Autofagia
Os inibidores da autofagia têm como alvo o processo celular de autofagia, que envolve a degradação e reciclagem de componentes celulares através dos lisossomas. A autofagia é um mecanismo crítico para a manutenção da homeostase celular, mas sua desregulação está implicada em várias doenças, incluindo câncer, neurodegeneração e infecções. Os inibidores da autofagia podem bloquear este processo, tornando-os ferramentas valiosas para estudar o papel da autofagia nas doenças e desenvolver estratégias terapêuticas. Na CymitQuimica, oferecemos inibidores da autofagia para apoiar sua pesquisa em biologia celular, oncologia e doenças neurodegenerativas.
Foram encontrados 1424 produtos de "Autofagia"
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Maprotiline
CAS:<p>Maprotiline blocks norepinephrine uptake, has antidepressant properties, and fights cancer by inducing apoptosis and inhibiting ERK and CRABP1.</p>Fórmula:C20H23NCor e Forma:SolidPeso molecular:277.4Lucanthone hydrochloride
CAS:<p>Lucanthone hydrochloride is a novel acridine derivative which supresses autophagic degradation and triggers apoptosis in colon cancer cells.</p>Fórmula:C20H25ClN2OSCor e Forma:SolidPeso molecular:376.94Cucurbitacin E
CAS:<p>Cucurbitacin E, from Cucumic melo, inhibits cyclin B1/CDC2, and has neuroprotective, anti-proliferative, anti-cancer, and pain relief properties.</p>Fórmula:C32H44O8Pureza:98.88% - 99.87%Cor e Forma:SolidPeso molecular:556.69Autogramin-2
CAS:<p>Autogramin-2 (tert-butyl 2-(4-isopropoxybenzamido)-6,7-dihydrothiazolo[5,4-c]pyridine-5(4H)-carboxylate) potently inhibits autophagy induced by either</p>Fórmula:C21H27N3O4SPureza:96.25%Cor e Forma:SolidPeso molecular:417.52Vistusertib
CAS:<p>Vistusertib (AZD2014) is an orally bioavailable inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity.</p>Fórmula:C25H30N6O3Pureza:97.08% - 99.06%Cor e Forma:SolidPeso molecular:462.54Trifluoperazine
CAS:<p>Trifluoperazine (trifluoroperazine) is a Dopamine D2 receptor inhibitor(IC50 : 1.2 nM), and Treatment of schizophrenia.</p>Fórmula:C21H24F3N3SPureza:98.3% - 99.46%Cor e Forma:White To Yellowish Crystalline PowderPeso molecular:407.5Vismodegib
CAS:<p>Vismodegib (GDC-0449) is a hedgehog pathway inhibitor (IC50: 3 nM). It also inhibits P-gp (IC50: 3.0 μM), ABCG2 (IC50: 1.4 μM).</p>Fórmula:C19H14Cl2N2O3SPureza:98% - 99.82%Cor e Forma:SolidPeso molecular:421.3PFK-158
CAS:<p>PFK-158 is an effective and specific inhibitor PFKFB3.</p>Fórmula:C18H11F3N2OPureza:95.49% - 99.16%Cor e Forma:SolidPeso molecular:328.29Trametinib
CAS:<p>Trametinib (GSK1120212), an ATP-noncompetitive MEK 1/2 inhibitor (IC50: 0.7/0.9 nM), weakly inhibits >180 kinases.</p>Fórmula:C26H23FIN5O4Pureza:98% - 99.96%Cor e Forma:SolidPeso molecular:615.39Paris saponin VII
