AMPK
Os inibidores de AMPK são compostos que inibem a Quinase Ativada por AMP (AMPK), uma enzima que desempenha um papel crucial na homeostase energética celular. A AMPK é ativada em resposta a baixos níveis de energia nas células e ajuda a regular processos como a captação de glicose, a oxidação de ácidos graxos e a biogênese mitocondrial. Inibir a AMPK é importante para estudar seu papel em doenças metabólicas, câncer e envelhecimento. Na CymitQuimica, oferecemos uma gama de inibidores de AMPK para apoiar sua pesquisa em metabolismo, oncologia e doenças relacionadas ao envelhecimento.
Foram encontrados 161 produtos para "AMPK".
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Resolvin D3
CAS:Resolvin D3 (RvD3) is a dysregulated mediator originating from docosahexaenoic acid (DHA). It plays a crucial role in reducing arthritic inflammation.Fórmula:C22H32O5Cor e Forma:SolidPeso molecular:376.493AMARA peptide
CAS:AMARA peptide: a minimal substrate for SIK, AMPK, and other protein kinases; contains AMPK phosphorylation site.Fórmula:C62H115N27O17SPureza:98%Cor e Forma:SolidPeso molecular:1542.81SAMS
CAS:SAMS peptide is a specific substrate for the AMP-activated protein kinase (AMPK).Fórmula:C74H131N29O18S2Pureza:98%Cor e Forma:SolidPeso molecular:1779.15NUAK1-IN-2
NUAK1-IN-2 (Compound 24) is an inhibitor of NUAK1 with an IC50 of 3.162 nM, as well as an inhibitor of CDK2/4/6. It is applicable in research related to cancer, neurodevelopmental disorders, and Alzheimer's disease.Fórmula:C24H30N6OCor e Forma:SolidPeso molecular:418.535ALKBH1-IN-3
ALKBH1-IN-3 is an effective inhibitor of the DNA N6-methyladenosine (6mA) demethylase ALKBH1. This compound enhances the abundance of 6mA in gastric cancer cell lines HGC27 and AGS, simultaneously inhibiting cell viability and upregulating the AMP-activated protein kinase (AMPK) signaling pathway. ALKBH1-IN-3 holds potential for use in cancer research, including studies on gastric cancer.Cor e Forma:Odour SolidKanglexin
CAS:Kanglexin is an orally active novel anthraquinone compound. It inhibits NLRP3 inflammasome activation and pyroptosis, offering cardioprotective benefits. By stimulating the FGFR1/ERK signaling pathway, Kanglexin promotes angiogenesis and accelerates wound healing in diabetes. Additionally, it has lipid-lowering effects and inhibits vascular smooth muscle cell dedifferentiation, making it a potential compound for studying hyperlipidemia, fatty liver, and atherosclerosis.Fórmula:C21H18O8Cor e Forma:SolidPeso molecular:398.36Glycometabolism Compound Library
xnum glycometabolism-related comounds, can be used for HTS and HCT;Cor e Forma:Odour SolidRef: TM-L2520
1mgA consultar10μL*10mM (DMSO)A consultar20μL*10mM (DMSO)A consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarXY221
XY221 (Compound 16o) selectively inhibits BRD4 BD2 with an IC50 of 5.8 nM. It demonstrates high selectivity for pan-BD2 and BRD4 BD2 domains, being 667 times more selective than for BRD4 BD1, and 9-32 times more selective than for BRD2/3/T BD2. XY221 can induce apoptosis in MV4-11 cells and exhibits anti-cancer activity.Fórmula:C32H34FN3O5Cor e Forma:SolidPeso molecular:559.628N,N-Didesethyl Sunitinib
