
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:478.62
  • CCOE-5


    <p>CCOE-5 is a chalcone derivative with antimalarial activity, exhibiting an IC50 of 1.4 μg/mL against P. falciparum (3D7) and an IC50 of less than 5 μg/mL against P. falciparum (INDO). CCOE-5 shows potential for research in the anti-infective domain.</p>
    Fórmula:C34H31NO6
    Cor e Forma:Solid
    Peso molecular:549.61
  • SARS-CoV-2-IN-30 disodium


    <p>SARS-CoV-2-IN-30 disodium: antiviral diphosphate ester, IC50 0.6/6.9 μM against virus/spike transduction, disrupts liposomal membranes (EC50 6.9 μM).</p>
    Fórmula:C60H50Na2O8P2
    Cor e Forma:Solid
    Peso molecular:1006.96
  • HIV-1 inhibitor-81


    <p>HIV-1inhibitor-81 (Compound 14g) is an HIV-1 protease inhibitor with a Ki of 1.6 nM. This compound exhibits antiviral activity against HIV-1, with an EC50 value of 250 nM.</p>
    Fórmula:C32H44N2O8S
    Cor e Forma:Solid
    Peso molecular:616.77
  • Talaromycesone A

    CAS:
    <p>Talaromycesone A, from Talaromyces, fights S. epidermidis &amp; MRSA (IC50: 3.7 &amp; 5.48 μM), inhibits AChE (IC50: 7.49 μM).</p>
    Fórmula:C29H24O11
    Cor e Forma:Solid
    Peso molecular:548.5
  • 9-AMN


    <p>9-AMN is an inhibitor of the SARS-CoV-2 papain-like protease (SARS-CoV-2 PLpro), effectively reducing its deubiquitinating (DUB) activity and protease activity, with IC50 values of 4.55 µM and 4.15 µM, respectively. Additionally, 9-AMN suppresses the replication of the SARS-CoV variants Delta and Omicron in Calu-3 cells, with IC50 values of 1.04 µM and 2.35 µM, respectively.</p>
    Fórmula:C23H28N4O7
    Cor e Forma:Solid
    Peso molecular:472.49
  • Antiparasitic agent-24


    <p>Antiparasitic agent-24 (Compound 14a) is an antiparasitic compound with EC50 values of 0.005 μM for L. maj, 0.069 μM for L. don, 0.82 μM for T. brucei, and 4.1 μM for T. cruzi.</p>
    Fórmula:C23H22ClN7O2S
    Cor e Forma:Solid
    Peso molecular:495.98
  • Magnesium silicate

    CAS:
    <p>Mg silicate (MgO &amp; SiO2) used in antacids, deodorizing, decolorizing &amp; as antifungal.</p>
    Fórmula:MgO3Si
    Cor e Forma:Solid
    Peso molecular:100.39
  • Diaporthein B

    CAS:
    <p>Diaporthein B, a potent pimarane diterpene, inhibits M. tuberculosis (MIC: 3.1 μg/mL) and combats colon cancer cells (IC50: 1.5-3 μM/L).</p>
    Fórmula:C20H28O6
    Cor e Forma:Solid
    Peso molecular:364.43
  • 2,2-Dithiobis(Benzothiazole)

    CAS:
    <p>2,2-Dithiobis(Benzothiazole) inhibits MAPK8 and Pseudomonas aeruginosa and is commonly used as an accelerator in rubber and plastic synthesis.</p>
    Fórmula:C14H8N2S4
    Pureza:99.33%
    Cor e Forma:Solid
    Peso molecular:332.49
  • Nusinersen

    CAS:
    <p>Nusinersen (nusinersen) is a antisense oligonucleotide (ASO) for the treatment of pediatric and adult spinal muscular atrophy (SMA) and increases SMN proteinss.</p>
    Pureza:98.62%
    Cor e Forma:Solid
  • 5'-O-DMT-PAC-dA

    CAS:
    <p>5’-O-DMT-PAC-dA can be used in the synthesis of oligoribonucleotides[1].</p>
    Fórmula:C39H37N5O7
    Cor e Forma:Solid
    Peso molecular:687.74
  • Doramectin monosaccharide

    CAS:
    <p>Doramectin monosaccharide, an anthelmintic breakdown product, forms by acid hydrolysis of doramectin.</p>
    Fórmula:C43H62O11
    Cor e Forma:Solid
    Peso molecular:754.95
  • 3'-Deoxyuridine-5'-triphosphate trisodium


    <p>3'-dUTP trisodium, a nucleotide analogue, inhibits RNA polymerases I/II and UTP integration into RNA (Ki=2.0 μM).</p>
    Fórmula:C9H12N2Na3O14P3
    Cor e Forma:Soild
    Peso molecular:534.08
  • Spm viii

