AChR
Os inibidores do receptor de acetilcolina (AChR) são compostos que bloqueiam a atividade dos receptores de acetilcolina, essenciais para a neurotransmissão nos sistemas nervosos central e periférico. Os AChRs desempenham um papel vital na contração muscular, memória e funções cognitivas. Os inibidores de AChRs são usados para estudar condições como miastenia gravis, doença de Alzheimer e outros distúrbios neurológicos. Ao modular a atividade dos AChRs, esses inibidores podem ajudar a desvendar as complexidades da sinalização colinérgica no cérebro. Na CymitQuimica, oferecemos uma gama de inibidores de AChRs para apoiar sua pesquisa em neurociência, farmacologia e doenças neurodegenerativas.
Foram encontrados 624 produtos para "AChR".
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TAK-071
CAS:TAK-071 is a potent, novel and highly selective modulator of muscarinic acetylcholine receptor 1 (M1R) positive allosteric(EC50 : 520 nM).Fórmula:C24H24FN3O3Pureza:98.02% - 99.82%Cor e Forma:SolidPeso molecular:421.4641Procainamide hydrochloride
CAS:Procainamide Hydrochloride (Procapan) is the hydrochloride salt form of procainamide, an amide derivative exhibiting class 1A antiarrhythmic property and analogFórmula:C13H22ClN3OPureza:99.83% - 99.97%Cor e Forma:SolidPeso molecular:271.786MK-7622
CAS:MK-7622 (M1 receptor modulator) is a modulator of muscarinic M1 receptor positive allosteric.Fórmula:C25H25N3O2Pureza:99.77% - 99.8%Cor e Forma:SolidPeso molecular:399.4849Carbachol
CAS:Carbachol (Carbamoylcholine chloride), an analog of acetylcholine, serves as a valuable tool in the investigation of various physiological responses mediated by nicotinic (nAChR) and muscarinic (mAChR) acetylcholine receptors. These responses include smooth muscle contraction, gut motility, and neuronal signaling. Known for its agonistic properties, Carbachol activates both nAChR and mAChR, with reported Ki values ranging from 10 to 10,000 nM for different receptor types and experimental preparations.Fórmula:C6H15ClN2O2Pureza:99.81% - >99.99%Cor e Forma:SolidPeso molecular:182.65VU 0365114
CAS:VU 0365114 is a positive allosteric modulator of mAChR M5 and increases ACh-induced calcium mobilization(EC50: 2.7 μM).Fórmula:C22H14F3NO3Pureza:99.86%Cor e Forma:Red SolidPeso molecular:397.35Promethazine hydrochloride
CAS:Promethazine HCl: First-gen antihistamine, H1 and mACh blocker, affects 5-HT2A/C, D2, α1 receptors.Fórmula:C17H20N2S·HClPureza:99.85%Cor e Forma:Crystals In Water Has A Ph Of 3 5-5 0 (Ntp 1992)Peso molecular:320.88Solifenacin succinate
CAS:Solifenacin succinate (YM905) is a quinuclidine and tetrahydroisoquinoline derivative and selective M3 muscarinic antagonist, which is used as a urologic agent.Fórmula:C23H26N2O2·C4H6O4Pureza:99.85% - 99.98%Cor e Forma:SolidPeso molecular:480.56Acetamiprid
CAS:Acetamiprid: nAChR agonist, global neonicotinoid insecticide linked to neuromuscular/reproductive issues.Fórmula:C10H11ClN4Pureza:99.66% - 99.89%Cor e Forma:White PowderPeso molecular:222.674Nebracetam hydrochloride
CAS:Nebracetam HCl (WEB 1881 FU) is an M1-muscarinic agonist nootropic, increasing intracellular Ca2+ with an EC50 of 1.59 mM.Fórmula:C12H17ClN2OPureza:99.42%Cor e Forma:SolidPeso molecular:240.729bPiDDB
CAS:bPiDDB (N,N'-Dodecylbis-Picolinium Bromide) is a nicotinic receptor (nAChR) antagonist.Fórmula:C24H38Br2N2Pureza:99.71%Cor e Forma:White SolidPeso molecular:514.38Benzethonium chloride
CAS:Benzethonium chloride (Quatrachlor) is a synthetic quaternary ammonium salt with surfactant, antiseptic, and broad spectrum antimicrobial properties.Fórmula:C27H42ClNO2Pureza:99.91%Cor e Forma:White SolidPeso molecular:448.081Dicyclomine hydrochloride
CAS:Dicyclomine hydrochloride is a muscarinic antagonist used as an antispasmodic and in urinary incontinence.Fórmula:C19H36ClNO2Pureza:99.81%Cor e Forma:SolidPeso molecular:345.948Pirenzepine dihydrochloride
CAS:Pirenzepine dihydrochloride (LS519) is a selective M1 muscarinic receptor antagonist, inhibiting gastric secretion.Fórmula:C19H21N5O2·2HClPureza:99.48% - 99.62%Cor e Forma:SolidPeso molecular:424.32DL-trihexyphenidyl hydrochloride
CAS:DL-trihexyphenidyl hydrochloride (Trihexyphenidyl HCl) is a muscarinic antagonist.Fórmula:C20H32ClNOPureza:99.63% - 99.71%Cor e Forma:White SolidPeso molecular:337.93Bethanechol chloride
CAS:Bethanechol chloride: muscarinic agonist, boosts smooth muscle tone, used post-abdominal surgery & for urinary retention; may cause hypotension & bronchospasm.Fórmula:C7H17N2O2·ClPureza:95% - 99.98%Cor e Forma:White SolidPeso molecular:196.68(Rac)-ABT-202 dihydrochloride
CAS:(Rac)-ABT-202 dihydrochloride is a racemate of ABT-202. ABT-202 is an nicotinic acetylcholine receptors (nAChRs) agonist and can be used as an analgesic.Fórmula:C9H15Cl2N3Pureza:98.72%Cor e Forma:SolidPeso molecular:236.142Adiphenine hydrochloride
CAS:Adiphenine hydrochloride (Patrovina), a nicotinic receptor inhibitor, can be used as an antispasmodic drug.Fórmula:C20H26ClNO2Pureza:97.76% - 99.53%Cor e Forma:White Or Almost White PowderPeso molecular:347.879Diphenmanil methylsulfate
CAS:Diphenmanil methylsulfate (Diphemanil mesylate), a quaternary ammonium anticholinergic, binds muscarinic acetylcholine receptors.Fórmula:C21H27NO4SPureza:98% - 99.27%Cor e Forma:White SolidPeso molecular:389.5088-Aminoadenine
CAS:8-Aminoadenine (7H-purine-6,8-diamine) is a ligand for Adenine Receptor with Ki of 0.0341 μM.Fórmula:C5H6N6Pureza:99.82%Cor e Forma:SolidPeso molecular:150.14Lysipressin acetate(50-57-7(fb_acetate))
CAS:Lysipressin acetate (50-57-7), triggers rabbit bladder contraction & activates adenylate cyclase, is an antidiuretic in pigs & marsupials.Fórmula:C48H69N13O14S2Pureza:98.08%Cor e Forma:SolidPeso molecular:1116.27
