VEGFR
Os inibidores do Receptor do Fator de Crescimento Endotelial Vascular (VEGFR) são compostos que bloqueiam a sinalização do VEGFR, um receptor chave na via VEGF, crucial para a angiogênese. Os inibidores de VEGFR impedem a formação de novos vasos sanguíneos que fornecem nutrientes e oxigênio aos tumores, inibindo assim o crescimento tumoral. Esses inibidores são amplamente utilizados na terapia contra o câncer e na pesquisa para estudar os mecanismos da angiogênese e desenvolver tratamentos anticâncer. Na CymitQuimica, oferecemos uma ampla gama de inibidores de VEGFR de alta qualidade para apoiar sua pesquisa em oncologia, biologia vascular e angiogênese.
Foram encontrados 239 produtos de "VEGFR"
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NVP-BAW2881
CAS:NVP-BAW2881 (BAW2881) is a potent and selective VEGFR inhibitor with activity to inhibit chronic and acute skin inflammation.Fórmula:C22H15F3N4O2Pureza:98.19% - 99.97%Cor e Forma:SolidPeso molecular:424.38Ref: TM-T3641
1mg34,00€2mg48,00€5mg71,00€10mg109,00€25mg200,00€50mg324,00€100mg470,00€500mg1.054,00€1mL*10mM (DMSO)69,00€SU5205
CAS:SU5205 is a VEGFR2 inhibitor.
Fórmula:C15H10FNOPureza:99.62% - 99.67%Cor e Forma:SolidPeso molecular:239.24Foretinib
CAS:Foretinib (GSK1363089) is a broad-spectrum tyrosine kinase inhibitor with IC50s of 0.4 nM and 0.9 nM for Met and KDR.Fórmula:C34H34F2N4O6Pureza:98.07% - 99.68%Cor e Forma:SolidPeso molecular:632.65Ref: TM-T3113
2mg39,00€5mg57,00€10mg79,00€25mg133,00€50mg207,00€100mg354,00€500mg848,00€1mL*10mM (DMSO)79,00€Vorolanib
CAS:Vorolanib (X-82) is an orally active VEGFR/PDGFR dual inhibitor.Fórmula:C23H26FN5O3Pureza:97.35%Cor e Forma:SolidPeso molecular:439.48Ref: TM-T8491
1mg101,00€2mg142,00€5mg215,00€10mg340,00€25mg583,00€50mg842,00€100mg1.144,00€200mg1.521,00€1mL*10mM (DMSO)236,00€Fruquintinib
CAS:Fruquintinib (HMPL-013) is an orally available, small molecule inhibitor of vascular endothelial growth factor receptors (VEGFRs), with potential anti-Fórmula:C21H19N3O5Pureza:98.84% - 99.89%Cor e Forma:SolidPeso molecular:393.39Ref: TM-T2656
2mg35,00€5mg52,00€10mg85,00€25mg117,00€50mg147,00€100mg250,00€500mg620,00€1mL*10mM (DMSO)58,00€Orantinib
CAS:Orantinib (NSC 702827) , a excellent effective against PDGFR autophosphorylation with Ki of 8 nM, also highly inhibits Flk-1 and FGFR1 trans-phosphorylation.Fórmula:C18H18N2O3Pureza:98.92% - 99.52%Cor e Forma:SolidPeso molecular:310.35AG-13958
CAS:AG-13958 (AG-013958) (AG-013958), a potent VEGFR tyrosine kinase inhibitor, for the treatment of age-related macular degeneration.Fórmula:C26H22FN7OPureza:99.4%Cor e Forma:SolidPeso molecular:467.5Ref: TM-T7493
1mg92,00€5mg250,00€10mg385,00€25mg620,00€50mg893,00€100mg1.189,00€1mL*10mM (DMSO)260,00€Motesanib
CAS:Motesanib (AMG 706) orally blocks VEGFR, PDGFR, Kit, Ret; curbing angiogenesis and cancer cell growth.Fórmula:C22H23N5OPureza:98% - 99.09%Cor e Forma:SolidPeso molecular:373.45Ref: TM-T2288
5mg34,00€10mg49,00€25mg81,00€50mg114,00€100mg160,00€200mg230,00€500mg389,00€1mL*10mM (DMSO)39,00€KRN-633
