Microbiologia/Virologia
Os inibidores de microbiologia e virologia são compostos que têm como alvo microrganismos, incluindo bactérias, vírus e fungos, interrompendo seu crescimento, replicação ou sobrevivência. Esses inibidores são essenciais para estudar a patogênese microbiana, entender os mecanismos de resistência e desenvolver novas terapias antimicrobianas e antivirais. Os inibidores nessa categoria são usados para combater doenças infecciosas, explorar a ecologia microbiana e investigar as interações hospedeiro-patógeno. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para microbiologia e virologia para apoiar sua pesquisa em doenças infecciosas, microbiologia e virologia.
Subcategorias de "Microbiologia/Virologia"
- Antibacteriano(2.968 produtos)
- Antibiótico(922 produtos)
- Antifecção(23 produtos)
- DHFR(33 produtos)
- Síntese de DNA/RNA(711 produtos)
- HBV(177 produtos)
- HIV Protease(451 produtos)
- HSV(91 produtos)
- Integrase(2 produtos)
- Ribossomo(13 produtos)
Exibir 2 mais subcategorias
Foram encontrados 5863 produtos de "Microbiologia/Virologia"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
Antibacterial agent 63
CAS:<p>Aztreonam-siderophore conjugate 63 is an antibacterial agent that exhibits efficacy against Gram-negative bacteria through the linkage of aztreonam to a</p>Fórmula:C35H43N9O14S2Cor e Forma:SolidPeso molecular:877.9HIV-1 inhibitor-61
CAS:<p>HIV-1 Inhibitor-61 (2c) serves as a potent inhibitor of HIV-1 reverse transcriptase, exhibiting an EC50 value of 0.07 nM in NL4-3 wt MT-4 cells [1].</p>Fórmula:C24H24F2N2O2SCor e Forma:SolidPeso molecular:442.52And1 degrader 1
CAS:<p>And1 degrader 1 (Compound A15) is a degrader of acidic nucleoplasmic DNA-binding protein 1 (And1) that notably induces degradation of And1 in NSCLC cells. When combined with Olaparib (1 μM), And1 degrader 1 at a concentration of 5 μM effectively inhibits proliferation in A549 and H460 cells. This compound is applicable in cancer research studies.</p>Fórmula:C26H27Cl2N3OCor e Forma:SolidPeso molecular:468.42PKZ18
CAS:<p>PKZ18 is an antibiotic that inhibits bacterial growth with a MIC value of 32-64 μg/mL against most Gram-positive bacteria. It suppresses the in vivo transcription and translation of glycyl-tRNA synthetase mRNA. PKZ18 selectively targets stem I specifier loops in Gram-positive bacteria, directly reducing T-box transcription readthrough of associated genes. It prevents codon-anticodon pairing necessary for tRNA binding and is less likely to induce resistance.</p>Fórmula:C22H26N2O3SCor e Forma:SolidPeso molecular:398.518KPC-2-IN-2
<p>KPC-2-IN-2 (6c) inhibits KPC-2 enzyme in Klebsiella pneumoniae (Ki 0.038 μM) and boosts cefotaxime in E. coli KPC-2.</p>Fórmula:C12H10BN3O2SCor e Forma:SolidPeso molecular:271.1N6-Benzoyl-2'-deoxyadenosine monohydrate
CAS:<p>N6-Benzoyl-2'-deoxyadenosine monohydrate is a nucleoside analogue that helps diagnose bacterial infections by binding to double-stranded DNA and altering its structure, which can subsequently be detected using electrophoresis.</p>Fórmula:C17H19N5O5Cor e Forma:SolidPeso molecular:373.363G247
<p>G247 inhibits MsbA by keeping NBDs apart, blocking ATPase activity.</p>Fórmula:C24H19Cl2FO3Cor e Forma:SolidPeso molecular:445.31BM635 hydrochloride
