c-Kit
Os inibidores de c-Kit são compostos que bloqueiam a atividade do Receptor do Fator de Células-Tronco (c-Kit), uma tirosina quinase que desempenha um papel crucial na sobrevivência, proliferação e diferenciação celular, particularmente em células hematopoéticas. As mutações em c-Kit estão ligadas a vários tipos de câncer, incluindo tumores estromais gastrointestinais (GIST) e leucemia. Na CymitQuimica, oferecemos inibidores de c-Kit para apoiar sua pesquisa em oncologia, hematologia e biologia de células-tronco.
Foram encontrados 118 produtos para "c-Kit".
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Pazopanib
CAS:Pazopanib (GW786034) is an inhibitor of protein tyrosine kinases that inhibits VEGFR1/2/3. Pazopanib has antitumor activity. Cost-effective and quality-assured.Fórmula:C21H23N7O2SPureza:98.78% - 99.85%Cor e Forma:SolidPeso molecular:437.518JI6
CAS:JI6 (JAK3 Inhibitor VI) is a potent, selective and orally active FLT3 inhibitor.Fórmula:C19H17N3O4SPureza:99.09%Cor e Forma:SoildPeso molecular:383.421Imatinib Mesylate
CAS:Imatinib Mesylate (STI-571) is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, 0.1 μM and 0.1 μM for v-Abl, c-Kit and PDGFR,Fórmula:C29H31N7O·CH4SO3Pureza:98% - >99.99%Cor e Forma:White SolidPeso molecular:589.71N-Desmethyl imatinib
CAS:N-Desmethyl imatinib (Imatinib metabolite N-Desmethyl imatinib) is a metabolite of Imatinib, which is a multi-target inhibitor of c-Kit, v-Abl, and PDGFR.Fórmula:C28H29N7OPureza:98.60%Cor e Forma:SolidPeso molecular:479.5762Lenvatinib
CAS:Lenvatinib (E7080) is a multi-target receptor tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, KIT, PDGFR, and RET, and has oral activity.Fórmula:C21H19ClN4O4Pureza:98.46% - 99.96%Cor e Forma:White SolidPeso molecular:426.85Regorafénib N-oxyde (M2)
CAS:Regorafénib N-oxyde M2 is an active metabolite of Regorafenib.Fórmula:C21H15ClF4N4O4Pureza:98.03% - 98.26%Cor e Forma:White SolidPeso molecular:498.815Axitinib
CAS:Axitinib (AG-013736) is a multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1/2/3 and PDGFRβ. Axitinib has antitumor activity. Cost-effective and quality-assured.Fórmula:C22H18N4OSPureza:98.9% - 99.74%Cor e Forma:Off-White SolidPeso molecular:386.47KG5
CAS:KG5 inhibits PDGFRβ, B-Raf, FLT3, KIT, c-Raf; has anticancer and antiangiogenic effects; Kd: 520 nM (PDGFRβ), 300 nM (PDGFRα).Fórmula:C20H16F3N7OSPureza:98.32%Cor e Forma:SolidPeso molecular:459.45Anti-Human c-Kit Antibody (LMJ729)
Anti-c-Kit Antibody (LMJ729) is a human antibody, which is used in targeted delivery research.Pureza:97.0% (SDS-PAGE); 95.8% (SEC-HPLC) - 97.0% (SDS-PAGE); 95.8% (SEC-HPLC)Peso molecular:145.93 kDa (Predicted)AK177
AK177 is an allosteric activator of IRE1α ribonuclease, exhibiting binding affinities of 480 nM for non-phosphorylated and 180 nM for phosphorylated IRE1α. It promotes concentration-dependent cleavage of XBP1 mRNA probes by IRE1α and stably binds its kinase domain. However, AK177 displays poor kinase selectivity, and due to inadequate membrane permeability, shows negligible downstream pathway activation and antiproliferative activity at the cellular level.c-Kit-IN-6
C-Kit-IN-6 (Compound 101) is an inhibitor of c-Kit, demonstrating IC50 values ranging from 100 nM to 1 μM.Fórmula:C25H28FN5O5Cor e Forma:SolidPeso molecular:497.52Multi-kinase-IN-5
Multi-kinase-IN-5 (compound 15c) is a multi-kinase inhibitory agent that shows significant inhibition against a range of protein kinases including RET, KIT,Fórmula:C19H15N5O2SCor e Forma:SolidPeso molecular:377.42Motesanib Diphosphate
CAS:Motesanib Diphosphate (AMG 706) is the orally bioavailable diphosphate salt of a multiple-receptor tyrosine kinase inhibitor with potential antineoplasticFórmula:C22H23N5O·2H3PO4Pureza:99.69%Cor e Forma:SolidPeso molecular:569.44Amuvatinib hydrochloride
CAS:Amuvatinib HCl (MP470 HCl) is a multi-targeted oral tyrosine kinase inhibitor and hinders RAD51-mediated DNA repair, exhibiting anticancer properties.Fórmula:C23H22ClN5O3SPureza:98%Cor e Forma:SolidPeso molecular:483.97M4205
CAS:M4205 is an inhibitor of c-Kit exhibiting high activity on c-Kit mutations in exons 11, 13, 17.Fórmula:C29H32N8OPureza:99.07%Cor e Forma:Yellow SolidPeso molecular:508.6174Anti-C-Kit Antibody-PE (7P530)
Anti-C-Kit Antibody-PE (7P530) is a PE-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-PE (7P530) can be used in FCM.Cor e Forma:Odour LiquidAnti-C-Kit Antibody-APC (1R766)
Anti-C-Kit Antibody-APC (1R766) is a APC-conjugated Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody-APC (1R766) can be used in FCM.Cor e Forma:Odour LiquidAnti-C-Kit Antibody (1R766)
Anti-C-Kit Antibody (1R766) is a Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody (1R766) can be used in FCM.Cor e Forma:Odour LiquidAnti-C-Kit Antibody-HRP (2T761)
Anti-C-Kit Antibody-HRP (2T761) is a HRP-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-HRP (2T761) can be used in ELISA.Cor e Forma:Odour LiquidAnti-C-Kit Antibody-FITC (8E724)
Anti-C-Kit Antibody-FITC (8E724) is a FITC-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-FITC (8E724) can be used in FCM.Cor e Forma:Odour Liquid
