c-Kit
Os inibidores de c-Kit são compostos que bloqueiam a atividade do Receptor do Fator de Células-Tronco (c-Kit), uma tirosina quinase que desempenha um papel crucial na sobrevivência, proliferação e diferenciação celular, particularmente em células hematopoéticas. As mutações em c-Kit estão ligadas a vários tipos de câncer, incluindo tumores estromais gastrointestinais (GIST) e leucemia. Na CymitQuimica, oferecemos inibidores de c-Kit para apoiar sua pesquisa em oncologia, hematologia e biologia de células-tronco.
Foram encontrados 116 produtos de "c-Kit"
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Lenvatinib
CAS:Lenvatinib (E7080) is a multi-target receptor tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, KIT, PDGFR, and RET, and has oral activity.Fórmula:C21H19ClN4O4Pureza:98.46% - 99.96%Cor e Forma:SolidPeso molecular:426.85JI6
CAS:JI6 (JAK3 Inhibitor VI) is a potent, selective and orally active FLT3 inhibitor.
Fórmula:C19H17N3O4SPureza:98.51%Cor e Forma:SoildPeso molecular:383.42N-Desmethyl imatinib
CAS:N-Desmethyl imatinib (Imatinib metabolite N-Desmethyl imatinib) is a metabolite of Imatinib, which is a multi-target inhibitor of c-Kit, v-Abl, and PDGFR.Fórmula:C28H29N7OPureza:98.60%Cor e Forma:Off-White To Pale-Yellow SolidPeso molecular:479.58Ref: TM-T11641
1mg92,00€5mg170,00€10mg319,00€25mg540,00€50mg777,00€100mg1.074,00€1mL*10mM (DMSO)178,00€Pazopanib
CAS:Pazopanib (GW786034) is an inhibitor of protein tyrosine kinases that inhibits VEGFR1/2/3. Pazopanib has antitumor activity. Cost-effective and quality-assured.Fórmula:C21H23N7O2SPureza:98.78% - 99.85%Cor e Forma:White PowderPeso molecular:437.52Ref: TM-T0097L
10mg49,00€25mg73,00€50mg96,00€100mg145,00€200mg236,00€500mg331,00€1mL*10mM (DMSO)59,00€Imatinib Mesylate
CAS:Imatinib Mesylate (STI-571) is a tyrosine kinase receptor inhibitor with antineoplastic activity (IC50s: 0.6 μM, 0.1 μM and 0.1 μM for v-Abl, c-Kit and PDGFR,
Fórmula:C29H31N7O·CH4SO3Pureza:98% - >99.99%Cor e Forma:White Crystalline PowderPeso molecular:589.71Axitinib
CAS:Axitinib (AG-013736) is a multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1/2/3 and PDGFRβ. Axitinib has antitumor activity. Cost-effective and quality-assured.Fórmula:C22H18N4OSPureza:98.9% - 99.74%Cor e Forma:Off-White SolidPeso molecular:386.47Amuvatinib hydrochloride
CAS:Amuvatinib HCl (MP470 HCl) is a multi-targeted oral tyrosine kinase inhibitor and hinders RAD51-mediated DNA repair, exhibiting anticancer properties.Fórmula:C23H22ClN5O3SPureza:98%Cor e Forma:SolidPeso molecular:483.97Motesanib Diphosphate
CAS:Motesanib Diphosphate (AMG 706) is the orally bioavailable diphosphate salt of a multiple-receptor tyrosine kinase inhibitor with potential antineoplasticFórmula:C22H23N5O·2H3PO4Pureza:99.69%Cor e Forma:SolidPeso molecular:569.44c-Kit-IN-6
C-Kit-IN-6 (Compound 101) is an inhibitor of c-Kit, demonstrating IC50 values ranging from 100 nM to 1 μM.Fórmula:C25H28FN5O5Cor e Forma:SolidPeso molecular:497.52Multi-kinase-IN-5
Multi-kinase-IN-5 (compound 15c) is a multi-kinase inhibitory agent that shows significant inhibition against a range of protein kinases including RET, KIT,Fórmula:C19H15N5O2SCor e Forma:SolidPeso molecular:377.42Eglatoprutug
CAS:Eglatoprutug is a humanized immunoglobulin G1-kappa monoclonal antibody targeting the c-Kit receptor [1].Cor e Forma:LiquidKG5
CAS:KG5 inhibits PDGFRβ, B-Raf, FLT3, KIT, c-Raf; has anticancer and antiangiogenic effects; Kd: 520 nM (PDGFRβ), 300 nM (PDGFRα).
