Microbiologia/Virologia
Os inibidores de microbiologia e virologia são compostos que têm como alvo microrganismos, incluindo bactérias, vírus e fungos, interrompendo seu crescimento, replicação ou sobrevivência. Esses inibidores são essenciais para estudar a patogênese microbiana, entender os mecanismos de resistência e desenvolver novas terapias antimicrobianas e antivirais. Os inibidores nessa categoria são usados para combater doenças infecciosas, explorar a ecologia microbiana e investigar as interações hospedeiro-patógeno. Na CymitQuimica, oferecemos uma ampla seleção de inibidores de alta qualidade para microbiologia e virologia para apoiar sua pesquisa em doenças infecciosas, microbiologia e virologia.
Subcategorias de "Microbiologia/Virologia"
- Antibacteriano(3.334 produtos)
- Antibiótico(937 produtos)
- Antifecção(26 produtos)
- DHFR(32 produtos)
- Síntese de DNA/RNA(796 produtos)
- HBV(189 produtos)
- HIV Protease(507 produtos)
- HSV(96 produtos)
- Integrase(2 produtos)
- Ribossomo(11 produtos)
Exibir 2 mais subcategorias
Foram encontrados 6383 produtos de "Microbiologia/Virologia"
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Antifungal agent 113
CAS:Antifungalagent 113 (compound 9a) serves as an effective antifungal and antibacterial agent. It exhibits strong inhibitory activity against both S. aureus and methicillin-resistant S. aureus.Fórmula:C23H20O5Cor e Forma:SolidPeso molecular:376.40HRSV/HMPV-IN-1
CAS:HRSV/HMPV-IN-1 (compound 3) is an inhibitor targeting HRSV/HMPV, exhibiting EC50 values of < 0.2 μM against human RSV-A and < 0.5 μM for human MPV A2 TN/94-49. This compound is utilized in the study of bronchiolitis and pneumonia.Fórmula:C34H31ClF2N4O5SCor e Forma:SolidPeso molecular:681.15MED6-189
CAS:MED6-189, an analog of kalihinol, disrupts the apicoplast functions and vesicular transport in the malignant malaria parasite (P. falciparum, IC50 < 50 nM). The compound specifically targets the apicoplast, which is a non-photosynthetic plastid essential for isoprenoid synthesis, found in most apicomplexan parasites.Fórmula:C17H26N2OCor e Forma:SolidPeso molecular:274.40NNRT-IN-5
CAS:NNRT-IN-5 (compound 10d) is an orally available non-nucleoside reverse transcriptase (Reverse Transcriptase) inhibitor.Fórmula:C27H22N8Cor e Forma:SolidPeso molecular:458.52Neuraminidase-IN-4
Neuraminidase-IN-4 inhibits neuraminidase (EC50: 1.59 μM) and has strong anti-H5N1 activity.Fórmula:C21H20N2O6SCor e Forma:SolidPeso molecular:428.461,5-Dideoxy-1,5-imino-D-mannitol
CAS:1,5-Dideoxy-1,5-imino-D-mannitol is an antibiotic with antibacterial properties.Fórmula:C6H13NO4Cor e Forma:SolidPeso molecular:163.172Tenellin
CAS:Tenellin is a fungal metabolite that inhibits Mg2+-, Ca2+-, and Na+/K+-ATPase activities in erythrocytes. Tenellin is cytotoxic to Sf9 and Sf21 insect cells.Fórmula:C21H23NO5Cor e Forma:SolidPeso molecular:369.41Antibacterial agent 281
CAS:Antibacterialagent 281 (Compound 95,186) effectively inhibits the growth of GAS by binding to the ligand-binding pocket of SPs0871, competing with the ligand. It exhibits concentration-dependent growth inhibition against Streptococcus pyogenes (S. pyogenes).Fórmula:C23H24N6OCor e Forma:SolidPeso molecular:400.48BAR-072
