AMPK
Os inibidores de AMPK são compostos que inibem a Quinase Ativada por AMP (AMPK), uma enzima que desempenha um papel crucial na homeostase energética celular. A AMPK é ativada em resposta a baixos níveis de energia nas células e ajuda a regular processos como a captação de glicose, a oxidação de ácidos graxos e a biogênese mitocondrial. Inibir a AMPK é importante para estudar seu papel em doenças metabólicas, câncer e envelhecimento. Na CymitQuimica, oferecemos uma gama de inibidores de AMPK para apoiar sua pesquisa em metabolismo, oncologia e doenças relacionadas ao envelhecimento.
Foram encontrados 161 produtos para "AMPK".
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STF-118804
CAS:STF-118804 is a highly specific NAMPT inhibitor; reduces the viability of most B-ALL cell lines with IC50 <10 nM.Fórmula:C25H23N3O4SPureza:99.96%Cor e Forma:SolidPeso molecular:461.53COH-SR4
CAS:COH-SR4 (COH-SR4 (Mitochondria uncoupler SR4)) is a uncoupler of mitochondrial oxidative phosphorylation.Fórmula:C13H8Cl4N2OPureza:98.96%Cor e Forma:SolidPeso molecular:350.03ON123300
CAS:ON123300 is a potent and multi-targeted kinase inhibitor for CDK4/Ark5/PDGFRβ/FGFR1/RET/Fyn (IC50: 3.9/5/26/26/9.2/11 nM).Fórmula:C24H27N7OPureza:99.53% - 99.7%Cor e Forma:SolidPeso molecular:429.52EB-3D
CAS:EB-3D is a potent and selective choline kinase alpha 1 (ChoKα1) inhibitor(IC50 : 1 μM).with anti-cancer activity.Fórmula:C30H36Br2N4O2Pureza:99.48%Cor e Forma:SolidPeso molecular:644.4Ref: TM-T7955
1mg87,00€2mg114,00€5mg177,00€10mg260,00€1mL*10mM (DMSO)263,00€25mg447,00€50mg620,00€100mg875,00€200mg1.161,00€Platycodin D
CAS:Platycodin D may stimulate TNF-α synthesis or inhibit degradation of TNF-α mRNA.Fórmula:C57H92O28Pureza:99.2% - 99.65%Cor e Forma:White SolidPeso molecular:1225.32Daphnetin
CAS:Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM),Fórmula:C9H6O4Pureza:97.47% - 99.95%Cor e Forma:SolidPeso molecular:178.14GSK621
CAS:GSK621 is a specific and potent AMPK activator.Fórmula:C26H20ClN3O5Pureza:97.02% - 97.05%Cor e Forma:SolidPeso molecular:489.91Dorsomorphin
CAS:Dorsomorphin (BML-275) is an AMPK inhibitor (Ki=109 nM) that is selective and ATP-competitive.Fórmula:C24H25N5OPureza:98% - 99.06%Cor e Forma:SolidPeso molecular:399.49IMT1
CAS:IMT1 (Propanamide, N,N-dimethyl-2-[[4-(2-methylphenyl)-2-oxo-2H-1-benzopyran-7-yl]oxy]-) has anticancer activity.Fórmula:C21H21NO4Pureza:98.07% - 98.14%Cor e Forma:SolidPeso molecular:351.4Ref: TM-T8841
1mg77,00€5mg166,00€1mL*10mM (DMSO)178,00€10mg285,00€25mg533,00€50mg763,00€100mg1.054,00€AMAROGENTIN
CAS:Amarogentin, extracted from Swertia/Gentiana roots, aids liver cancer prevention/treatment by affecting cell cycle and apoptosis.Fórmula:C29H30O13Pureza:99.98% - ≥95%Cor e Forma:SolidPeso molecular:586.54Ref: TM-T5497
2mg37,00€5mg54,00€1mL*10mM (DMSO)71,00€10mg84,00€25mg152,00€50mg205,00€100mg289,00€200mg439,00€WH-4-025