Fórmula:C20H16F3N7OSPureza:98.32%Cor e Forma:SolidPeso molecular:459.45M4205
CAS:M4205 is an inhibitor of c-Kit exhibiting high activity on c-Kit mutations in exons 11, 13, 17.Fórmula:C29H32N8OPureza:99.07%Cor e Forma:SolidPeso molecular:508.62Ref: TM-T9689
1mg52,00€5mg116,00€10mg178,00€25mg306,00€50mg437,00€100mg605,00€200mg815,00€1mL*10mM (DMSO)129,00€Anti-C-Kit Antibody-APC (8E724)
Anti-C-Kit Antibody-APC (8E724) is a APC-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-APC (8E724) can be used in FCM.Cor e Forma:Odour LiquidN-Desethyl Sunitinib
CAS:N-Desethyl Sunitinib (SU012662) is inhibitor of tyrosine kinases tumor proliferation and angiogenesis, including VEGFR, PDGFR, KIT, and FLT3,Fórmula:C20H23FN4O2Pureza:98%Cor e Forma:SolidPeso molecular:370.42SU14813 maleate
CAS:SU14813 maleate is an inhibitor of multi-targeted receptor tyrosine kinases (IC50s: 2, 50, 4, 15 nM for VEGFR1, VEGFR2, PDGFRβ, and KIT).Fórmula:C27H31FN4O8Pureza:98%Cor e Forma:SolidPeso molecular:558.56Anti-C-Kit Antibody (2T761)
Anti-C-Kit Antibody (2T761) is a Mouse antibody targeting C-Kit. Anti-C-Kit Antibody (2T761) can be used in ELISA(Det).Cor e Forma:Odour LiquidAnti-C-Kit Antibody (9Y519)
Anti-C-Kit Antibody (9Y519) is a Mouse antibody targeting C-Kit. Anti-C-Kit Antibody (9Y519) can be used in ELISA.Cor e Forma:Odour LiquidAnti-C-Kit Antibody-FITC (7P530)
Anti-C-Kit Antibody-FITC (7P530) is a FITC-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-FITC (7P530) can be used in FCM.Cor e Forma:Odour LiquidAnti-CD117 Antibody (9H202)
Anti-CD117 Antibody (9H202) is an antibody targeting CD117. Anti-CD117 Antibody (9H202) can be used in ELISA, IHC, FCM.Cor e Forma:Odour LiquidAnti-C-Kit Antibody (8E724)
Anti-C-Kit Antibody (8E724) is a Mouse antibody targeting C-Kit. Anti-C-Kit Antibody (8E724) can be used in FCM.Cor e Forma:Odour LiquidAnti-C-Kit Antibody-PE (8E724)
Anti-C-Kit Antibody-PE (8E724) is a PE-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-PE (8E724) can be used in FCM.Cor e Forma:Odour LiquidAnti-C-Kit Antibody (3F840)
Anti-C-Kit Antibody (3F840) is a Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody (3F840) can be used in ELISA,IHC-P.Cor e Forma:Odour LiquidAnti-C-Kit Antibody-HRP (2T761)
Anti-C-Kit Antibody-HRP (2T761) is a HRP-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-HRP (2T761) can be used in ELISA.Cor e Forma:Odour LiquidAnti-C-Kit Antibody (1R766)
Anti-C-Kit Antibody (1R766) is a Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody (1R766) can be used in FCM.Cor e Forma:Odour LiquidAnti-C-Kit Antibody-FITC (8E724)
Anti-C-Kit Antibody-FITC (8E724) is a FITC-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-FITC (8E724) can be used in FCM.Cor e Forma:Odour LiquidAnti-C-Kit Antibody (7P530)
Anti-C-Kit Antibody (7P530) is a Mouse antibody targeting C-Kit. Anti-C-Kit Antibody (7P530) can be used in FCM.Cor e Forma:Odour LiquidAnti-C-Kit Antibody-PE (7P530)
Anti-C-Kit Antibody-PE (7P530) is a PE-conjugated Mouse antibody targeting C-Kit. Anti-C-Kit Antibody-PE (7P530) can be used in FCM.Cor e Forma:Odour LiquidAnti-C-Kit Antibody-APC (1R766)
Anti-C-Kit Antibody-APC (1R766) is a APC-conjugated Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody-APC (1R766) can be used in FCM.Cor e Forma:Odour LiquidAnti-C-Kit Antibody (3N57)
