AMPK
Os inibidores de AMPK são compostos que inibem a Quinase Ativada por AMP (AMPK), uma enzima que desempenha um papel crucial na homeostase energética celular. A AMPK é ativada em resposta a baixos níveis de energia nas células e ajuda a regular processos como a captação de glicose, a oxidação de ácidos graxos e a biogênese mitocondrial. Inibir a AMPK é importante para estudar seu papel em doenças metabólicas, câncer e envelhecimento. Na CymitQuimica, oferecemos uma gama de inibidores de AMPK para apoiar sua pesquisa em metabolismo, oncologia e doenças relacionadas ao envelhecimento.
Foram encontrados 171 produtos de "AMPK"
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COH-SR4
CAS:COH-SR4 (COH-SR4 (Mitochondria uncoupler SR4)) is a uncoupler of mitochondrial oxidative phosphorylation.Fórmula:C13H8Cl4N2OPureza:98.96%Cor e Forma:SolidPeso molecular:350.03Marein
CAS:Marein prevents PC12 cell damage by protecting mitochondria and activating AMPK, potentially countering diabetic encephalopathy.Fórmula:C21H22O11Pureza:99.12% - 99.84%Cor e Forma:SolidPeso molecular:450.39Daphnetin
CAS:<p>Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),</p>Fórmula:C9H6O4Pureza:97.47% - 99.8%Cor e Forma:SolidPeso molecular:178.14Dorsomorphin
CAS:Dorsomorphin (BML-275) is an AMPK inhibitor (Ki=109 nM) that is selective and ATP-competitive.Fórmula:C24H25N5OPureza:98% - 99.06%Cor e Forma:SolidPeso molecular:399.49Bempedoic acid
CAS:Bempedoic acid (ETC1002) is an orally available, once-daily LDL-C lowering small molecule designed to lower elevated levels of LDL-C.Fórmula:C19H36O5Pureza:99.85% - 99.94%Cor e Forma:SolidPeso molecular:344.49Ref: TM-T3625
2mg35,00€5mg52,00€10mg73,00€25mg125,00€50mg217,00€100mg350,00€500mg840,00€1mL*10mM (DMSO)55,00€Mogroside I E1
CAS:Mogroside I E1 is a triterpenoid glycoside isolated from the extracts of Luo Han Guo, is a nonsugar sweetener.Fórmula:C36H62O9Pureza:98.62% - 99.71%Cor e Forma:SolidPeso molecular:638.87Teneligliptin hydrobromide
CAS:Teneligliptin hydrobromide: potent, novel DPP-4 inhibitor; inhibits human/rat plasma DPP-4 with ~1 nM IC50.Fórmula:C22H30N6OSBrHPureza:97.83% - 99.92%Cor e Forma:SolidPeso molecular:628.86Flurbiprofen Axetil
CAS:Flurbiprofen Axetil (Lipfen) is an anti-inflammatory used as an analgesic.Fórmula:C19H19FO4Pureza:97.58% - 98%Cor e Forma:SolidPeso molecular:330.35STF-118804
CAS:STF-118804 is a highly specific NAMPT inhibitor; reduces the viability of most B-ALL cell lines with IC50 <10 nM.Fórmula:C25H23N3O4SPureza:98.66%Cor e Forma:SolidPeso molecular:461.53SBI-0206965
CAS:<p>SBI-0206965 is a potent, selective and cell-permeable autophagy kinase ULK1 inhibitor with IC50 of 108 nM for ULK1 kinase activity and 711 nM for ULK2.</p>Fórmula:C21H21BrN4O5Pureza:99.13%Cor e Forma:SolidPeso molecular:489.32Gomisin J
CAS:Gomisin J is a natural product and have vasodilatory activity.Fórmula:C22H28O6Pureza:99.59% - 99.60%Cor e Forma:SolidPeso molecular:388.45Ref: TM-T3904
1mg47,00€2mg65,00€5mg119,00€10mg188,00€25mg329,00€50mg490,00€100mg700,00€1mL*10mM (DMSO)97,00€GSK-690693
CAS:GSK-690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. Phase 1.Fórmula:C21H27N7O3Pureza:98.07% - 99.77%Cor e Forma:SolidPeso molecular:425.48RSVA405
CAS:RSVA405 is an AMPK activator (EC50 = 1 μM), and is STAT3 inhibitorFórmula:C17H20N4O2Pureza:99.30%Cor e Forma:SolidPeso molecular:312.37MOTS-c(Human) Acetate(1627580-64-6 free)
MOTS-c(Human) Acetate is a mitochondrial-derived peptide.Fórmula:C103H156N28O24S2Pureza:100%Cor e Forma:SolidPeso molecular:2234.64WZ4003
CAS:<p>WZ4003, a highly selective NUAK kinase inhibitor, is with IC50 of 20 nM and 100 nM for NUAK1 and NUAK2, respectively.</p>Fórmula:C25H29ClN6O3Pureza:99.65% - >99.99%Cor e Forma:SolidPeso molecular:496.99PKC-iota inhibitor 1
CAS:PKC-iota inhibitor 1 is an inhibitor of protein kinase C-iota (PKC-ι ; IC50 : 0.34 μM)Fórmula:C21H22N6OPureza:98.82%Cor e Forma:SolidPeso molecular:374.44Ref: TM-T8764
1mg113,00€2mg160,00€5mg230,00€10mg369,00€25mg615,00€50mg879,00€100mg1.198,00€500mg2.395,00€1mL*10mM (DMSO)240,00€MRT67307 HCl (1190378-57-4(free base))
MRT67307 is a kinase inhibitor of TBK1, MARK1-4, IKKε, and NUAK1 (IC50: 19, 27-52, 160, and 230 nM, respectively).Fórmula:C26H37ClN6O2Pureza:98.19%Cor e Forma:SolidPeso molecular:501.07ON123300
CAS:ON123300 is a potent and multi-targeted kinase inhibitor for CDK4/Ark5/PDGFRβ/FGFR1/RET/Fyn (IC50: 3.9/5/26/26/9.2/11 nM).Fórmula:C24H27N7OPureza:99.53% - 99.7%Cor e Forma:SolidPeso molecular:429.52Metformin glycinate
CAS:Metformin glycinate activates AMPK, enhances insulin sensitivity, and reduces glucose absorption for better glycemic control.Fórmula:C6H16N6O2Cor e Forma:SolidPeso molecular:204.23[6]-Gingerol
CAS:[6]-Gingerol ((S)-(+)-[6]Gingerol), an antioxidant, protects HL-60 cells from oxidative stress. It has protective effects for tumors.Fórmula:C17H26O4Pureza:98% - 99.66%Cor e Forma:Light Yellow OilinessPeso molecular:294.39
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