GluR
Inibidores do Receptor de Glutamato são compostos que bloqueiam a atividade dos receptores de glutamato, os principais receptores de neurotransmissores excitatórios no cérebro. Esses receptores desempenham um papel crucial na transmissão sináptica, plasticidade, aprendizado e memória. A desregulação da sinalização do glutamato está associada a vários distúrbios neurológicos, como epilepsia, AVC e doenças neurodegenerativas. Os inibidores dos receptores de glutamato são essenciais para investigar os mecanismos de excitotoxicidade e desenvolver estratégias neuroprotetoras. Na CymitQuimica, oferecemos uma gama de inibidores de receptores de glutamato para apoiar sua pesquisa em função sináptica, neuroproteção e distúrbios cognitivos.
Foram encontrados 263 produtos para "GluR".
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DCB
CAS:DCB is an mGluR5 allosteric ligand that blocks mGluR modulation, countering DMeOB and DFB effects.Fórmula:C14H10Cl2N2Pureza:99.12% - 99.9%Cor e Forma:Yellow SolidPeso molecular:277.15Foliglurax
CAS:Foliglurax is a highly selective brain-penetrant metabotropic glutamate receptor 4 positive allosteric modulator (mGluR4 PAM) (EC50: 79 nM).Fórmula:C23H23N3O3SPureza:98%Cor e Forma:SolidPeso molecular:421.51N,N-Dipropyldopamine (hydrobromide)
CAS:N,N-Dipropyldopamine is a dopamine agonist reducing DOPA and locomotion in rats and mice, reversible by spiroperidol.Fórmula:C14H24BrNO2Cor e Forma:SolidPeso molecular:318.255ML337
CAS:ML337 is a negative allosteric modulator of mGlu3 with an IC50 of 593 nM.Fórmula:C21H20FNO3Pureza:99.83%Cor e Forma:SolidPeso molecular:353.39Ref: TM-T23003
100mgA consultar1mg34,00€5mg60,00€1mL*10mM (DMSO)72,00€10mg92,00€25mg195,00€50mg293,00€VU6001376
CAS:VU6001376 is an effective and selective positive allosteric modulator of the metabotropic glutamate receptor 4 (EC50: 50.1 nM).Fórmula:C18H14F2N6OSPureza:98%Cor e Forma:SolidPeso molecular:400.41NS 1209
CAS:NS 1209 (SPD 502) is a AMPA receptor antagonist.Fórmula:C24H27N4NaO7SPureza:98%Cor e Forma:SolidPeso molecular:538.55LY382884
CAS:LY382884 is a selective and potent GluR5 kainate receptor antagonist with anxiolytic activity.LY382884 blocks blockade of mossy fibre LTP induction.Fórmula:C18H23NO4Pureza:98.32% - 98.71%Cor e Forma:SolidPeso molecular:317.38MFZ 10-7 hydrochloride
CAS:MFZ 10-7 hydrochloride is a highly potent and selective negative allosteric modulator of mGluR5 NAMFórmula:C15H10ClFN2Pureza:98%Cor e Forma:SolidPeso molecular:272.71Ro 67-4853
CAS:Ro 67-4853 is a positive allosteric modulator of mGluR1, selectively enhancing the response to the agonist (S)-3,5-dihydroxy-phenylglycine (DHPG).Fórmula:C19H19NO4Pureza:98.57%Cor e Forma:SolidPeso molecular:325.36VU0155041 sodium
CAS:VU0155041 sodium is a positive allosteric modulator of mGluR4 that promotes extinction in male rats.Fórmula:C14H14Cl2NNaO3Pureza:98%Cor e Forma:White SolidPeso molecular:338.16VU0240382
CAS:VU0240382 is a selective positive allosteric modulators of metabotropic glutamate receptor subtype 5.Fórmula:C17H13NOCor e Forma:SolidPeso molecular:247.29Methoxy-PEPy
CAS:Methoxy-PEPy is a potent and selective mGlu5 receptor inhibitor with an IC50 value of 1 nM.Fórmula:C13H10N2OPureza:98.66%Cor e Forma:SolidPeso molecular:210.23HexylHIBO