Anti-C-Kit Antibody (3N57) is a Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody (3N57) can be used in ELISA(Cap).Cor e Forma:Odour Liquidc-Kit/CD117 Protein, Human, Recombinant (hFc)
c-Kit Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Pureza:97.1%Cor e Forma:Lyophilized PowderPeso molecular:82 kDa (predicted); 93-115 kDa (reducing conditions)c-Kit/CD117 Protein, Human, Recombinant (aa 540-972, His & GST)
c-Kit Protein, Human, Recombinant (aa 540-972, His & GST) is expressed in Baculovirus insect cells with His and GST tag.Cor e Forma:Lyophilized PowderPeso molecular:76.8 kDa (predicted); 68 kDa (reducing conditions)c-Kit/CD117 Protein, Mouse, Recombinant (hFc)
c-Kit Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Cor e Forma:Lyophilized PowderPeso molecular:82.5 kDa (predicted); 100-110 kDa (reducing condition, due to glycosylation)PLX647
CAS:PLX647 is a highly selective dual FMS/KIT kinase inhibitor (IC50: 28/16 nM).Fórmula:C21H17F3N4Pureza:99.38%Cor e Forma:SolidPeso molecular:382.38Ref: TM-T1925
2mg42,00€5mg60,00€10mg90,00€25mg134,00€50mg188,00€100mg279,00€200mg411,00€1mL*10mM (DMSO)64,00€Telatinib mesylate
CAS:Telatinib mesylate is a potent, orally active inhibitor of VEGFR2 (IC50: 6 nM), VEGFR3 (IC50: 4 nM), PDGFα (IC50: 15 nM) and c-Kit (IC50: 1 nM).Fórmula:C21H20ClN5O6SCor e Forma:SolidPeso molecular:505.93c-Kit/CD117 Protein, Mouse, Recombinant (His)
c-Kit Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Pureza:98.2%Cor e Forma:Lyophilized PowderPeso molecular:57 kDa (predicted); 70-80 kDa (reducing condition, due to glycosylation)c-Kit/CD117 Protein, Human, Recombinant (aa 50-190, His)
c-Kit Protein, Human, Recombinant (aa 50-190, His) is expressed in E.Cor e Forma:Lyophilized PowderPeso molecular:17.9 kDa (predicted); 18 kDa (reducing conditions)c-Kit/CD117 Protein, Mouse, Recombinant (His)
The c-kit proto-oncogen (CD 117) has been shown to be present in several cell types including normal and neoplastic hemopoietic cells.Cor e Forma:Lyophilized PowderPeso molecular:56.63 kDa (predicted). Due to glycosylation, the protein migrates to 75-100 kDa based on Tris-Bis PAGE result.c-Kit/CD117 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
The c-kit proto-oncogen (CD117) has been shown to be present in several cell types including normal and neoplastic hemopoietic cells.Cor e Forma:Lyophilized PowderPeso molecular:56.69 kDa (predicted). Due to glycosylation, the protein migrates to 90-110 kDa based on Tris-Bis PAGE result.c-Kit/CD117 Protein, Human, Recombinant (His)
c-Kit Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Pureza:99.4%Cor e Forma:Lyophilized PowderPeso molecular:56.7 kDa (predicted); 86 kDa (reducing condition, due to glycosylation)Anti-C-Kit Antibody (6X205)
Anti-C-Kit Antibody (6X205) is a Mouse antibody targeting C-Kit. Anti-C-Kit Antibody (6X205) can be used in ELISA.Cor e Forma:Odour LiquidAnti-C-Kit Antibody (3B930)
Anti-C-Kit Antibody (3B930) is a Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody (3B930) can be used in WB,ELISA,IP.Cor e Forma:Odour LiquidAnti-C-Kit Antibody-PE (1R766)
Anti-C-Kit Antibody-PE (1R766) is a PE-conjugated Rabbit antibody targeting C-Kit. Anti-C-Kit Antibody-PE (1R766) can be used in FCM.Cor e Forma:Odour LiquidDovitinib
CAS:Dovitinib is an orally active, multi-targeted tyrosine kinase (RTK) inhibitor with anti-tumor effects.Cost-effective and quality-assured.