CAS:<p>Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.</p>Fórmula:C51H82O21Pureza:99.51% - 99.63%Cor e Forma:SolidPeso molecular:1031.18Levosimendan
CAS:<p>Levosimendan (OR1259) is a calcium sensitizer for acute heart failure, enhancing cardiac contractility without raising calcium levels.</p>Fórmula:C14H12N6OPureza:99.37% - 99.91%Cor e Forma:Yellow Crystalline PowderPeso molecular:280.28Wogonin
CAS:<p>Wogonin (Vogonin) is a cell-permeable and orally available flavonoid that displays anti-inflammatory and anticancer properties.</p>Fórmula:C16H12O5Pureza:98% - 99.8%Cor e Forma:Yellow CrystalPeso molecular:284.26SU9516
CAS:<p>SU9516 is a potent CDK2 inhibitor, with an IC50 of 22 nM, and also has inhibitory effects on CDK1 and CDK4, with IC50s of 40 nM and 200 nM, respectively.</p>Fórmula:C13H11N3O2Pureza:99.34% - 99.87%Cor e Forma:SolidPeso molecular:241.25DBEQ
CAS:<p>DBEQ (JRF 12) is a selective, potent, reversible, and ATP-competitive p97 inhibitor.</p>Fórmula:C22H20N4Pureza:98.93% - ≥95%Cor e Forma:SolidPeso molecular:340.42Nesolicaftor
CAS:<p>Nesolicaftor (PTI-428) specifically enhances cystic fibrosis transmembrane conductance regulator protein synthesis.</p>Fórmula:C18H18N4O4Pureza:99.79%Cor e Forma:SolidPeso molecular:354.36Degrasyn
CAS:<p>Degrasyn (WP1130) inhibits DUBs (USP5, UCH-L1, USP9x, USP14, UCH37) and Bcr/Abl without affecting the 20S proteasome.</p>Fórmula:C19H18BrN3OPureza:98.32% - 99.98%Cor e Forma:SolidPeso molecular:384.2710058-F4
CAS:<p>10058-F4 inhibits c-Myc-Max, blocking c-Myc target gene activation, causing cell-cycle arrest & apoptosis.</p>Fórmula:C12H11NOS2Pureza:98% - 99.87%Cor e Forma:SolidPeso molecular:249.35UBCS039
CAS:<p>UBCS039 is the first synthetic Sirt6 activator(EC50 : 38 μM)</p>Fórmula:C16H13N3Pureza:98.31%Cor e Forma:SolidPeso molecular:247.29Ataluren
CAS:<p>Ataluren (PTC124) is a novel, orally administered drug that targets nonsense mutations.</p>Fórmula:C15H9FN2O3Pureza:99.16% - 99.84%Cor e Forma:SolidPeso molecular:284.24SRT 1720
CAS:<p>SRT 1720 is a selective activator of human SIRT1 (EC1.5: 0.16 μM) and is >230-fold less potent for SIRT2 and SIRT3.</p>Fórmula:C25H23N7OSPureza:98.84%Cor e Forma:SolidPeso molecular:469.56BAY 11-7082
CAS:<p>BAY 11-7082 (BAY 11-7821) is an NF-κB inhibitor that inhibits TNFα-induced IκBα phosphorylation (IC50=10 μM).</p>Fórmula:C10H9NO2SPureza:98% - 99.92%Cor e Forma:SolidPeso molecular:207.25L-779450
CAS:<p>L-779450, an effective, ATP-competitive Raf kinase inhibitor (IC50: 10 nM) , displays >7, >30 and >70-fold selectivity over p38α, GSK3β and Lck respectively.</p>Fórmula:C20H14ClN3OPureza:≥95%Cor e Forma:SolidPeso molecular:347.8Gemcitabine hydrochloride
CAS:<p>Gemcitabine hydrochloride (LY 188011 hydrochloride) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis.</p>Fórmula:C9H11F2N3O4·HClPureza:99.28% - 99.98%Cor e Forma:White Crystalline Granular OdorlessPeso molecular:299.66Vps34-PIK-III
