Células - tronco e Derivados

Os inibidores de células-tronco são compostos que visam especificamente as vias de sinalização e proteínas envolvidas na manutenção, diferenciação e proliferação de células-tronco. Esses inibidores são cruciais para compreender a biologia das células-tronco e para desenvolver estratégias para manipular células-tronco para fins terapêuticos, como medicina regenerativa e tratamento do câncer. Ao controlar o destino das células-tronco, esses inibidores podem ajudar a orientar a diferenciação das células-tronco em tipos celulares específicos ou prevenir o crescimento celular indesejado. Na CymitQuimica, oferecemos uma seleção de inibidores de células-tronco de alta qualidade para apoiar sua pesquisa em biologia de células-tronco, biologia do desenvolvimento e medicina regenerativa.

Subcategorias de "Células - tronco e Derivados"

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Foram encontrados 693 produtos de "Células - tronco e Derivados"

Pureza (%)

100

produtos por página.

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XL413 xHCl
CAS:
- 1169562-71-3
BMS-863233 HCl is an ATP-competitive Cdc7 inhibitor (IC50: 3.4 nM) that is potent and selective.BMS-863233 HCl inhibited CK2 and PIM1 with IC50 values of 215
Fórmula:C₁₄H₁₂ClN₃O₂·xHCl
Pureza:99.37% - 99.67%
Cor e Forma:Solid
Peso molecular:326.18
Ref: TM-T71339
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BIP-135
CAS:
- 941575-71-9
BIP-135 is a potent and selective ATP-competitive GSK-3 inhibitor.
Fórmula:C₂₁H₁₃BrN₂O₃
Pureza:99.93%
Cor e Forma:Solid
Peso molecular:421.24
Ref: TM-T14613
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CID-5056270
CAS:
- 681173-76-2
CID-5056270 has anticancer activity and can inhibit lung cancer, anal cancer, bladder cancer, cervical cancer, vulvar cancer, penile cancer, Burkitt's lymphoma
Fórmula:C₁₇H₁₃N₃O₃S
Pureza:99.6%
Cor e Forma:Solid
Peso molecular:339.37
Ref: TM-T23888
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JAK1-IN-8
CAS:
- 1973485-18-5
JAK1-IN-8, a specific inhibitor of Janus kinase 1 (JAK1, IC50<500 nM).
Fórmula:C₂₂H₂₃FN₄O₃S
Pureza:98.4%
Cor e Forma:Solid
Peso molecular:442.51
Ref: TM-T35899
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JAK-STAT-IN-1
CAS:
- 1236666-76-4
JAK-STAT-IN-1 is a specific JAK-STAT inhibitor indicated for the study of autoimmune diseases.
Fórmula:C₂₁H₂₁N₅O₂
Pureza:99.59%
Cor e Forma:Solid
Peso molecular:375.42
Ref: TM-T78607
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EHT 1610
CAS:
- 1425945-60-3
EHT 1610 (EHT 5372) is a potent inhibitor of DYRK, with an IC50 of 0.36 nM and 0.59 nM for DYRK1A and DYRK1B, respectively.
Fórmula:C₁₈H₁₄FN₅O₂S
Pureza:98.59%
Cor e Forma:Solid
Peso molecular:383.4
Ref: TM-T15204
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ARN25068
CAS:
- 2649882-80-2
ARN25068 inhibits GSK-3β, FYN, DYRK1A kinases; acts in sub-micromolar range; combats tau hyperphosphorylation.
Fórmula:C₁₉H₁₈N₆S
Pureza:99.75%
Cor e Forma:Solid
Peso molecular:362.45
Ref: TM-T61360
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TT-10
CAS:
- 2230640-94-3
TT-10 (TAZ-K) activates YAP-TEAD; useful in heart disease with cardiomyocyte loss research.
Fórmula:C₁₁H₁₀FN₃OS₂
Pureza:99.29%
Cor e Forma:Solid
Peso molecular:283.35
Ref: TM-T69760
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GSK-3 Inhibitor XIII
CAS:
- 404828-14-4
GSK-3 InhibitorXIII, an ATP-competitive GSK-3 inhibitor (Ki: 24 nM), can be used to study diabetes and obesity.
