Células - tronco e Derivados

Os inibidores de células-tronco são compostos que visam especificamente as vias de sinalização e proteínas envolvidas na manutenção, diferenciação e proliferação de células-tronco. Esses inibidores são cruciais para compreender a biologia das células-tronco e para desenvolver estratégias para manipular células-tronco para fins terapêuticos, como medicina regenerativa e tratamento do câncer. Ao controlar o destino das células-tronco, esses inibidores podem ajudar a orientar a diferenciação das células-tronco em tipos celulares específicos ou prevenir o crescimento celular indesejado. Na CymitQuimica, oferecemos uma seleção de inibidores de células-tronco de alta qualidade para apoiar sua pesquisa em biologia de células-tronco, biologia do desenvolvimento e medicina regenerativa.

Subcategorias de "Células - tronco e Derivados"

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Foram encontrados 695 produtos de "Células - tronco e Derivados"

Pureza (%)

100

produtos por página.

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GSK429286A
CAS:
- 864082-47-3
GSK429286A (RHO-15) is a specific inhibitor of ROCK1/2 (IC50: 14/63 nM).
Fórmula:C₂₁H₁₆F₄N₄O₂
Pureza:97.68% - 98.49%
Cor e Forma:Solid
Peso molecular:432.37
Ref: TM-T2633
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AS-252424
CAS:
- 900515-16-4
AS-252424 is a potent and selective inhibitor of PI3Kγ with IC50 of 33 nM; >10 fold selectivity for PI3Kγ versus PI3Kα.
Fórmula:C₁₄H₈FNO₄S
Pureza:99.06% - 99.09%
Cor e Forma:Solid
Peso molecular:305.28
Ref: TM-T6208
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Fedratinib
CAS:
- 936091-26-8
Fedratinib (TG-101348) (TG101348) is an ATP-competitive inhibitor of JAK2 (IC50: 3 nM) with significantly less potent activity against JAK3.
Fórmula:C₂₇H₃₆N₆O₃S
Pureza:97.31% - 99.96%
Cor e Forma:Solid
Peso molecular:524.68
Ref: TM-T1995
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Silmitasertib
CAS:
- 1009820-21-6
Silmitasertib (CX-4945) is a potent, orally bioavailable inhibitor of casein kinase 2 (CK2; Ki: 0.38 nM).
Fórmula:C₁₉H₁₂ClN₃O₂
Pureza:98% - 99.90%
Cor e Forma:Solid
Peso molecular:349.77
Ref: TM-T2259
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Brevilin A
CAS:
- 16503-32-5
Brevilin A, a sesquiterpene from Centipeda minima, hinders JAK and blocks STAT3 (IC50=10.6μM), inducing apoptosis and autophagy in cancer cells.
Fórmula:C₂₀H₂₆O₅
Pureza:99.97% - >99.99%
Cor e Forma:Solid
Peso molecular:346.42
Ref: TM-T4672
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BMS986260
CAS:
- 2001559-19-7
BMS-986260 is a selective, and orally bioavailable TGFβR1 inhibitor(IC50 = 1.6 nM).
Fórmula:C₁₈H₁₂ClFN₆O
Pureza:97.67%
Cor e Forma:Solid
Peso molecular:382.78
Ref: TM-T8730
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CP21R7
CAS:
- 125314-13-8
CP21 is a specific GSK3β inhibitor, used to activate stem cells for differentiation, often paired with BMP4 for mesodermal fate.
Fórmula:C₁₉H₁₅N₃O₂
Pureza:96.14% - 99.16%
Cor e Forma:Solid
Peso molecular:317.34
Ref: TM-T3684
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RO8191
CAS:
- 691868-88-9
RO8191 (CDM-3008) (CDM-3008) is an agonist of interferon (IFN) receptor.
Fórmula:C₁₄H₅F₆N₅O
Pureza:98% - 98.85%
Cor e Forma:Solid
Peso molecular:373.21
Ref: TM-T22142
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SH5-07
CAS:
- 1456632-41-9
SH5-07 is a hydroxamic acid-based Stat3 inhibitor (IC50: 3.9 μM).