CAS:<p>Vps34-PIK-III (VPS34-IN2), a selective inhibitor of VPS34 enzymatic activity, inhibits autophagy and results in the stabilization of autophagy substrates.</p>Fórmula:C17H17N7Pureza:98.39% - 98.43%Cor e Forma:SolidPeso molecular:319.36Rottlerin
CAS:<p>Rottlerin (NSC-56346), a Mallotus Philippinensis extract, inhibits PKC (3-100 μM IC50); triggers apoptosis by activating caspase 3.</p>Fórmula:C30H28O8Pureza:97.41% - 99.44%Cor e Forma:Orange To Brown PowderPeso molecular:516.54Rosiglitazone hydrochloride
CAS:<p>Rosiglitazone hydrochloride (BRL-49653 HCl) is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the PPAR receptors in fat cells.</p>Fórmula:C18H19N3O3S·HClPureza:99.63% - 99.79%Cor e Forma:SolidPeso molecular:393.89Olaparib
CAS:<p>View and buy Olaparib from TargetMol.Olaparib is a small molecule inhibitor of PARP1/PARP2.Cited in 10 publications.</p>Fórmula:C24H23FN4O3Pureza:98% - >99.99%Cor e Forma:SolidPeso molecular:434.46BL-918
CAS:<p>BL-918 is a potent activator of UNC-51-like kinase 1 (ULK1) with an EC50 of 24.14 nM.</p>Fórmula:C23H15F8N3OSPureza:99.4% - 99.89%Cor e Forma:SolidPeso molecular:533.44TPEN
CAS:<p>TPEN (TPEDA) is a specific cell-permeable heavy metal chelator.</p>Fórmula:C26H28N6Pureza:98% - 99.72%Cor e Forma:White Crystalline PowderPeso molecular:424.54RSVA405
CAS:<p>RSVA405 is an AMPK activator (EC50 = 1 μM), and is STAT3 inhibitor</p>Fórmula:C17H20N4O2Pureza:99.30%Cor e Forma:SolidPeso molecular:312.37Sevelamer hydrochloride
CAS:<p>Sevelamer hydrochloride (Sevelamer HCl) is a phosphate binding drug used to treat hyperphosphatemia via binding to dietary phosphate and prevents its absorption</p>Fórmula:(C3H7N·C3H5ClO·HCl)xPureza:98%Cor e Forma:SolidPeso molecular:186.08Cucurbitacin B
CAS:<p>Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells.</p>Fórmula:C32H46O8Pureza:97.1% - 99.33%Cor e Forma:SolidPeso molecular:558.7Zebularine
CAS:<p>Zebularine (4-Deoxyuridine) is a DNA methylation inhibitor.</p>Fórmula:C9H12N2O5Pureza:99.04% - >99.99%Cor e Forma:SolidPeso molecular:228.2Soyasapogenol B
CAS:<p>Soyasapogenol B has anti-cancer, hypocholesterolemic, anticomplementary, hepatoprotective effects, it inhibits proliferation of cultured Hep-G2.</p>Fórmula:C30H50O3Pureza:99.51% - 99.81%Cor e Forma:SolidPeso molecular:458.72Cryptotanshinone
CAS:<p>Cryptotanshinone: STAT3 inhibitor, IC50 4.6 μM; blocks STAT3 Tyr705 phosphorylation, minor effect on Ser727, no impact on STAT1/5.</p>Fórmula:C19H20O3Pureza:97.94% - ≥95%Cor e Forma:Orange Needle CrystalPeso molecular:296.36Idarubicin hydrochloride
CAS:<p>Idarubicin hydrochloride (Zavedos), a hydrochloride salt form of Idarubicin, is a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells ( IC50: 3.3 ng/mL).</p>Fórmula:C26H27NO9·HClPureza:98.91% - 99.96%Cor e Forma:SolidPeso molecular:533.95GSK2606414