Fórmula:C₁₈H₁₅N₅
Pureza:99.85% - 99.86%
Cor e Forma:Solid
Peso molecular:301.35
Ref: TM-T78578
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IHMT-MST1-58
CAS:
- 2414484-25-4
IHMT-MST1-58 is a STE20-like protein 1 kinase (MST1) inhibitor (IC50:23 nM) with high efficiency, selectivity and oral activity.
Fórmula:C₂₁H₂₂N₆O₃S
Pureza:98.31% - 99.92%
Cor e Forma:Solid
Peso molecular:438.5
Ref: TM-T62512
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Miclxin
CAS:
- 2494198-61-5
Miclxin (DS37262926) is a novel MIC60 inhibitor that induces apoptosis through mitochondrial stress in mutant tumor cells via β-catenin.Miclxin is a potent
Fórmula:C₂₆H₂₇N₅O₂
Pureza:99.17% - 99.99%
Cor e Forma:Solid
Peso molecular:441.52
Ref: TM-T73415
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AS 1892802
CAS:
- 928320-12-1
AS 1892802, a ROCK inhibitor: IC50 - 52nM (hROCK2), 57nM (rROCK2), 122nM (hROCK1). Fast antinociceptive effect similar to Tramadol, Diclofenac.
Fórmula:C₂₀H₁₉N₃O₂
Pureza:99.86%
Cor e Forma:Solid
Peso molecular:333.38
Ref: TM-T22037
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Wnt/β-catenin agonist 4
CAS:
- 912784-79-3
Wnt/β-catenin agonist 4 is an agonist of Wnt that activates Wnt/β-catenin signaling and directs signaling.
Fórmula:C₁₆H₁₅FN₄O₂
Pureza:99.61%
Cor e Forma:Solid
Peso molecular:314.31
Ref: TM-T60803
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SJ000063181
CAS:
- 945189-68-4
SJ000063181 activates BMP signaling (EC50 ≤1μM), usable as probe in zebrafish embryos.
Fórmula:C₁₄H₁₄ClFN₂O₂
Pureza:99.94%
Cor e Forma:Solid
Peso molecular:296.72
Ref: TM-T60644
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ABC1183
CAS:
- 1042735-18-1
ABC1183, an oral diaminothiazole, inhibits GSK3α/β, CDK9, hinders cancer cell growth, induces G2/M arrest, and modulates phosphorylation.
Fórmula:C₁₈H₁₄N₄OS
Pureza:98.92%
Cor e Forma:Solid
Peso molecular:334.39
Ref: TM-T23601
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Rho-Kinase-IN-1
CAS:
- 1035094-83-7
Rho-Kinase-IN-1: ROCK inhibitor, Ki of 30.5 nM (ROCK1) & 3.9 nM (ROCK2), used in research for diseases linked to cell overgrowth and inflammation.
Fórmula:C₂₀H₂₄N₄S
Pureza:99.8%
Cor e Forma:Solid
Peso molecular:352.5
Ref: TM-T12721
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STS-E412
CAS:
- 1609980-39-3
STS-E412 is a tissue-protective and selective EPOR/CD131 receptor activator for the study of neurological disorders.
Fórmula:C₁₅H₁₅ClN₄O₂
Pureza:99.01%
Cor e Forma:Solid
Peso molecular:318.76
Ref: TM-T24840
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FzM1.8
CAS:
- 2204290-85-5
FzM1.8: allosteric FZD4 agonist, pEC50=6.4; boosts TCF/LEF, activates WNT/β-catenin with no WNT needed.
Fórmula:C₁₈H₁₄N₂O₄
Pureza:99.89%
Cor e Forma:Solid
Peso molecular:322.31
Ref: TM-T15363
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STAT6-IN-3
CAS:
- 371919-80-1
STAT6-IN-3 (Compound 18a) serves as an inhibitor of STAT6 with an IC50 value of 44 nM, specifically targeting the Src Homology 2 (SH2) domain.
Fórmula:C₃₂H₃₅IN₃O₇P
Pureza:98%
Cor e Forma:Solid
Peso molecular:731.51
Ref: TM-T79186
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Antitumor agent-73
CAS:
- 2812356-72-0
Antitumor Agent-73, derived from Diosgenin, blocks STAT3 and activates Pdia3, showing strong cancer cell line efficacy.
Fórmula:C₅₀H₈₂BrO₄P
Pureza:98%
Cor e Forma:Solid
Peso molecular:858.06
Ref: TM-T74950