Fórmula:C21H21FN6OPureza:99.35% - 99.92%Cor e Forma:SolidPeso molecular:392.43ISCK03
CAS:ISCK03 is a selective SCF/c-Kit inhibitor.Fórmula:C19H21N3O2SPureza:98.39%Cor e Forma:SolidPeso molecular:355.45JNJ-38158471
CAS:JNJ-38158471 (CS-2660), a highly selective, orally available, well tolerated VEGFR2 inhibitor, inhibits closely related tyrosine kinases such as Ret and Kit .Fórmula:C15H17ClN6O3Pureza:97.08%Cor e Forma:SolidPeso molecular:364.79Ref: TM-T22349
1mg38,00€5mg78,00€10mg103,00€25mg172,00€50mg250,00€100mg338,00€200mg464,00€1mL*10mM (DMSO)84,00€OSI-930
CAS:OSI-930 is an oral c-Kit/VEGFR-2 inhibitor targeting tumor growth and angiogenesis.Fórmula:C22H16F3N3O2SPureza:99.67%Cor e Forma:SolidPeso molecular:443.44Masitinib
CAS:Masitinib (AB1010) is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs.Fórmula:C28H30N6OSPureza:97.56% - >99.99%Cor e Forma:SolidPeso molecular:498.64Toceranib Phosphate
CAS:Toceranib Phosphate (SU11654 phosphate), is a selective inhibitor of the tyrosine kinase activity of several members of the split kinase RTK family.Fórmula:C22H28FN4O6PPureza:98.56%Cor e Forma:SolidPeso molecular:494.45BLU-263
CAS:BLU-263 is an investigational, potent, and selective oral small molecule inhibitor of KIT with sub-nanomolar potency against D816V-mutant KIT.Fórmula:C27H29FN10OPureza:99.01% - 99.67%Cor e Forma:SolidPeso molecular:528.58Ripretinib
CAS:Ripretinib (DCC-2618) is an orally bioavailable inhibitor of KIT and PDGFRA.Fórmula:C24H21BrFN5O2Pureza:99.07% - 99.62%Cor e Forma:SolidPeso molecular:510.36Ref: TM-T8482
1mg74,00€2mg97,00€5mg165,00€10mg274,00€25mg432,00€50mg692,00€100mg1.121,00€200mg1.539,00€1mL*10mM (DMSO)202,00€SU14813
CAS:SU14813: inhibits multiple kinases (VEGFR2, VEGFR1, PDGFRβ, KIT) with IC50s of 50, 2, 4, 15 nM; antiangiogenic and antitumor.Fórmula:C23H27FN4O4Pureza:98.13%Cor e Forma:SolidPeso molecular:442.48Avapritinib
CAS:Avapritinib (BLU-285) is a selective, highly potent, and orally active inhibitor of KIT and PDGFRA activation loop mutant kinases.Cost-effective and quality-assured.Fórmula:C26H27FN10Pureza:96.59% - 99.7%Cor e Forma:SolidPeso molecular:498.56Ref: TM-T5109
1mg38,00€5mg80,00€10mg120,00€25mg235,00€50mg354,00€100mg588,00€200mg833,00€1mL*10mM (DMSO)175,00€Multi-kinase inhibitor 1
CAS:Multi-kinase inhibitor 1 (Multi-kinase inhibitor I) is a Multi-kinase inhibitor.Fórmula:C20H17F3N4O3Pureza:99.34%Cor e Forma:SolidPeso molecular:418.37Ref: TM-T4191
1mg37,00€2mg52,00€5mg79,00€10mg101,00€25mg177,00€50mg268,00€100mg385,00€1mL*10mM (DMSO)87,00€Ki20227
CAS:Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM).Fórmula:C24H24N4O5SPureza:98.97% - 99.88%Cor e Forma:SolidPeso molecular:480.54Ref: TM-T4315
1mg47,00€5mg96,00€10mg154,00€25mg283,00€50mg464,00€100mg740,00€200mg1.008,00€1mL*10mM (DMSO)96,00€Flumatinib
CAS:Flumatinib (HHGV678) is an orally bioavailable tyrosine kinase inhibitor flumatinib, with potential antineoplastic activity.Fórmula:C29H29F3N8OPureza:99.39% - 99.95%Cor e Forma:SolidPeso molecular:562.59Ref: TM-T4320
