IGF-1R
Os inibidores de IGF-1R são compostos que especificamente alvo e inibem o Receptor do Fator de Crescimento Semelhante à Insulina 1 (IGF-1R), uma tirosina quinase receptora envolvida no crescimento celular, desenvolvimento e sobrevivência. A sinalização de IGF-1R desempenha um papel significativo na progressão do câncer, tornando esses inibidores valiosos na pesquisa oncológica. Na CymitQuimica, oferecemos inibidores de IGF-1R para apoiar sua pesquisa em biologia do câncer, endocrinologia e desenvolvimento de terapias direcionadas.
Foram encontrados 106 produtos para "IGF-1R".
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Insulin Aspart
CAS:Insulin Aspart is a rapid-acting insulin analog with faster absorption than human insulin, improving postprandial glycemic control.Pureza:99.86%Cor e Forma:White Solid[Pro3]-GIP (Mouse)
GIP receptor blocker, 2.6μM IC50, hinders insulin release, regulates glucose in ob/ob mice, and enhances glucose tolerance.Fórmula:C225H342N62O64SPureza:98%Cor e Forma:SolidPeso molecular:4971.62AVE1642
AVE1642 is a human IgG monoclonal antibody (mAb) that specifically targets CD221/IGF1R. It has the ability to slow the growth of tumor xenografts and extend the survival of tumor-bearing nude mice. AVE1642 is applicable in the study of advanced solid tumors. Recommended isotype control: HumanIgG1kappa, Isotype Control.Cor e Forma:Odour LiquidIGF-I (30-41)
CAS:IGF-I (30-41) is amino acids 30 to 41 fragment of Insulin-like Growth Factor I (IGF-I).Fórmula:C51H83N19O19Pureza:98%Cor e Forma:SolidPeso molecular:1266.34TLK19781
CAS:TLK19781 is an insulin receptor modulator.Fórmula:C33H24Cl2N4O13S4Pureza:98%Cor e Forma:SolidPeso molecular:883.73OI338
OI338 is an orally available, ultralong-acting insulin analogue.Fórmula:C260H403N65O84S6Cor e Forma:SolidPeso molecular:5971.76Proinsulin C-Peptide (55-89), human
CAS:Proinsulin, insulin's precursor, has A and B chains linked by a 31 amino acid C-peptide. Enzymes cleave it, yielding insulin and C-peptide.Fórmula:C153H259N49O52Pureza:98%Cor e Forma:SolidPeso molecular:3616.99[pTyr1146][pTyr1150][pTyr1151]Insulin Receptor (1142-1153)
CAS:Insulin Receptor (1142-1153) binds insulin, is a substrate for its kinase, and has research/medical potential.Fórmula:C72H110N19O33P3Pureza:98%Cor e Forma:SolidPeso molecular:1862.67Gastric Inhibitory Peptide (1-42) (porcine) TFA
Gastric Inhibitory Peptide (1-42) (porcine) TFA is a glucose-dependent insulinotropic polypeptide released by intestinal K-cells.Fórmula:C225H342N60O66S·XCF3COOHCor e Forma:White SolidPeso molecular:4975.55[D-Ala2]-GIP (human)
CAS:Potent GIP receptor agonist with 630 pM EC50; enhances cAMP, glucose control, insulin, cognition in diabetic/obese animals; neuroprotective in PD model.Fórmula:C226H338N60O66SPureza:98%Cor e Forma:SolidPeso molecular:4983.58Macupatide
CAS:Macupatide is a gastric inhibitory polypeptide (GIP) receptor agonist, utilized in research related to antidiabetic applications.Cor e Forma:SolidGIP (1-30) amide,human
CAS:GIP (1-30) amide (Human) is a glucose-dependent insulinotropic polypeptide that stimulates insulin secretion, reducing postprandial glycemic issues.Fórmula:C162H240N40O47SPureza:98%Cor e Forma:SolidPeso molecular:3531.94cis-NVP-ADW742
CAS:NVP-ADW742 is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl and c-Kit.Fórmula:C28H31N5OCor e Forma:SolidPeso molecular:453.59LDD39
LDD39, a PROTAC targeting the degradation of RET protein, effectively and persistently degrades total RET (tRET) protein in vivo and inhibits phosphorylated RET (pRET) signaling.Fórmula:C55H59F2N11O6Cor e Forma:SolidPeso molecular:1008.12IGF-1R inhibitor-2
CAS:IGF-1R inhibitor-2 blocks the insulin-like growth factor-1 receptor, potentially reversing tumor cell transformation and increasing apoptosis susceptibility.Fórmula:C24H24FN7O2Cor e Forma:SolidPeso molecular:461.501WAY-270250
CAS:WAY-270250 is an IGF-1R/SRC inhibitor.Fórmula:C18H16N2O2Pureza:99.97%Cor e Forma:Green SolidPeso molecular:292.33LAGIPRA peptide
LAGIPRA peptide is a long-acting agonist of GIP1R. It improves insulin sensitivity by enhancing glucose handling and reduces circulating branched-chain amino acids (BCAA) and keto acids. LAGIPRA peptide holds potential for research in type 2 diabetes.Insulin peglispro
CAS:Insulin peglispro (BIL) is a basal insulin with a stable, extended activity and may offer improved blood sugar control.Fórmula:C370H566N104O110S4Cor e Forma:SolidPeso molecular:8359.32ZIGIR
ZIGIR enables insulin-based sorting of pure alpha and beta cells, revealing zinc(II) in human delta cell granules.Fórmula:C39H40N6O3Pureza:98.34% - 99.32%Cor e Forma:Pink SolidPeso molecular:640.77(Pro3) GIP, human
CAS:(Pro3) GIP, human: stable hGIPR full agonist, high affinity (Ki/Kd=0.90nM), for obesity-related diabetes research.Fórmula:C226H338N60O64SCor e Forma:SolidPeso molecular:4951.53
![[Pro3]-GIP (Mouse)](https://static.cymitquimica.com/products/TM/thumb-webp/TP2020.webp)
![[pTyr1146][pTyr1150][pTyr1151]Insulin Receptor (1142-1153)](https://static.cymitquimica.com/products/TM/thumb-webp/TP1259.webp)