CAS:HexylHIBO is a type I mGluR antagonist that inhibits mGlu1a and mGlu5a, with Kb values of 140 and 110 μM, respectively.HexylHIBO decreases sEPSC in rats.Fórmula:C12H20N2O4Pureza:99.55%Cor e Forma:SolidPeso molecular:256.3(S)-MCPG
CAS:(S)-MCPG is the active isomer of (RS)-MCPG, non-selective group I/group II metabotropic glutamate receptor antagonist.Fórmula:C10H11NO4Pureza:98.72%Cor e Forma:SolidPeso molecular:209.20(1R,2S)-VU0155041
CAS:(1R,2S)-VU0155041 is the cis regioisomer of VU0155041 and a partial agonist of mGluR4.Fórmula:C14H15Cl2NO3Pureza:98.85%Cor e Forma:SolidPeso molecular:316.18TC-N 22A
CAS:TC-N 22A is a strong, selective, oral active mGlu4 forward allosteric regulator (PAM) that can cross the blood-brain barrier.Fórmula:C14H13N5SPureza:99.95%Cor e Forma:Orange SolidPeso molecular:283.35BMT-145027
CAS:BMT-145027 is a positive allosteric modulator of mGluR5 without inherent agonist activity (EC50 = 47 nM).Fórmula:C23H14ClF3N4Pureza:99.62%Cor e Forma:SolidPeso molecular:438.83DMeOB
CAS:DMeOB (3,3'-Dimethoxybenzaldazine) is a negative regulator with mGluR5 agonist activity and is used in the study of neurological disorders.Fórmula:C16H16N2O2Pureza:99.84%Cor e Forma:SolidPeso molecular:268.31(S)-3,5-DHPG
CAS:group I mGlu receptor agonistFórmula:C8H9NO4Pureza:99.60%Cor e Forma:White SolidPeso molecular:183.16HTL14242
CAS:HTL14242 is a mGlu5 Negative Allosteric Modulator.Fórmula:C16H8ClFN4Cor e Forma:SolidPeso molecular:310.71TASP0433864
CAS:TASP0433864 enhances mGlu2 activity; EC50: 199 nM (human), 206 nM (rat); not an agonist.Fórmula:C18H23N3O3Pureza:98%Cor e Forma:SolidPeso molecular:329.39(RS)-PPG
CAS:(RS)-PPG: Potent, selective III mGluRs agonist; EC50s: hmGluR4a 5.2μM, hmGluR6 4.7μM, hmGluR7b 185μM, hmGluR8a 0.2μM; neuroprotective, anticonvulsive.Fórmula:C8H10NO5PPureza:98%Cor e Forma:SolidPeso molecular:231.14CPPHA
CAS:CPPHA, a positive allosteric modulator of glutamate receptors mGluR5 and mGluR1, is commonly used in development for central nervous system diseases.Fórmula:C22H15ClN2O4Pureza:99.7%Cor e Forma:White SolidPeso molecular:406.82VU0431316
CAS:VU0431316 is a negative mGlu5 allosteric modulator. It has activity in a mouse model of anxiety.Fórmula:C14H9ClN6O2Pureza:98%Cor e Forma:SolidPeso molecular:328.71DCG-IV
CAS:DCG-IV: Class II mGluR agonist; anticonvulsant; neuroprotective; EC50: mGlu2R-0.35μM, mGlu3R-0.09μM; antagonizes Group I/III mGluRs.Fórmula:C7H9NO6Pureza:98%Cor e Forma:SolidPeso molecular:203.15VU0410425
CAS:VU0410425 is a metabotropic glutamate receptor subtype 1 negative allosteric modulator.Fórmula:C19H16ClN3O3Pureza:98%Cor e Forma:SolidPeso molecular:369.8JNJ-40068782
CAS:JNJ-40068782 is a potent, selective and systemically active positive allosteric modulator of the mGlu2 receptor.Fórmula:C21H23N3OPureza:98%Cor e Forma:SolidPeso molecular:333.43AZ12216052
CAS:AZ12216052 is a GRP8 antagonist with anxiolytic and anti-inflammatory activity and can be used to study obesity and metabolic disorders.Fórmula:C19H22BrNOSPureza:99.78%Cor e Forma:SolidPeso molecular:392.35LY487379 hydrochloride
CAS:Positive allosteric modulator of mGlu2 receptorsFórmula:C21H20ClF3N2O4SPureza:98%Cor e Forma:SolidPeso molecular:488.91VU0361747
