Síntese de DNA/RNA
Os inibidores da síntese de DNA e RNA são compostos que interferem nos processos de replicação e transcrição nas células, impedindo a produção de material genético essencial. Esses inibidores podem atingir várias enzimas e proteínas envolvidas na síntese de ácidos nucleicos, tornando-os ferramentas valiosas para estudar os mecanismos de replicação, transcrição e tradução. Eles também são usados no desenvolvimento de tratamentos para infecções e câncer. Na CymitQuimica, oferecemos uma ampla gama de inibidores da síntese de DNA/RNA para apoiar sua pesquisa em biologia molecular, virologia e desenvolvimento terapêutico.
Foram encontrados 793 produtos de "Síntese de DNA/RNA"
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Dasabuvir
CAS:Dasabuvir (ABT-333) blocks HCV replication by inhibiting the essential NS5B RNA polymerase.Fórmula:C26H27N3O5SPureza:99.54% - 99.62%Cor e Forma:SolidPeso molecular:493.57TH5487
CAS:TH5487 is an potent inhibitor of 8-oxoguanine DNA glycosylase 1 (OGG1)( IC50 of 342 nM)Fórmula:C19H18BrIN4O2Pureza:98.38% - 98.73%Cor e Forma:SolidPeso molecular:541.18Ref: TM-T8119
1mg48,00€2mg63,00€5mg94,00€10mg160,00€25mg304,00€50mg550,00€100mg792,00€500mg1.605,00€1mL*10mM (DMSO)111,00€3-Hydroxy-2-methylpyridine
CAS:3-Hydroxy-2-methylpyridine could as a promising molecular scaffold for the future development of novel fibrillization inhibitors.Fórmula:C6H7NOPureza:98.96% - 99.03%Cor e Forma:Beige-Brown PowderPeso molecular:109.131,4-Anthraquinone
CAS:1,4-Anthraquinone: anticancer, hinders nucleoside transport, inhibits synthesis, fragments DNA, curbs L1210 cell growth; aids HPLC analysis of NAC, CAP.Fórmula:C14H8O2Pureza:95.96% - 97.01%Cor e Forma:Orange Brown SolidPeso molecular:208.21HAMNO
CAS:HAMNO (NSC-111847) is a protein interaction inhibitor of replication protein A (RPA).Fórmula:C17H13NO2Pureza:99.96%Cor e Forma:SolidPeso molecular:263.29Tempo
CAS:Tempo (2,2,6,6-Tetramethylpiperidinooxy) has a wide range of applications including use as a free radical scavenger, a reagent in organic synthesis and as aFórmula:C9H18NOPureza:98.35%Cor e Forma:Orange Crystals Or PowderPeso molecular:156.25BMH-21
CAS:BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX.Fórmula:C21H20N4O2Pureza:99.47% - 99.84%Cor e Forma:SolidPeso molecular:360.41TH287
CAS:<p>TH287 is a potent inhibitor of MTH1 (NUDT1), less potent for MTH2, NUDT5, NUDT12, NUDT14, and NUDT16.</p>Fórmula:C11H10Cl2N4Pureza:97.73% - 99%Cor e Forma:SolidPeso molecular:269.13Adenine hydrochloride
CAS:<p>Adenine hydrochloride (6-Aminopurine hydrochloride) is a hydrochloride salt form of adenine which is a nucleobase with a variety of roles in biochemistry.</p>Fórmula:C5H5N5·HClPureza:98.86%Cor e Forma:White To Light Yellow Crystal PowderPeso molecular:171.59COH29
CAS:COH29 is an oral RNR-blocking thiazole that may reduce DNA synthesis and promote apoptosis, with potential cancer-treating properties.Fórmula:C22H16N2O5SPureza:97.04% - 98.92%Cor e Forma:SolidPeso molecular:420.44Ref: TM-T3157
1mg37,00€2mg52,00€5mg79,00€10mg119,00€25mg188,00€50mg354,00€100mg588,00€200mg833,00€1mL*10mM (DMSO)87,00€Alovudine
CAS:3'-Fluoro-3'-deoxythymidine (3'-Deoxy-3'-fluorothymidine) is a marker of DNA synthesis,which is less susceptible to inflammatory changes than FDG.Fórmula:C10H13FN2O4Pureza:99.41%Cor e Forma:Less Solid Colourless SolidPeso molecular:244.22β-Boswellic acid
CAS:β-Boswellic acid (Beta-boswellic acid) and its derivatives (the major constituents of Boswellin) have anti-carcinogenic, anti-tumor, and anti-hyperlipidemicFórmula:C30H48O3Pureza:99.2% - 99.91%Cor e Forma:Off-White SolidPeso molecular:456.70Ref: TM-TN1097
1mg62,00€5mg144,00€10mg225,00€25mg383,00€50mg557,00€100mg787,00€1mL*10mM (DMSO)170,00€Chebulinic acid
CAS:Chebulinic acid is a potent inhibitor of M. tuberculosis DNA gyrase. It also can inhibit SMAD-3 phosphorylation and H+ K+-ATPase activity.Fórmula:C41H32O27Pureza:98.91% - 99.71%Cor e Forma:SolidPeso molecular:956.68Ref: TM-TQ0184
1mg70,00€5mg154,00€10mg215,00€25mg432,00€50mg628,00€100mg879,00€1mL*10mM (DMSO)226,00€Sodium Camptothecin
CAS:Sodium Camptothecin: plant-derived, antitumor, inhibits RNA/DNA synthesis, disrupts viral DNA.Fórmula:C20H18N2NaO5Pureza:98.93%Cor e Forma:SolidPeso molecular:389.36(S)-crizotinib
CAS:(S)-crizotinib (ent-crizotinib) （IC50 of 72 nM）, an effective MTH1 (NUDT1) inhibitor, is the (S)-enantiomer of crizotinib.Fórmula:C21H22Cl2FN5OPureza:98.52% - 99.47%Cor e Forma:SolidPeso molecular:450.34Didox
CAS:Didox (NSC-324360), a synthetic RR inhibitor, lowers oxidative injury markers in HIV-related dementia.Fórmula:C7H7NO4Pureza:99.83%Cor e Forma:SolidPeso molecular:169.13Lurbinectedin
CAS:Lurbinectedin (PM01183) is a DNA minor groove covalent binder. Lurbinectedin also shows effective anti-tumor activity.Fórmula:C41H44N4O10SPureza:98.11%Cor e Forma:SolidPeso molecular:784.87NITD-2
CAS:NITD-2 is a DENV RdRp inhibitor with poor cell membrane penetration; no vaccine or antiviral for DENV exists.Fórmula:C23H19N3O4SPureza:98.03% - 99.46%Cor e Forma:SolidPeso molecular:433.48Ref: TM-T8886
1mg74,00€5mg170,00€10mg274,00€25mg472,00€50mg655,00€100mg944,00€200mg1.264,00€1mL*10mM (DMSO)188,00€FIT-039
CAS:FIT-039 is a selective and ATP-competitive, orally active inhibitor of CDK9( IC50 : 5.8 μM;CDK9/cyclin T1).Fórmula:C17H18FN3SPureza:98.61%Cor e Forma:SolidPeso molecular:315.41Simeprevir
CAS:Simeprevir (TMC435) is a potent HCV NS3/4A protease inhibitor, and inhibits HCV replication with EC50 of 8 nM.Fórmula:C38H47N5O7S2Pureza:99.45% - 99.92%Cor e Forma:SolidPeso molecular:749.94