CAS:<p>GSK2606414 is a cell-permeable and orally active protein kinase R-like endoplasmic reticulum kinase（PERK）inhibitor.Cost-effective and quality-assured.</p>Fórmula:C24H20F3N5OPureza:98% - >99.99%Cor e Forma:SolidPeso molecular:451.44Panobinostat
CAS:<p>Panobinostat (NVP-LBH589) is a broad-spectrum HDAC inhibitor (IC50=5 nM) with oral activity and non-selectivity.</p>Fórmula:C21H23N3O2Pureza:97.2% - 99.81%Cor e Forma:Yellow SolidPeso molecular:349.43Crizotinib
CAS:<p>Crizotinib (PF-02341066) is an ATP-competitive small-molecule tyrosine kinases inhibitor of c-MET (IC50: 8 nM) and ALK (IC50: 20 nM) receptor.</p>Fórmula:C21H22Cl2FN5OPureza:99% - 99.87%Cor e Forma:SolidPeso molecular:450.34SB 216763
CAS:<p>SB 216763 (SB216763) is an effective and specific GSK-3α/β inhibitor (IC50: 34.3 nM).</p>Fórmula:C19H12Cl2N2O2Pureza:98.9% - 99.13%Cor e Forma:SolidPeso molecular:371.22(+)-JQ-1
CAS:<p>(+)-JQ-1 (JQ1) is a BET bromine domain inhibitor that inhibits BRD4 (1/2) (IC50=77/33 nM) with specificity and reversibility.</p>Fórmula:C23H25ClN4O2SPureza:97.57% - ≥95%Cor e Forma:SolidPeso molecular:456.99Juglanin
CAS:<p>Juglanin is a JNK activator. Juglanin with inflammation and anti-tumor activities. It can induce apoptosis and autophagy on human breast cancer cells.</p>Fórmula:C20H18O10Pureza:98.8% - 99.33%Cor e Forma:SolidPeso molecular:418.35LYS01
CAS:<p>LYS01 free base is a new lysosomal autophagy inhibitor.</p>Fórmula:C23H23Cl2N5Pureza:98.28%Cor e Forma:SolidPeso molecular:440.37Meglutol
CAS:<p>Meglutol, a cholesterol and triglyceride reducing antilipemic, hinders key enzymes in cholesterol biosynthesis.</p>Fórmula:C6H10O5Pureza:99.73% - 99.94%Cor e Forma:SolidPeso molecular:162.14MRT68921 dihydrochloride
CAS:<p>MRT68921 dihydrochloride is a potent ULK1 and ULK2 inhibitor (IC50 of 2.9 nM and 1.1 nM, respectively).</p>Fórmula:C25H36Cl2N6OPureza:98.91% - 99.92%Cor e Forma:SolidPeso molecular:507.499Berberine hydrogen sulphate
CAS:<p>Berberine hydrogen sulphate, a plant alkaloid, has broad antimicrobial effects on bacteria, fungi, and protozoa.</p>Fórmula:C20H19NO8SPureza:99% - 99.79%Cor e Forma:Yellow Crystals Off-White To Yellow PowderPeso molecular:433.434,4'-Dimethoxychalcone
CAS:<p>4,4'-Dimethoxychalcone (4,4-Dimethoxychalcone) is a natural product.</p>Fórmula:C17H16O3Pureza:99.57%Cor e Forma:SolidPeso molecular:268.31Hoechst 33342 trihydrochloride
CAS:<p>Hoechst 33342 trihydrochloride (bisBenzimide H 33342 trihydrochloride;HOE 33342 trihydrochloride) is a membrane permeant DNA stain with blue fluorescence.</p>Fórmula:C27H31Cl3N6OPureza:98.73% - ≥98%Cor e Forma:SolidPeso molecular:561.93Ixazomib citrate
CAS:<p>Ixazomib citrate (MLN9708), a prodrug of Ixazomib (MMLN-2238), is an oral 2nd-gen proteasome inhibitor with anti-cancer potential (IC50: 3.4 nM).</p>Fórmula:C20H23BCl2N2O9Pureza:98.37% - >99.99%Cor e Forma:SolidPeso molecular:517.12MG-132
