GluR
Inibidores do Receptor de Glutamato são compostos que bloqueiam a atividade dos receptores de glutamato, os principais receptores de neurotransmissores excitatórios no cérebro. Esses receptores desempenham um papel crucial na transmissão sináptica, plasticidade, aprendizado e memória. A desregulação da sinalização do glutamato está associada a vários distúrbios neurológicos, como epilepsia, AVC e doenças neurodegenerativas. Os inibidores dos receptores de glutamato são essenciais para investigar os mecanismos de excitotoxicidade e desenvolver estratégias neuroprotetoras. Na CymitQuimica, oferecemos uma gama de inibidores de receptores de glutamato para apoiar sua pesquisa em função sináptica, neuroproteção e distúrbios cognitivos.
Foram encontrados 255 produtos de "GluR"
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NBQX disodium
CAS:<p>NBQX Disodium (FG9202 disodium) is a highly selective, competitive AMPA receptor antagonist with neuroprotective and anticonvulsant activity.</p>Fórmula:C12H6N4Na2O6SPureza:97.6% - 98.22%Cor e Forma:SolidPeso molecular:380.2415Basimglurant
CAS:<p>Basimglurant (CTEP Derivative) is a potent, selective and orally available modulator of mGlu5 negative allosteric(Kd of 1.1 nM).</p>Fórmula:C18H13ClFN3Pureza:98.35%Cor e Forma:SolidPeso molecular:325.77AZD-8529 mesylate
CAS:AZD-8529 mesylate is a highly selective, and orally bioavailable positive allosteric modulator of mGluR2 (EC50: 285 nM).Fórmula:C25H28F3N5O6SPureza:99.19%Cor e Forma:SolidPeso molecular:583.58DHPG
CAS:<p>DHPG is a potent Group I mGluR agonist; doesn't affect Group II/III; linked to phospholipase D.</p>Fórmula:C8H9NO4Pureza:99.55%Cor e Forma:SolidPeso molecular:183.16Org-26576
CAS:<p>Org-26576 is a positive allosteric modulator of the AMPA receptor.</p>Fórmula:C11H12N2O2Pureza:99.67%Cor e Forma:SolidPeso molecular:204.23(R)-3,4-DCPG HCl
<p>(R)-3,4-DCPG HCl is a potent and selective mGlu8a receptor agonist that activates metabotropic glutamate receptors on primary afferent terminals in the neonatal</p>Fórmula:C10H10ClNO6Pureza:98.80% - 99.89%Cor e Forma:SoildPeso molecular:275.64LY339434 HCl
<p>LY339434 HCl is a low affinity GluR5 erythrocyte receptor agonist.LY339434 HCl causes rapid neuronal death primarily by affecting N-methyl-D-aspartate (NMDA)</p>Fórmula:C18H20ClNO4Pureza:97.96% - 99.68%Cor e Forma:SoildPeso molecular:349.81Decoglurant
CAS:<p>Decoglurant (RO4995819) is a negative allosteric modulator of mGluR2 and mGluR3 and it also is developed as an antidepressant.</p>Fórmula:C21H11F6N5Pureza:99.77%Cor e Forma:SolidPeso molecular:447.34(R)-ADX-47273
CAS:<p>(R)-ADX-47273 is a potent mGluR5 positive allosteric modulator(EC50 of 168 nM for potentiation ).</p>Fórmula:C20H17F2N3O2Pureza:99.87%Cor e Forma:SolidPeso molecular:369.36Piracetam
CAS:<p>Piracetam (UCB-6215), a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), is used in therapy of the extensive cognitive disorders.</p>Fórmula:C6H10N2O2Pureza:97.16%Cor e Forma:Crystals From Isopropanol SolidPeso molecular:142.16VU0650786
CAS:<p>VU0650786: selective mGlu3 NAM, CNS-penetrant, IC50 392 nM, shows antidepressant/anxiolytic effects in rodents.</p>Fórmula:C18H15ClFN5O2Pureza:99.09%Cor e Forma:SolidPeso molecular:387.8γ-DGG acetate(6729-55-1 free base)
CAS:<p>gamma-DGG acetate(6729-55-1 free base) (γ-D-Glutamylglycine) is a competitive blocker of AMPA receptor.</p>Fórmula:C9H16N2O7Pureza:99.81%Cor e Forma:SolidPeso molecular:264.23KM02894
CAS:<p>KM02894 inhibits glutamate release, potentially reducing cancer-induced bone pain in tumor studies.</p>Fórmula:C7H9N3OS2Pureza:99.98%Cor e Forma:SolidPeso molecular:215.3MPPG
CAS:<p>MPPG is a selective L-AP4-sensitive receptor antagonist (kD=9.2 μM).</p>Fórmula:C9H12NO5PCor e Forma:SolidPeso molecular:245.171(S)-3,4-DCPG HCl
<p>(S)-3,4-DCPG HCl is a selective mGluR8a agonist, impacting AV12-664 cells with an EC50 of 31 nM.</p>Fórmula:C10H10ClNO6Pureza:99.53% - 99.9%Cor e Forma:SoildPeso molecular:275.64(S)-3,4-DCPG
CAS:<p>(S)-3,4-DCPG ((S)-3,4-Dicarboxyphenylglycine) is a selective agonist of human metabotropic glutamate receptor 8a (mGluR8a).</p>Fórmula:C10H9NO6Pureza:98%Cor e Forma:SolidPeso molecular:239.18LY3020371
CAS:<p>LY3020371: potent, selective mGlu 2/3 receptor antagonist with Ki of 5.26 nM (hmGluR2) and 2.50 nM (hmGluR3); key in depression studies.</p>Fórmula:C15H15F2NO5SCor e Forma:SolidPeso molecular:359.34LY3027788
CAS:<p>LY3027788, potent oral prodrug of LY3020371, is a strong mGlu2/3 antagonist with notable antidepressant effects.</p>Fórmula:C25H31F2NO11SCor e Forma:SolidPeso molecular:591.58mGluR3 modulator-1
CAS:<p>1-ethyl-3-morpholin-4-yl tetrahydroisoquinoline: mGluR3 modulator, potential for Parkinson's.</p>Fórmula:C16H21N3OPureza:98.99%Cor e Forma:SolidPeso molecular:271.36LY2812223