CAS:WH-4-025 is a Salt-inducible kinase (SIK) inhibitor.Fórmula:C39H38F3N7O5Pureza:99.41%Cor e Forma:White SolidPeso molecular:741.76Ref: TM-T9219
1mg38,00€2mg50,00€5mg84,00€1mL*10mM (DMSO)93,00€10mg130,00€25mg250,00€50mg396,00€100mg585,00€Demethyleneberberine
CAS:Demethyleneberberine, which is composed of a potential antioxidant structure, could penetrate the membrane of mitochondria and accumulate in mitochondria eitherFórmula:C19H18NO4Pureza:98.08% - 99.18%Cor e Forma:SolidPeso molecular:324.35PKC-iota inhibitor 1
CAS:PKC-iota inhibitor 1 is an inhibitor of protein kinase C-iota (PKC-ι ; IC50 : 0.34 μM)Fórmula:C21H22N6OPureza:98.82%Cor e Forma:SolidPeso molecular:374.44Ref: TM-T8764
1mg107,00€2mg152,00€5mg219,00€1mL*10mM (DMSO)226,00€10mg349,00€25mg583,00€50mg833,00€100mg1.134,00€500mg2.268,00€MK-3903
CAS:MK-3903 is a potent and selective AMPK activator (EC50: 8 nM).Fórmula:C27H19ClN2O3Pureza:98.63% - 99.75%Cor e Forma:SolidPeso molecular:454.9Ref: TM-T5187
1mg34,00€5mg75,00€1mL*10mM (DMSO)84,00€10mg114,00€25mg178,00€50mg334,00€100mg557,00€200mg790,00€STO-609
CAS:STO-609 inhibits CaM-KKα/KKβ (Ki: 80/15 ng/mL), is specific, cell-permeable, and targets Ca2+/calmodulin-dependent protein kinase kinase.Fórmula:C19H10N2O3Pureza:97.14% - 99.35%Cor e Forma:SolidPeso molecular:314.29Ref: TM-T3546
1mg39,00€5mg84,00€1mL*10mM (DMSO)93,00€10mg120,00€25mg250,00€50mg400,00€100mg620,00€200mg873,00€IMM-H007
CAS:IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expressionFórmula:C22H23N5O8Pureza:97.73%Cor e Forma:SolidPeso molecular:485.45Ref: TM-T9010
1mg38,00€5mg92,00€1mL*10mM (DMSO)124,00€10mg128,00€25mg215,00€50mg304,00€100mg411,00€200mg570,00€Ginkgolide C
CAS:Ginkgolide C (BN-52022), a natural product, can enhance the cardiac function of rats in the body.Fórmula:C20H24O11Pureza:99.71% - 99.98%Cor e Forma:White PowderPeso molecular:440.40ARN-3236
CAS:ARN-3236 is an oral active and selective inhibitor of salt-inducible kinase 2 (SIK2), (SIK2, SIK1 and SIK3 with IC50s of <1 nM, 21.63 nM and 6.63 nMFórmula:C19H16N2O2SPureza:98.89% - 99.7%Cor e Forma:SolidPeso molecular:336.41Ref: TM-T5993
1mg57,00€5mg92,00€1mL*10mM (DMSO)142,00€10mg152,00€25mg250,00€50mg334,00€100mg512,00€200mg737,00€Nepodin
CAS:Nepodin exhibits antimalarial, anti-inflammatory, and antidiabetic effects by inhibiting COX and activating AMPK to stimulate GLUT4.Fórmula:C13H12O3Pureza:97.9% - 99.12%Cor e Forma:SolidPeso molecular:216.23Ref: TM-TN1100
1mg54,00€2mg80,00€1mL*10mM (DMSO)114,00€5mg120,00€10mg192,00€25mg324,00€50mg480,00€100mg683,00€GSK-690693
CAS:GSK-690693 is a pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 2 nM/13 nM/9 nM, also sensitive to the AGC kinase family: PKA, PrkX and PKC isozymes. Phase 1.Fórmula:C21H27N7O3Pureza:98.07% - 99.77%Cor e Forma:SolidPeso molecular:425.48