CAS:<p>MG-132 (Z-Leu-Leu-Leu-al) is a 26S proteasome inhibitor, cell-permeable and reversible,an autophagy activator, induces apoptosis. High-Quality, Low-Cost!</p>Fórmula:C26H41N3O5Pureza:95% - 99.99%Cor e Forma:White To Off-White PowderPeso molecular:475.62Vps34-IN-1
CAS:<p>Vps34-IN-1: potent, selective Vps34 inhibitor, 25 nM IC50, spares class I/II PI3Ks.</p>Fórmula:C21H24ClN7OPureza:97.04%Cor e Forma:SolidPeso molecular:425.91SAR405
CAS:<p>SAR-405 inhibits PIK3C3/Vps34 (IC50: 1.2 nM, Kd: 1.5 nM), blocks autophagy, and enhances MTOR inhibitor effects on cancer cells.</p>Fórmula:C19H21ClF3N5O2Pureza:99.42% - 99.79%Cor e Forma:SolidPeso molecular:443.85Galangin
CAS:<p>Galangin (Norizalpinin) is an agonist/antagonist of the arylhydrocarbon receptor, and also shows inhibition of CYP1A1 activity.</p>Fórmula:C15H10O5Pureza:98.24% - 99.93%Cor e Forma:Yellowish Needle-Like CrystalPeso molecular:270.24CZC-25146
CAS:<p>CZC-25146, a stable LRRK2 inhibitor, IC50: 4.76 nM (wild-type), 6.87 nM (G2019S).</p>Fórmula:C22H25FN6O4SPureza:97.68%Cor e Forma:SolidPeso molecular:488.54AZ304
CAS:<p>AZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits BRAF (WT), BRAF (V600E), and wild type CRAF (IC50s: 79/38/68 nM).</p>Fórmula:C27H25N5O2Pureza:99.82%Cor e Forma:SolidPeso molecular:451.52KB-R7943 mesylate
CAS:<p>KB-R7943 mesylate is a widely used inhibitor of the reverse Na+/Ca2+ exchanger (NCXrev) with IC50 of 5.7±2.1 μM.</p>Fórmula:C17H21N3O6S2Pureza:99.88% - ≥95%Cor e Forma:SolidPeso molecular:427.5Briciclib
CAS:<p>Briciclib (ON 014185) is a small molecule that suppresses cyclin D1 accumulation in Y cells.</p>Fórmula:C19H23O10PSPureza:98% - 99.84%Cor e Forma:SolidPeso molecular:474.42JNJ-42165279
CAS:<p>JNJ-42165279 selectively inactivates FAAH without notably affecting other enzymes, ion channels, receptors, or CYPs/hERG at 10 μM.</p>Fórmula:C18H17ClF2N4O3Pureza:99.67% - 99.88%Cor e Forma:SolidPeso molecular:410.8Hoechst 33342
CAS:<p>Hoechst 33342 (bisBenzimide H 33342) is a benzimidazole fluorescent dye and a cell-permeable fluorescent DNA dye. High-Quality, Low-Cost!</p>Fórmula:C27H28N6OPureza:98.12% - 99.75%Cor e Forma:Yellow-Green PowderPeso molecular:452.55Brevilin A
CAS:<p>Brevilin A, a sesquiterpene from Centipeda minima, hinders JAK and blocks STAT3 (IC50=10.6μM), inducing apoptosis and autophagy in cancer cells.</p>Fórmula:C20H26O5Pureza:99.97% - >99.99%Cor e Forma:SolidPeso molecular:346.42Ponatinib
CAS:<p>Ponatinib (AP24534) is an orally available, multitargeted kinase inhibitor (IC50s: 0.37/1.1/1.5/2.2/5.4 nM for Abl, PDGFRα, VEGFR2, FGFR1, and Src, respectively</p>Fórmula:C29H27F3N6OPureza:98% - 99.60%Cor e Forma:SolidPeso molecular:532.56Actein