<p>BM635 hydrochloride, an MmpL3 inhibitor, strongly blocks Divergent bacteriophage H37Rv (MIC50: 0.08 μM), with doubled in vivo potency.</p>Fórmula:C25H30ClFN2OCor e Forma:SolidPeso molecular:428.97Antibacterial agent 82
<p>Antibacterial agent 82 (compound 7p) is an antibacterial agent [1].</p>Fórmula:C22H18N2O2Cor e Forma:SolidPeso molecular:342.39Antibacterial agent 80
<p>Antibacterial agent 80 (compound 20) has antibacterial activity [1].</p>Fórmula:C14H21N3S2Cor e Forma:SolidPeso molecular:295.47SARS-CoV-2-IN-99
CAS:<p>SARS-CoV-2-IN-99 (compound 58) is an inhibitor of the main protease of SARS-CoV-2.</p>Fórmula:C20H16Br2NO4PCor e Forma:SolidPeso molecular:525.13CMX990
CAS:<p>CMX990, a SARS-CoV-2 3CL protease inhibitor, exhibits EC90 values of 9.6 nM in human bronchial epithelial cells (HBECs) and 101 nM in HeLa-ACE2 cells. It also demonstrates good ADME and pharmacokinetic properties [1].</p>Fórmula:C22H32F3N3O6Cor e Forma:SolidPeso molecular:491.50MB076
CAS:MB076 is an innovative heterocyclic triazole designed with enhanced plasma stability. It effectively inhibits seven distinct Class C Acinetobacter-derived cephalosporinases (ADCs) β-lactamase variants with K i values less than 1 μM. Additionally, MB076 demonstrates a synergistic effect when combined with various cephalosporins to restore pBCSK(−) susceptibility [1].Fórmula:C9H12BN7O5S2Peso molecular:373.18GT-055
<p>GT-055 (LCB18-055) is a novel inhibitor of broad-spectrum β-lactamase.</p>Fórmula:C13H20F3N5O8SCor e Forma:SolidPeso molecular:463.39RdRP-IN-4
<p>RdRP-IN-4, an oral arylbenzohydrazide, inhibits influenza A/B by targeting PB1 of RdRP, with EC50s of 53 nM (H1N1) and 20 nM (Flu B), and aids infected mice.</p>Fórmula:C17H17Br2N3O2Cor e Forma:SolidPeso molecular:455.14QPX7728 methoxy acetoxy methy ester
CAS:QPX7728 methoxy acetoxy methy ester is an inhibitor of boronic acid β-lactamase.Fórmula:C14H14BFO7Pureza:98%Cor e Forma:SolidPeso molecular:324.07BPR3P0128
CAS:<p>BPR3P0128, a non-nucleoside RNA-dependent RNA polymerase (RdRp) inhibitor, is effective orally and can inhibit various SARS-CoV-2 variants. It exhibits EC 50 values of 0.62 µM for SARS-CoV-2 and 0.14 µM for HCoV-229E, demonstrating potent anti-pancoronavirus activity at submicromolar concentrations. Additionally, BPR3P0128 displays synergistic antiviral effects when used in combination with Remdesivir [1].</p>Fórmula:C22H18BrN3O2Cor e Forma:SolidPeso molecular:436.30HldA/E-IN-1
CAS:<p>HldA/E-IN-1 (compound 8) is a dual inhibitor of HldA/E, exhibiting IC50 values of 17.2 μM and 67.8 μM, respectively. This compound is utilized in research on antibacterial infections.</p>Fórmula:C8H17FO13P2Cor e Forma:SolidPeso molecular:402.16InhA-IN-7
CAS:<p>InhA-IN-7 (Compound 11), a derivative of Triclocan, shows inhibitory activity against enoyl-acyl carrier protein reductase (InhA) with an IC50 of 96 nM. It effectively inhibits the proliferation of both wildtype and mutant strains of Mycobacterium tuberculosis, exhibiting minimum inhibitory concentrations (MICs) ranging from 19 to 75 μM [1].</p>Fórmula:C17H18Cl2O2Cor e Forma:SolidPeso molecular:325.23Antimalarial agent 3
<p>Antimalarial agent 3 has a potent IC50 of 0.035 μM against Plasmodium and high selectivity for mammalian cells.</p>Fórmula:C15H16BrN3O2Cor e Forma:SolidPeso molecular:350.21