1mg34,00€5mg63,00€10mg82,00€25mg120,00€50mg155,00€100mg259,00€200mg388,00€500mg642,00€1mL*10mM (DMSO)82,00€AZD2932
CAS:AZD2932 is a potent and multi-targeted kinase inhibitor VEGFR2, PDGFβ, Flt-3, and c-Kit.Fórmula:C24H25N5O4Pureza:97.71% - 98.37%Cor e Forma:SolidPeso molecular:447.49AZD3229 Tosylate
CAS:AZD3229 Tosylate is a highly potent inhibitor targeting mutant forms of the pan-KIT enzyme, with a primary application in the treatment of gastrointestinalFórmula:C31H34FN7O6SCor e Forma:SolidPeso molecular:651.71Midostaurin
CAS:PKC412(Midostaurin (PKC412); CGP41231; CGP41251) is a broad spectrum protein kinase inhibitor.Fórmula:C35H30N4O4Pureza:97.61% - >99.99%Cor e Forma:SolidPeso molecular:570.64Ref: TM-T3211
1mg51,00€5mg88,00€10mg126,00€25mg216,00€50mg328,00€100mg487,00€500mg1.093,00€1mL*10mM (DMSO)96,00€Dovitinib lactate
CAS:Dovitinib lactate (TKI-258 lactate)(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).Fórmula:C24H27FN6O4Pureza:99.54% - 99.77%Cor e Forma:SolidPeso molecular:482.51Ref: TM-T7104
5mg51,00€10mg79,00€25mg129,00€50mg213,00€100mg358,00€200mg535,00€500mg843,00€1mL*10mM (DMSO)57,00€Tandutinib
CAS:Tandutinib (CT53518) (MLN518, CT53518), an effective FLT3 antagonist (IC50: 0.22 μM), can also inhibit c-Kit and PDGFR, 15-20 fold higher potency for FLT3Fórmula:C31H42N6O4Pureza:99.45% - ≥98%Cor e Forma:White SolidPeso molecular:562.7Vimseltinib
CAS:Vimseltinib (DCC-3014) is a c-FMS (CSF-IR) and c-Kit dual inhibitor (IC50s: <0.01 μM and 0.1-1 μM).Fórmula:C23H25N7O2Pureza:99.05% - 99.57%Cor e Forma:SolidPeso molecular:431.49Ref: TM-T10652
1mg87,00€5mg178,00€10mg295,00€25mg505,00€50mg690,00€100mg888,00€1mL*10mM (DMSO)203,00€SKLB4771
CAS:SKLB4771 (FLT3-IN-1) is a novel potent and selective Flt3 inhibitor.Fórmula:C25H27N7O3S2Pureza:98% - >99.99%Cor e Forma:SolidPeso molecular:537.66Ref: TM-T2051
1mg63,00€2mg93,00€5mg124,00€10mg177,00€25mg371,00€50mg557,00€100mg792,00€500mg1.611,00€1mL*10mM (DMSO)148,00€AZD3229
CAS:AZD3229 is a potent pan-KIT mutant inhibitor for the treatment of gastrointestinal stromal tumors.Fórmula:C24H26FN7O3Pureza:98.83%Cor e Forma:SolidPeso molecular:479.51Ref: TM-T5409
1mg44,00€5mg87,00€10mg140,00€25mg248,00€50mg364,00€100mg509,00€200mg698,00€1mL*10mM (DMSO)99,00€c-Kit-IN-1
CAS:c-Kit-IN-1 (DCC-2618) is an effective inhibitor of c-Met and c-Kit (IC50s<200 nM).Fórmula:C26H21F2N5O3Pureza:98.72% - 98.73%Cor e Forma:SolidPeso molecular:489.47Ref: TM-T4332
1mg39,00€5mg81,00€10mg120,00€25mg235,00€50mg373,00€100mg610,00€200mg840,00€1mL*10mM (DMSO)88,00€Imatinib
CAS:Imatinib (STI571) is a multi-targeted receptor tyrosine kinase inhibitor that selectively inhibits the kinase activities of BCR/ABL, v-Abl, PDGFR, and c-kitFórmula:C29H31N7OPureza:99.42% - 99.94%Cor e Forma:Off White PowderPeso molecular:493.6Telatinib
CAS:Telatinib (Bay 57-9352) inhibits VEGFR2/3, c-Kit, PDGFRα with IC50s: 6 nM, 4 nM, 1 nM, 15 nM.Fórmula:C20H16ClN5O3Pureza:97.61% - 99.81%Cor e Forma:SolidPeso molecular:409.83Linifanib
CAS:Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) andFórmula:C21H18FN5OPureza:98% - 98.24%Cor e Forma:SolidPeso molecular:375.4Ref: TM-T2514