CAS:KRN-633 is an effective VEGFR inhibitor. The IC50s of KRN-633(KRN633) for VEGFR1, VEGFR2, and VEGFR3 is 170, 160 and 125 nM, respectively.Fórmula:C20H21ClN4O4Pureza:99.53% - 99.73%Cor e Forma:SolidPeso molecular:416.86JI-101
CAS:JI-101 (CGI-1842) is an oral multi-kinase inhibitor that targets VEGFR-2, PDGFR-β, and EphB4.Fórmula:C22H20BrN5O2Pureza:99.41% - 99.97%Cor e Forma:SolidPeso molecular:466.33Ilorasertib
CAS:Ilorasertib (ABT-348) inhibits Aurora kinases A/B/C & RET, PDGFRβ, Flt1 (IC50: 1-120 nM).Fórmula:C25H21FN6O2SPureza:96.17% - 97.49%Cor e Forma:SolidPeso molecular:488.54Cediranib
CAS:Cediranib (AZD2171) is a potent KDR tyrosine kinase inhibitor (IC50 < 1nM), also targets Flt1/4, PDGFRβ, c-Kit, and more selective for VEGFR.Fórmula:C25H27FN4O3Pureza:97.21% - 99.94%Cor e Forma:SolidPeso molecular:450.51Ref: TM-T2500
2mg42,00€5mg63,00€10mg92,00€25mg136,00€50mg177,00€100mg254,00€200mg462,00€500mg742,00€1mL*10mM (DMSO)69,00€SCR-1481B1
CAS:SCR-1481B1 (c-Met inhibitor 2) has activity against cancers dependent on Met activation and also has activity against cancers as a VEGFR inhibitorFórmula:C32H40ClF2N6O13PPureza:98.07%Cor e Forma:SolidPeso molecular:821.12Ref: TM-T5349
1mg35,00€2mg50,00€5mg74,00€10mg113,00€25mg200,00€50mg333,00€100mg495,00€1mL*10mM (DMSO)102,00€Oglufanide
CAS:Oglufanide (H-Glu-Trp-OH) is a naturally occurring thymic immunomodulator,and inhibits vascular endothelial growth factor (VEGF).Fórmula:C16H19N3O5Pureza:99.80%Cor e Forma:SolidPeso molecular:333.34EOC317
CAS:EOC317 (ACTB-1003) is an oral kinase inhibitor (IC50: 6/2/4 nM, for FGFR1/VEGFR2/Tie-2).Fórmula:C27H26F5N7O3Pureza:98.00% - 99.26%Cor e Forma:SolidPeso molecular:591.53SU5208
CAS:SU5208 (3-[(Thien-2-yl)methylene]-2-indolinone) is a compound with bioactivity.SU5208 inhibits vascular endothelial growth factor receptor-2 (VEGFR2).Fórmula:C13H9NOSPureza:99.62%Cor e Forma:SolidPeso molecular:227.28Ref: TM-T22432
1mg46,00€5mg94,00€10mg148,00€25mg225,00€50mg310,00€100mg434,00€200mg583,00€1mL*10mM (DMSO)95,00€Linifanib
CAS:Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) andFórmula:C21H18FN5OPureza:98% - 98.24%Cor e Forma:SolidPeso molecular:375.4Ref: TM-T2514
5mg48,00€10mg80,00€25mg119,00€50mg178,00€100mg259,00€200mg477,00€500mg772,00€1mL*10mM (DMSO)50,00€GW786034B
CAS:Pazopanib HCl (Votrient) inhibits VEGFR1-3, PDGFR, FGFR, c-Kit, c-Fms with IC50 range 10-146 nM in cell-free assays.Fórmula:C21H23N7O2S·HClPureza:99.87%Cor e Forma:SolidPeso molecular:473.98Ref: TM-T6930
10mg44,00€25mg70,00€50mg96,00€100mg140,00€200mg229,00€500mg329,00€1mL*10mM (DMSO)34,00€KI8751
CAS:KI8751 is a potent and selective inhibitor of VEGFR2 with IC50 of 0.9 nM.Fórmula:C24H18F3N3O4Pureza:99.22% - 99.9%Cor e Forma:SolidPeso molecular:469.41Ref: TM-T2446
2mg37,00€5mg52,00€10mg86,00€25mg156,00€50mg294,00€100mg472,00€200mg670,00€1mL*10mM (DMSO)56,00€Vatalanib dihydrochloride
CAS:Vatalanib dihydrochloride (PTK787 dihydrochloride)(IC50=37 nM) is an inhibitor of VEGFR2/KDR.Fórmula:C20H15ClN4·2HClPureza:99.16%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:419.73
