IGF-1R
Os inibidores de IGF-1R são compostos que especificamente alvo e inibem o Receptor do Fator de Crescimento Semelhante à Insulina 1 (IGF-1R), uma tirosina quinase receptora envolvida no crescimento celular, desenvolvimento e sobrevivência. A sinalização de IGF-1R desempenha um papel significativo na progressão do câncer, tornando esses inibidores valiosos na pesquisa oncológica. Na CymitQuimica, oferecemos inibidores de IGF-1R para apoiar sua pesquisa em biologia do câncer, endocrinologia e desenvolvimento de terapias direcionadas.
Foram encontrados 97 produtos de "IGF-1R"
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Ganitumab
CAS:Ganitumab (AMG 479) is a potent monoclonal antibody targeting IGF1R with 0.22 nM affinity; used in cancer research.Pureza:100% (SEC-HPLC) - > 95%Cor e Forma:LiquidPeso molecular:145.70 kDaGIP (human) acetate
GIP (human) acetate boosts insulin, limits gastric acid, affects lipid metabolism, and obesity development.Pureza:98.65%Cor e Forma:SoildAZ7550 hydrochloride
CAS:AZ7550 hydrochloride (AZ7550 hydrochloride ), an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).Fórmula:C27H32ClN7O2Pureza:99.65%Cor e Forma:SolidPeso molecular:522.04MSDC-0602K
CAS:MSDC-0602K, a Ps-TZD, targets PPARγ (IC50: 18.25 μM) and MPC, may help study fatty liver, lipid imbalance, inflammation, and insulin issues.Fórmula:C19H16KNO5SPureza:99.42%Cor e Forma:SolidPeso molecular:409.5GIP (3-42), human
CAS:Human GIP (3-42) is a peptide antagonist of GIP receptors, affecting insulin regulation and diabetes research.Fórmula:C214H324N58O63SPureza:95.73%Cor e Forma:SolidPeso molecular:4749.35ALK inhibitor 1
CAS:ALK inhibitor 1 is a selective ALK kinase inhibitor.Fórmula:C23H28BrN7O3SPureza:98.27%Cor e Forma:SolidPeso molecular:562.48Ref: TM-T10285
1mg50,00€5mg110,00€10mg166,00€25mg323,00€50mg447,00€100mg610,00€1mL*10mM (DMSO)136,00€Insulin peglispro
CAS:Insulin peglispro (BIL) is a basal insulin with a stable, extended activity and may offer improved blood sugar control.Fórmula:C370H566N104O110S4Cor e Forma:SolidPeso molecular:8359.32Acetyl Gastric Inhibitory Peptide (human)
CAS:Acetyl Gastric Inhibitory Peptide: improved insulinotropic, antihyperglycemic, for diabetes/obesity research.Fórmula:C228H340N60O67SCor e Forma:SolidPeso molecular:5025.6(Pro3) GIP, human
CAS:(Pro3) GIP, human: stable hGIPR full agonist, high affinity (Ki/Kd=0.90nM), for obesity-related diabetes research.Fórmula:C226H338N60O64SCor e Forma:SolidPeso molecular:4951.53GIP (1-30) amide,human
CAS:GIP (1-30) amide (Human) is a glucose-dependent insulinotropic polypeptide that stimulates insulin secretion, reducing postprandial glycemic issues.Fórmula:C162H240N40O47SPureza:98%Cor e Forma:SolidPeso molecular:3531.94Gastric Inhibitory Peptide (1-42) (porcine) TFA
Gastric Inhibitory Peptide (1-42) (porcine) TFA is a glucose-dependent insulinotropic polypeptide released by intestinal K-cells.
Fórmula:C225H342N60O66S·XCF3COOHCor e Forma:SolidPeso molecular:4975.55IGF-I (24-41)
CAS:IGF-I (24-41) is a fragment of IGF-I, affecting GH activities with anabolic, antioxidant, anti-inflammatory, and cytoprotective properties.
Fórmula:C88H133N27O28Pureza:98%Cor e Forma:SolidPeso molecular:2017.16OI338
OI338 is an orally available, ultralong-acting insulin analogue.Fórmula:C260H403N65O84S6Cor e Forma:SolidPeso molecular:5971.76cis-NVP-ADW742
CAS:NVP-ADW742 is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl and c-Kit.Fórmula:C28H31N5OCor e Forma:SolidPeso molecular:453.59[Pro3]-GIP (Mouse)
GIP receptor blocker, 2.6μM IC50, hinders insulin release, regulates glucose in ob/ob mice, and enhances glucose tolerance.Fórmula:C225H342N62O64SPureza:98%Cor e Forma:SolidPeso molecular:4971.62WAY-270250
CAS:WAY-270250 is an IGF-1R/SRC inhibitor.Fórmula:C18H16N2O2Pureza:99.97%Cor e Forma:SoildPeso molecular:292.33[D-Ala2]-GIP (human)
CAS:Potent GIP receptor agonist with 630 pM EC50; enhances cAMP, glucose control, insulin, cognition in diabetic/obese animals; neuroprotective in PD model.Fórmula:C226H338N60O66SPureza:98%Cor e Forma:SolidPeso molecular:4983.58AVE1642
AVE1642 is a human IgG monoclonal antibody (mAb) that specifically targets CD221/IGF1R. It has the ability to slow the growth of tumor xenografts and extend the survival of tumor-bearing nude mice. AVE1642 is applicable in the study of advanced solid tumors. Recommended isotype control: HumanIgG1kappa, Isotype Control.Cor e Forma:Odour LiquidIGF-1R inhibitor-2
CAS:IGF-1R inhibitor-2 blocks the insulin-like growth factor-1 receptor, potentially reversing tumor cell transformation and increasing apoptosis susceptibility.Fórmula:C24H24FN7O2Cor e Forma:SolidPeso molecular:461.501GIP, human
CAS:Insulinotropic hormone from K-cells, binds GIP receptors, boosts insulin, affects lipids, and has antiapoptotic properties.
Fórmula:C226H338N60O66SPureza:98%Cor e Forma:SolidPeso molecular:4983.6