5mg50,00€10mg85,00€25mg126,00€50mg188,00€100mg274,00€200mg505,00€500mg815,00€1mL*10mM (DMSO)52,00€GW786034B
CAS:Pazopanib HCl (Votrient) inhibits VEGFR1-3, PDGFR, FGFR, c-Kit, c-Fms with IC50 range 10-146 nM in cell-free assays.Fórmula:C21H23N7O2S·HClPureza:99.87%Cor e Forma:SolidPeso molecular:473.98Ref: TM-T6930
10mg44,00€25mg70,00€50mg96,00€100mg140,00€200mg229,00€500mg329,00€1mL*10mM (DMSO)34,00€N-Desethylsunitinib hydrochloride
CAS:N-Desethylsunitinib HCl, active sunitinib metabolite, inhibits VEGFR, PDGFRβ, KIT.Fórmula:C20H24ClFN4O2Pureza:99.42%Cor e Forma:SolidPeso molecular:406.88JNK-IN-8
CAS:JNK-IN-8 (JNK Inhibitor XVI) is an irreversible JNK1/2/4 inhibitor (IC50: 4.7/18.7/1 nM).Fórmula:C29H29N7O2Pureza:99.24% - >99.99%Cor e Forma:SolidPeso molecular:507.59Ref: TM-T2668
2mg47,00€5mg77,00€10mg119,00€25mg207,00€50mg344,00€100mg510,00€200mg722,00€1mL*10mM (DMSO)87,00€CP-673451
CAS:CP-673451 is a specific inhibitor of PDGFRα/β (IC50: 10/1 nM) with antiangiogenic and antitumor activity and the selectivity is higher 450-fold than otherFórmula:C24H27N5O2Pureza:99.62% - 99.88%Cor e Forma:SolidPeso molecular:417.5Ref: TM-T6091
1mg52,00€2mg66,00€5mg96,00€10mg180,00€25mg354,00€50mg540,00€100mg778,00€500mg1.605,00€1mL*10mM (DMSO)114,00€KI8751
CAS:KI8751 is a potent and selective inhibitor of VEGFR2 with IC50 of 0.9 nM.Fórmula:C24H18F3N3O4Pureza:99.22% - 99.9%Cor e Forma:SolidPeso molecular:469.41Ref: TM-T2446
2mg37,00€5mg52,00€10mg86,00€25mg156,00€50mg294,00€100mg472,00€200mg670,00€1mL*10mM (DMSO)56,00€GNF-5837
CAS:GNF-5837 is a specific, and orally bioavailable pan-TRK inhibitor for TrkA/TrkB (IC50: 8/12 nM).Fórmula:C28H21F4N5O2Pureza:97.26% - 98.08%Cor e Forma:SolidPeso molecular:535.49Ref: TM-T6097
5mg48,00€10mg80,00€25mg117,00€50mg178,00€100mg295,00€200mg384,00€500mg622,00€1mL*10mM (DMSO)52,00€Motesanib
CAS:Motesanib (AMG 706) orally blocks VEGFR, PDGFR, Kit, Ret; curbing angiogenesis and cancer cell growth.Fórmula:C22H23N5OPureza:98% - 99.09%Cor e Forma:SolidPeso molecular:373.45Ref: TM-T2288
5mg34,00€10mg49,00€25mg81,00€50mg114,00€100mg160,00€200mg230,00€500mg389,00€1mL*10mM (DMSO)39,00€Regorafenib
CAS:Regorafenib (BAY 73-4506) is a multi-targeted receptor tyrosine kinase inhibitor that inhibits RET, C-RAF, VEGFR2, c-Kit, VEGFR1, and PDGFRβ and is orallyFórmula:C21H15ClF4N4O3Pureza:98% - 99.95%Cor e Forma:SolidPeso molecular:482.82Ref: TM-T1792
5mg35,00€10mg51,00€25mg80,00€50mg96,00€100mg144,00€200mg185,00€500mg309,00€1mL*10mM (DMSO)57,00€Lenvatinib mesylate
CAS:Lenvatinib mesylate (E7080 (mesylate)) is an oral and multi-targeted inhibitor of VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, with potent antitumor activities.Fórmula:C22H23ClN4O7SPureza:99.03% - 99.79%Cor e Forma:SolidPeso molecular:522.96Tyrphostin AG1296
CAS:Tyrphostin AG1296 (Tyrphostin AG 1296) is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity to EGFR.Fórmula:C16H14N2O2Pureza:99.94% - >99.99%Cor e Forma:SolidPeso molecular:266.29Ref: TM-T6711
