FLT
Os inibidores de FLT (Fms-like tyrosine kinase) são compostos que têm como alvo os receptores FLT, que estão envolvidos na regulação da angiogênese através da via do VEGF (fator de crescimento endotelial vascular). Os receptores FLT desempenham um papel crucial no desenvolvimento de novos vasos sanguíneos em tumores. Inibir os receptores FLT pode reduzir efetivamente a angiogênese e o crescimento tumoral, tornando esses inibidores importantes na terapia contra o câncer. Na CymitQuimica, oferecemos uma seleção de inibidores de FLT de alta qualidade para apoiar sua pesquisa em oncologia, biologia vascular e angiogênese.
Foram encontrados 86 produtos para "FLT".
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HPK1-IN-2
CAS:HPK1-IN-2 is a strong, oral HPK1 inhibitor (IC50<0.05 μM), also blocking Lck, Flt3 kinases, with anticancer properties.Fórmula:C19H20N6OSPureza:97.31%Cor e Forma:SolidPeso molecular:380.47Ref: TM-T9017
1mg73,00€5mg136,00€1mL*10mM (DMSO)161,00€10mg219,00€25mg365,00€50mg520,00€100mg692,00€200mg888,00€FLT3-IN-2
CAS:FLT3-IN-2 is an FLT3 inhibitor (IC50<1 μM).Fórmula:C21H16ClF3N4Pureza:97.57% - 98.53%Cor e Forma:SolidPeso molecular:416.83Ref: TM-T1938
1mg40,00€2mg52,00€5mg82,00€1mL*10mM (DMSO)93,00€10mg113,00€25mg200,00€50mg333,00€100mg477,00€UNC2025
CAS:UNC2025 (mrx-6313)(IC50 of 0.74 nM and 0.8 nM) is a potent and orally bioavailable dual MER/FLT3 inhibitor.Fórmula:C28H40N6OPureza:99.53% - 99.74%Cor e Forma:Yellow SolidPeso molecular:476.66UNC2541
CAS:UNC2541 is a potent and Mer tyrosine kinase (MerTK)-specific inhibitor.Fórmula:C24H34FN7O2Pureza:98.33%Cor e Forma:White SolidPeso molecular:471.57BPR1J-097 hydrochloride (1327167-19-0(free base))
BPR1J-097, a new-type small molecule FLT-3 inhibitor(IC50=11±7 nM), is with great anti-tumor activities in vivo.Fórmula:C27H29ClN6O3SPureza:98% - 98.54%Cor e Forma:SolidPeso molecular:553.07Ref: TM-T4261
1mg48,00€2mg63,00€5mg89,00€1mL*10mM (DMSO)140,00€10mg146,00€25mg256,00€50mg434,00€100mg620,00€4SC-203
CAS:4SC-203 is a multi-kinase inhibitor with potential anti-tumor activity.Cost-effective and quality-assured.Fórmula:C33H38N8O4SPureza:99.52% - 99.98%Cor e Forma:SolidPeso molecular:642.77TAK-659 hydrochloride
CAS:TAK-659 hydrochloride (TAK-659) is a potent and selective inhibitor of spleen tyrosine kinase (SYK) with an IC50 value of 3.2 nM.Fórmula:C17H22ClFN6OPureza:99.28% - 99.82%Cor e Forma:SolidPeso molecular:380.85UNC2025 2HCl (1429881-91-3(free base))
UNC2025 is a potent and orally bioavailable Mer/Flt3 dual inhibitor with IC50 of 0.8/0.74 nM for Mer/Flt3.Fórmula:C28H42Cl2N6OPureza:99.71%Cor e Forma:SolidPeso molecular:549.62Ref: TM-T4419
1mg52,00€2mg77,00€5mg95,00€10mg163,00€1mL*10mM (DMSO)163,00€25mg306,00€50mg538,00€100mg767,00€Gilteritinib hemifumarate
CAS:Gilteritinib hemifumarate (ASP2215 hemifumarate) is a potent ATP-competitive dual FLT3 (IC50: 0.29 nM) and AXL (IC50: 0.73 nM) inhibitor for the treatment ofFórmula:C29H44N8O3C4H4O4Pureza:99.78%Cor e Forma:SolidPeso molecular:610.75FLT3/ITD-IN-2
CAS:FLT3/ITD-IN-2: Powerful FLT3/ITD, FLT3D835Y, and FLT3 inhibitor; hinders AML cell growth. IC50s: 0.3-1.0 nM.Fórmula:C23H26F3N7O2Cor e Forma:SolidPeso molecular:489.49PDGFRα/FLT3-ITD-IN-3
CAS:PDGFRα/FLT3-ITD-IN-3 (Compound 18d) is a potent inhibitor of PDGFRα (IC50: 0.153 μM), FLT3 (IC50: 0.004 μM) and PDGFRα/FLT3-ITD-IN-3 has the potential to beFórmula:C26H39N9Cor e Forma:SolidPeso molecular:477.65PDGFRα/FLT3-ITD-IN-2
CAS:PDGFRα/FLT3-ITD-IN-2 is a potent inhibitor of PDGFRα (IC50>20 μM) and FLT3 (IC50: 0.004 μM).Fórmula:C28H41N9OCor e Forma:SolidPeso molecular:519.68FLT3-IN-18
CAS:FLT3-IN-18: potent, selective FLT3 inhibitor, IC50 0.003 μM, induces apoptosis, G1 arrest, blocks FLT3/STAT5, potential in AML research.Fórmula:C26H36N8OCor e Forma:SolidPeso molecular:476.62FLT3/D835Y-IN-1
CAS:FLT3/D835Y-IN-1, an oral FLT3 inhibitor (IC50: FLT3 - 0.26 nM, D835Y - 0.18 nM), shows anticancer potential in AML research.Fórmula:C22H21N5O3Cor e Forma:SolidPeso molecular:403.43AGL 2043
CAS:AGL 2043 is a potent, reversible, ATP-competitive inhibitor of type III receptor tyrosine kinases.Fórmula:C15H12N4SCor e Forma:SolidPeso molecular:280.35MDK5466
CAS:MDK5466 is an Flt3 inhibitor that acts by preventing glutamate-induced cell death.Fórmula:C21H23N3OSPureza:98%Cor e Forma:SolidPeso molecular:365.49PDGFRα/FLT3-ITD-IN-1
CAS:PDGFRα/FLT3-ITD-IN-1 are potent inhibitors of PDGFRα/FLT3, and their IC50 values are greater than 0.036 and 0.003 μM, respectively.Fórmula:C27H39N9OCor e Forma:SolidPeso molecular:505.66BSc5371
CAS:BSc5371: Irreversible FLT3 inhibitor; Kds 0.83-5.8 nM for various FLT3 mutants including wild type.Fórmula:C24H31N5O4SPureza:98%Cor e Forma:SolidPeso molecular:485.6FLT3-IN-11
CAS:FLT3-IN-11, an oral FLT3 kinase inhibitor: potent, selective, IC50 - wild-type 7.22 nM, FLT3-D835Y 4.95 nM, anti-AML IC50 3.2 nM for MV4-11.Fórmula:C20H25F3N6OCor e Forma:SolidPeso molecular:422.45HP1328
CAS:HP1328: potent FLT3/ITD inhibitor, reduces leukemia, extends survival in mice, belongs to benzoimidazole family.Fórmula:C23H23N3O3Cor e Forma:SolidPeso molecular:389.45
