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Células - tronco e Derivados

Células - tronco e Derivados

Os inibidores de células-tronco são compostos que visam especificamente as vias de sinalização e proteínas envolvidas na manutenção, diferenciação e proliferação de células-tronco. Esses inibidores são cruciais para compreender a biologia das células-tronco e para desenvolver estratégias para manipular células-tronco para fins terapêuticos, como medicina regenerativa e tratamento do câncer. Ao controlar o destino das células-tronco, esses inibidores podem ajudar a orientar a diferenciação das células-tronco em tipos celulares específicos ou prevenir o crescimento celular indesejado. Na CymitQuimica, oferecemos uma seleção de inibidores de células-tronco de alta qualidade para apoiar sua pesquisa em biologia de células-tronco, biologia do desenvolvimento e medicina regenerativa.

Subcategorias de "Células - tronco e Derivados"

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Foram encontrados 693 produtos de "Células - tronco e Derivados"

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  • GDC-4379
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    GDC-4379

    CAS:
    <p>GDC-4379 is a JAK1 inhibitor that can be used to study asthma.</p>
    Fórmula:C21H18ClF2N7O3
    Cor e Forma:Solid
    Peso molecular:489.86

    Ref: TM-T63280

  • CP-690550A
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    CP-690550A

    CAS:
    <p>Cp-690550a is a novel JAK3 inhibitor, which is used to treat rheumatoid arthritis, graft rejection, psoriasis, and other immune-mediated diseases.</p>
    Fórmula:C15H21N5O2
    Cor e Forma:Solid
    Peso molecular:303.36

    Ref: TM-T31074

  • Yhhu-3792
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    Yhhu-3792

    CAS:
    <p>Yhhu-3792 activates Notch, boosts Hes3/Hes5, enhances NSC renewal, expands NSC pool, and may improve memory.</p>
    Fórmula:C24H24N4O2
    Cor e Forma:Solid
    Peso molecular:400.47

    Ref: TM-T61930

  • Thi-DPPY
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    Thi-DPPY

    CAS:
    <p>Thi-DPPY: Potent JAK3/BTK inhibitor (IC50: 1.38/62.4 nM), anti-proliferative, anti-inflammatory, potential in IPF research.</p>
    Fórmula:C28H28ClN5O4S
    Cor e Forma:Solid
    Peso molecular:566.07

    Ref: TM-T64008

  • Peficitinib hydrobromide
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    Peficitinib hydrobromide

    CAS:
    <p>Peficitinib hydrobromide is used in the treatment of Psoriasis and Rheumatoid Arthritis.</p>
    Fórmula:C18H23BrN4O2
    Cor e Forma:Solid
    Peso molecular:407.312

    Ref: TM-T33905

  • PF-00956980
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    PF-00956980

    CAS:
    <p>PF-00956980: reversible JAK inhibitor, IC50: JAK1 (2.2μM), JAK2 (23.1μM), JAK3 (59.9μM), for lung/skin inflammation research.</p>
    Fórmula:C18H26N6O
    Cor e Forma:Solid
    Peso molecular:342.44

    Ref: TM-T71089

  • γ-Secretase modulator 11
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    γ-Secretase modulator 11

    CAS:
    <p>5-{8-[(3,4'-Difluoro[1,1'-biphenyl]-4-yl)methoxy]-2-methylimidazo[1,2-a]pyridin-3-yl}-N-methylpyridine-2-carboxamide (1o) exhibited high in vitro potency and</p>
    Fórmula:C28H22F2N4O2
    Cor e Forma:Solid
    Peso molecular:484.5

    Ref: TM-T63216

  • SYK/JAK-IN-1
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    SYK/JAK-IN-1

    CAS:
    <p>SYK/JAK-IN-1 is a dual SYK/JAK inhibitor with IC50 values of less than 5 nM for both SYK and JAK2.</p>
    Fórmula:C24H26N8O3
    Cor e Forma:Solid
    Peso molecular:474.52

    Ref: TM-T63086

  • TUL01101
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    TUL01101

    CAS:
    <p>TUL01101, a selective oral JAK1 inhibitor (IC50: 3 nM), also targets JAK2, JAK3, TYK2; for rheumatoid arthritis research.</p>
    Fórmula:C22H25F2N5O2
    Cor e Forma:Solid
    Peso molecular:429.46

