VEGFR
Os inibidores do Receptor do Fator de Crescimento Endotelial Vascular (VEGFR) são compostos que bloqueiam a sinalização do VEGFR, um receptor chave na via VEGF, crucial para a angiogênese. Os inibidores de VEGFR impedem a formação de novos vasos sanguíneos que fornecem nutrientes e oxigênio aos tumores, inibindo assim o crescimento tumoral. Esses inibidores são amplamente utilizados na terapia contra o câncer e na pesquisa para estudar os mecanismos da angiogênese e desenvolver tratamentos anticâncer. Na CymitQuimica, oferecemos uma ampla gama de inibidores de VEGFR de alta qualidade para apoiar sua pesquisa em oncologia, biologia vascular e angiogênese.
Foram encontrados 239 produtos de "VEGFR"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
R1530
CAS:R1530 is a multikinase inhibitor with antineoplastic and antiangiogenesis activities.Fórmula:C18H14ClFN4OPureza:98.422%Cor e Forma:SolidPeso molecular:356.78Ref: TM-TQ0317
1mg39,00€2mg52,00€5mg84,00€10mg130,00€25mg264,00€50mg423,00€100mg640,00€1mL*10mM (DMSO)93,00€SAR131675
CAS:SAR131675 is a potent and selective VEGFR3 inhibitor with an IC50 of 23 nM.Fórmula:C18H22N4O4Pureza:99.74%Cor e Forma:SolidPeso molecular:358.39Ref: TM-T6012
1mg34,00€2mg46,00€5mg70,00€10mg105,00€25mg215,00€50mg304,00€100mg427,00€200mg587,00€1mL*10mM (DMSO)79,00€Nintedanib esylate
CAS:Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/βFórmula:C31H33N5O4·C2H6O3SPureza:99.43% - 99.98%Cor e Forma:SolidPeso molecular:649.76Ki20227
CAS:Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM).Fórmula:C24H24N4O5SPureza:98.97% - 99.88%Cor e Forma:SolidPeso molecular:480.54Ref: TM-T4315
1mg44,00€5mg90,00€10mg145,00€25mg268,00€50mg439,00€100mg700,00€200mg954,00€1mL*10mM (DMSO)90,00€Tyrphostin A9
CAS:Tyrphostin A9 (SF 6847) is an Agricultural acaricide, now superseded. Tyrphostin A9 is firstly designed as an EGFR inhibitorFórmula:C18H22N2OPureza:98.21% - 99.87%Cor e Forma:Yellow SolidPeso molecular:282.38Telatinib
CAS:Telatinib (Bay 57-9352) inhibits VEGFR2/3, c-Kit, PDGFRα with IC50s: 6 nM, 4 nM, 1 nM, 15 nM.Fórmula:C20H16ClN5O3Pureza:97.61% - 99.81%Cor e Forma:SolidPeso molecular:409.83Altiratinib
CAS:Altiratinib (DCC-2701)(DCC-2701) is a novel c-MET/TIE-2/VEGFR inhibitor; effectively reduce tumor burden in vivo and block c-MET pTyr(1349)-mediated signaling,Fórmula:C26H21F3N4O4Pureza:99.67% - 99.75%Cor e Forma:SolidPeso molecular:510.46Gamabufotalin
CAS:Gamabufotalin, a Chansu bufadienolide, treats COX-2 diseases and cancer with high stability and low side effects.Fórmula:C24H34O5Pureza:99.18% - 99.51%Cor e Forma:SolidPeso molecular:402.52WHI-P180
CAS:WHI-P180 (Janex 3) is a potent EGFR and Cdk2 inhibitors with IC50 of 4.0 and 1.0 uM, respectively.Fórmula:C16H15N3O3Pureza:99.21%Cor e Forma:SolidPeso molecular:297.31SU 5402