CAS:<p>LY2812223: selective mGlu2 agonist; binds mGlu2/mGlu3 (Ki=144/156 nM).</p>Fórmula:C10H12N4O4SPureza:98%Cor e Forma:SolidPeso molecular:284.291H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)-
CAS:<p>1H-Pyrrolo[2,1-c][1,2,4]benzothiadiazine, 2,3,3a,4-tetrahydro-, 5,5-dioxide, (3aR)- is a low activity isomer of S 18986.</p>Fórmula:C10H12N2O2SPureza:99.96%Cor e Forma:SoildPeso molecular:224.28Pomaglumetad methionil anhydrous
CAS:<p>LY2140023, potential schizophrenia treatment, is an oral prodrug of LY404039, a selective mGlu2/3 agonist.</p>Fórmula:C12H18N2O7S2Pureza:98%Cor e Forma:SolidPeso molecular:366.41STX-107
CAS:<p>STX-107 is a potent and selective mGluR5 agonist for the study of Fragile X Syndrome.</p>Fórmula:C18H10FN3SPureza:99.17%Cor e Forma:SolidPeso molecular:319.36VU0483605
CAS:<p>VU0483605 is an effective and selective positive allosteric modulator of mGluR1 with EC50s of 390 and 356 nM for human and rat, respectively.</p>Fórmula:C20H10Cl3N3O3Pureza:99.61%Cor e Forma:SolidPeso molecular:446.67ML353
<p>ML353 activates TREK-1/2, binds mGlu5 SAM (Ki=18.2 nM), surpasses 5mpep, may address SAM activity/blocking.</p>Fórmula:C19H15FN2OPureza:99.98% - 99.98%Cor e Forma:SoildPeso molecular:306.33mGluR5 modulator 1
CAS:<p>mGluR5 modulator 1 is a positive modulator for mGluR5, used in schizophrenia and cognitive research.</p>Fórmula:C18H19ClFN3O2Cor e Forma:SolidPeso molecular:363.82KRP-199 sodium
<p>KRP-199 sodium sodium is highly potent and selective for AMPA-R in vitro and exhibits good neuroprotection in vivo.</p>Fórmula:C22H12F3N5Na2O7Pureza:97.27%Cor e Forma:SoildPeso molecular:561.33(S)-AMPA HCl
<p>(S)-AMPA HCl (L-AMPA HCl) is a selective AMPA receptor agonist with potential antidepressant activity. It can be used in research on Parkinson's disease.</p>Fórmula:C7H11ClN2O4Pureza:99.18%Cor e Forma:SolidPeso molecular:222.63MGS0274
CAS:<p>MGS0274, a lipophilic prodrug of mGlu2/3 agonist MGS0008, enhances oral bioavailability, potentially aiding schizophrenia research.</p>Fórmula:C21H32FNO7Cor e Forma:SolidPeso molecular:429.485L-AP3
CAS:<p>L-AP3 blocks mGluR, inhibits D/L-phosphoserine (IC50: 368/2087 μM).</p>Fórmula:C3H8NO5PCor e Forma:White Hygroscopic SolidPeso molecular:169.073MMPIP hydrochloride
CAS:<p>MMPIP hydrochloride is a selective antagonist of allosteric mGluR7.</p>Fórmula:C19H16ClN3O3Pureza:99.88%Cor e Forma:SolidPeso molecular:369.8(S,S)-BMS-984923
CAS:<p>(S,S)-BMS-984923 is a weak mGluR5 modulator with EC50 >1μM; less active than its potent counterpart.</p>Fórmula:C22H15ClN2O2Cor e Forma:SolidPeso molecular:374.82LY3027788 hydrochloride
CAS:<p>LY3027788 HCl, potent oral prodrug of LY3020371, targets mGlu2/3 with antidepressant effects.</p>Fórmula:C25H32ClF2NO11SCor e Forma:SolidPeso molecular:628.03(±)-LY367385
CAS:<p>(±)-LY367385 is the racemic form of LY367385, and LY367385 is a highly potent and selective mGluR1a antagonist.</p>Fórmula:C10H11NO4Cor e Forma:SolidPeso molecular:209.201JF-NP-26
<p>Releases pain-blocking raseglurant under 405 nm light. Inhibits Quisqualate. Analgesic in vivo. Quantum yield: 0.18.</p>Cor e Forma:SolidMGS0028
CAS:<p>MGS0028 is a selective agonist of metabotropic glutamate 2/3 receptor, it could reverse abnormal behaviors in mice induced by isolation rearing.</p>Fórmula:C8H8FNO5Cor e Forma:SolidPeso molecular:217.15GYKI-47261 dihydrochloride
CAS:<p>GYKI-47261 dihydrochloride is an AMPA receptor antagonist and CYP2E1 inducer, demonstrating broad-spectrum anticonvulsant and neuroprotective activities.</p>Fórmula:C18H17Cl3N4Pureza:98.32% - 99.14%Cor e Forma:SolidPeso molecular:395.71VU0364770 hydrochloride
CAS:VU0364770 hydrochloride: potent, selective mGlu4 PAM; EC50=290 nM (rat), 1.1 μM (human).Fórmula:C12H10Cl2N2OPureza:98%Cor e Forma:SolidPeso molecular:269.13NS-102
CAS:<p>NS-102 is a glutamate receptor and NMDA receptor antagonist that inhibits erythrocyanine (GluK2) and inhibits specific binding to the glur6 receptor.</p>Fórmula:C12H11N3O4Pureza:98.48% - 98.95%Cor e Forma:SolidPeso molecular:261.23JNJ-46778212
CAS:JNJ-46778212 (VU 0409551) is a selective and potent mGlu5 allosteric modulator (EC50: 260 nM) for the study of neurodissection.Fórmula:C20H17FN2O3Pureza:99.24%Cor e Forma:SolidPeso molecular:352.36LY341495
CAS:<p>LY341495 is a potent metabotropic glutamate receptor antagonist and can be used to study neurological disorders.</p>Fórmula:C20H19NO5Pureza:98.53% - 99.37%Cor e Forma:SolidPeso molecular:353.37VU0422288
CAS:<p>VU0422288 (ML396) is a type III mGlu receptor (mGlus) orthosteric modulator with inhibitory effects on mGluR4.VU0422288 can be used to study Rett syndrome.</p>Fórmula:C17H11Cl2N3O2Pureza:95.48%Cor e Forma:SolidPeso molecular:360.19GYKI 53655 hydrochloride