CAS:<p>Actein stimulates bone formation, counters osteoporosis and oxidative damage, and may treat lipid disorders and cancer, inhibiting breast cancer cell growth.</p>Fórmula:C37H56O11Pureza:≥98%Cor e Forma:Brown PowderPeso molecular:676.83Tempol
CAS:<p>Tempol (Tanol) is a superoxide scavenger. It has anti-inflammatory, neuroprotective and analgesic effects.</p>Fórmula:C9H18NO2Pureza:97% - 99.74%Cor e Forma:4-Hydroxy-Tempo Appears As Orange Flakes Solid FlakesPeso molecular:172.25N-Benzyllinolenamide
CAS:<p>N-Benzyllinolenamide is a natural product. It is an inhibitor of fatty acid amide hydrolase (FAAH, IC50 of 41.8 μM).</p>Fórmula:C25H37NOPureza:98.7% - 99.92%Cor e Forma:SolidPeso molecular:367.57Peretinoin
CAS:<p>Peretinoin (NIK333) is an oral acyclic retinoid with a vitamin A-like structure that targets retinoid nuclear receptors such as RXR and RAR.</p>Fórmula:C20H30O2Pureza:97.23%Cor e Forma:SolidPeso molecular:302.45LC3-mHTT-IN-AN2
CAS:<p>LC3-mHTT-IN-AN2 (5,7-Dihydroxy-4-phenylcoumarin) is found in the plant Passiflora serratodigitata with the antibacterial activity.</p>Fórmula:C15H10O4Pureza:98.82% - ≥98%Cor e Forma:SolidPeso molecular:254.24Rabusertib
CAS:<p>Rabusertib (IC-83) is a chk1 inhibitor in trials for various cancers, including pancreatic and non-small cell lung cancer.</p>Fórmula:C18H22BrN5O3Pureza:98.86% - 99.87%Cor e Forma:SolidPeso molecular:436.3SN-38
CAS:<p>SN-38 (NK012) is the active metabolite of Irinotecan, a DNA topoisomerase I (Topo I) inhibitor, which inhibits DNA and RNA synthesis (IC50=0.077/1.3 μM).</p>Fórmula:C22H20N2O5Pureza:98% - 99.97%Cor e Forma:Light-Yellow SolidPeso molecular:392.4Ethyl 3,4-dihydroxybenzoate
CAS:<p>Ethyl 3,4-dihydroxybenzoate (EDHB): a prolyl hydroxylase inhibitor attenuates acute hypobaric hypoxia mediated vascular leakage in brain.</p>Fórmula:C9H10O4Pureza:99.88%Cor e Forma:White Crystal Or PowderPeso molecular:182.17AS1842856
CAS:<p>AS1842856 is a Foxo1 inhibitor that blocks the transcriptional activity of Foxo1. AS1842856 has autophagy inhibitory activity. Cost-effective and quality-assured.</p>Fórmula:C18H22FN3O3Pureza:99.36% - >99.99%Cor e Forma:SolidPeso molecular:347.38DMH-1
CAS:<p>DMH-1 is a BMP inhibitor that inhibits ALK1, ALK2, ALK3 and ALK6. DMH-1 promotes pluripotent stem cell differentiation. Cost-effective and quality-assured.</p>Fórmula:C24H20N4OPureza:98% - 99.92%Cor e Forma:SolidPeso molecular:380.44SP600125
CAS:<p>SP600125 (JNK Inhibitor II) is a JNK inhibitor that inhibits JNK1, JNK2, and JNK3 (IC50=40/40/90 nM) with oral potency, reversibility, and ATP-competitive</p>Fórmula:C14H8N2OPureza:97.63% - 99.82%Cor e Forma:SolidPeso molecular:220.23Pexmetinib
CAS:<p>Pexmetinib (ARRY-614) is an orally bioavailable dual p38 MAPK/Tie-2 inhibitor.Cost-effective and quality-assured.</p>Fórmula:C31H33FN6O3Pureza:99.07% - 99.66%Cor e Forma:SolidPeso molecular:556.63Vps34-IN-4