Fórmula:C₂₉H₂₈F₅N₃O₅S
Pureza:95.54%
Cor e Forma:Solid
Peso molecular:625.61
Ref: TM-TQ0052
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IHR-1
CAS:
- 548779-60-8
IHR-1, a Smo inhibitor (IC50 7.6 nM), blocks Hedgehog pathway, not Wnt/Notch, and prevents Smo in primary cilium.
Fórmula:C₂₀H₁₂Cl₄N₂O₂
Pureza:97.02%
Cor e Forma:Solid
Peso molecular:454.13
Ref: TM-T24159
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Kartogenin
CAS:
- 4727-31-5
Kartogenin (KGN) is an activator of the smad4/smad5 pathway, and promotes the selective differentiation of multipotent mesenchymal stem cells into chondrocytes.
Fórmula:C₂₀H₁₅NO₃
Pureza:96.25% - 97.79%
Cor e Forma:Solid
Peso molecular:317.34
Ref: TM-T1748
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BMP signaling agonist sb4
CAS:
- 100874-08-6
BMP signaling agonist sb4 (SB 4) is an agonist of benzoxazole bone morphogenetic protein (BMP) signaling (EC50 :74 nM)
Fórmula:C₁₄H₁₀BrNOS
Pureza:99.48% - 99.805%
Cor e Forma:Solid
Peso molecular:320.2
Ref: TM-T7799
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2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide
CAS:
- 1258292-64-6
2,6-Dichloro-N-(2-(cyclopropanecarboxamido)pyridin-4-yl)benzamide (GDC046), a potent lead analog, has good kinase selectivity and physicochemical properties.
Fórmula:C₁₆H₁₃Cl₂N₃O₂
Pureza:98.77%
Cor e Forma:Solid
Peso molecular:350.2
Ref: TM-T22338
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RKI1313
CAS:
- 1342276-76-9
RKI1313 (RKI-1313) was a selective inhibitor for ROCK-dependent signaling, cytoskeletal changes, anchorage-independent colony formation, migration, and invasion
Fórmula:C₁₇H₁₆N₄O₂S
Pureza:99.53% - ≥95%
Cor e Forma:Solid
Peso molecular:340.4
Ref: TM-T2011
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Pacritinib hydrochloride
CAS:
- 1228923-43-0
Pacritinib HCl: strong JAK2/Wild-type & JAK2V617F inhibitor (IC50: 23/19 nM), used in AML & MF research.
Fórmula:C₂₈H₃₂N₄O₃·xClH
Cor e Forma:Solid
Ref: TM-T64283
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Ritlecitinib tosylate
CAS:
- 2192215-81-7
Ritlecitinib (PF-06651600) is a potent, selective JAK3 inhibitor with proven in vivo efficacy, low clearance, and has undergone clinical trials.
Fórmula:C₂₂H₂₇N₅O₄S
Cor e Forma:Solid
Peso molecular:457.549
Ref: TM-T69822
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AT13148
CAS:
- 1056901-62-2
AT13148 is an oral-active and ATP-competitive, multi-AGC kinase inhibitor for Akt1/2/3, p70S6K, PKA, and ROCKI/II.
Fórmula:C₁₇H₁₆ClN₃O
Pureza:98.04% - ≥95%
Cor e Forma:Solid
Peso molecular:313.78
Ref: TM-T2482
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(E/Z)-GO289
CAS:
- 694522-87-7
(E/Z)-GO289, which strongly lengthened circadian period, is a potent and selective inhibitor of CK2.
Fórmula:C₁₇H₁₅BrN₄O₂S
Pureza:98.1%
Cor e Forma:Solid
Peso molecular:419.3
Ref: TM-T9356
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FH535
CAS:
- 108409-83-2
FH535, a Wnt/β-catenin signaling and PPAR inhibitor, exhibits anti-tumor activities.
Fórmula:C₁₃H₁₀Cl₂N₂O₄S
Pureza:98.25% - 99.5%
Cor e Forma:Solid
Peso molecular:361.2
Ref: TM-T2413
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KY02111
CAS:
- 1118807-13-8
KY02111 facilitates differentiation of hPSCs to cardiomyocytes by inhibiting Wnt signaling, maybe affect downstream of GSK3β and APC.
Fórmula:C₁₈H₁₇ClN₂O₃S
Pureza:97.71% - 98.3%
Cor e Forma:Solid
Peso molecular:376.86
Ref: TM-T2052