Microbiologia/Virologia
Os inibidores de microbiologia e virologia são compostos que têm como alvo microrganismos, incluindo bactérias, vírus e fungos, interrompendo seu crescimento, replicação ou sobrevivência. Esses inibidores são essenciais para estudar a patogênese microbiana, entender os mecanismos de resistência e desenvolver novas terapias antimicrobianas e antivirais. Os inibidores nessa categoria são usados para combater doenças infecciosas, explorar a ecologia microbiana e investigar as interações hospedeiro-patógeno. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para microbiologia e virologia para apoiar sua pesquisa em doenças infecciosas, microbiologia e virologia.
Subcategorias de "Microbiologia/Virologia"
- Antibacteriano(3.422 produtos)
- Antibiótico(945 produtos)
- Antifecção(27 produtos)
- DHFR(30 produtos)
- Síntese de DNA/RNA(808 produtos)
- HBV(186 produtos)
- HIV Protease(507 produtos)
- HSV(99 produtos)
- Integrase(2 produtos)
- Ribossomo(6 produtos)
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Foram encontrados 6441 produtos de "Microbiologia/Virologia"
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LL-BM123α
CAS:LL-BM123α is a basic antibiotic isolated from Nocardia species and exhibits moderate activity against Gram-negative bacteria.Fórmula:C30H53N9O17Peso molecular:811.79SARS-CoV-2 Mpro-IN-17
SARS-CoV-2 Mpro-IN-17 (compound S5-28) is an orally active, non-covalent inhibitor of SARS-CoV-2 Mpro, with an EC50 value of 1.35 μM. It is applicable for research related to COVID-19.Fórmula:C20H19BrClN3O2Peso molecular:447.0349228-O-Imidazolyl-azepano-betulin
SARS-CoV-2-IN-70 (compound 6) is an effective inhibitor of SARS-CoV-2, with an IC50 value of 3.2 μM.Fórmula:C34H53N3O2Peso molecular:535.41378Gramicidin A TFA
Gramicidin A (TFA) is a peptide component of Gramicidin, an antibiotic mixture originally isolated from B. brevis. It is a highly hydrophobic channel-forming ion carrier that creates monovalent cation-permeable channels in artificial membranes. Additionally, Gramicidin A (TFA) induces the degradation of hypoxia-inducible factor 1α (HIF-1α).Fórmula:C99H140N20O17·xC2HF3O2Mpro ligand 1
Mpro ligand 1 is the target protein ligand for PROTACSARS-CoV-2 Mpro degrader-3. It is the active form of Mpro ligand 2.Fórmula:C22H32N3NaO9SPeso molecular:537.1757Antifungal agent 96
Antifungalagent 96 (Compound WZ-2) is an antifungal agent with excellent blood-brain barrier permeability and brain penetration. It inhibits the growth of C. neoformans H99 and C. albicans 0304103, with MIC values of 0.016 and 32 μg/mL, respectively.Fórmula:C11H8N2O3SPeso molecular:248.02556pppApA sodium
pppApA sodium is a linear dinucleotide intermediate involved in the enzymatic production of bacterial signaling nucleotide c-diAMP. It is formed by the linkage of two ATP molecules.Fórmula:C20H26N10Na2O19P4Peso molecular:880.01216OP-145
CAS:OP-145 is a derivative of the antimicrobial peptide LL-37, known for its antibacterial properties against multiple MRSA strains. This compound is applicable in studies on chronic suppurative otitis media.
Fórmula:C142H246N46O31Peso molecular:3093.76Antibacterial agent 181
Antibacterialagent 181 (Compound 3f) is an effective cationic antibacterialagent (antibacterialagent) with low cytotoxicity. It exhibits a minimum inhibitory concentration (MIC) of 2 μg/mL against both Staphylococcus aureus and Escherichia coli.Fórmula:C33H41BrFN5O5Peso molecular:685.22751MPD2
MPD2 is a PROTAC compound based on a Cereblon-binding ligand that degrades the main protease MPro of SARS-CoV-2. In 293T cells, it effectively reduces MPro protein levels with a DC50 of 296 nM and shows time-dependent activity. MPD2 exhibits strong antiviral properties against various SARS-CoV-2 strains and has increased potency against Nirmatrelvir-resistant variants. It holds potential for researching SARS-CoV-2 diseases.Fórmula:C51H68N6O13Peso molecular:972.48444SARS-CoV-2-IN-83
SARS-CoV-2-IN-83 (compound C6E) exhibits excellent activity against the SARS-CoV-2 spike protein.Fórmula:C42H57N3O6Peso molecular:699.42474COE-PNH2
COE-PNH2 exhibits antibacterial activity against Mycobacterium abscessus (Mab) with an MIC90 of 26 μM. It disrupts bacterial cell wall and membrane integrity, possesses intracellular permeability, and lacks mitochondrial toxicity.Fórmula:C54H98Cl8N8O4Peso molecular:1202.52193KSK-104
KSK-104 exhibits potent antibacterial activity against Mycobacterium tuberculosis, with a minimum inhibitory concentration (MIC) of 0.78 μM. Its mechanism of action primarily involves the synthesis and salvage pathway of pyridoxal 5'-phosphate (PLP), as well as PLP-dependent enzymes and the oxidative stress network. KSK-104 is a promising candidate for developing novel anti-tuberculosis drugs targeted at drug-resistant strains of Mycobacterium tuberculosis.Fórmula:C22H20N2O4Peso molecular:376.14231PLpro-IN-2
PLpro-IN-2 (Compound 16) is an inhibitor of the SARS-CoV-2 papain-like protease (PLpro), with an IC50 value of 0.25 μM.Fórmula:C30H38N4O3SPeso molecular:534.26646Sortase A, S. aureus
CAS:Sortase A, S. aureus (SrtA) is found in many Gram-positive bacteria and facilitates the recruitment of cell surface proteins. It plays a crucial role in the attachment of various molecules on the cell surface.Antibacterial agent 182
Antibacterialagent 182 (compound 8c) is an antibacterial agent that exhibits activity against various Gram-positive bacteria, particularly displaying efficacy against vancomycin-resistant Enterococcus faecium (MIC ≤0.125 μg/mL). At sub-MIC levels, Antibacterialagent 182 can inhibit biofilm formation by Staphylococcus aureus and Pseudomonas aeruginosa.Fórmula:C14H5Br4F3N2OSPeso molecular:621.68082Antibacterial agent 185
Antibacterialagent 185 (compound IP-01) is a potent antibacterial agent. It inhibits the polymerization and bundling of filamentous temperature-sensitive mutant Z (FtsZ) by enhancing GTP hydrolysis. Antibacterialagent 185 is effective against Streptococcus pneumoniae and displays a narrow spectrum of activity.Fórmula:C18H17BrN2O3SPeso molecular:420.01433Herbimycin C
CAS:Herbimycin C (AntibioticTAN 420D) is a bacterial metabolite originally isolated from S. hygroscopicus. It is cytotoxic to HeLa and Ehrlich cells, with IC50 values of 7.3 and 1.2 μg/mL, respectively.Fórmula:C29H40N2O9Peso molecular:560.27338Antibacterial agent 226
Antibacterialagent 226 (Compound 7f) is an antibacterial agent effective against Staphylococcus aureus strains, including methicillin-resistant S. aureus, with a MIC of 2 μg/mL. It exhibits cytotoxicity towards HEK293 cells with an IC50 of 1.9 μM.Fórmula:C24H26F3N3O2Peso molecular:445.19771