CAS:<p>VPS34 inhibitor 1 (Compound 19, PIK-III analogue) (PIK-III analogue) is a potent and selective inhibitor of VPS34( IC50 : 15 nM)</p>Fórmula:C21H25N7OPureza:98.6%Cor e Forma:SolidPeso molecular:391.473BDO
CAS:<p>3BDO is a new mTOR activator. 3BDO inhibits autophagy.</p>Fórmula:C18H17NO5Pureza:97.76%Cor e Forma:SolidPeso molecular:327.33XCT790
CAS:<p>XCT790 is a potent, selective and inverse agonist of estrogen-related receptor alpha(ERRα).</p>Fórmula:C23H13F9N4O3SPureza:99% - 99.61%Cor e Forma:SolidPeso molecular:596.4220-DEOXYINGENOL
CAS:<p>20-DEOXYINGENOL is a natual product.</p>Fórmula:C20H28O4Pureza:99.98% - ≥95%Cor e Forma:SolidPeso molecular:332.43Pseudolaric Acid B
CAS:<p>Pseudolaric acid B, a natural diterpenoid compound, is isolated from Pseudolarix kaempferi.</p>Fórmula:C23H28O8Pureza:98.91% - 99.84%Cor e Forma:SolidPeso molecular:432.46U0126
CAS:<p>U0126, an effective and selective non-competitive inhibitor of MAP kinase, inhibits MEK-1 and MEK-2 with IC50 values of 0.07 and 0.06 μM respectively.</p>Fórmula:C18H16N6S2Pureza:99.61%Cor e Forma:White SolidPeso molecular:380.49Torin 1
CAS:<p>Torin 1 is an effective inhibitor of mTORC1/2 with (IC50: 2 nM/10 nM); has 1000-fold selectivity for mTOR than PI3K.</p>Fórmula:C35H28F3N5O2Pureza:98.3% - 99.33%Cor e Forma:SolidPeso molecular:607.62Clinofibrate
CAS:<p>Clinofibrate lowers lipids, blocks HMGCR (IC50: 0.47 mM), and controls cholesterol/triacylglycerides.</p>Fórmula:C28H36O6Pureza:>99.99%Cor e Forma:White Crystalline PowderPeso molecular:468.58Alginic acid
CAS:<p>Alginic acid, a polysaccharide from brown seaweed, has anti-anaphylactic and anti-inflammatory properties and is used in food industry.</p>Fórmula:C14H22O13Pureza:≥98%Cor e Forma:SolidPeso molecular:398.317Oleanolic Acid
CAS:<p>Oleanolic Acid (Caryophyllin) is a natural compound with anti-tumor activities, which are widely distributed in plants.</p>Fórmula:C30H48O3Pureza:97.04% - 98.51%Cor e Forma:SolidPeso molecular:456.7Tetrahydrocurcumin
CAS:<p>Tetrahydrocurcumin (HZIV 81-2), a major metabolite of curcumin, has strong antioxidant and cardioprotective properties.</p>Fórmula:C21H24O6Pureza:97.81% - 98.82%Cor e Forma:Solid PowderPeso molecular:372.41Salbutamol hemisulfate
CAS:<p>Salbutamol hemisulfate (Albuterol Sulfate) is a short-acting β2-adrenergic receptor agonist with an IC50 of 8.93 μM.</p>Fórmula:C13H21NO3H2O4SPureza:99.35%Cor e Forma:White Or Almost White Odourless PowderPeso molecular:576.70JZL195
CAS:<p>JZL195 is a selective and efficacious dual FAAH/MAGL inhibitor.</p>Fórmula:C24H23N3O5Pureza:99.81%Cor e Forma:SolidPeso molecular:433.46Acumapimod
CAS:<p>Acumapimod (BCT-197) is an orally active inhibitor of p38α MAPK (IC50 <1 μM).</p>Fórmula:C22H19N5O2Pureza:≥95%Cor e Forma:SolidPeso molecular:385.42Lithocholic acid