2mg40,00€5mg58,00€10mg90,00€25mg180,00€50mg279,00€100mg411,00€200mg585,00€1mL*10mM (DMSO)81,00€Dovitinib lactate hydrate
CAS:Dovitinib lactate hydrate (TKI258) is the Lactate of Dovitinib, which is a multitargeted RTK inhibitor, mostly for class III (FLT3/c-Kit).Fórmula:C24H27FN6O4Pureza:99.82%Cor e Forma:SolidPeso molecular:482.51Amuvatinib
CAS:Amuvatinib (MP470) is an orally bioavailable synthetic carbothioamide with potential antineoplastic activity.Fórmula:C23H21N5O3SPureza:99.38% - >99.99%Cor e Forma:SolidPeso molecular:447.51Pexidartinib
CAS:Pexidartinib (PLX-3397) is a capsule formulation containing a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potentialFórmula:C20H15ClF3N5Pureza:98.34% - 99.45%Cor e Forma:SolidPeso molecular:417.81Ref: TM-T2115
5mg46,00€10mg58,00€25mg90,00€50mg114,00€100mg145,00€200mg192,00€500mg333,00€1mL*10mM (DMSO)49,00€Cabozantinib
CAS:Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM).
Fórmula:C28H24FN3O5Pureza:99.68% - 99.88%Cor e Forma:SolidPeso molecular:501.51Flumatinib mesylate
CAS:Flumatinib mesylate (HHGV678 mesylate) is a selective inhibitor of c-Abl, PDGFRβ and c-Kit, effectively overcomes drug resistance of certain KIT mutants.Fórmula:C30H33F3N8O4SPureza:99.82%Cor e Forma:SolidPeso molecular:658.69Ref: TM-T7861
1mg34,00€5mg84,00€10mg126,00€25mg236,00€50mg371,00€100mg595,00€500mg1.234,00€1mL*10mM (DMSO)132,00€Cabozantinib hydrochloride
CAS:Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6
Fórmula:C28H25ClFN3O5Pureza:99.97%Cor e Forma:SolidPeso molecular:537.96Ref: TM-T5164
1mg44,00€2mg55,00€5mg69,00€10mg97,00€25mg169,00€50mg248,00€100mg349,00€200mg568,00€500mg908,00€Masitinib mesylate
CAS:Masitinib mesylate (AB-1010 mesylate) is a selective and orally bioavailable c-Kit inhibitor (IC50 of 200 nM,540/800 nM,510 nM for human recombinant c-Kit;Fórmula:C29H34N6O4S2Pureza:97.67% - 98.44%Cor e Forma:SolidPeso molecular:594.75Sitravatinib
CAS:Sitravatinib (MGCD516) (MGCD516) is an inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, including c-Met, c-Kit, PDGFRα/β, PDGFR, andFórmula:C33H29F2N5O4SPureza:98.9% - 99.85%Cor e Forma:SolidPeso molecular:629.68Ref: TM-T4349
5mg51,00€10mg79,00€25mg137,00€50mg210,00€100mg338,00€200mg535,00€500mg845,00€1mL*10mM (DMSO)72,00€AST 487
CAS:AST 487 (NVP-AST 487) is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of downstream effectors. It also can inhibit Flt-3.Fórmula:C26H30F3N7O2Pureza:98.17% - 99.56%Cor e Forma:SolidPeso molecular:529.56Ref: TM-T4053
1mg37,00€2mg52,00€5mg79,00€10mg119,00€25mg187,00€50mg354,00€100mg528,00€500mg1.159,00€1mL*10mM (DMSO)92,00€c-Kit/CD117 Protein, Human, Recombinant (His & Avi), Biotinylated
The c-kit proto-oncogen (CD 117) has been shown to be present in several cell types including normal and neoplastic hemopoietic cells.Cor e Forma:Lyophilized PowderPeso molecular:58.60 kDa (predicted). Due to glycosylation, the protein migrates to 75-105 kDa based on Tris-Bis PAGE result.Ref: TM-TMPK-00805
5µg89,00€10µg145,00€20µg233,00€50µg459,00€100µg772,00€200µg1.396,00€500µg3.087,00€Toceranib
