Síntese de DNA/RNA
Os inibidores da síntese de DNA e RNA são compostos que interferem nos processos de replicação e transcrição nas células, impedindo a produção de material genético essencial. Esses inibidores podem atingir várias enzimas e proteínas envolvidas na síntese de ácidos nucleicos, tornando-os ferramentas valiosas para estudar os mecanismos de replicação, transcrição e tradução. Eles também são usados no desenvolvimento de tratamentos para infecções e câncer. Na CymitQuimica, oferecemos uma ampla gama de inibidores da síntese de DNA/RNA para apoiar sua pesquisa em biologia molecular, virologia e desenvolvimento terapêutico.
Foram encontrados 676 produtos para "Síntese de DNA/RNA".
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Werner syndrome RecQ helicase-IN-4
CAS:Werner syndrome RecQ helicase-IN-4 is a WRN inhibitor with anticancer and anti-proliferative activity, used in colorectal and gastric cancer research.Fórmula:C32H33F3N8O5Pureza:98.27%Cor e Forma:SolidPeso molecular:666.65HBV-IN-4
CAS:HBV-IN-4, a phthalazinone, inhibits HBV DNA replication orally (IC50: 14 nM), encouraging genome-free capsids with strong anti-HBV effects.Fórmula:C24H19ClFN5O3Cor e Forma:SolidPeso molecular:479.89MLAF50
CAS:MLAF50 is an inhibitor of the REV1 UBM2-Ubiquitin interaction.Fórmula:C15H12I2O4Cor e Forma:SolidPeso molecular:510.06Beaucage reagent
CAS:Beaucage reagent, which is found to be effective in causing DNA cleavage.Fórmula:C7H4O3S2Pureza:98.50%Cor e Forma:SolidPeso molecular:200.23ERCC1-XPF-IN-1
CAS:ERCC1-XPF-IN-1: potent ERCC1-XPF inhibitor (IC50: 0.49 μM), hampers CPD removal, boosts UV toxicity, hinders DNA repair.Fórmula:C28H32ClN5O2Cor e Forma:SolidPeso molecular:506.04IACS-4759
CAS:IACS-4759 is a novel potent and selective MTH1 inhibitor with excellent cell permeability and good metabolic stability in microsomes.Fórmula:C10H17N3O2Cor e Forma:SolidPeso molecular:211.26DENV-IN-4
CAS:DENV-IN-4: Effective DENV inhibitor (EC50=4.79 μM), low toxicity (CC50>100 μM), and strong selectivity (SI>20.9); suppresses DENV2 and RdRp.Fórmula:C28H32N4O4SiCor e Forma:SolidPeso molecular:516.66Crisnatol
CAS:Crisnatol (BWA770U) is an oral anticancer DNA intercalator, toxic to breast cancer cells, not skin fibroblasts.Fórmula:C23H23NO2Cor e Forma:SolidPeso molecular:345.43DHX9-IN-1
CAS:DHX9-IN-1 is a DHX9 inhibitor with antitumor activity for related cancer research.Fórmula:C21H21F2N5O3SCor e Forma:SolidPeso molecular:461.49Ref: TM-T82569
1mg205,00€5mg528,00€1mL*10mM (DMSO)537,00€10mg782,00€25mg1.161,00€50mg1.558,00€100mg2.322,00€CB 3717
CAS:CB 3717 is an enzyme inhibitor, antineoplastic agent, folic acid antagonist.Fórmula:C24H23N5O6Cor e Forma:SolidPeso molecular:477.47Thiarabine
CAS:Thiarabine displays effective anti-tumor activity. It also inhibition of DNA synthesis.Fórmula:C9H13N3O4SPureza:98%Cor e Forma:SolidPeso molecular:259.28Zelpolib
CAS:Zelpolib is a specific inhibitor of DNA polymerase δ (Pol δ), inhibiting DNA replication. antiproliferative.Fórmula:C22H21N3O5S2Pureza:98.79%Cor e Forma:Yellow SolidPeso molecular:471.55Antitumor agent-85
Antitumor agent-85 stabilizes G4-DNA with potent anti-tumor effects.Fórmula:C24H33N7Cor e Forma:SolidPeso molecular:419.57Werner syndrome RecQ helicase-IN-3
CAS:Potent WRN inhibitor, Werner syndrome RecQ helicase-IN-3, is orally active with 0.06 µM IC50; exhibits antiproliferative and anticancer effects.Fórmula:C31H30ClF3N8O5Pureza:99.60%Cor e Forma:White SolidPeso molecular:687.07Ref: TM-T72109
1mg205,00€5mg462,00€1mL*10mM (DMSO)698,00€10mg737,00€25mg1.504,00€50mg1.963,00€100mg2.520,00€Crisnatol mesylate
CAS:Crisnatol, a potent and selective DNA intercalator, has potential anticancer activity.Fórmula:C24H27NO5SCor e Forma:SolidPeso molecular:441.54AS-136A
CAS:AS-136A is an orally active MV RdRp inhibitor with antiviral activity that inhibits measles virus and blocks viral RNA synthesis.Fórmula:C17H19F3N4O3SPureza:98.52%Cor e Forma:SolidPeso molecular:416.42Ref: TM-T62160
1mg215,00€5mg537,00€1mL*10mM (DMSO)590,00€10mg802,00€25mg1.369,00€50mg1.783,00€100mg2.395,00€HBV-IN-16
CAS:HBV-IN-16, a quinoline derivative, inhibits HBV cccDNA, key for viral replication (from patent WO2019121357A1).Fórmula:C22H20ClNO4Cor e Forma:SolidPeso molecular:397.85UIAA-II-232
CAS:UIAA-II-232 (compound 19b) is a potent inhibitor of DNA gyrase catalytic (IC 50= 3.5 μM).Fórmula:C20H24FN5O3Cor e Forma:SolidPeso molecular:401.43HIPP
CAS:HIPP is a highly selective inhibitor of antineoplastic CtBP.Fórmula:C9H9NO3Cor e Forma:SolidPeso molecular:179.17ML372
CAS:ML372 is a potent and selective SMN Modulator (EC50 = 12 nM, 325% increase inSMN2) with good potency, pharmacokinetics, tolerance, and CNS penetration.Fórmula:C18H20N2O4SCor e Forma:SolidPeso molecular:360.43