CAS:<p>Lithocholic acid (3α-Hydroxy-5β-cholanic acid) is a toxic secondary bile acid, They were FXR antagonists (IC50=0.7, 1.4 μM). High-Quality, Low-Cost!</p>Fórmula:C24H40O3Pureza:99.69% - 99.93%Cor e Forma:Hexagonal Leaflets From Alc Prisms From Acetic Acid Powder (Ntp 1992)Peso molecular:376.57Scutellarein
CAS:<p>Scutellarein (6-Hydroxyapigenin) reduces inflammatory responses by inhibiting Src kinase activity.</p>Fórmula:C15H10O6Pureza:98.02% - 99.63%Cor e Forma:SolidPeso molecular:286.24Vancomycin
CAS:<p>Vancomycin is a glycopeptide antibiotic that exerts its antimicrobial activity by altering the permeability of cell membranes and selectively inhibiting</p>Fórmula:C66H75Cl2N9O24Pureza:98.76% - 99.35%Cor e Forma:Almost White PowderPeso molecular:1449.25URB-597
CAS:<p>URB-597 (FAAH Inhibitor II) is an effective, orally bioavailable FAAH inhibitor (IC50: 4.6 nM), and no effect on other cannabinoid-related targets.</p>Fórmula:C20H22N2O3Pureza:97.20% - 98.24%Cor e Forma:SolidPeso molecular:338.4Tropifexor
CAS:<p>Tropifexor (LJN452) is a novel and highly potent agonist of FXR with an EC50 of 0.2 nM.</p>Fórmula:C29H25F4N3O5SPureza:99.3% - 99.85%Cor e Forma:SolidPeso molecular:603.58Obeticholic Acid
CAS:<p>Obeticholic Acid (6-ECDCA, INT-747) is a high-affinity, semisynthetic, bile acid-derived FXR agonist.Cost-effective and quality-assured.</p>Fórmula:C26H44O4Pureza:99.88% - 99.97%Cor e Forma:SolidPeso molecular:420.63TG101209
CAS:<p>TG101209 is a selective JAK2 inhibitor with IC50 of 6 nM.</p>Fórmula:C26H35N7O2SPureza:99% - >99.99%Cor e Forma:SolidPeso molecular:509.67Pifithrin-μ
CAS:<p>Pifithrin-μ (NSC-303580) is an inhibitor of p53 and HSP70, with neuroprotective and antitumor activity.</p>Fórmula:C8H7NO2SPureza:99.33% - 99.79%Cor e Forma:SolidPeso molecular:181.21Valinomycin
CAS:<p>Valinomycin (NSC-122023) is a cyclic depsipeptide antibiotic and a potassium-specific ionophore.Valinomycin induces PINK1 activation and promotes Parkin</p>Fórmula:C54H90N6O18Pureza:95.37% - 97.16%Cor e Forma:White SolidPeso molecular:1111.32Eupatilin
CAS:<p>Eupatilin (NSC-122413), a flavone derived from Artemisia princepsPampanini, is a PPARα agonist, with pharmacological activity.</p>Fórmula:C18H16O7Pureza:98.53% - 99%Cor e Forma:SolidPeso molecular:344.32LYN-1604
CAS:<p>LYN-1604 is a novel activator of ULK1, inducing cell death involved in ATF3, RAD21, and caspase3, accompanied by autophagy and apoptosis.</p>Fórmula:C33H43Cl2N3O2Pureza:98%Cor e Forma:SolidPeso molecular:584.62SR9009
CAS:<p>SR9009, a REV-ERB agonist, modulates genes and circadian rhythms, reducing fat mass and improving metabolism in obese mice.</p>Fórmula:C20H24ClN3O4SPureza:99.94% - >99.99%Cor e Forma:SolidPeso molecular:437.94BC1618
CAS:<p>BC1618 (2-Propanol, 1-[bis(phenylmethyl)amino]-3-[4-(trifluoromethyl)phenoxy]-) is an orally active Fbxo48 inhibitor that stimulates Ampk-dependent signaling.</p>Fórmula:C24H24F3NO2Pureza:99.95%Cor e Forma:SolidPeso molecular:415.45
