Autofagia
Os inibidores da autofagia têm como alvo o processo celular de autofagia, que envolve a degradação e reciclagem de componentes celulares através dos lisossomas. A autofagia é um mecanismo crítico para a manutenção da homeostase celular, mas sua desregulação está implicada em várias doenças, incluindo câncer, neurodegeneração e infecções. Os inibidores da autofagia podem bloquear este processo, tornando-os ferramentas valiosas para estudar o papel da autofagia nas doenças e desenvolver estratégias terapêuticas. Na CymitQuimica, oferecemos inibidores da autofagia para apoiar sua pesquisa em biologia celular, oncologia e doenças neurodegenerativas.
Foram encontrados 1424 produtos de "Autofagia"
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Lapatinib Ditosylate
CAS:<p>Lapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).</p>Fórmula:C29H26ClFN4O4S·2C7H8O3SPureza:99.41%Cor e Forma:Yellow SolidPeso molecular:925.46Fluvastatin sodium
CAS:<p>Fluvastatin sodium (Fluvastatin sodium salt), a competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase (HMGCR), is a commonly used cholesterol</p>Fórmula:C24H25FNNaO4Pureza:98.54% - 99.56%Cor e Forma:Light Yellow Solid PowderPeso molecular:433.45Lapatinib ditosylate monohydrate
CAS:<p>Lapatinib ditosylate monohydrate: a drug for advanced breast cancer; may cause liver issues.</p>Fórmula:C29H26ClFN4O4S·2(C7H8O3S)·H2OPureza:98% - 99.41%Cor e Forma:Colourless To Light-Yellow CrystalPeso molecular:943.47Erlotinib
CAS:<p>Erlotinib (NSC-718781) is an EGFR inhibitor (IC50: 2 nM). It is used for the treatment of non-small cell lung cancer.</p>Fórmula:C22H23N3O4Pureza:98.19% - 99.98%Cor e Forma:White To Off-White PowderPeso molecular:393.44Dexamethasone acetate
CAS:<p>Dexamethasone acetate (NSC 39471) is a potent anti-inflammatory steroid, blocks NF-kB, and lacks salt-retention.</p>Fórmula:C24H31FO6Pureza:99.22% - 99.65%Cor e Forma:White Or Almost White Crystalline PowderPeso molecular:434.50AZD7624
CAS:<p>AZD7624 is an p38 inhibitor. It has potent anti-inflammatory activity.</p>Fórmula:C27H30FN5O3Pureza:98.82%Cor e Forma:SolidPeso molecular:491.56Spironolactone
CAS:<p>Spironolactone (SC9420) is an Aldosterone Antagonist. The mechanism of action of spironolactone is as an Aldosterone Antagonist.</p>Fórmula:C24H32O4SPureza:99.87%Cor e Forma:White PowderPeso molecular:416.57Chenodeoxycholic acid
CAS:<p>Chenodeoxycholic acid (CDCA) is a bile acid that inhibits 11β-HSD2 with an IC50 value of 22 mM. High-Quality, Low-Cost!</p>Fórmula:C24H40O4Pureza:99.70% - 99.93%Cor e Forma:White - Almost White Solid PowderPeso molecular:392.57Itraconazole
CAS:<p>Itraconazole (R51211) is a triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes required for ERGOSTEROL synthesis.</p>Fórmula:C35H38Cl2N8O4Pureza:98% - 99.90%Cor e Forma:Off-White Crystalline SolidPeso molecular:705.63Vancomycin hydrochloride
CAS:<p>Vancomycin hydrochloride (Vancomycin HCl) targets peptidoglycan in bacterial cell wall synthesis. High-Quality, Low-Cost!</p>Fórmula:C66H76Cl3N9O24Pureza:97.20% - 99.19%Cor e Forma:Off White PowderPeso molecular:1485.71Reserpine
CAS:<p>Reserpine, an alkaloid from Rauwolfia roots, depletes neurotransmitters, used in treating hypertension and psychosis, but side effects restrict use.</p>Fórmula:C33H40N2O9Pureza:98.85% - 99.81%Cor e Forma:White Or Pale Buff To Slightly Yellowish Powder With A Bitter Taste (Ntp 1992)Peso molecular:608.68ZX-29
CAS:<p>ZX-29: Strong ALK inhibitor; IC50 - ALK 2.1 nM, L1196M 1.3 nM, G1202R 3.9 nM; triggers autophagy; anti-cancer.</p>Fórmula:C23H28ClN7O3SPureza:98.32%Cor e Forma:SolidPeso molecular:518.03LG-100064
CAS:<p>LG-100064 is an agonist of retinoid-X-receptor (RXR)(EC50s of 330 nM, 200 nM, and 260 nM for RXRα, RXRβ and RXRγ)</p>Fórmula:C23H26O3Pureza:98.65%Cor e Forma:SolidPeso molecular:350.45Pyrazinamide
CAS:<p>Pyrazinamide (Pyrazinecarboxamide), an antimycobacterial, is utilized therapeutically as an antitubercular agent, which is a synthetic pyrazinoic acid amide</p>Fórmula:C5H5N3OPureza:99.71% - 99.9%Cor e Forma:Crystals Physical Description White Powder Sublimes From 318°F (Ntp 1992)Peso molecular:123.11Raloxifene hydrochloride
CAS:<p>Raloxifene HCl treats postmenopausal osteoporosis, acts as estrogen on bone/cholesterol, and blocks it in breast/uterus.</p>Fórmula:C28H28ClNO4SPureza:98% - 99.97%Cor e Forma:Light Yellow SolidPeso molecular:510.044Lomustine
CAS:<p>Lomustine (NSC-79037) is an alkylating agent of value against both hematologic malignancies and solid tumors.</p>Fórmula:C9H16ClN3O2Pureza:98.36% - 99.44%Cor e Forma:Solid SolidPeso molecular:233.7Crustecdysone
CAS:<p>Crustecdysone (Hydroxyecdysone) is a steroid hormone that regulates the processes of molting or ecdysis in insects.</p>Fórmula:C27H44O7Pureza:99.06% - 99.67%Cor e Forma:Canary Yellow Fine PowderPeso molecular:480.63Matrine
CAS:<p>Matrine (Vegard), an alkaloid isolated from the Sophora genus, acts as a kappa opioid receptor agonist.</p>Fórmula:C15H24N2OPureza:97.16% - >99.99%Cor e Forma:SolidPeso molecular:248.36Nicardipine hydrochloride
CAS:<p>Nicardipine hydrochloride is a potent calcium channel blocker used to dilate cerebral and coronary vessels.</p>Fórmula:C26H30ClN3O6Pureza:99.58% - 99.89%Cor e Forma:Yellow SolidPeso molecular:515.99Sorafenib tosylate
CAS:<p>Sorafenib tosylate (Bay 43-9006) is a potent multikinase inhibitor (IC50s: 6/20/22 nM for Raf-1/VEGFR-3/B-Raf).</p>Fórmula:C21H16ClF3N4O3·C7H8O3SPureza:99.24% - 99.94%Cor e Forma:White To Off-White Crystalline PowderPeso molecular:637.03
