Síntese de DNA/RNA
Os inibidores da síntese de DNA e RNA são compostos que interferem nos processos de replicação e transcrição nas células, impedindo a produção de material genético essencial. Esses inibidores podem atingir várias enzimas e proteínas envolvidas na síntese de ácidos nucleicos, tornando-os ferramentas valiosas para estudar os mecanismos de replicação, transcrição e tradução. Eles também são usados no desenvolvimento de tratamentos para infecções e câncer. Na CymitQuimica, oferecemos uma ampla gama de inibidores da síntese de DNA/RNA para apoiar sua pesquisa em biologia molecular, virologia e desenvolvimento terapêutico.
Foram encontrados 793 produtos de "Síntese de DNA/RNA"
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Tipiracil
CAS:Tipiracil inhibits thymidine phosphorylase, enhancing trifluridine bioavailability, and is studied in colorectal and gastric cancer treatment.Fórmula:C9H11ClN4O2Pureza:99.815%Cor e Forma:SolidPeso molecular:242.66Fosifloxuridine nafalbenamide
CAS:<p>Fosifloxuridine nafalbenamide (NUC 3373), a pyrimidine nucleotide analogue, is a Thymidylate synthase inhibitor.</p>Fórmula:C29H29FN3O9PPureza:95.87%Cor e Forma:SolidPeso molecular:613.53TH588 hydrochloride
CAS:TH588 hydrochloride is first-in-class inhibitor of nudix hydrolase family that selectively and effectively bind and inhibit the MTH1 with IC50 value of 5 nM.Fórmula:C13H13Cl3N4Cor e Forma:SolidPeso molecular:331.63Brequinar
CAS:Brequinar (NSC-368390) is a potent inhibitor of dihydroorotate dehydrogenase, with potent activities against a broad spectrum of viruses.Fórmula:C23H15F2NO2Pureza:99.1% - 99.57%Cor e Forma:SolidPeso molecular:375.37L-Asparaginase
CAS:L-Asparaginase, an enzyme for acute lymphoblastic leukemia treatment, is administered via injection.Fórmula:NAPureza:97%Cor e Forma:SolidPeso molecular:N/AML264
CAS:ML264 (CID-51003603) is a selective kruppel-like factor 5 (KLF5) inhibitor, which potently Inhibits growth of Colorectal Cancer.Fórmula:C17H21ClN2O4SPureza:99.33% - 99.45%Cor e Forma:SolidPeso molecular:384.88Bractoppin
CAS:Bractoppin is a drug-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem (t)BRCT domain (IC50 = 0.074 μM), which selectively inhibitsFórmula:C25H23FN4OPureza:98.38%Cor e Forma:SolidPeso molecular:414.47Ref: TM-T8873
1mg49,00€5mg104,00€10mg166,00€25mg325,00€50mg490,00€100mg737,00€500mg1.483,00€1mL*10mM (DMSO)115,00€Methylproamine
CAS:Methylproamine is a DNA-binding radioprotector , acts by repair of transient radiation-induced oxidative species on DNA.Fórmula:C28H31N7Pureza:99.94%Cor e Forma:SolidPeso molecular:465.59CBFβ Inhibitor
CAS:CBFβ Inhibitor (5-Ethyl-4-(4-methoxy-phenyl)-thiazol-2-ylamine) is a cell-permeable CBFβ inhibitor and inhibits its association with Runx1.Fórmula:C12H14N2OSPureza:96.50%Cor e Forma:SolidPeso molecular:234.32N-Nitrosodiethylamine
CAS:<p>N-Nitrosodiethylamine (NDEA) is a potent hepatocarcinogenic dialkylnitrosoamine.</p>Fórmula:C4H10N2OPureza:99.26% - 99.88%Cor e Forma:SolidPeso molecular:102.14SR18662
SR18662, improved ML264 derivative, inhibits KLF5 at 4.4 nM IC50; curbs colorectal cancer cell growth and triggers apoptosis.Fórmula:C16H19Cl2N3O4SPureza:98.97% - 99.2%Cor e Forma:SolidPeso molecular:420.31Ref: TM-T22429
1mg48,00€5mg96,00€10mg160,00€25mg311,00€50mg502,00€100mg718,00€200mg938,00€500mg1.454,00€1mL*10mM (DMSO)105,00€DMTr-LNA-5MeU-3-CED-phosphoramidite
CAS:<p>DMTr-LNA-5MeU-3-CED-phosphoramidite is a derivative of nucleoside.</p>Fórmula:C41H49N4O9PPureza:98.28%Cor e Forma:SolidPeso molecular:772.82FDI-6
CAS:FDI-6 is an effective and selective inhibitor of FOXM1 that blocks DNA binding. FDI-6 binds to the FOXM1 protein and downregulates FOXM1-activated genes.Fórmula:C19H11F4N3OS2Pureza:98.92% - >99.99%Cor e Forma:SolidPeso molecular:437.43Ref: TM-T4005
1mg37,00€5mg79,00€10mg120,00€25mg202,00€50mg289,00€100mg430,00€200mg630,00€1mL*10mM (DMSO)88,00€dGTP
CAS:dGTP (2'-Deoxyguanosine-5'-triphosphate) is one of the guanosine nucleotides which is highly susceptible to oxidative damage to 8-O-GDP, 8-O-dGTP, 8-O-GTP, andFórmula:C10H16N5O13P3Pureza:99.64%Cor e Forma:SolidPeso molecular:507.18Simeprevir sodium
CAS:Simeprevir is a drug for the treatment and cure of hepatitis C.Fórmula:C38H46N5NaO7S2Pureza:98%Cor e Forma:SolidPeso molecular:771.92CX-5461
CAS:CX5461 is an orally rRNA synthesis inhibitor that inhibits Pol I-driven rRNA transcription. CX5461 has antitumor activity. Cost-effective and quality-assured.Fórmula:C27H27N7O2SPureza:95.44% - 99.4%Cor e Forma:SolidPeso molecular:513.61Remdesivir
CAS:Remdesivir (GS-5734) is a nucleoside analog, a broad-spectrum antiviral compound that exerts its activity by inhibiting the RNA-dependent RNA polymerase ofFórmula:C27H35N6O8PPureza:97.62% - 99.98%Cor e Forma:SolidPeso molecular:602.58Ref: TM-T7766
1mg114,00€5mg305,00€10mg485,00€25mg720,00€50mg892,00€100mg1.359,00€200mg1.786,00€1mL*10mM (DMSO)406,00€Clevudine
CAS:<p>Clevudine (Levovir) fights HBV, blocks viral DNA synthesis, and has a long half-life reducing relapse risk after treatment.</p>Fórmula:C10H13FN2O5Pureza:99.88% - 99.97%Cor e Forma:SolidPeso molecular:260.225-Methylcytosine
CAS:5-Methylcytosine is a methylated nucleotide base found in eukaryotic DNA.Fórmula:C5H7N3OPureza:99.17%Cor e Forma:SolidPeso molecular:125.13BVDV-IN-1
CAS:<p>BVDV-IN-1 is a non-nucleoside inhibitor (NNI) of bovine viral diarrhea virus (BVDV), with an EC50 of 1.8 μM.</p>Fórmula:C20H22N4OPureza:98.43%Cor e Forma:SolidPeso molecular:334.41