CAS:Toceranib phosphate, orally active, inhibits RTK, PDGFR, VEGFR, Kit; Kis 5 nM PDGFRβ, 6 nM KDR; has antitumor effects.Fórmula:C22H25FN4O2Pureza:97.62%Cor e Forma:SolidPeso molecular:396.46Briquilimab
CAS:Briquilimab is a humanized antibody that inhibits the SCF-KIT interaction, inducing mast cell apoptosis for research into inflammatory diseases.Pureza:95% - 96.0% (SDS-PAGE); 96.0% (SEC-HPLC)Cor e Forma:LiquidAnti-Mouse CD117 Antibody
Anti-Mouse CD117 Antibody, a rat-derived IgG2b isotype, acts as an inhibitor specific to the mouse CD117 antigen.Pureza:98%Cor e Forma:Odour SolidBarzolvolimab
CAS:Barzolvolimab (CDX 0159) is a humanized monoclonal antibody targeting KIT that reduces skin mast cells and disease activity in chronic inducible urticaria.Pureza:95% - 95.6% (SDS-PAGE); 95.4% (SEC-HPLC)Cor e Forma:LiquidPeso molecular:144.63 kDaDovitinib Dilactic Acid
CAS:Dovitinib dilactic acid: multitarget RTK inhibitor for FLT3/c-Kit (IC50=1-2 nM), FGFR1/3, VEGFR1-4 (IC50=8-13 nM), less effective on InsR, EGFR. Phase 4.Fórmula:C21H21FN6O·2C3H6O3Pureza:98%Cor e Forma:SolidPeso molecular:572.59c-Kit-IN-2
CAS:c-Kit-IN-2 is a c-KIT inhibitor (IC50: 82 nM), shows superior antiproliferative activities against all the three GIST cell lines, GIST430, GIST882, and GIST48 (Fórmula:C25H29N9O2SPureza:98%Cor e Forma:SolidPeso molecular:519.62Sitravatinib malate
CAS:Sitravatinib malate is an orally bioavailable receptor inhibitor of tyrosine kinase (RTK) (IC50s of 1.5 nM, 2 nM, 2 nM, 5 nM, 6 nM, 6 nM, 8 nM, 0.5 nM, 29 nM, 5
Fórmula:C37H35F2N5O9SPureza:98%Cor e Forma:SolidPeso molecular:763.76c-Kit-IN-3
CAS:c-Kit-IN-3 is a selective inhibitor of c-KIT kinase with IC50s of 4 nM and 8 nM for c-Kit (wt) and c-Kit (T670I).Fórmula:C26H20ClF3N2O4Pureza:99.94%Cor e Forma:SolidPeso molecular:516.9Ref: TM-T10651
1mg87,00€5mg162,00€10mg254,00€25mg419,00€50mg562,00€100mg787,00€500mg1.578,00€1mL*10mM (DMSO)334,00€APcK110
CAS:"APcK110, a potent novel Kit inhibitor, outperforms imatinib/dasatinib in halting OCI/AML3 and HMC1.2 cell growth, also inhibiting Kit-signaling."Fórmula:C20H16FN3O2Cor e Forma:SolidPeso molecular:349.36GW694590A
CAS:GW694590A (UNC10112731) functions as a MYC protein stabilizer that enhances the levels of endogenous MYC protein. It also acts on receptor tyrosine kinases, inhibiting DDR2, KIT, and PDGFRα by 81%, 68%, and 67% at a concentration of 1 μM, respectively. As a protein kinase inhibitor, GW694590A affects both ATP-dependent and ATP-independent luciferases, potentially influencing the Fluc reporter gene [1].Fórmula:C22H19N5O4Cor e Forma:SolidPeso molecular:417.42KI-328
CAS:KI-328: novel selective KIT kinase inhibitor; blocks Wt/mutant-KIT cell growth; low effect on D816V-KIT.Fórmula:C25H25N7O3Cor e Forma:SolidPeso molecular:471.51KBP-7018 HCl
CAS:KBP-7018 Hydrochloride is a novel, tyrosine kinase-selective inhibitor with potent effects on three fibrotic kinases (c-KIT, PDGFR, and RET).Fórmula:C31H31ClN4O5Cor e Forma:SolidPeso molecular:575.06