    CAS:
    <p>Spm viii is a derivative of the nucleoside antibiotic spicamycin that has antitumor activity.</p>
    Fórmula:C26H43N7O7
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:565.66
  • AB-343


    <p>AB-343 is a selective covalent inhibitor of SARS-CoV-2 Mpro with an IC50 of 8 nM and a Ki of 2.8 nM. It effectively inhibits the main protease of SARS-CoV-2 and several other coronaviruses and is active against some resistant variants. AB-343 can be utilized in research related to diseases associated with coronavirus infections.</p>
    Fórmula:C26H34F5N5O4
    Cor e Forma:Solid
    Peso molecular:575.57
  • Kievitone

    CAS:
    <p>Kievitone, an isoflavanone from Phaseolus vulgaris, has antifungal and antitumor properties.</p>
    Fórmula:C20H20O6
    Cor e Forma:Solid
    Peso molecular:356.37
  • Myristoyl glutamic acid sodium

    CAS:
    <p>Myristoyl glutamic acid sodium, a surfactant in amino acid cleansers, has mild antibacterial properties and cleanses the skin surface of excess oil and dirt.</p>
    Fórmula:C19H34NNaO5
    Pureza:99.91%
    Cor e Forma:Solid
    Peso molecular:379.47
  • HR-568


    <p>HR-568 displays broad-spectrum anti-enterovirus activity. It inhibits enterovirus strains EV-A71, E30, and CVA24 in MRC-5 cells, with EC50 values of 1.53 μM, 0.4 μM, and 1.22 μM, respectively. HR-568 targets the hydrophobic pocket on enterovirus capsid proteins, thereby hindering viral replication.</p>
    Fórmula:C24H18N4S
    Cor e Forma:Solid
    Peso molecular:394.49
  • Rugulosin

    CAS:
    <p>Rugulosin (RUG) is a bis-anthraquinoid pigment produced by fungi.</p>
    Fórmula:C30H22O10
    Cor e Forma:Solid
    Peso molecular:542.496
  • RdRP-IN-8


    <p>RdRP-IN-8 (compound 45) is an antiviral agent targeting influenza viruses. It inhibits the viral RNA-dependent RNA polymerase (RdRP) activity by disrupting the heterodimerization of the PA and PB1 subunits, with an IC50 value of 0.13 μM.</p>
    Fórmula:C23H21N3O6S
    Cor e Forma:Solid
    Peso molecular:467.49
  • Lankacidinol

    CAS:
    <p>Lankacidinol is an antibiotic that has antitumor and immunosuppressive activities.</p>
    Fórmula:C25H35NO7
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:461.55
  • Rolusafine

    CAS:
    <p>Rolusafine is an antifungal agent [1] .</p>
    Fórmula:C19H18N2O2
    Cor e Forma:Solid
    Peso molecular:306.36
  • Nitroxynil

    CAS:
    <p>Nitroxynil is an anthelmintic for adult/immature parasites, mainly used in Fasciola hepatica studies.</p>
    Fórmula:C7H3IN2O3
    Pureza:99.76%
    Cor e Forma:Solid
    Peso molecular:290.01
  • Loloatin B 10

    CAS:
    <p>Loloatin B 10 is a bioactive chemical.</p>
    Fórmula:C67H85N13O14
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1296.494
  • HIV-1 inhibitor-80


    <p>HIV-1inhibitor-80 (compound M44) is an HIV-1 inhibitor with an EC50 of 5-148 nM. It demonstrates excellent metabolic stability and low cytotoxicity in human plasma and liver microsomes.</p>
    Fórmula:C26H19N7O
    Cor e Forma:Solid
    Peso molecular:445.475
  • BNM-III-170

    CAS:
    <p>BNM-III-170 is able to inhibit HIV-1 viral entry into target cells.</p>
    Fórmula:C25H26ClF7N6O6
    Cor e Forma:Solid
    Peso molecular:674.96
  • Aurodox

    CAS:
    <p>Aurodox is a biochemical.</p>
    Fórmula:C44H62N2O12
    Cor e Forma:Solid
    Peso molecular:810.97
  • Chevalone B

    CAS:
    <p>Chevalone B, a meroterpenoid from E. chevalieri fungus, is cytotoxic with IC50s: KB cells 2.9 μg/ml, NCI-H187 9.8 μg/ml.</p>
    Fórmula:C28H40O5
    Cor e Forma:Solid
    Peso molecular:456.61
  • Malolactomycin C

