FLT
Os inibidores de FLT (Fms-like tyrosine kinase) são compostos que têm como alvo os receptores FLT, que estão envolvidos na regulação da angiogênese através da via do VEGF (fator de crescimento endotelial vascular). Os receptores FLT desempenham um papel crucial no desenvolvimento de novos vasos sanguíneos em tumores. Inibir os receptores FLT pode reduzir efetivamente a angiogênese e o crescimento tumoral, tornando esses inibidores importantes na terapia contra o câncer. Na CymitQuimica, oferecemos uma seleção de inibidores de FLT de alta qualidade para apoiar sua pesquisa em oncologia, biologia vascular e angiogênese.
Foram encontrados 86 produtos para "FLT".
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FLT3 Ligand-Linker Conjugate 1
CAS:FLT3 Ligand-Linker Conjugate 1 consists of an FLT3 ligand and a PROTAC linker that can recruit E3 ligase VHL. This conjugate is useful for synthesizing PROTAC RSS0680, a bifunctional compound designed for targeted protein degradation of kinases.Fórmula:C29H34N6O4S2Cor e Forma:SolidPeso molecular:594.748FLT3-IN-16
CAS:FLT3-IN-16 is a potent FLT3 inhibitor (IC50 = 1.1 μM) for acute myeloid leukemia research.Fórmula:C15H15N3O2SPureza:99.21%Cor e Forma:SolidPeso molecular:301.36VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi), Biotinylated
VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag.Cor e Forma:Lyophilized PowderPeso molecular:85.1 kDa (predicted). Due to glycosylation, the protein migrates to 100-120 kDa based on Tris-Bis PAGE result.Ref: TM-TMPK-00451
5µg94,00€10µg138,00€20µg220,00€50µg434,00€100µg732,00€200µg1.324,00€500µg2.925,00€JNJ-47117096 hydrochloride
CAS:JNJ-47117096 hydrochloride is potent and selective MELK inhibitor, with an IC50 of 23 nM, also effectively inhibits Flt3, with an IC50 of 19 nM.Fórmula:C21H23ClN4O2Pureza:99.76%Cor e Forma:SolidPeso molecular:398.89BPR1K871
CAS:BPR1K871, a preclinical development candidate for anti-cancer therapy [1], is a potent, selective dual inhibitor targeting FLT3 and AURKA, with IC50 values ofFórmula:C25H28ClN7O2SCor e Forma:SolidPeso molecular:526.05Anti-FLT1 Antibody (6K171)
Anti-FLT1 Antibody (6K171) is a Mouse antibody targeting FLT1. Anti-FLT1 Antibody (6K171) can be used in ELISA,ICC/IF.Cor e Forma:Odour LiquidFLT1 Protein, Human, Recombinant (His & Avi), Biotinylated
FLT1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag.Cor e Forma:Lyophilized PowderPeso molecular:85.45 kDa (predicted); 113.32 kDa (reducing conditions)Anti-FLT1 Antibody (3W705)
Anti-FLT1 Antibody (3W705) is an antibody targeting FLT1. Anti-FLT1 Antibody (3W705) can be used in ELISA, WB, IHC, FCM.Cor e Forma:Odour LiquidAnti-VEGFR1/FLT-1 Antibody (9F18)
Anti-VEGFR1/FLT-1 Antibody (9F18) is a Rabbit antibody targeting VEGFR1/FLT-1. Anti-VEGFR1/FLT-1 Antibody (9F18) can be used in ELISA.Cor e Forma:Odour LiquidFLT1 Protein, Human, Recombinant (hFc)
FLT1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Cor e Forma:Lyophilized PowderPeso molecular:61.1 kDa (predicted)Ref: TM-TMPY-00119
5µg79,00€10µg110,00€20µg177,00€50µg359,00€100µg615,00€200µg1.080,00€500µg2.692,00€VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi)
VEGFR1/FLT-1 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag.Cor e Forma:Lyophilized PowderPeso molecular:85.1 kDa (predicted). Due to glycosylation, the protein migrates to 100-120 kDa based on Tris-Bis PAGE result.FLT1 Protein, Human, Recombinant (aa 1-328, His)
FLT1 Protein, Human, Recombinant (aa 1-328, His) is expressed in HEK293 mammalian cells with His tag.Pureza:97.5%Cor e Forma:White Lyophilized PowderPeso molecular:35.6 kDa (predicted)FLT1 Protein, Human, Recombinant (aa 1-756, His)
FLT1 Protein, Human, Recombinant (aa 1-756, His) is expressed in HEK293 mammalian cells with His tag.Cor e Forma:Lyophilized PowderPeso molecular:83.7 kDa (predicted); 110-120 kDa (reducing condition, due to glycosylation)Ref: TM-TMPY-02108
5µg60,00€10µg96,00€20µg141,00€50µg269,00€100µg520,00€200µg777,00€500µg1.549,00€1mg3.177,00€Pacritinib
CAS:Pacritinib (SB1518) (SB1518) is an effective and specific inhibitor of JAK2 and FLT3 (IC50: 23/22 nM, in cell-free assays).Fórmula:C28H32N4O3Pureza:99.25% - 99.49%Cor e Forma:SolidPeso molecular:472.58TCS 359
CAS:TCS 359 (FLT3 Inhibitor) is a potent FLT3 inhibitor with IC50 of 42 nM.Fórmula:C18H20N2O4SPureza:99.31%Cor e Forma:SolidPeso molecular:360.427FLT3-IN-2
CAS:FLT3-IN-2 is an FLT3 inhibitor (IC50<1 μM).Fórmula:C21H16ClF3N4Pureza:97.57% - 98.53%Cor e Forma:SolidPeso molecular:416.83UNC2025 2HCl
UNC2025 is a potent and orally bioavailable Mer/Flt3 dual inhibitor with IC50 of 0.8/0.74 nM for Mer/Flt3.Fórmula:C28H42Cl2N6OPureza:99.71%Cor e Forma:SolidPeso molecular:549.62Ref: TM-T4419
1mg52,00€2mg77,00€5mg95,00€10mg163,00€1mL*10mM (DMSO)163,00€25mg306,00€50mg538,00€100mg767,00€5'-Fluoroindirubinoxime
CAS:5'-Fluoroindirubinoxime (5'-FIO) is a potent FLT3 inhibitor( IC50 : 15 nM).Fórmula:C16H10FN3O2Pureza:>99.99%Cor e Forma:SolidPeso molecular:295.27INE963
CAS:INE963: Potent against Pf 3D7 (EC50=6nM), clears parasites in <24h; effective on P. falciparum/vivax isolates (EC50=0.01-7nM).Fórmula:C19H26N6O2SPureza:99.08% - 99.45%Cor e Forma:SolidPeso molecular:402.51BPR1J-097 hydrochloride
BPR1J-097, a new-type small molecule FLT-3 inhibitor(IC50=11±7 nM), is with great anti-tumor activities in vivo.Fórmula:C27H29ClN6O3SPureza:98% - 98.54%Cor e Forma:SolidPeso molecular:553.07Ref: TM-T4261
1mg48,00€2mg63,00€5mg89,00€1mL*10mM (DMSO)140,00€10mg146,00€25mg256,00€50mg434,00€100mg620,00€