CAS:GYKI 53655 hydrochloride (LY300168 hydrochloride) is an antagonist of AMPA and is used in the study of neurological disorders.Fórmula:C19H21ClN4O3Pureza:98.02%Cor e Forma:SolidPeso molecular:388.85Ro 01-6128
CAS:<p>Positive allosteric modulator of mGlu1 receptors</p>Fórmula:C17H17NO3Pureza:98%Cor e Forma:SolidPeso molecular:283.32AMN082
CAS:<p>AMN082 is an mGluR7 agonist with antidepressant effects. Neuroprotective effect of AMN082 on neuronal apoptosis in rats with traumatic brain injury.</p>Fórmula:C28H30Cl2N2Pureza:97.13% - 98.63%Cor e Forma:SolidPeso molecular:465.46EGLU
CAS:<p>EGLU, an antidepressant and potent mGluR-2 antagonist, binds with a 66 μM Kd to (lS,3S)-ACPD sites.</p>Fórmula:C7H13NO4Pureza:99.98%Cor e Forma:SolidPeso molecular:175.18GYKI 52466 dihydrochloride
CAS:GYKI 52466 dihydrochloride is an AMPA/Kainate receptor antagonist with anticonvulsant activity and can be used to study neurological diseases.Fórmula:C17H17Cl2N3O2Pureza:99.38%Cor e Forma:SolidPeso molecular:366.24γ-DGG
CAS:<p>gamma-DGG is a competitive blocker of AMPA receptor.</p>Fórmula:C7H12N2O5Pureza:98%Cor e Forma:SolidPeso molecular:204.18LY487379
CAS:<p>LY487379: human mGluR2 PAM, boosts glutamate binding, aids cognitive flexibility, may treat schizophrenia. EC50: 1.7 μM (mGlu2), >10 μM (mGlu3).</p>Fórmula:C21H19F3N2O4SCor e Forma:SolidPeso molecular:452.45VU-1545
CAS:<p>VU-1545 is mGlu5 positive allosteric modulator.</p>Fórmula:C22H15FN4O3Pureza:98.8%Cor e Forma:SolidPeso molecular:402.38MPEP hydrochloride
CAS:<p>MPEP hydrochloride is an effective and highly specific non-competitive antagonist at the mGlu5 receptor subtype (IC50: 36 nM).</p>Fórmula:C14H12ClNPureza:99.87% - >99.99%Cor e Forma:SolidPeso molecular:229.7Lu AF21934
CAS:<p>Lu AF21934 is a brain-penetrant and selective mGlu4 receptor positive allosteric modulator (IC50: 500 nM, human).</p>Fórmula:C14H16Cl2N2O2Pureza:99.79%Cor e Forma:SolidPeso molecular:315.2AZD-8529
CAS:AZD-8529: selective, oral mGluR2 modulator, EC50 285 nM; inactive on mGluR1,3-8 at 20-25 M.Fórmula:C24H24F3N5O3Cor e Forma:SolidPeso molecular:487.47ADX-47273
CAS:<p>ADX-47273 (BA 94673139) is a positive and selective allosteric modulator for the metabotropic glutamate receptor subtype mGluR5(EC50=170 nM).</p>Fórmula:C20H17F2N3O2Pureza:97% - 99.18%Cor e Forma:SolidPeso molecular:369.36Chelidamic acid
CAS:<p>Chelidamic acid is a heterocyclic organic acid with a pyran skeleton. Chelidamic acid is inhibitors of glutamate decarboxylase, with a Ki of 33 μM.</p>Fórmula:C7H5NO5Pureza:98.11%Cor e Forma:Pale Yellow PowderPeso molecular:183.12ADX88178
CAS:<p>ADX88178 is a potent positive allosteric modulator for metabotropic glutamate receptor 4 (mGluR4) with EC50 of 4 nM for human mGluR4.</p>Fórmula:C12H12N6SPureza:99.55%Cor e Forma:SolidPeso molecular:272.33(S)-ATPO
CAS:<p>(S)-ATPO is Competitive antagonist at GluR1-4 (AMPA-preferring) receptors.</p>Fórmula:C11H19N2O7PPureza:98.37% - 99.41%Cor e Forma:SolidPeso molecular:322.25VU0364770
CAS:<p>VU0364770 (VU 0364770)(EC50=1.1 μM), a positive allosteric modulator(PAM) of mGlu4, shows insignificant activity at 68 other receptors, including other mGlu</p>Fórmula:C12H9ClN2OPureza:99.65% - >99.99%Cor e Forma:SolidPeso molecular:232.67VU0155094
CAS:<p>VU0155094 (ML 397) is a positive allosteric modulator with differential activity at the various group III mGluRs.</p>Fórmula:C24H24N2O4SPureza:97.21%Cor e Forma:SolidPeso molecular:436.52VU0155041
CAS:<p>VU0155041 is an effective and positive allosteric modulator/allosteric agonist at mGlu4 receptors (EC50: 798/693 nM, at human/rat).</p>Fórmula:C14H15Cl2NO3Pureza:99.52% - 99.56%Cor e Forma:SolidPeso molecular:316.18Farampator
CAS:<p>Farampator (CX-691) (CX-691;Org24448) is a positive modulator of AMPA receptor.</p>Fórmula:C12H13N3O2Pureza:99.84% - >99.99%Cor e Forma:SolidPeso molecular:231.25JNJ-40411813
CAS:<p>JNJ-40411813 (ADX-71149) (ADX-71149) is a new positive allosteric modulator of the metabotropic glutamate 2 receptor (mGlu2R, EC50: 147 nM).</p>Fórmula:C20H25ClN2OPureza:99.74%Cor e Forma:SolidPeso molecular:344.88XAP044
CAS:<p>XAP044 blocks mGlu7, inhibiting long-term potentiation in mouse brain with a half-maximal effect at 88nm.</p>Fórmula:C15H9IO4Pureza:97.41%Cor e Forma:SolidPeso molecular:380.13VU 0357121
CAS:<p>VU0357121, a positive allosteric modulator of mGlu5 (EC50: 33 nM), is inactive or very weakly antagonizing at other mGlu receptor subtypes.</p>Fórmula:C17H17F2NO2Pureza:99% - >99.99%Cor e Forma:SolidPeso molecular:305.32JNJ16259685
CAS:<p>JNJ16259685 (TN.T 16259685) is a selective mGluR1 antagonist, and inhibits the synaptic activation of mGluR1 in a concentration-dependent manner with IC50 of 19</p>Fórmula:C20H23NO3Pureza:98.31%Cor e Forma:SolidPeso molecular:325.4E4CPG
CAS:<p>E4CPG is a novel group I/II metabotropic glutamate receptor antagonist, more potent than (RS)-MCPG.</p>Fórmula:C11H13NO4Pureza:99.96%Cor e Forma:SolidPeso molecular:223.23MPEP
