Síntese de DNA/RNA
Os inibidores da síntese de DNA e RNA são compostos que interferem nos processos de replicação e transcrição nas células, impedindo a produção de material genético essencial. Esses inibidores podem atingir várias enzimas e proteínas envolvidas na síntese de ácidos nucleicos, tornando-os ferramentas valiosas para estudar os mecanismos de replicação, transcrição e tradução. Eles também são usados no desenvolvimento de tratamentos para infecções e câncer. Na CymitQuimica, oferecemos uma ampla gama de inibidores da síntese de DNA/RNA para apoiar sua pesquisa em biologia molecular, virologia e desenvolvimento terapêutico.
Foram encontrados 675 produtos para "Síntese de DNA/RNA".
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CBL 0100 free base
CAS:CBL0100 is an inhibitor of viral transcriptional elongation, blocking both HIV-1 replication and reactivation.Fórmula:C24H26N2O2Pureza:98.18% - 98.86%Cor e Forma:White SolidPeso molecular:374.48CB 3731
CAS:CB 3731 is used in fluorine-19 nuclear magnetic resonance studies of binary and ternary complexes of thymidylate synthase.Fórmula:C23H24FN5O6Cor e Forma:SolidPeso molecular:485.46GSK_WRN3
CAS:GSK_WRN3 acts as a selective inhibitor of the WRN protease with an IC 50 of 8.6 μM. It demonstrates significant selectivity by covalently binding to the Cys727 residue of the WRN protein. By inhibiting WRN protease activity, GSK_WRN3 hinders the growth of MSI tumor cells by increasing DNA double-strand breaks and inhibiting cell proliferation [1].Fórmula:C16H20N2O5SCor e Forma:SolidPeso molecular:352.40AP-1/NF-κB activation inhibitor 1
CAS:AP-1/NF-κB activation inhibitor 1 is a potent inhibitor of AP-1 and NF-κB mediated transcriptional activation ( IC 50 =1 μM), does not blocking basalFórmula:C13H11F3N4O4Pureza:99.52% - 99.91%Cor e Forma:SolidPeso molecular:344.25Ref: TM-T9656
1mg70,00€2mg90,00€5mg152,00€1mL*10mM (DMSO)166,00€10mg205,00€25mg334,00€50mg497,00€100mg692,00€500mg1.404,00€D-Xylofuranose, 1,2,3,5-tetraacetate
CAS:1,2,3,5-Tetra-O-acetyl-D-xylofuranose is a starting material for the synthesis of nucleosides.Fórmula:C13H18O9Cor e Forma:SolidPeso molecular:318.28Datelliptium chloride
CAS:Datelliptium chloride is a DNA-intercalating agent derived from ellipticine. Datelliptium chloride shows anti-tumor activities.Fórmula:C23H28ClN3OPureza:98%Cor e Forma:SolidPeso molecular:397.942-Fluoroadenine
CAS:2-Fluoroadenine (NSC-27364) has toxicity in nonproliferating and proliferating tumor cells. 2-Fluoroadenine can be used for anticancer studies.Fórmula:C5H4FN5Pureza:98.84% - 99.62%Cor e Forma:White SolidPeso molecular:153.12DDD100097
CAS:DDD100097 is a N-myristoyltransferase inhibitor with potential inhibitory effects on Trypanosoma brucei, which can be used to study neurological disorders.Fórmula:C22H30Cl2F2N4O2SPureza:99.93%Cor e Forma:SolidPeso molecular:523.47Nitracrine
CAS:Nitracrine: a 1-nitroacridine, hypoxia-selective, anti-tumor agent; inhibits RNA synthesis, binds DNA reversibly and forms covalent adducts.Fórmula:C18H20N4O2Pureza:98%Cor e Forma:SolidPeso molecular:324.38Bofumustine
CAS:Bofumustine is a chloroethyl nitrosourea with anti tumor properties.Fórmula:C18H21ClN4O9Cor e Forma:SolidPeso molecular:472.83BMVC
CAS:BMVC is a potent G-quadruplex (G4) stabilizer and a selective telomerase inhibitor (IC50: ~0.2 μM) with anticancer activities.Fórmula:C28H25I2N3Cor e Forma:SolidPeso molecular:657.33Apricitabine
CAS:Apricitabine (SPD754) is a highly selective and orally active HIV-1 reverse transcriptase inhibitor (Ki=0.08 μM), the (-) enantiomer of 2′-deoxy-3′-oxy-4′-Fórmula:C8H11N3O3SPureza:99.45%Cor e Forma:White SolidPeso molecular:229.26Antitumor agent-84
Antitumor agent-84 stabilizes G-quadruplex DNA, exhibits potent anti-tumor effects.Fórmula:C24H31N7Cor e Forma:SolidPeso molecular:417.55CID 5951923
CAS:CID 5951923 is an inhibitor of KLF5 transcription factor with an IC50 of 603 nM.Fórmula:C16H18N2O7SPureza:99.95%Cor e Forma:SolidPeso molecular:382.39RHI002-Me
CAS:RHI002-Me is a methylated derivative of RHI002, a selective inhibitor of human RNaseH2.Fórmula:C18H19N3O2S2Pureza:98%Cor e Forma:SolidPeso molecular:373.49Glucocorticoid receptor modulator 1
CAS:Glucocorticoid receptor modulator 1 is a orally NF-κB and AP-1 inhibitor, inflammatory factors IL-6, IL-1β, TNF-α, and MMP-13, alleviating skin inflammation.Fórmula:C24H23ClN2O4SPureza:99.79%Cor e Forma:SolidPeso molecular:470.97Ref: TM-T72102
1mg60,00€5mg130,00€1mL*10mM (DMSO)133,00€10mg200,00€25mg401,00€50mg583,00€100mg802,00€Laromustine
CAS:Laromustine (VNP40101M) is a sulfonyl hydrolysis alkylation prodrug for cancer treatment with significant anticancer activity, inhibiting thioredoxin reductase.Fórmula:C6H14ClN3O5S2Pureza:≥98%Cor e Forma:White SolidPeso molecular:307.7810-Formyl-5,8-dideazafolic acid
CAS:10-Formyl-5,8-dideazafolic acid is a thymidylate synthase inhibitor.Fórmula:C22H21N5O7Pureza:96.04%Cor e Forma:White SolidPeso molecular:467.43CM03
CAS:CM03 is a cell-selective G-quadruplex ligand with anti-cancer activity, stabilizing G4 genes, useful in pancreatic cancer research.Fórmula:C34H44N6O6Pureza:98.65%Cor e Forma:SolidPeso molecular:632.75Werner syndrome RecQ helicase-IN-4
CAS:Werner syndrome RecQ helicase-IN-4 is a WRN inhibitor with anticancer and anti-proliferative activity, used in colorectal and gastric cancer research.Fórmula:C32H33F3N8O5Pureza:98.27%Cor e Forma:SolidPeso molecular:666.65
