c-Fms
Os inibidores de c-Fms têm como alvo o Receptor do Fator Estimulador de Colônias-1 (c-Fms), uma tirosina quinase envolvida na regulação de macrófagos e outras células imunológicas. A sinalização de c-Fms desempenha um papel na proliferação, diferenciação e sobrevivência dessas células. A desregulação do c-Fms está associada a doenças como câncer, condições inflamatórias e osteoporose. Na CymitQuimica, oferecemos inibidores de c-Fms para apoiar sua pesquisa em imunologia, oncologia e doenças inflamatórias.
Foram encontrados 117 produtos para "c-Fms".
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CSF1R-IN-5
CAS:CSF1R-IN-5: Potent CSF1R inhibitor, may alter TAM/glioma inflammatory exchanges, potential cancer research tool. (WO2021197276A1, Compound 11)Fórmula:C22H19N7O3Cor e Forma:SolidPeso molecular:429.43Axl/Mer/CSF1R-IN-2
CAS:Axl/Mer/CSF1R-IN-2 (Comp 4) serves as an inhibitor for Axl, Mer, and CSF1R [1].Fórmula:C24H22F3N5O5Cor e Forma:SolidPeso molecular:517.46ARRY-382
CAS:ARRY-382 is a highly selective oral inhibitor of CSF-1R with an IC50 of 9 nM.Fórmula:C32H36N8O2Pureza:99.76%Cor e Forma:SolidPeso molecular:564.68c-Fms-IN-14
CAS:c-Fms-IN-14 (Example 76) is a potent inhibitor of the c-Fms kinase with an IC50 of 4 nM, utilized in cancer and autoimmune disease research [1].Fórmula:C26H24N6OPureza:98%Cor e Forma:SolidPeso molecular:436.51Ataquimast
CAS:Ataquimast is used in curing advanced receptor-positive breast cancer.Fórmula:C11H14ClN3OPureza:99.92%Cor e Forma:White SolidPeso molecular:239.7Axl/Mer/CSF1R-IN-1
CAS:Axl/Mer-IN-1 is a compound that functions as an inhibitor for Axl/Mer receptor tyrosine kinase (Axl/Mer RTK) and CSF1R, exhibiting dissociation constants (Kds)Fórmula:C25H24F3N5O5Cor e Forma:SolidPeso molecular:531.48Pimicotinib hydrochloride
CAS:Pimicotinib hydrochloride is an inhibitor of CSF1R, displaying antitumor activity.Fórmula:C22H25ClN6O3Cor e Forma:SolidPeso molecular:456.925Enrupatinib
CAS:Enrupatinib is an inhibitor of the colony stimulating factor 1 receptor (CSF1R), exhibiting antitumor activity.Fórmula:C27H26N6O3Cor e Forma:SolidPeso molecular:482.53Leustroducsin B
CAS:Leustroducsin B is a novel colony-stimulating factor (CSF) inducer extracted from Streptomyces platensis SANK 60191.Fórmula:C34H56NO10PCor e Forma:SolidPeso molecular:669.78c-Fms-IN-15
CAS:c-Fms-IN-15 (compound 8g) is a potent inhibitor of FMS kinase, with an IC50 of 563 nM.Fórmula:C29H28F3N7O2Cor e Forma:SolidPeso molecular:563.57GENZ-882706
CAS:GENZ-882706 is a potent colony stimulating factor-1 receptor (CSF-1R) Inhibitor.Fórmula:C26H25N5O3Pureza:98%Cor e Forma:SolidPeso molecular:455.51SJ-C1044
CAS:SJ-C1044 is an orally effective pan-RAF inhibitor demonstrating immunomodulatory and antitumor activities. It targets wild-type BRAF, wild-type CRAF, and BRAF(V600E) with IC50 values of 331, 257, and 187 nM, respectively. SJ-C1044 suppresses tumor cell proliferation by inhibiting kras activation and MEK-ERK phosphorylation. Additionally, it shows inhibition of VEGFR2, TIE2, and CSF1R, with IC50 values of 100, 23, and 235 nM respectively. The compound enhances the tumor immune microenvironment through inhibition of angiogenesis and modulation of macrophage function. SJ-C1044 is applicable for research in colorectal cancer.Fórmula:C25H14F7N7OCor e Forma:SolidPeso molecular:561.41JNJ-6204
CAS:JNJ-6204 is a deuterated compound that efficiently inhibits CSNK1D and CSNK1E.Fórmula:C19H11D6FN6OPureza:97.42% - 99.87%Cor e Forma:SolidPeso molecular:370.41Anti-CSF1R Antibody (8O797)
Anti-CSF1R Antibody (8O797) is a Mouse antibody targeting CSF1R. Anti-CSF1R Antibody (8O797) can be used in ELISA.Cor e Forma:Odour LiquidAnti-CSF1R Antibody (4Y587)
Anti-CSF1R Antibody (4Y587) is a Mouse antibody targeting CSF1R. Anti-CSF1R Antibody (4Y587) can be used in FCM.Cor e Forma:Odour LiquidAnti-CSF1R Antibody (2I506)
Anti-CSF1R Antibody (2I506) is a Mouse antibody targeting CSF1R. Anti-CSF1R Antibody (2I506) can be used in ELISA.Cor e Forma:Odour LiquidAnti-CSF1R Antibody (5C535)
Anti-CSF1R Antibody (5C535) is a Rabbit antibody targeting CSF1R. Anti-CSF1R Antibody (5C535) can be used in ELISA.Cor e Forma:Odour Liquid
