Receptor opioide
Os receptores opioides são um grupo de receptores acoplados à proteína G que mediam os efeitos dos opioides endógenos e exógenos. Estes receptores desempenham um papel central na modulação da dor, regulação do humor e comportamentos aditivos. Agonistas e antagonistas dos receptores opioides são amplamente utilizados no manejo da dor e tratamento de dependências, bem como em pesquisas sobre distúrbios neurológicos e psiquiátricos. Na CymitQuimica, oferecemos uma seleção abrangente de moduladores de receptores opioides de alta qualidade para apoiar sua pesquisa em neurobiologia, manejo da dor e terapia de dependência.
Foram encontrados 326 produtos de "Receptor opioide"
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Boc-ypgflt(O-tbu)
CAS:Boc-ypgflt(O-tbu) is a delta-receptor-selective opioid antagonist.Fórmula:C44H64N6O11Cor e Forma:SolidPeso molecular:853.01Ro 64-6198
CAS:Ro 64-6198: Nonpeptide, selective NOP agonist, high brain uptake, EC50=25.6 nM, 100x NOP>opioid affinity.Fórmula:C26H31N3OPureza:98%Cor e Forma:SolidPeso molecular:401.54Nocistatin
CAS:Nocistatin, a neuropeptide, blocks Nociceptin effects and inhibits 5-HT release, acting on an opioid-related receptor.Fórmula:C32H56N10O12Cor e Forma:SolidPeso molecular:772.85Cebranopadol hemicitrate
CAS:Cebranopadol hemicitrate is a NOP and opioid receptor agonist that targets human NOP, MOP, KOP, and δ-opioid peptide (DOP) receptors, with Ki/EC50 values of 0.9 nM/13 nM, 0.7 nM/1.2 nM, 2.6 nM/17 nM, and 18 nM/110 nM, respectively. It is used in studies of acute and chronic pain.Cor e Forma:SolidAc-RYYRWK-NH2
CAS:<p>Selective NOP receptor partial agonist peptide; Ki=0.71 nM; >4000 nM for μ, δ, κ receptors; boosts food intake in vivo.</p>Fórmula:C49H69N15O9Pureza:98%Cor e Forma:SolidPeso molecular:1012.17[Met5]-Enkephalin, amide
CAS:[Met5]-Enkephalin, amide activates δ and ζ opioid receptors; has multiple forms and varying plasma levels.Fórmula:C27H36N6O6SPureza:98%Cor e Forma:SolidPeso molecular:572.68[Nphe1]Nociceptin(1-13)NH2
CAS:<p>Competitive nociceptin receptor antagonist with pKi=8.4; no agonist activity; blocks nociceptin effects in vitro/in vivo.</p>Fórmula:C61H100N22O15Pureza:98%Cor e Forma:SolidPeso molecular:1381.6UFP-101
CAS:<p>Strong, selective NOP receptor antagonist with pKi=10.24; >3000x selectivity over δ, μ, κ receptors; blocks nociceptin effects.</p>Fórmula:C82H138N32O21Pureza:98%Cor e Forma:SolidPeso molecular:1908.19U-54494A hydrochloride
CAS:U-54494A hydrochloride is a benzamide derivative related to kappa opioid receptor agonists. U-54494A hydrochloride has anticonvulsant activity.Fórmula:C18H25Cl3N2OCor e Forma:SolidPeso molecular:391.76ICI 174,864
CAS:<p>Selective δ opioid antagonist. Exhibits partial agonist in vitro activity at δ receptors at high concentrations.</p>Fórmula:C38H53N5O7Pureza:98%Cor e Forma:White SolidPeso molecular:691.87SNC 80
CAS:SNC 80, a non-peptide δ-opioid agonist (Ki=1.78 nM, IC50=2.73 nM), also targets μ-δ heteromers (EC50=52.8 nM), with analgesic and antidepressant potential.Fórmula:C28H39N3O2Pureza:99.65%Cor e Forma:SolidPeso molecular:449.63Herkinorin
CAS:Herkinorin: μ-opioid agonist with 100x μ-affinity, 50x less κ-affinity than Salvinorin A, from Salvia divinorum. Semi-synthetic from Salvinorin B.Fórmula:C28H30O8Cor e Forma:SolidPeso molecular:494.53β-Endorphin, equine
CAS:Endorphin Beta is A substance produced in the brain, especially in the pituitary gland, Endorphin Beta blocks the sensation of pain.Fórmula:C154H248N42O44SPureza:98%Cor e Forma:SolidPeso molecular:3423.94CTOP
CAS:Potent μ-receptor antagonist, Ki=0.96nM, ineffective at δ (>10,000nM). Alters behavior in vivo, boosts K+ currents in rat neurons in vitro, μ-independent.Fórmula:C50H67N11O11S2Pureza:98%Cor e Forma:SolidPeso molecular:1062.28Orphanin FQ(1-11)
CAS:<p>Nociceptin peptide fragment (1-11) with potent ORL1/KOR-3 receptor agonism (Ki = 55 nM), no opioid receptor affinity, and analgesic in mice.</p>Fórmula:C49H75N15O14Pureza:98%Cor e Forma:SolidPeso molecular:1098.2Neuropeptide AF (human)
CAS:Neuropeptide AF (93-110), Human is an endogenous antiopioid peptide.Fórmula:C90H132N26O25Pureza:98%Cor e Forma:SolidPeso molecular:1978.17CTAP
CAS:Potent μ opioid antagonist, IC50 3.5 nM, 1200x selectivity over δ and somatostatin, brain-penetrant, active in vivo.Fórmula:C51H69N13O11S2Pureza:98%Cor e Forma:White Solid/PowderPeso molecular:1104.32Dermorphin
CAS:<p>Dermorphin is agonist of μ-opioid receptor (MOR) agonist.</p>Fórmula:C40H50N8O10Pureza:98.82%Cor e Forma:SolidPeso molecular:802.87N-Desmethyl Loperamide
CAS:N-Desmethyl Loperamide is the major metabolite of loperamide. It is also used as the precusor for radiolabelled loperamide.Fórmula:C28H31ClN2O2Cor e Forma:SolidPeso molecular:463.01Helianorphin-19
<p>Helianorphin-19: Potent KOR agonist (Ki=25 nM; EC50=45 nM), 200x selective over μ/δ receptors, effective in mouse pain model, non-sedative.</p>Cor e Forma:Liquid
![[Met5]-Enkephalin, amide](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTP1255.webp&w=3840&q=75)
![[Nphe1]Nociceptin(1-13)NH2](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FTM%2Fthumb-webp%2FTP1987.webp&w=3840&q=75)