CAS:<p>MPEP is a selective mGlu5 receptor antagonist with IC50 of 36 nM, exhibits no appreciable activity at mGlu1b/2/3/4a/7b/8a/6 receptors.</p>Fórmula:C14H11NPureza:99.54%Cor e Forma:SolidPeso molecular:193.24Caroverine hydrochloride
CAS:Caroverine HCL: Blocks NMDA/AMPA receptors, antioxidant, calcium-blocker, and vasorelaxant, used for tinnitus research.Fórmula:C22H28ClN3O2Pureza:98.37% - 98.75%Cor e Forma:SolidPeso molecular:401.9NBQX
CAS:<p>NBQX (FG9202) is a potent, selective and competitive AMPA receptor antagonist. Neuroprotective and anticonvulsant; active in vivo.</p>Fórmula:C12H8N4O6SPureza:97.66% - 99.42%Cor e Forma:SolidPeso molecular:336.28CX614
CAS:<p>CX614 is a positive allosteric modulator of the AMPA receptor concerning AMPA.</p>Fórmula:C13H13NO4Pureza:97.37%Cor e Forma:SolidPeso molecular:247.25PHCCC
CAS:<p>PHCCC is a Group I mGluR antagonist and enhances mGluR4 function; also blocks mGluR2/8.</p>Fórmula:C17H14N2O3Pureza:>99.99%Cor e Forma:SolidPeso molecular:294.3MTEP
CAS:<p>MTEP: potent, selective mGluR5 antagonist; IC50=5 nM, Ki=16 nM; may have antidepressant/anxiolytic effects; useful in Parkinson's research.</p>Fórmula:C11H8N2SCor e Forma:SolidPeso molecular:200.26SIB-1757
CAS:<p>SIB-1757 (6-methyl-2-[(E)-phenyldiazenyl]pyridin-3) is a selective antagonist of mGlu5 metabotropic glutamate receptor subtype (hmGlu5, IC50 : 0.4 μM)</p>Fórmula:C12H11N3OPureza:97.37%Cor e Forma:SolidPeso molecular:213.24CTEP
CAS:<p>CTEP (RO 4956371) (RO4956371) is a novel, long-acting, orally bioavailable allosteric antagonist of mGlu5 receptor with IC50 of 2.2 nM, shows >1000-fold</p>Fórmula:C19H13ClF3N3OPureza:99.17%Cor e Forma:SolidPeso molecular:391.77Ro0711401
CAS:<p>Ro0711401 is an agonist of mGlu1 receptor.</p>Fórmula:C18H11F3N2O3Pureza:97.57%Cor e Forma:SolidPeso molecular:360.29YM90K
CAS:<p>YM90K (6-(1H-imidazol-1-yl)-7-nitro-2,3(1H,4H)-) hydrochloride is an antagonist of AMPA receptor.</p>Fórmula:C11H8ClN5O4Pureza:98.23%Cor e Forma:SolidPeso molecular:309.66Ro 67-7476
CAS:<p>Ro 67-7476 is a positive allosteric modulator of mGlu1 receptors.</p>Fórmula:C17H18FNO2SPureza:99.69%Cor e Forma:SolidPeso molecular:319.39(RS)-MCPG
CAS:<p>(RS)-MCPG ((±)-MCPG) is a non-selective group I/II metabotropic glutamate receptor antagonist.</p>Fórmula:C10H11NO4Pureza:99.96%Cor e Forma:SolidPeso molecular:209.23-MATIDA
CAS:<p>3-MATIDA is an effective mGluR-1 antagonist (IC50: 6.3 μM, rat mGluR-1a).</p>Fórmula:C8H9NO4SPureza:99.75% - 99.96%Cor e Forma:SolidPeso molecular:215.23CNQX
CAS:<p>CNQX (FG9065) is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.3 and 1.5 μM for AMPA and kainate receptors, respectively)</p>Fórmula:C9H4N4O4Pureza:99.70%Cor e Forma:Pale Yellow SolidPeso molecular:232.15trans-ACPD
CAS:trans-ACPD ((±)-trans-ACPD) is an equimolecular mixture of (1S, 3R)- and (1R, 3S)-ACPD.Fórmula:C7H11NO4Pureza:99.53%Cor e Forma:SolidPeso molecular:173.17TCN238
CAS:<p>TCN238 is an orally bioavailable positive allosteric modulator of the metabotropic glutamate receptor 4 (mGluR4with an EC50 of 1 μM).</p>Fórmula:C12H11N3Pureza:99.9% - 99.92%Cor e Forma:SolidPeso molecular:197.24VU0361737
CAS:VU0361737 (ML-128) is a mGlu4 PAM; EC50 is 240 nM (human) and 110 nM (rat), weak at mGlu5/8, inactive at mGlu1/2/3/6/7, CNS-penetrant.Fórmula:C13H11ClN2O2Pureza:99.60% - 99.85%Cor e Forma:SolidPeso molecular:262.69AMN082 free base
CAS:<p>AMN082 free base is a metabotropic glutamate receptor 7 allosteric agonist.</p>Fórmula:C28H28N2Pureza:97.75% - 97.79%Cor e Forma:SolidPeso molecular:392.54LY-404187
CAS:<p>LY404187 is a positive allosteric modulator of AMPA receptors</p>Fórmula:C19H22N2O2SPureza:99.34%Cor e Forma:SolidPeso molecular:342.46(RS)-3-Hydroxyphenylglycine
CAS:<p>(RS)-3-Hydroxyphenylglycine is a PI-linked metabotropic glutamate receptors agonist.</p>Fórmula:C8H9NO3Pureza:99.29%Cor e Forma:SolidPeso molecular:167.16(S)-3-Hydroxyphenylglycine
CAS:<p>(S)-3-Hydroxyphenylglycine is an agonist of group I metabotropic glutamate receptors (mGluRs).</p>Fórmula:C8H9NO3Pureza:99.65%Cor e Forma:SolidPeso molecular:167.161-BCP
CAS:<p>1-BCP (Piperonylic acid piperidide) is a centrally active drug that modulates AMPA receptor gated currents.</p>Fórmula:C13H15NO3Pureza:99.60%Cor e Forma:SolidPeso molecular:233.26FTIDC
CAS:FTIDC: potent, selective mGluR1 allosteric antagonist, weak on mGluR5. IC50: human 5.8 nM, mouse 3.1 nM. Noncompetitive.Fórmula:C18H23FN6OPureza:94.58%Cor e Forma:SolidPeso molecular:358.41MTEP hydrochloride
CAS:<p>MTEP hydrochloride (MTEP) is non-competitive mGlu5 antagonist (IC50 and Ki of 5 nM and 16 nM, respectively)</p>Fórmula:C11H9ClN2SPureza:99.58%Cor e Forma:SolidPeso molecular:236.72CFMTI
