PDGFR
Os inibidores do receptor do fator de crescimento derivado de plaquetas (PDGFR) são compostos que bloqueiam a sinalização do PDGFR, um receptor envolvido no crescimento celular, proliferação e angiogênese. O PDGFR desempenha um papel significativo no desenvolvimento dos vasos sanguíneos que alimentam os tumores. Inibir o PDGFR pode, portanto, impedir a angiogênese, tornando esses inibidores valiosos na terapia contra o câncer. Na CymitQuimica, oferecemos uma seleção de inibidores de PDGFR de alta qualidade para apoiar sua pesquisa em oncologia, biologia vascular e angiogênese.
Foram encontrados 130 produtos para "PDGFR".
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Dasatinib
CAS:Fórmula:C22H26ClN7O2SPureza:>95.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:488.01Imatinib
CAS:Fórmula:C29H31N7OPureza:>98.0%(HPLC)Cor e Forma:White to Light yellow to Light orange powder to crystalPeso molecular:493.62TCS 359
CAS:Fórmula:C18H20N2O4SPureza:>98.0%(HPLC)Cor e Forma:Light yellow to Brown powder to crystalPeso molecular:360.43Axitinib
CAS:Axitinib (AG-013736) is a multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1/2/3 and PDGFRβ. Axitinib has antitumor activity. Cost-effective and quality-assured.Fórmula:C22H18N4OSPureza:98.9% - 99.74%Cor e Forma:Off-White SolidPeso molecular:386.47Olaratumab
CAS:Olaratumab(IMC-3G3) is a human monoclonal IgG1 antibody against platelet-derived growth factor receptor alpha (PDGFRα), which has antitumor effects and can bePureza:SDS-PAGE:95% SEC-HPLC:98.70%Cor e Forma:Transparent LiquidPeso molecular:147.12 kDaPazopanib
CAS:Pazopanib (GW786034) is an inhibitor of protein tyrosine kinases that inhibits VEGFR1/2/3. Pazopanib has antitumor activity. Cost-effective and quality-assured.Fórmula:C21H23N7O2SPureza:98.78% - 99.85%Cor e Forma:SolidPeso molecular:437.52AG 1295
CAS:AG 1295 is a selective PDGFR tyrosine-kinase inhibitor; it blocks PDGFR autophosphorylation without affecting EGF receptor.Fórmula:C16H14N2Pureza:99.93%Cor e Forma:SolidPeso molecular:234.34-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide
CAS:Fórmula:C29H31N7OPureza:98%Cor e Forma:SolidPeso molecular:493.6027Imatinib Mesylate
CAS:Imatinib Mesylate (STI-571) is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, 0.1 μM and 0.1 μM for v-Abl, c-Kit and PDGFR,Fórmula:C29H31N7O·CH4SO3Pureza:98% - >99.99%Cor e Forma:White SolidPeso molecular:589.71Regorafénib N-oxyde (M2)
CAS:Regorafénib N-oxyde M2 is an active metabolite of Regorafenib.Fórmula:C21H15ClF4N4O4Pureza:98.03% - 98.26%Cor e Forma:White SolidPeso molecular:498.812-(3,4-Dimethoxyphenylcarbamoyl)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide
CAS:Fórmula:C18H20N2O4SPureza:%Cor e Forma:SolidPeso molecular:360.4274Sunitinib Malate
CAS:Sunitinib Malate (Sunitinib) is an indolinone-based tyrosine kinase inhibitor.Fórmula:C26H33FN4O7Pureza:98% - 99.26%Cor e Forma:SolidPeso molecular:532.56Lenvatinib
CAS:Lenvatinib (E7080) is a multi-target receptor tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, KIT, PDGFR, and RET, and has oral activity.Fórmula:C21H19ClN4O4Pureza:98.46% - 99.96%Cor e Forma:White SolidPeso molecular:426.85Trapidil
CAS:Trapidil (Avantrin) is a coronary vasodilator agent.Fórmula:C10H15N5Pureza:99.42%Cor e Forma:White SolidPeso molecular:205.26JNJ-10198409
CAS:JNJ-10198409: selective ATP competitive PDGF-RTK inhibitor; IC50: PDGFR-β 4.2 nM, PDGFR-α 45 nM; antiangiogenic & antiproliferative.Fórmula:C18H16FN3O2Pureza:98.51%Cor e Forma:Yellow SolidPeso molecular:325.34Ref: TM-T15616
1mg33,00€5mg92,00€1mL*10mM (DMSO)92,00€10mg122,00€25mg198,00€50mg294,00€100mg419,00€200mg587,00€Sunitinib
CAS:Sunitinib (SU 11248) is a multi-targeted receptor tyrosine kinase (RTK) inhibitor that inhibits VEGFR2 and PDGFRβ (IC50=80/2 nM).Fórmula:C22H27FN4O2Pureza:98% - 99.67%Cor e Forma:Yellow SolidPeso molecular:398.47N-Desmethyl imatinib
CAS:N-Desmethyl imatinib (Imatinib metabolite N-Desmethyl imatinib) is a metabolite of Imatinib, which is a multi-target inhibitor of c-Kit, v-Abl, and PDGFR.Fórmula:C28H29N7OPureza:98.60%Cor e Forma:SolidPeso molecular:479.58Ref: TM-T11641
1mg87,00€5mg166,00€1mL*10mM (DMSO)170,00€10mg303,00€25mg512,00€50mg737,00€100mg1.018,00€2-Pyridinecarboxamide,4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluorophenoxy]-N-methyl-
CAS:Fórmula:C21H15ClF4N4O3Pureza:98%Cor e Forma:SolidPeso molecular:482.8154Ref: IN-DA00ICN3
100gA consultar10mg30,00€50mg46,00€100mg56,00€250mg69,00€500mg100,00€1g131,00€5g255,00€50g617,00€10g619,00€
![4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benz…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb-webp%2FDA00350H.webp&w=3840&q=75)
![2-Pyridinecarboxamide,4-[4-[[[[4-chloro-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]-3-fluoroph…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb-webp%2FDA00ICN3.webp&w=3840&q=75)