CAS:SU 5402 is a potent multi-targeted receptor tyrosine kinase inhibitor with IC50 of 20 nM, 30 nM, and 510 nM for VEGFR2, FGFR1, and PDGF-Rβ, respectively.Fórmula:C17H16N2O3Pureza:98.91% - 99.64%Cor e Forma:Yellow-Green SolidPeso molecular:296.32SKLB 610
CAS:SKLB610, a novel multi-targeted inhibitor, inhibits angiogenesis-related tyrosine kinase VEGFR2, FGFR2, and PDGFR at a rate of 97%, 65%, and 55%, respectively,
Fórmula:C21H16F3N3O3Pureza:99.33% - 99.83%Cor e Forma:SolidPeso molecular:415.37SU5204
CAS:SU5204 (3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one), an analogue of SU5025, pharmacologically inhibits VEGFR2(IC50s of 4 and 51.5 μM for FLK-1 (VEGFR-2) andFórmula:C17H15NO2Pureza:99.46%Cor e Forma:SolidPeso molecular:265.31Tivozanib
CAS:Tivozanib (KRN951) is an oral VEGFRs 1-3 inhibitor with potential antiangiogenic and cancer-fighting properties.Fórmula:C22H19ClN4O5Pureza:98.08% - 99.67%Cor e Forma:SolidPeso molecular:454.86Ref: TM-T2456
2mg38,00€5mg57,00€10mg79,00€25mg135,00€50mg226,00€100mg405,00€200mg597,00€1mL*10mM (DMSO)63,00€MAZ51
CAS:MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.Fórmula:C21H18N2OPureza:98.53%Cor e Forma:SolidPeso molecular:314.38AZD2932
CAS:AZD2932 is a potent and multi-targeted kinase inhibitor VEGFR2, PDGFβ, Flt-3, and c-Kit.Fórmula:C24H25N5O4Pureza:97.71% - 98.37%Cor e Forma:SolidPeso molecular:447.49AMG-47a
CAS:AMG-47a inhibits Lck, T cell growth, and degrades KRAS oncoprotein, affecting EGFP-KRASG12V but not EGFP.Fórmula:C29H28F3N5O2Pureza:98%Cor e Forma:SolidPeso molecular:535.56Xanthatin
CAS:Xanthatin exhibits cytotoxic, antibacterial, antifungal properties, may treat NSCLC, and inhibits melanoma by targeting Wnt/β-catenin and angiogenesis.Fórmula:C15H18O3Pureza:98.48% - 99.96%Cor e Forma:SolidPeso molecular:246.3Dovitinib lactate
CAS:Dovitinib lactate (TKI-258 lactate)(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).Fórmula:C24H27FN6O4Pureza:99.54% - 99.77%Cor e Forma:SolidPeso molecular:482.51Ref: TM-T7104
5mg51,00€10mg79,00€25mg129,00€50mg213,00€100mg358,00€200mg535,00€500mg843,00€1mL*10mM (DMSO)57,00€AAL-993
CAS:AAL-993: VEGFR inhibitor; IC50: 130 nM (1), 23 nM (2), 18 nM (3); weak on other tyrosine kinases; antiangiogenic & antitumor.Fórmula:C20H16F3N3OPureza:99.65%Cor e Forma:SolidPeso molecular:371.36Ref: TM-T21593
1mg43,00€5mg93,00€10mg138,00€25mg260,00€50mg409,00€100mg605,00€500mg1.288,00€1mL*10mM (DMSO)92,00€RAF265
CAS:RAF265 (CHIR-265) inhibits C-Raf/B-Raf/V600E (IC50: 3-60 nM), blocks VEGFR2 (EC50: 30 nM), in Phase 2 trials.Fórmula:C24H16F6N6OPureza:99.56%Cor e Forma:SolidPeso molecular:518.41Ref: TM-T6296
1mg44,00€2mg59,00€5mg93,00€10mg140,00€25mg253,00€50mg413,00€100mg605,00€1mL*10mM (DMSO)94,00€