CAS:BAR-072 is a small molecule inhibitor targeting TraE with a KD value of 2.7 µM. It significantly suppresses the transfer of the antibiotic resistance-associated plasmid pKM101. BAR-072 holds promise as a candidate molecule for research in disease areas related to infection and resistance control, by inhibiting the spread of bacterial resistance genes.Fórmula:C18H13N3O6Cor e Forma:SolidPeso molecular:367.312β-Glucuronidase-IN-3
CAS:β-Glucuronidase-IN-3 (Compound 49) is a covalent allosteric inhibitor targeting β-glucuronidase. It exhibits potent inhibitory activity against Escherichia coli β-glucuronidase (EcGUS) with an IC50 of 12.9 nM. The compound exerts its inhibitory effect through reversible covalent modification of cysteine residues (Cys28, Cys443, and Cys197) on EcGUS. It is applicable in research on gut microbiota-related diseases, particularly in reducing the toxic side effects of Irinotecan and non-steroidal anti-inflammatory drugs (NSAIDs).Fórmula:C10H7N3OSeCor e Forma:SolidPeso molecular:264.14MMV03
CAS:MMV03 is an antimalarial compound effective against Plasmodium falciparum, with an EC50 of 0.6 μM.Fórmula:C19H14N4OSCor e Forma:SolidPeso molecular:346.406LY 215890
CAS:LY 215890 is a compound that exhibits potent Gram-negative and Gram-positive antibacterial activity.Fórmula:C13H12ClN5O5SPureza:98%Cor e Forma:SolidPeso molecular:385.78HCV NS5B polymerase-IN-2
CAS:HCVNS5B polymerase-IN-2 (Compound 298) is an inhibitor of the Ns5b polymerase. It holds potential for research into the treatment of hepatitis C virus (HCV) infections.Fórmula:C26H24N2O4Cor e Forma:SolidPeso molecular:428.48(R)-ZG197
(R)-ZG197: Activates Sa ClpP (EC50=1.5μM) & Hs ClpP (EC50=31.4μM); selective for Sa ClpP.Fórmula:C28H35F3N4O3Cor e Forma:SolidPeso molecular:532.6Cap-dependent endonuclease-IN-25
CAS:Cap-dependent endonuclease-IN-25 is a potent inhibitor of CEN, useful in studying Orthomyxoviridae viruses. (See WO2020075080A1, compound 4.)Fórmula:C25H25N3O3Cor e Forma:SolidPeso molecular:415.48Polθ-IN-8
CAS:Polθ-IN-8 (example 77) is a DNA polymerase θ (Polθ) inhibitor with an IC50 for Polθ ATPase activity of less than 100 nM. Polθ-IN-8 is useful for researching diseases related to Polθ activity, such as cancer.Fórmula:C22H22ClN7O3SCor e Forma:SolidPeso molecular:499.97Antimalarial agent 9
Antimalarial 9, a quinoline-imidazole derivative, effectively targets CQ-susceptible (IC50-0.14 μM) and MDR strains (IC50-0.41 μM) with low toxicity.Fórmula:C28H32BrN3O2Cor e Forma:SolidPeso molecular:522.48Anticaries agent-1
CAS:Anticaries agent-1 (Compound 21b) is utilized as an anticaries agent. It effectively inhibits biofilm formation with an IC50 of 77 μM and restricts the growth of S. mutans.Fórmula:C15H12O4Cor e Forma:SolidPeso molecular:256.253DC-159a
CAS:DC-159a, an 8-methoxy fluoroquinolone, possesses broad-spectrum antibacterial activity, with a particular efficacy against Gram-positive pathogens. The MIC90 values for DC-159a are 0.5 μg/mL against Streptococcus anginosus group, 4 μg/mL against Clostridium difficile, and 2 μg/mL against Bacteroides fragilis.Fórmula:C21H23F2N3O40·5H2OCor e Forma:SolidPeso molecular:428.4295Antitrypanosomal agent 6
Compound 18a: potent vs. T. brucei (IC50: 0.47 μM), >2x efficacy compared to Nifurtimox, good ADME, binds AT-rich DNA.Fórmula:C22H29Cl2N5OCor e Forma:SolidPeso molecular:450.4