CAS:<p>CFMTI: potent mGluR1 allosteric antagonist, 2000x selectivity over mGluR5, IC50: 2.6 nM.</p>Fórmula:C19H16FN5OPureza:97.23%Cor e Forma:SolidPeso molecular:349.36DNQX
CAS:<p>DNQX (FG 9041) is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively)</p>Fórmula:C8H4N4O6Pureza:97.27% - 99.1%Cor e Forma:Off-White Powder With A Yellow TingePeso molecular:252.14JNJ-42153605
CAS:<p>JNJ-42153605 is a mGlu2 receptor positive allosteric modulator (EC50: 17 nM).</p>Fórmula:C22H23F3N4Pureza:97.25% - 98.57%Cor e Forma:SolidPeso molecular:400.44VU 0364439
CAS:<p>VU 0364439 is a mGlu4 positive allosteric modulator (C50: 19.8 nM).</p>Fórmula:C18H13Cl2N3O3SPureza:97.9%Cor e Forma:SolidPeso molecular:422.29CX516
CAS:<p>CX516 (Ampalex), an ampakine and nootropic, acts as an AMPA receptor positive allosteric modulator as a therapy for Alzheimer's disease, schizophrenia and MCI.</p>Fórmula:C14H15N3OPureza:99.04% - ≥95%Cor e Forma:Tan SolidPeso molecular:241.29FITM
CAS:<p>FITM is a potent negative allosteric modulator of mGlu1 receptor(Ki : 2.5 nM).</p>Fórmula:C18H18FN5OSPureza:97.25%Cor e Forma:SolidPeso molecular:371.43VU-29
CAS:<p>VU-29 is a positive allosteric mGlu5 receptor modulator with EC50=9 nM and Ki=244 nM for rmGluR5. It is selective for mGluR5 relative to other mGluR subtypes.</p>Fórmula:C22H16N4O3Pureza:99.63%Cor e Forma:SolidPeso molecular:384.39IDRA-21
CAS:IDRA-21 is a positive AMPA receptor modulator.Fórmula:C8H9ClN2O2SPureza:99.73%Cor e Forma:SolidPeso molecular:232.69HBT1
CAS:<p>HBT1 is an AMPA receptor potentiator that induces production of brain-derived neurotrophic factor (BDNF) and exhibits little agonistic effect in primary neurons</p>Fórmula:C16H17F3N4O2SPureza:99.52%Cor e Forma:SolidPeso molecular:386.39(S)-4CPG
CAS:<p>(S)-4CPG ((S)-4-Carboxyphenylglycine) is a competitive mGlu1 receptor antagonist that attenuates nociceptive hypersensitivity and nociceptive abnormalities associated with sciatic nerve constriction injuries in rats, and may be used in the study of neurological disorders.</p>Fórmula:C9H9NO4Pureza:99.96%Cor e Forma:SolidPeso molecular:195.17CX717
CAS:<p>CX 717 is a positive allosteric modulator of AMPA receptor which has an antidepressant-like effect.</p>Fórmula:C11H11N3O3Pureza:99.81%Cor e Forma:SoildPeso molecular:233.23VU0477886
CAS:<p>VU0477886: Potent mGlu4 PAM, effective in preclinical Parkinson's model HIC.</p>Fórmula:C20H13ClN4O3Pureza:98%Cor e Forma:SolidPeso molecular:392.80IEM 1754 2HBr
CAS:<p>IEM 1754 2HBr (IEM 1754 dihydrobromide) is a selective AMPA/kainate receptor blockers for GluR1 and GluR3 with IC50 of 6 μM.</p>Fórmula:C16H30N2·2HBrPureza:99.71% - 99.72%Cor e Forma:SolidPeso molecular:412.25VU6001966
CAS:<p>VU6001966: potent, selective mGlu2 inhibitor (IC50=78 nM), negative modulator, with good CNS penetration.</p>Fórmula:C17H15FN4O2Pureza:98%Cor e Forma:SolidPeso molecular:326.33BMT-145027
CAS:<p>BMT-145027 is a positive allosteric modulator of mGluR5 without inherent agonist activity (EC50 = 47 nM).</p>Fórmula:C23H14ClF3N4Pureza:99.62%Cor e Forma:SolidPeso molecular:438.83MFZ 10-7 hydrochloride
CAS:MFZ 10-7 hydrochloride is a highly potent and selective negative allosteric modulator of mGluR5 NAMFórmula:C15H10ClFN2Pureza:98%Cor e Forma:SolidPeso molecular:272.71NS 1209
CAS:<p>NS 1209 (SPD 502) is a AMPA receptor antagonist.</p>Fórmula:C24H27N4NaO7SPureza:98%Cor e Forma:SolidPeso molecular:538.55LY392098
CAS:<p>LY392098 (AMPA receptor modulator-3) is an allosteric modulator of AMPA receptor with EC50 of 4.4 μM and can be used in studies about mammalian nervous system.</p>Fórmula:C18H22FNO2SPureza:99.86%Cor e Forma:SolidPeso molecular:335.44VU 0469650
CAS:<p>VU 0469650 is a potent and selective negative allosteric modulator of mGluR1 (IC50 = 99 nM).</p>Fórmula:C22H28N4OPureza:98.03%Cor e Forma:SolidPeso molecular:364.48(1R,2S)-VU0155041
CAS:<p>(1R,2S)-VU0155041 is the cis regioisomer of VU0155041 and a partial agonist of mGluR4.</p>Fórmula:C14H15Cl2NO3Pureza:98.85%Cor e Forma:SolidPeso molecular:316.18Methoxy-PEPy
CAS:<p>Methoxy-PEPy is a potent and selective mGlu5 receptor inhibitor with an IC50 value of 1 nM.</p>Fórmula:C13H10N2OPureza:99.22%Cor e Forma:SolidPeso molecular:210.23LYPLAL1-IN-1
CAS:LYPLAL1-IN-1 is a selective covalent small-molecule inhibitor of Lysophospholipase-like 1 (IC50: 0.006 μM). LYPLAL1-IN-1 also enhances glucose production.Fórmula:C29H29N7O4Pureza:98%Cor e Forma:SolidPeso molecular:539.59(RS)-MCPG disodium salt
CAS:group I/group II metabotropic glutamate receptor antagonistFórmula:C10H11NNaO4Pureza:98%Cor e Forma:SolidPeso molecular:232.193,3'-Difluorobenzaldazine
CAS:<p>allosteric potentiator of mGlu5</p>Fórmula:C14H10F2N2Pureza:98%Cor e Forma:SolidPeso molecular:244.24VU0366248
CAS:<p>VU0366248 is a mGlu5 negative allosteric modulator.</p>Fórmula:C14H7ClF2N2OPureza:98%Cor e Forma:SolidPeso molecular:292.67L-AP4 monohydrate