    CAS:
    <p>Malolactomycin C (compound 1) is a macrocyclic lactone antifungal antibiotic isolated from the Streptomyces strain KP-3144. It effectively inhibits Botrytis cinerea (gray mold), thereby controlling various plant diseases, including gray mold infections.</p>
    Fórmula:C62H109N3O20
    Cor e Forma:Solid
    Peso molecular:1216.54
  • Antifungal agent 14

    CAS:
    <p>Antifungal 14: potent, broad-spectrum, low-minimum inhibitory concentration.</p>
    Fórmula:C18H19N7O3
    Cor e Forma:Solid
    Peso molecular:381.396
  • Aldgamycin E

    CAS:
    <p>Aldgamycin E is a neutral macrolide antibiotic agent from culture filtrates of Streptomyces lavendulae. Methanolysis produces methyl algarosides A &amp; B.</p>
    Fórmula:C37H58O15
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:742.856
  • Anti-MRSA agent 4


    <p>Compound 7a: potent, selective MRSA growth inhibitor; MIC ≤ 0.26 µM; non-cytotoxic, non-hemolytic.</p>
    Fórmula:C48H68F6N4O8
    Cor e Forma:Solid
    Peso molecular:943.07
  • CC 1014

    CAS:
    <p>CC 1014 is a polypeptide antibiotic isolated from Penicillium lilacinum that inhibits phosphorylation of ADP, Mg ATPase.</p>
    Fórmula:C62H111N11O13
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:1218.634
  • Junceellolide C

    CAS:
    <p>Junceellolide C: transcription inhibitor of cccDNA, curbs HBV DNA replication, EC50 of 5.19 &amp; 3.52μM in HepAD38 cells, potent anti-HBV.</p>
    Fórmula:C26H33ClO10
    Cor e Forma:Solid
    Peso molecular:540.99
  • Antileishmanial agent-30


    <p>Compound 17k, also known as Antileishmanial agent-30, effectively inhibits Leishmania with an IC50 of 0.2 μM for L. donovani. It exhibits a CC50 of &gt;100 μM and an SI of &gt;500, indicating significant selectivity and potency.</p>
    Fórmula:C23H21N5O2
    Cor e Forma:Solid
    Peso molecular:399.45
  • Tomopenem

    CAS:
    <p>Tomopenem is a penem antibiotic.</p>
    Fórmula:C23H35N7O6S
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:537.63
  • 5'-O-DMT-N4-Bz-2'-F-dC

    CAS:
    <p>5’-O-DMT-N4-Bz-2’-F-dC is a nucleoside with protective and modification effects.</p>
    Fórmula:C37H34FN3O7
    Cor e Forma:Solid
    Peso molecular:651.68
  • Antifungal agent 78


    <p>Antifungal agent 78 (compound 25am) exhibits potent activity, with an EC50 of 13.46 μM against Fusarium graminearum [1].</p>
    Fórmula:C18H12F2N2O2
    Cor e Forma:Solid
    Peso molecular:326.3
  • Altromycin E

    CAS:
    <p>Altromycin E is a new pluramycin-like antibiotic.</p>
    Fórmula:C46H57NO17
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:895.952
  • Longistyline A

    CAS:
    <p>Natural stilbene Longistyline A from Cajanus cajan leaves; antimicrobial against MRSA, MIC 1.56 μg/mL; neuroprotective.</p>
    Fórmula:C20H22O2
    Cor e Forma:Solid
    Peso molecular:294.39
  • Octaethylene glycol monododecyl ether

    CAS:
    <p>Octaethylene glycol monododecyl ether (C12E8) is a non-ionic surfactant and detergent, for assisting LOX activity assays and membrane protein extraction.</p>
    Fórmula:C28H58O9
    Pureza:97.30%
    Cor e Forma:Solid
    Peso molecular:538.75
  • 12R-LOX-IN-2

    CAS:
    <p>12R-LOX-IN-2 is a 12R-LOX inhibitor that inhibits the hyperproliferation of psoriatic cells and can be used in the study of psoriasis and other skin diseases.</p>
    Fórmula:C19H13NO
    Pureza:99.84%
    Cor e Forma:Solid
    Peso molecular:271.31
  • IDR-1018 acetate


    <p>IDR-1018 acetate is an innate defense regulator conjugate with a minimum inhibitory concentration (MIC) of 16 μg/mL against MRSA USA300 LAC, MRSA SAP 0017, and S. epidermidis ATCC14990. It serves a role in the synthesis of V-IDR1018 (vancomycin-innate defense regulator conjugate).</p>
    Fórmula:C71H126N26O12·xC2H4O2
    Cor e Forma:Solid
  • LAH4


    <p>Amphipathic peptide LAH4 forms a-helix, binds phospholipid membranes, and shows in vitro transfection on par with commercial reagents.</p>
    Fórmula:C132H228N38O27
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:2779.53