    Ref: TM-T73392

  • JAK3i
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    JAK3i

    CAS:
    <p>JAK3i selectively inhibits JAK3 kinase, targeting the second, vital wave of STAT5 phosphorylation for T cell growth.</p>
    Fórmula:C18H15FN4O3
    Pureza:98.61% - 99.81%
    Cor e Forma:Solid
    Peso molecular:354.34

    Ref: TM-T27650

  • TK4b
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    TK4b

    CAS:
    <p>TK4b, a JAK inhibitor, targets leukemia/lymphoid diseases, with IC50s: 18.42 nM (JAK3) &amp; 19.40 nM (JAK2).</p>
    Fórmula:C21H22N2O2
    Cor e Forma:Solid
    Peso molecular:334.41

    Ref: TM-T61020

  • BRD0209
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    BRD0209

    CAS:
    <p>BRD0209 is a highly selective and potent GSK3 inhibitor.</p>
    Fórmula:C22H25N3O
    Pureza:99.92%
    Cor e Forma:Solid
    Peso molecular:347.45

    Ref: TM-T26894

  • JA310
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    JA310

    CAS:
    <p>JA310 is a highly selective inhibitor of the MST3 kinase, demonstrating significant cellular potency with an EC50 value of 106 nM [1].</p>
    Fórmula:C17H19N7O
    Cor e Forma:Solid
    Peso molecular:337.38

    Ref: TM-T86752

  • RR-11a
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    RR-11a

    CAS:
    <p>RR-11a is a synthetic enzyme Legumain inhibitor.</p>
    Fórmula:C24H28N6O10
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:560.51

    Ref: TM-T12769

  • BPN-15606
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    BPN-15606

    CAS:
    <p>BPN-15606, an oral γ-secretase modulator, reduces Aβ42/Aβ40 with IC50 of 7/17 nM; promising PK/PD, lowers Aβ in rodent CNS.</p>
    Fórmula:C23H23FN6O
    Cor e Forma:Solid
    Peso molecular:418.47

    Ref: TM-T10589L

  • Peficitinib hydrochloride
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    Peficitinib hydrochloride

    CAS:
    <p>Peficitinib HCl (ASP015K) is an oral JAK inhibitor with IC50s: JAK1 (3.9 nM), JAK2 (5.0 nM), JAK3 (0.7 nM), Tyk2 (4.8 nM).</p>
    Fórmula:C18H23ClN4O2
    Cor e Forma:Solid
    Peso molecular:362.86

    Ref: TM-T61365

  • JAK-2/3-IN-2
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    JAK-2/3-IN-2

    CAS:
    <p>JAK-2/3-IN-2 (Compound 3h) is a potent JAK2 &amp; JAK3 inhibitor with IC50s of 23.85 nM (JAK2) &amp; 18.9 nM (JAK3).</p>
    Fórmula:C19H19ClN2OS
    Cor e Forma:Solid
    Peso molecular:358.89

    Ref: TM-T61323

  • Aβ42-IN-1 free base
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    Aβ42-IN-1 free base

    CAS:
    <p>Aβ42-IN-1 free base (compound 1v), an orally active γ-secretase modulator with high brain exposure, effectively lowers Aβ42 levels, exhibiting an IC 50 of 0.091</p>
    Fórmula:C29H26N4O2
    Pureza:98%
    Cor e Forma:Solid
    Peso molecular:462.54

    Ref: TM-T10443

  • JAK-IN-20
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    JAK-IN-20

    CAS:
    <p>JAK-IN-20: potent oral JAK1,2,3 inhibitor with IC50s 7, 5, 14 nM respectively, good pharmacokinetics, anti-inflammatory in vivo.</p>
    Fórmula:C28H30FN7O2
    Cor e Forma:Solid
    Peso molecular:515.58

    Ref: TM-T63581

  • ELN318463 racemate
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    ELN318463 racemate

    CAS:
    <p>ELN318463 racemate (ELN 318463 racemate) is the racemate of ELN318463 which is an amyloid precursor protein (APP) selective γ-secretase inhibitor.</p>
    Fórmula:C19H20BrClN2O3S
    Pureza:99.69%
    Cor e Forma:Solid
    Peso molecular:471.8

    Ref: TM-T11178L