CAS:<p>L-AP4 (L-APB) is a group III mGluR agonist with EC50s: 0.13μM (mGlu4), 0.29μM (mGlu8), 1.0μM (mGlu6), 249μM (mGlu7).</p>Fórmula:C4H12NO6PCor e Forma:SolidPeso molecular:201.115VU 0360223
CAS:<p>VU 0360223 is a negative allosteric modulator of mGlu5.</p>Fórmula:C15H9FN2SPureza:98%Cor e Forma:SolidPeso molecular:268.31ADX71743
CAS:<p>ADX71743 is a potent and selective negative allosteric modulator of metabotropic glutamate receptor 7.</p>Fórmula:C17H19NO2Cor e Forma:SolidPeso molecular:269.34mGlu4 receptor agonist 1
CAS:<p>Compound 62, an mGlu4 agonist, has a 308 nM EC50 with anxiolytic and antipsychotic effects.</p>Fórmula:C21H15ClN4O2Cor e Forma:SolidPeso molecular:390.82MAP4
CAS:<p>metabotropic glutamate receptor modulator</p>Fórmula:C5H12NO5PPureza:98%Cor e Forma:White SolidPeso molecular:197.13GRN-529
CAS:<p>GRN-529 is a selective negative allosteric modulator of the mGluR5 receptor.</p>Fórmula:C22H15F2N3O2Pureza:98%Cor e Forma:SolidPeso molecular:391.37DFMTI
CAS:<p>DFMTI can completely block the rmGlu1 L757V glutamate response.</p>Fórmula:C20H18F2N4OCor e Forma:SolidPeso molecular:368.38Z-Cyclopentyl-AP4
CAS:Group III mGlu receptor agonistFórmula:C6H12NO5PPureza:98%Cor e Forma:SolidPeso molecular:209.14LY456066
CAS:<p>LY456066 is a mGluR1 receptor-selective, negative allosteric modulator.</p>Fórmula:C19H23N3OSPureza:98%Cor e Forma:SolidPeso molecular:341.47JNJ-40068782
CAS:<p>JNJ-40068782 is a potent, selective and systemically active positive allosteric modulator of the mGlu2 receptor.</p>Fórmula:C21H23N3OPureza:98%Cor e Forma:SolidPeso molecular:333.43TASP0433864
CAS:<p>TASP0433864 enhances mGlu2 activity; EC50: 199 nM (human), 206 nM (rat); not an agonist.</p>Fórmula:C18H23N3O3Pureza:98%Cor e Forma:SolidPeso molecular:329.39(S)-3,5-DHPG
CAS:<p>group I mGlu receptor agonist</p>Fórmula:C8H9NO4Pureza:98%Cor e Forma:SolidPeso molecular:183.16HTL14242
CAS:<p>HTL14242 is a mGlu5 Negative Allosteric Modulator.</p>Fórmula:C16H8ClFN4Cor e Forma:SolidPeso molecular:310.71(RS)-PPG
CAS:<p>(RS)-PPG: Potent, selective III mGluRs agonist; EC50s: hmGluR4a 5.2μM, hmGluR6 4.7μM, hmGluR7b 185μM, hmGluR8a 0.2μM; neuroprotective, anticonvulsive.</p>Fórmula:C8H10NO5PPureza:98%Cor e Forma:SolidPeso molecular:231.14VU0431316
CAS:<p>VU0431316 is a negative mGlu5 allosteric modulator. It has activity in a mouse model of anxiety.</p>Fórmula:C14H9ClN6O2Pureza:98%Cor e Forma:SolidPeso molecular:328.71DCG-IV
CAS:DCG-IV: Class II mGluR agonist; anticonvulsant; neuroprotective; EC50: mGlu2R-0.35μM, mGlu3R-0.09μM; antagonizes Group I/III mGluRs.Fórmula:C7H9NO6Pureza:98%Cor e Forma:SolidPeso molecular:203.15VU0410425
CAS:VU0410425 is a metabotropic glutamate receptor subtype 1 negative allosteric modulator.Fórmula:C19H16ClN3O3Pureza:98%Cor e Forma:SolidPeso molecular:369.8AZ12216052
CAS:<p>AZ12216052 is a GRP8 antagonist with anxiolytic and anti-inflammatory activity and can be used to study obesity and metabolic disorders.</p>Fórmula:C19H22BrNOSPureza:99.29%Cor e Forma:SolidPeso molecular:392.35LY487379 hydrochloride
CAS:Positive allosteric modulator of mGlu2 receptorsFórmula:C21H20ClF3N2O4SPureza:98%Cor e Forma:SolidPeso molecular:488.91VU0361747
CAS:<p>VU0361747 is a positive allosteric modulators (PAM) of metabotropic glutamate receptor subtype 5 (mGlu5).</p>Fórmula:C19H17FN2O2Cor e Forma:SolidPeso molecular:324.35Auglurant
CAS:<p>Auglurant is a novel and selective mGlu5 antagonist (IC50: 11 nM (rat) and an IC50: 14 nM (human)). Auglurant has an acceptable CNS penetration.</p>Fórmula:C16H12FN5O2Cor e Forma:SolidPeso molecular:325.3Desmethyl-YM 298198
CAS:mGlu1-selective antagonistFórmula:C17H21ClN4OSPureza:98%Cor e Forma:SolidPeso molecular:364.89Foliglurax monohydrochloride
CAS:Foliglurax monohydrochloride, an antiparkinsonian, is a selective brain-penetrant mGluR4 PAM with an EC50 of 79 nM.Fórmula:C23H24ClN3O3SCor e Forma:SolidPeso molecular:457.97L-CCG-l
CAS:<p>group II metabotropic glutamate receptor agonist</p>Fórmula:C6H9NO4Pureza:98%Cor e Forma:SolidPeso molecular:159.14(1S,3R)-ACPD
CAS:<p>(1S,3R)-ACPD is a group I and II mGlu receptor agonist.</p>Fórmula:C7H11NO4Pureza:98%Cor e Forma:SolidPeso molecular:173.17VU0404251
CAS:<p>VU0404251 is a positive allosteric modulator of mGlu5.</p>Fórmula:C19H23FN2O2Cor e Forma:SolidPeso molecular:330.4Mavoglurant racemate
CAS:<p>Mavoglurant is a novel, non-competitive mGlu5 receptor antagonist. Mavoglurant (racemate) is the racemate of mavoglurant.</p>Fórmula:C19H23NO3Pureza:98%Cor e Forma:SolidPeso molecular:313.39ACPT-II
CAS:<p>metabotropic receptor antagonist</p>Fórmula:C8H11NO6Pureza:98%Cor e Forma:SolidPeso molecular:217.18DL-AP4 Sodium salt
CAS:Broad spectrum EAA ligandFórmula:C4H10NNaO5PPureza:98%Cor e Forma:SolidPeso molecular:206.09UPF-523
