AMPK
Os inibidores de AMPK são compostos que inibem a Quinase Ativada por AMP (AMPK), uma enzima que desempenha um papel crucial na homeostase energética celular. A AMPK é ativada em resposta a baixos níveis de energia nas células e ajuda a regular processos como a captação de glicose, a oxidação de ácidos graxos e a biogênese mitocondrial. Inibir a AMPK é importante para estudar seu papel em doenças metabólicas, câncer e envelhecimento. Na CymitQuimica, oferecemos uma gama de inibidores de AMPK para apoiar sua pesquisa em metabolismo, oncologia e doenças relacionadas ao envelhecimento.
Foram encontrados 168 produtos de "AMPK"
Ordenar por
Pureza (%)
0
100
|
0
|
50
|
90
|
95
|
100
YKL-06-061
CAS:YKL-06-061 is a selective salt-inducible kinase (SIK) inhibitor with IC50 values of 6.56 nM/1.77 nM/20.5 nM for SIK1/2/3, respectively.Fórmula:C30H37N7O2Pureza:99.52% - 99.79%Cor e Forma:SolidPeso molecular:527.66Tizoxanide
CAS:Tizoxanide (Desacetyl-nitazoxanide) is a metabolite of lamivudine.Fórmula:C10H7N3O4SPureza:98.89% - 99.28%Cor e Forma:SolidPeso molecular:265.25Kudinoside D
CAS:Kudinoside D exerts anti-adipogenic effects through modulation of adipogenic transcription factors via AMPK signaling pathway.Fórmula:C47H72O17Pureza:99.66% - 99.92%Cor e Forma:SolidPeso molecular:909.06Annaosanchun
CAS:<p>Annaosanchun (YC-6) is potentially for the treatment of acute ischemic stroke (AIS).</p>Fórmula:C19H32O3Pureza:99.58%Cor e Forma:SolidPeso molecular:308.46ASP4132
CAS:ASP4132 is an orally active AMPK activator (EC50 : 18 nM), has anti-cancer activity.Fórmula:C46H51F3N6O8S2Pureza:98.34%Cor e Forma:SolidPeso molecular:937.06HTH-01-015
CAS:<p>HTH-01-015 is a selective NUAK1 inhibitor (IC50=100 nM).</p>Fórmula:C26H28N8OPureza:98.38% - 99.70%Cor e Forma:SolidPeso molecular:468.55Buformin hydrochloride
CAS:Buformin hydrochloride, an oral biguanide antidiabetic, activates AMPK, enhances insulin sensitivity, and inhibits hepatic glucose production.Fórmula:C6H16ClN5Pureza:97.83%Cor e Forma:SolidPeso molecular:193.68PF-06409577
CAS:PF-06409577 is an effective, orally active, and specific allosteric activator of AMPK (EC50: 7 nM, for α1β1γ1).Fórmula:C19H16ClNO3Pureza:95.17% - 98.21%Cor e Forma:SolidPeso molecular:341.797-Methoxyisoflavone
CAS:7-Methoxyisoflavone is an activator of adenosine monophosphate-activated protein kinase (AMPK).Fórmula:C16H12O3Pureza:99.93% - 99.94%Cor e Forma:SolidPeso molecular:252.26Methyl cinnamate
CAS:<p>Methyl cinnamate, a tyrosinase inhibitor and a flavoring compound, has antimicrobial, antiadipogenic, vasorelaxant, and anti-inflammatory effects.</p>Fórmula:C10H10O2Pureza:99.88%Cor e Forma:Colorless To Pale Yellow Solid CrystallinePeso molecular:162.19Cimiracemoside C
CAS:Cimiracemoside C (Cimicifugoside M) is an active component of Cimicifuga racemosa. It activates AMPK and has the potential activity against diabetes.Fórmula:C35H56O9Pureza:99.95%Cor e Forma:SolidPeso molecular:620.81Karanjin
CAS:Karanjin, a flavonoid from karanja seeds, boosts GLUT4, AMPK in muscles, and triggers cancer cell apoptosis.Fórmula:C18H12O4Pureza:99.01%Cor e Forma:SolidPeso molecular:292.298-Chloroadenosine
CAS:8-Chloroadenosine (NSC-354258) is a 5' AMP-activated protein kinase agonist potentially for the treatment of chronic lymphocytic leukemia.Fórmula:C10H12ClN5O4Pureza:98.75% - 99.84%Cor e Forma:SolidPeso molecular:301.69EX229
CAS:EX229 (C991) is an allosteric activator of AMPK, with Kds of 0.06 μM, 0.06 μM and 0.51 μM for α1β1γ1, α2β1γ1, and α1β2γ1, respectively.Fórmula:C24H18ClN3O3Pureza:99.20% - 99.36%Cor e Forma:SolidPeso molecular:431.87A-769662
CAS:A-769662 is an effective, reversible AMPK activator(EC50=0.8 μM).Fórmula:C20H12N2O3SPureza:97.52% - 99.58%Cor e Forma:SolidPeso molecular:360.39RGX-202
CAS:RGX-202 (β-GPA) is an orally active inhibitor of the SLC6A8 transport protein. RGX-202 is a creatine analog that alters skeletal muscle energy expenditure.Fórmula:C4H9N3O2Pureza:99.67% - 99.8%Cor e Forma:SolidPeso molecular:131.13Chromium(III) acetate
CAS:Chromium(III) acetate （Chromium acetate） is a small molecule ionic crosslinker that is used as a feedstock for the synthesis of other compounds.Fórmula:C2H3O2CrPureza:99.9%Cor e Forma:Blue-Green Powder Environment Immediate Steps Should Be Taken To Limit Its Spread To The Environment It Is Used InPeso molecular:76.37Doxorubicin
CAS:Doxorubicin (Adriamycin) is a Topoisomerase II (Top2) inhibitor with antineoplastic activity.Fórmula:C27H29NO11Pureza:99.31%Cor e Forma:Red Crystalline Solid SolidPeso molecular:543.52AD1058
CAS:<p>AD1058 is a selective ATR inhibitor that crosses the blood-brain barrier with in vivo anticancer activity, used in the study of brain and CNS metastasis.</p>Fórmula:C19H20N6O3SPureza:98.24%Cor e Forma:SolidPeso molecular:412.47Asteltoxin
CAS:Asteltoxin is a useful organic compound for research related to life sciences. The catalog number is T124203 and the CAS number is 79663-49-3.Fórmula:C23H30O7Cor e Forma:SolidPeso molecular:418.486
