IGF-1R
Os inibidores de IGF-1R são compostos que especificamente alvo e inibem o Receptor do Fator de Crescimento Semelhante à Insulina 1 (IGF-1R), uma tirosina quinase receptora envolvida no crescimento celular, desenvolvimento e sobrevivência. A sinalização de IGF-1R desempenha um papel significativo na progressão do câncer, tornando esses inibidores valiosos na pesquisa oncológica. Na CymitQuimica, oferecemos inibidores de IGF-1R para apoiar sua pesquisa em biologia do câncer, endocrinologia e desenvolvimento de terapias direcionadas.
Foram encontrados 105 produtos para "IGF-1R".
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Ganitumab
CAS:Ganitumab (AMG 479) is a potent monoclonal antibody targeting IGF1R with 0.22 nM affinity; used in cancer research.Pureza:/ - > 95%Cor e Forma:Transparent LiquidPeso molecular:145.70 kDaNBI-31772
CAS:NBI-31772 (NBI 31772) is the potent inhibitor of insulin-like growth factor-1 binding protein (IGFBP, Ki = 47 nM).Fórmula:C17H11NO7Pureza:99.79%Cor e Forma:Yellow SolidPeso molecular:341.27Robatumumab
CAS:Robatumumab (Sch 717454) is a fully humanized anti-IGF-1R monoclonal antibody with antitumor activity and antiproliferative activity.Pureza:96.9% (SDS-PAGE); 98.1% (SEC-HPLC) - 96.9% (SDS-PAGE); 98.1% (SEC-HPLC)Cor e Forma:Transparent LiquidPeso molecular:145.56 kDaGIP (human) acetate
GIP (human) acetate boosts insulin, limits gastric acid, affects lipid metabolism, and obesity development.Pureza:98.65%Cor e Forma:SolidMSDC-0602K
CAS:MSDC-0602K, a Ps-TZD, targets PPARγ (IC50: 18.25 μM) and MPC, may help study fatty liver, lipid imbalance, inflammation, and insulin issues.Fórmula:C19H16KNO5SPureza:99.42%Cor e Forma:White SolidPeso molecular:409.5ALK inhibitor 1
CAS:ALK inhibitor 1 is a selective ALK kinase inhibitor.Fórmula:C23H28BrN7O3SPureza:98.27%Cor e Forma:White SolidPeso molecular:562.48Ref: TM-T10285
1mg50,00€5mg110,00€1mL*10mM (DMSO)136,00€10mg166,00€25mg323,00€50mg447,00€100mg610,00€Teprotumumab
CAS:Teprotumumab: human antibody, inhibits IGF-1R, used for thyroid eye diseases.Pureza:SDS-PAGE:95.2%;SEC-HPLC:99.6%Cor e Forma:Transparent LiquidPeso molecular:145.62 kDaGIP (3-42), human
CAS:Human GIP (3-42) is a peptide antagonist of GIP receptors, affecting insulin regulation and diabetes research.Fórmula:C214H324N58O63SPureza:95.73%Cor e Forma:SolidPeso molecular:4749.35HNMPA
CAS:HNMPA blocks insulin receptor kinase, halting autophosphorylation; no impact on cAMP protein kinase or PKC.Fórmula:C11H11O4PPureza:99.18%Cor e Forma:SolidPeso molecular:238.18Ref: TM-T21761
1mg48,00€2mg62,00€5mg88,00€1mL*10mM (DMSO)101,00€10mg137,00€25mg285,00€50mg427,00€100mg625,00€500mg1.324,00€AZ7550 hydrochloride
CAS:AZ7550 hydrochloride (AZ7550 hydrochloride ), an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).Fórmula:C27H32ClN7O2Pureza:99.65%Cor e Forma:SolidPeso molecular:522.04ZIGIR
ZIGIR enables insulin-based sorting of pure alpha and beta cells, revealing zinc(II) in human delta cell granules.Fórmula:C39H40N6O3Pureza:98.34% - 99.32%Cor e Forma:Pink SolidPeso molecular:640.77IGF-1R inhibitor-2
CAS:IGF-1R inhibitor-2 blocks the insulin-like growth factor-1 receptor, potentially reversing tumor cell transformation and increasing apoptosis susceptibility.Fórmula:C24H24FN7O2Cor e Forma:SolidPeso molecular:461.501WAY-270250
CAS:WAY-270250 is an IGF-1R/SRC inhibitor.Fórmula:C18H16N2O2Pureza:99.97%Cor e Forma:Green SolidPeso molecular:292.33Gastric Inhibitory Peptide (1-42) (porcine) TFA
Gastric Inhibitory Peptide (1-42) (porcine) TFA is a glucose-dependent insulinotropic polypeptide released by intestinal K-cells.Fórmula:C225H342N60O66S·XCF3COOHCor e Forma:White SolidPeso molecular:4975.55GIP (1-30) amide,human
CAS:GIP (1-30) amide (Human) is a glucose-dependent insulinotropic polypeptide that stimulates insulin secretion, reducing postprandial glycemic issues.Fórmula:C162H240N40O47SPureza:98%Cor e Forma:SolidPeso molecular:3531.94Acetyl Gastric Inhibitory Peptide (human)
CAS:Acetyl Gastric Inhibitory Peptide: improved insulinotropic, antihyperglycemic, for diabetes/obesity research.Fórmula:C228H340N60O67SCor e Forma:SolidPeso molecular:5025.6Insulin Aspart
CAS:Insulin Aspart is a rapid-acting insulin analog with faster absorption than human insulin, improving postprandial glycemic control.Pureza:99.86%Cor e Forma:White SolidGIP, human
CAS:Insulinotropic hormone from K-cells, binds GIP receptors, boosts insulin, affects lipids, and has antiapoptotic properties.Fórmula:C226H338N60O66SPureza:98%Cor e Forma:SolidPeso molecular:4983.6[pTyr1146][pTyr1150][pTyr1151]Insulin Receptor (1142-1153)
CAS:Insulin Receptor (1142-1153) binds insulin, is a substrate for its kinase, and has research/medical potential.Fórmula:C72H110N19O33P3Pureza:98%Cor e Forma:SolidPeso molecular:1862.67[D-Ala2]-GIP (human)
CAS:Potent GIP receptor agonist with 630 pM EC50; enhances cAMP, glucose control, insulin, cognition in diabetic/obese animals; neuroprotective in PD model.Fórmula:C226H338N60O66SPureza:98%Cor e Forma:SolidPeso molecular:4983.58
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