CAS:group I metabotropic glutamate receptors (mGlu1a) antagonistFórmula:C11H11NO4Pureza:98%Cor e Forma:White SolidPeso molecular:221.21JNJ-46356479
CAS:<p>JNJ-46356479: Selective, oral mGlu2 receptor PAM, EC50=78 nM, Emax=256%.</p>Fórmula:C22H22F5N5Cor e Forma:SolidPeso molecular:451.44ACPT-I
CAS:<p>Agonist for group III mGlu receptors</p>Fórmula:C8H11NO6Pureza:98%Cor e Forma:SolidPeso molecular:217.18VU0364289
CAS:<p>VU0364289 is a positive allosteric modulator of mGlu5.</p>Fórmula:C20H21N3O2Cor e Forma:SolidPeso molecular:335.4(S)-4C3HPG
CAS:<p>group I mGlu1a/1a receptor antagonist and mGluR2 agonist</p>Fórmula:C9H9NO5Pureza:98%Cor e Forma:SolidPeso molecular:211.17LSN2814617
CAS:<p>LSN2814617: oral, brain-penetrant mGlu5 PAM, EC50 = 52 nM (human), 42 nM (rat). Promotes wakefulness, useful in schizophrenia study.</p>Fórmula:C18H20FN5OPureza:98%Cor e Forma:SolidPeso molecular:341.38RO4988546
CAS:<p>RO4988546 is a potent negative allosteric modulator of mGlu₂/₃.</p>Fórmula:C21H10F6N4O3SPureza:98%Cor e Forma:SolidPeso molecular:512.38mGluR2 modulator 1
CAS:<p>Potent mGluR2 modulator 1 crosses blood-brain barrier, EC50: 0.03 μM, useful for psychiatric research.</p>Fórmula:C21H20F3N3O3Cor e Forma:SolidPeso molecular:419.4NPEC-caged-LY379268
CAS:<p>NPEC-caged-LY379268 is a type II mGluR agonist [1].</p>Fórmula:C16H16N2O9Cor e Forma:SolidPeso molecular:380.31A 841720
CAS:<p>Potent, selective mGlu1 antagonist A-841720; IC50: 10 nM; 34x selectivity vs mGlu5; analgesic potential.</p>Fórmula:C17H21N5OSCor e Forma:SolidPeso molecular:343.45RO5488608
CAS:<p>RO5488608 is a new type of high-efficiency mGlu2/3 NAM.</p>Fórmula:C23H17F3N2O4SCor e Forma:SolidPeso molecular:474.45Talaglumetad hydrochloride
CAS:<p>Talaglumetad hydrochloride, a prodrug of Eglumegad, targets mGluR2/3 to treat psychiatric disorders.</p>Fórmula:C11H17ClN2O5Cor e Forma:SolidPeso molecular:292.72mGluR2 modulator 2
CAS:<p>mGluR2 modulator 2: potent, selective, oral, EC50 = 0.13 μM, for antipsychotic research.</p>Fórmula:C20H22FN3Cor e Forma:SolidPeso molecular:323.41VU0418506
CAS:<p>VU0418506 is a positive allosteric modulator (PAM) of the metabotropic glutamate receptor 4 (mGlu4).</p>Fórmula:C12H8ClFN4Pureza:98%Cor e Forma:SolidPeso molecular:262.67ACDPP hydrochloride
CAS:<p>mGlu5 receptor antagonist</p>Fórmula:C12H13ClN6OPureza:98%Cor e Forma:SolidPeso molecular:292.72Ro 64-5229
CAS:<p>mGlu2 antagonist</p>Fórmula:C17H19Cl2N3OPureza:98%Cor e Forma:SolidPeso molecular:352.26VU6010572
CAS:<p>VU6010572: potent, selective mGlu3 modulator, IC50 245 nM, high CNS penetration.</p>Fórmula:C20H18FNO3Cor e Forma:SolidPeso molecular:339.36VU0463841
CAS:<p>VU0463841 is a mGlu5 negative allosteric modulators.</p>Fórmula:C13H8ClFN4OCor e Forma:SolidPeso molecular:290.68VU 0360172 hydrochloride
CAS:<p>positive allosteric modulator of mGlu5 receptors</p>Fórmula:C18H16ClFN2OPureza:98%Cor e Forma:SolidPeso molecular:330.78mGluR2 modulator 4
CAS:<p>Compound 47 is a potent mGluR2 enhancer with an EC50 of 0.8 μM, potentially useful for antipsychotic research.</p>Fórmula:C18H18BrN3Cor e Forma:SolidPeso molecular:356.26VU0400195
CAS:<p>VU0400195 is a oral effective, positive allosteric modulator of the metabotropic glutamate receptor 4 (mGlu(4)).</p>Fórmula:C21H16ClN3O3Pureza:98%Cor e Forma:SolidPeso molecular:393.82(RS)-4-Carboxy-3-hydroxyphenylglycine
CAS:<p>broad spectrum EAA agonist/antagonist</p>Fórmula:C9H9NO5Pureza:98%Cor e Forma:SolidPeso molecular:211.17Ro4491533
CAS:<p>Ro4491533 is a potent and selective negative allosteric modulator for group II of the metabotropic glutamate receptors (mGluR2/3).</p>Fórmula:C24H20F3N3OCor e Forma:SolidPeso molecular:423.43MMPIP
CAS:<p>allosteric mGlu7-selective receptor antagonist</p>Fórmula:C19H15N3O3Pureza:98%Cor e Forma:SolidPeso molecular:333.34LSP4-2022
CAS:<p>LSP4-2022, a mGlu4 selective agonist, increases behavioral despair in mouse models of antidepressant action.</p>Fórmula:C13H18NO8PPureza:100%Cor e Forma:SolidPeso molecular:347.26VU0424465
CAS:<p>VU0424465 is a mGlu5-selective allosteric agonist.</p>Fórmula:C19H19FN2O2Cor e Forma:SolidPeso molecular:326.36VU0409106
CAS:<p>VU0409106 is a potent, mGlu5-selective inhibitor.</p>Fórmula:C15H11FN4O2SPureza:98%Cor e Forma:SolidPeso molecular:330.34Remeglurant
CAS:<p>Remeglurant is used as a selective antagonist of the mGlu5 receptor.</p>Fórmula:C17H15BrN4OCor e Forma:SolidPeso molecular:371.23IEM 1925 dihydrobromide
CAS:<p>AMPA receptor antagonist</p>Fórmula:C17H30Br2N2Pureza:98%Cor e Forma:SolidPeso molecular:422.24PHCCC(4Me)
CAS:<p>THCCC, a PHCCC analog, is a dual metabotropic glutamate receptor 2/3 negative/positive allosteric modulator.</p>Fórmula:C18H16N2O3Cor e Forma:SolidPeso molecular:308.33MSOP
