Receptor de adenosina
Os receptores de adenosina são uma classe de GPCRs que respondem ao nucleosídeo endógeno adenosina. Esses receptores estão envolvidos na regulação de vários processos fisiológicos, incluindo função cardiovascular, ciclos de sono-vigília e respostas imunes. Moduladores de receptores de adenosina têm potencial terapêutico no tratamento de condições como arritmias cardíacas, inflamação e doenças neurodegenerativas. Na CymitQuimica, oferecemos uma seleção de moduladores de receptores de adenosina de alta qualidade para apoiar sua pesquisa em biologia cardiovascular, neurociência e imunologia.
Foram encontrados 249 produtos de "Receptor de adenosina"
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Adenosine receptor antagonist 2
CAS:Adenosine receptor antagonist 2 is an orally active A2a (IC50: 1 nM), A2b (IC50: 3 nM) adenosine receptor antagonist that exhibits antitumour effects.Fórmula:C23H21FN8OCor e Forma:SolidPeso molecular:444.46CAY10498
CAS:A3 AR antagonist CAY10498, with Ki of 37 nM, is 60-200x selective over A1/A2A receptors; no dedifferentiation effects shown.Fórmula:C18H20N6Cor e Forma:SolidPeso molecular:320.39VUF8507
CAS:Vuf8507 is an allosteric regulator of adenosine receptor.Fórmula:C21H15N3OCor e Forma:SolidPeso molecular:325.36PD 81723
CAS:Allosteric potentiator at the adenosine A1 receptorFórmula:C14H12F3NOSPureza:98%Cor e Forma:SolidPeso molecular:299.31Sipagladenant
CAS:Sipagladenant: oral inverse agonist for A2A adenosine receptor, may aid frontal lobe dysfunction research.Fórmula:C20H19N3O4SCor e Forma:SolidPeso molecular:397.45SCH-202676 HBr
CAS:SCH-202676 HBr is an allosteric agonist. It also an GPCR antagonist.Fórmula:C15H13N3SPureza:98%Cor e Forma:SolidPeso molecular:267.35A3AR antagonist 2
CAS:A3AR antagonist 2 is a potent antagonist of the human A3 adenosine receptor, exhibiting a Ki value of 4.54 nM.Fórmula:C22H16N6O3Cor e Forma:SolidPeso molecular:412.4TH-162
CAS:TH-162 (R)-PIA is an A1 adenosine receptor agonist with ~100× higher affinity than its (+)-isomer.Fórmula:C19H23N5O4Cor e Forma:SolidPeso molecular:385.42PQ-69
CAS:PQ-69 is a selective adenosine A1 receptor antagonist with inverse agonist activity.Fórmula:C20H19FN4OCor e Forma:SolidPeso molecular:350.39MRS 1523
CAS:MRS 1523: selective adenosine A3 antagonist, Ki 18.9/113 nM (human/rat), blocks N-type Ca channels & inhibits action potentials in rat DRG neurons.Fórmula:C23H29NO3SPureza:98%Cor e Forma:SolidPeso molecular:399.55Inupadenant
CAS:Inupadenant is an orally active, highly selective A2A receptor antagonist. Inupadenant is not brain-penetrant. Inupadenant has potent anti-tumor activity[1].Fórmula:C25H26F2N8O4S2Cor e Forma:SolidPeso molecular:604.65CAY10680
CAS:CAY10680 inhibits MAO-B (IC50=34.9 nM) & A2A receptors (Ki=39.5 nM), sparing other adenosine types & MAO-A, may treat Parkinson's.Fórmula:C18H16N2O2SCor e Forma:SolidPeso molecular:324.4FR-194921
CAS:FR-194921: potent oral adenosine A1 antagonist, improves cognition, reduces anxiety, similar efficacy in humans, rats, mice.Fórmula:C23H23N5OCor e Forma:SolidPeso molecular:385.46CVT-2759
CAS:CVT-2759, potential A(1)-ADOR partial agonist, could slow ventricular rate without severe cardiac side effects.Fórmula:C17H24N6O6Cor e Forma:SolidPeso molecular:408.41Adenosine receptor inhibitor 2
CAS:Compound 14b is a potent AR inhibitor with dual affinity, stronger for A1 (Ki = 52.2 nM) than A2A (Ki = 167 nM) ARs.Fórmula:C17H20BrN5O2Cor e Forma:SolidPeso molecular:406.28Acefylline piperazine
CAS:Acefylline piperazine, a less toxic theophylline derivative, treats asthma and bronchitis by bronchodilation, stimulating respiration and CNS.Fórmula:C9H10N4O4·xC4H10N2Cor e Forma:SolidPeso molecular:562.54JNJ-40255293
CAS:JNJ-40255293 is an antagonist of adenosine A2A/A1.Fórmula:C23H22N4O3Pureza:98%Cor e Forma:SolidPeso molecular:402.45AK-IN-1
CAS:AK-IN-1: competitive adenosine inhibitor, not ATP; inhibits AK 86-89% at 2-10 µM; promising for ischaemia, inflammation, seizure research.Fórmula:C22H21N3O4Cor e Forma:SolidPeso molecular:391.42ATL-801
CAS:ATL-801 is anselective antagonist of A2B receptor with herapeutic activity for colitis.Fórmula:C24H25N7O3Cor e Forma:SolidPeso molecular:459.5Kira8 Hydrochloride
CAS:Kira8 Hydrochloride is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α RNase activity with an IC50 of 5.9 nM.Fórmula:C31H30Cl2N6O3SPureza:98%Cor e Forma:SolidPeso molecular:637.58