CAS:VU0361747 is a positive allosteric modulators (PAM) of metabotropic glutamate receptor subtype 5 (mGlu5).Fórmula:C19H17FN2O2Cor e Forma:SolidPeso molecular:324.35Auglurant
CAS:Auglurant is a novel and selective mGlu5 antagonist (IC50: 11 nM (rat) and an IC50: 14 nM (human)). Auglurant has an acceptable CNS penetration.Fórmula:C16H12FN5O2Cor e Forma:SolidPeso molecular:325.3Desmethyl-YM 298198
CAS:mGlu1-selective antagonistFórmula:C17H21ClN4OSPureza:98%Cor e Forma:SolidPeso molecular:364.89Foliglurax monohydrochloride
CAS:Foliglurax monohydrochloride, an antiparkinsonian, is a selective brain-penetrant mGluR4 PAM with an EC50 of 79 nM.Fórmula:C23H24ClN3O3SCor e Forma:SolidPeso molecular:457.97L-CCG-l
CAS:group II metabotropic glutamate receptor agonistFórmula:C6H9NO4Pureza:98%Cor e Forma:SolidPeso molecular:159.14(1S,3R)-ACPD
CAS:(1S,3R)-ACPD is a group I and II mGlu receptor agonist.Fórmula:C7H11NO4Pureza:98%Cor e Forma:SolidPeso molecular:173.17VU0404251
CAS:VU0404251 is a positive allosteric modulator of mGlu5.Fórmula:C19H23FN2O2Cor e Forma:SolidPeso molecular:330.4Mavoglurant racemate
CAS:Mavoglurant is a novel, non-competitive mGlu5 receptor antagonist. Mavoglurant (racemate) is the racemate of mavoglurant.Fórmula:C19H23NO3Pureza:98%Cor e Forma:SolidPeso molecular:313.39ACPT-II
CAS:metabotropic receptor antagonistFórmula:C8H11NO6Pureza:98%Cor e Forma:SolidPeso molecular:217.18LY456066
CAS:LY456066 is a mGluR1 receptor-selective, negative allosteric modulator.Fórmula:C19H23N3OSPureza:98%Cor e Forma:SolidPeso molecular:341.47Z-Cyclopentyl-AP4
CAS:Group III mGlu receptor agonistFórmula:C6H12NO5PPureza:98%Cor e Forma:SolidPeso molecular:209.14DL-AP4 Sodium salt
CAS:Broad spectrum EAA ligandFórmula:C4H10NNaO5PPureza:98%Cor e Forma:SolidPeso molecular:206.09DFMTI
CAS:DFMTI can completely block the rmGlu1 L757V glutamate response.Fórmula:C20H18F2N4OCor e Forma:SolidPeso molecular:368.38GRN-529
CAS:GRN-529 is a selective negative allosteric modulator of the mGluR5 receptor.Fórmula:C22H15F2N3O2Pureza:98%Cor e Forma:SolidPeso molecular:391.37UPF-523
CAS:group I metabotropic glutamate receptors (mGlu1a) antagonistFórmula:C11H11NO4Pureza:98%Cor e Forma:White SolidPeso molecular:221.21JNJ-46356479
CAS:JNJ-46356479: Selective, oral mGlu2 receptor PAM, EC50=78 nM, Emax=256%.Fórmula:C22H22F5N5Cor e Forma:SolidPeso molecular:451.44MAP4
CAS:metabotropic glutamate receptor modulatorFórmula:C5H12NO5PPureza:98%Cor e Forma:SolidPeso molecular:197.13VU0366248
CAS:VU0366248 is a mGlu5 negative allosteric modulator.Fórmula:C14H7ClF2N2OPureza:98%Cor e Forma:SolidPeso molecular:292.673,3'-Difluorobenzaldazine
CAS:allosteric potentiator of mGlu5Fórmula:C14H10F2N2Pureza:98%Cor e Forma:SolidPeso molecular:244.24VU 0469650
CAS:VU 0469650 is a potent and selective negative allosteric modulator of mGluR1 (IC50 = 99 nM).Fórmula:C22H28N4OPureza:98.03%Cor e Forma:SolidPeso molecular:364.48Ref: TM-T29118
1mg42,00€5mg79,00€1mL*10mM (DMSO)90,00€10mg108,00€25mg210,00€50mg313,00€100mg464,00€200mg640,00€(RS)-MCPG disodium salt
CAS:group I/group II metabotropic glutamate receptor antagonistFórmula:C10H11NNaO4Pureza:98%Cor e Forma:SolidPeso molecular:232.19