CAS:MSOP is a selective antagonist of group III metabotropic glutamate receptor (KD of 51 μM for the L-AP4-sensitive presynaptic mGluR).Fórmula:C4H10NO6PPureza:98%Cor e Forma:SolidPeso molecular:199.1CFMMC
CAS:<p>CFMMC is an allosteric mGluR1 antagonist agent.</p>Fórmula:C22H28FNO4Cor e Forma:SolidPeso molecular:389.46YM 230888
CAS:<p>Selective mGlu1 antagonist</p>Fórmula:C19H28N4OSPureza:98%Cor e Forma:SolidPeso molecular:360.52LY2607540
CAS:<p>LY2607540 is a metabotropic glutamate 2 potentiator with potential anxiolytic/antidepressant properties (EC(50) = 23 and 13 nM, respectively).</p>Fórmula:C24H24F3N3O4Pureza:98%Cor e Forma:SolidPeso molecular:475.46(S)-HexylHIBO
CAS:<p>Group I mGlu receptor antagonist</p>Fórmula:C12H20N2O4Pureza:98%Cor e Forma:SolidPeso molecular:256.3LSP1-2111
CAS:<p>LSP1-2111 is a mGlu4 receptor subtype agonist.</p>Fórmula:C12H17N2O9PCor e Forma:SolidPeso molecular:364.25Lu-AF11205
CAS:<p>Lu-AF11205 is a potent positive allosteric modulator (PAM) of mGlu5 receptor.</p>Fórmula:C17H16N2OSPureza:98%Cor e Forma:SolidPeso molecular:296.39(RS)-4-Carboxyphenylglycine
CAS:<p>(RS)-4-Carboxyphenylglycine is a racemic mixture. (S)-4-Carboxyphenylglycine is a selective mGlu1α receptor antagonist.</p>Fórmula:C9H9NO4Pureza:99.04% - >99.99%Cor e Forma:SolidPeso molecular:195.17(R)-4-Carboxyphenylglycine
CAS:<p>(R)-4-Carboxyphenylglycine is a NMDA receptor antagonist.</p>Fórmula:C9H9NO4Pureza:98%Cor e Forma:SolidPeso molecular:195.17VU0652835
CAS:<p>VU0652835 is a negative allosteric modulator of metabotropic glutamate receptor subtype 5 (mGlu5) (IC50: 81 nM).</p>Fórmula:C16H19N3O3SPureza:98%Cor e Forma:SolidPeso molecular:333.41JNJ-55511118
CAS:<p>JNJ-55511118 is a TARP γ8 allosteric modulator with anticonvulsant activity, which can be used in research on chronic operant alcohol self-administration.</p>Fórmula:C14H8ClF3N2O2Cor e Forma:SolidPeso molecular:328.67DCB
CAS:<p>DCB is an mGluR5 allosteric ligand that blocks mGluR modulation, countering DMeOB and DFB effects.</p>Fórmula:C14H10Cl2N2Pureza:99.12% - 99.9%Cor e Forma:SolidPeso molecular:277.15ML337
CAS:ML337 is a negative allosteric modulator of mGlu3 with an IC50 of 593 nM.Fórmula:C21H20FNO3Pureza:99.83%Cor e Forma:SolidPeso molecular:353.39LY382884
CAS:<p>LY382884 is a selective and potent GluR5 kainate receptor antagonist with anxiolytic activity.LY382884 blocks blockade of mossy fibre LTP induction.</p>Fórmula:C18H23NO4Pureza:98.32% - 98.71%Cor e Forma:SolidPeso molecular:317.38TC-N 22A
CAS:<p>TC-N 22A is a strong, selective, oral active mGlu4 forward allosteric regulator (PAM) that can cross the blood-brain barrier.</p>Fórmula:C14H13N5SPureza:99.95%Cor e Forma:SolidPeso molecular:283.35CPPHA
CAS:<p>CPPHA, a positive allosteric modulator of glutamate receptors mGluR5 and mGluR1, is commonly used in development for central nervous system diseases.</p>Fórmula:C22H15ClN2O4Pureza:98.07%Cor e Forma:SolidPeso molecular:406.82ML289
CAS:<p>ML289 is a potent CNS-penetrant mGlu3 modulator with IC50 of 0.66 μM, >15-fold selectivity over mGlu2, and inactive against mGlu5.</p>Fórmula:C22H23NO3Pureza:99.54%Cor e Forma:SolidPeso molecular:349.42Foliglurax
CAS:<p>Foliglurax is a highly selective brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) (EC50: 79 nM).</p>Fórmula:C23H23N3O3SPureza:98%Cor e Forma:SolidPeso molecular:421.51VU6001376
CAS:<p>VU6001376 is an effective and selective positive allosteric modulator of the metabotropic glutamate receptor 4 (EC50: 50.1 nM).</p>Fórmula:C18H14F2N6OSPureza:98%Cor e Forma:SolidPeso molecular:400.41Ro 67-4853
CAS:<p>Ro 67-4853 is a positive allosteric modulator of mGluR1, selectively enhancing the response to the agonist (S)-3,5-dihydroxy-phenylglycine (DHPG).</p>Fórmula:C19H19NO4Pureza:98.57%Cor e Forma:SolidPeso molecular:325.36VU0155041 sodium
CAS:VU0155041 sodium is a positive allosteric modulator of mGluR4 that promotes extinction in male rats.Fórmula:C14H14Cl2NNaO3Pureza:98%Cor e Forma:SolidPeso molecular:338.16HexylHIBO
CAS:<p>HexylHIBO is a type I mGluR antagonist that inhibits mGlu1a and mGlu5a, with Kb values of 140 and 110 μM, respectively.HexylHIBO decreases sEPSC in rats.</p>Fórmula:C12H20N2O4Pureza:99.55%Cor e Forma:SolidPeso molecular:256.3(S)-MCPG
CAS:<p>(S)-MCPG is the active isomer of (RS)-MCPG, non-selective group I/group II metabotropic glutamate receptor antagonist.</p>Fórmula:C10H11NO4Pureza:98.72%Cor e Forma:SolidPeso molecular:209.20DMeOB
CAS:<p>DMeOB (3,3'-Dimethoxybenzaldazine) is a negative regulator with mGluR5 agonist activity and is used in the study of neurological disorders.</p>Fórmula:C16H16N2O2Pureza:98.34%Cor e Forma:SolidPeso molecular:268.31A-794282
CAS:<p>A-794282 is a selective antagonist of mGluR1.</p>Fórmula:C19H18N4OSPureza:99.87%Cor e Forma:SolidPeso molecular:350.44
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