CAS:N,N-Didesethyl Sunitinib Hydrochloride is a potent AMPK inhibitor with IC50 of 393 nM and 141 nM for AMPKα1 and AMPK2,respectively.Fórmula:C18H19FN4O2Pureza:97.73%Cor e Forma:Orange SolidPeso molecular:342.37Ref: TM-T60128
1mg130,00€5mg313,00€1mL*10mM (DMSO)319,00€10mg439,00€25mg713,00€50mg973,00€100mg1.333,00€Anti-Phospho-AMPKα (Thr172) Antibody (3O988)
Anti-Phospho-AMPKα (Thr172) Antibody (3O988) is a Rabbit antibody targeting Phospho-AMPKα (Thr172). Anti-Phospho-AMPKα (Thr172) Antibody (3O988) can be used in WB.Cor e Forma:Transparent LiquidMetformin-D6 hydrochloride
CAS:Metformin-d6 hydrochloride (Metformin-d6 hydrochloride) is a deuteride of Metformin, which can be used to study Metformin metabolism in vivo.Fórmula:C4H12ClN5Pureza:98.1%Cor e Forma:SolidPeso molecular:171.66Teneligliptin hydrobromide hydrate
CAS:Teneligliptin hydrobromide hydrate: potent, long-lasting DPP-4 inhibitor with ~1 nM IC50.Fórmula:C22H33BrN6O2SCor e Forma:SolidPeso molecular:525.516-Azuridine
CAS:6-Azauridine is a purine analog with antitumor effects, inhibiting DNA synthesis and inducing apoptosis in lymphatic cancers.Fórmula:C8H11N3O6Pureza:99.02%Cor e Forma:SolidPeso molecular:245.19BC1618
CAS:BC1618 (2-Propanol, 1-[bis(phenylmethyl)amino]-3-[4-(trifluoromethyl)phenoxy]-) is an orally active Fbxo48 inhibitor that stimulates Ampk-dependent signaling.Fórmula:C24H24F3NO2Pureza:99.95%Cor e Forma:SolidPeso molecular:415.45O-304
CAS:O-304 is a pan-activator of AMP-activated protein kinase (AMPK).Fórmula:C16H11Cl2N3O2SPureza:99.84% - ≥98%Cor e Forma:White SolidPeso molecular:380.25Ref: TM-T7362
1mg63,00€2mg92,00€5mg137,00€1mL*10mM (DMSO)150,00€10mg205,00€25mg409,00€50mg605,00€100mg860,00€500mg1.728,00€Kahweol
CAS:Kahweol has anticarcinogenic, anti-angiogenic,and anti-inflammatory activities, it can block the LPS-induced activation of NF-kappaB by preventing IkappaBFórmula:C20H26O3Pureza:99.26% - 99.86%Cor e Forma:Off-White To Yellow SolidPeso molecular:314.42AMPK activator 2
CAS:AMPK activator 2, a chloroformin derivative, may boost cancer treatment by enhancing AMPK and inhibiting mTOR pathways, and cancer cell growth.Fórmula:C13H18F3N5Pureza:99.86%Cor e Forma:SolidPeso molecular:301.31Metformin
CAS:Metformin (1,1-Dimethylbiguanide) is an AMPK activator with blood-brain barrier permeability.Fórmula:C4H11N5Pureza:99.77% - >99.99%Cor e Forma:SolidPeso molecular:129.16Ref: TM-T8526
10mg44,00€1mL*10mM (DMSO)44,00€25mg66,00€50mg93,00€100mg102,00€500mg250,00€2500mg414,00€Flurbiprofen Axetil
CAS:Flurbiprofen Axetil (Lipfen) is an anti-inflammatory used as an analgesic.Fórmula:C19H19FO4Pureza:97.58% - 98%Cor e Forma:SolidPeso molecular:330.35EB-3D
CAS:EB-3D is a potent and selective choline kinase alpha 1 (ChoKα1) inhibitor(IC50 : 1 μM).with anti-cancer activity.Fórmula:C30H36Br2N4O2Pureza:99.48%Cor e Forma:SolidPeso molecular:644.4Ref: TM-T7955
1mg87,00€2mg114,00€5mg177,00€10mg260,00€1mL*10mM (DMSO)263,00€25mg447,00€50mg620,00€100mg875,00€200mg1.161,00€
