mTOR
Os inibidores de mTOR são compostos que inibem a atividade do Alvo da Rapamicina em Mamíferos (mTOR), um regulador central do crescimento celular, proliferação, metabolismo e sobrevivência. A via de sinalização mTOR é frequentemente alterada em casos de câncer e outras doenças, tornando o mTOR um alvo crítico para intervenções terapêuticas. Inibidores de mTOR são amplamente utilizados em pesquisas relacionadas ao câncer, envelhecimento e distúrbios metabólicos. Na CymitQuimica, oferecemos uma variedade de inibidores de mTOR para apoiar sua pesquisa em transdução de sinais, oncologia e desenvolvimento terapêutico.
Foram encontrados 163 produtos de "mTOR"
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Thioridazine hydrochloride
CAS:Thioridazine hydrochloride (Mellaril) , an antipsychotic drug, is used in the therapy of psychosis and schizophrenia and shows serotonin antagonism or D4Fórmula:C21H27ClN2S2Pureza:99.55% - 99.957%Cor e Forma:White To Off-White SolidPeso molecular:407.04MT 63-78
CAS:MT 63-78 is a specific and effective direct AMPK activator (EC50: 25 μM).
Fórmula:C21H14N2O2Pureza:97.11%Cor e Forma:SolidPeso molecular:326.35Rapamycin
CAS:Rapamycin, a macrolide from Streptomyces hygroscopicus, inhibits mTOR (IC50: 0.1 nM) and promotes autophagy with immunosuppressive effects.Fórmula:C51H79NO13Pureza:97.08% - 99.80%Cor e Forma:Yellow SolidPeso molecular:914.17Ref: TM-T1537
1g268,00€10mg34,00€25mg46,00€50mg50,00€100mg65,00€200mg101,00€500mg178,00€1mL*10mM (DMSO)48,00€NSC781406
CAS:NSC781406 is a highly effective inhibitor of PI3K and mTOR (IC50: 2 nM for PI3Kα).Fórmula:C29H27F2N5O5S2Pureza:99.58%Cor e Forma:SolidPeso molecular:627.68Ref: TM-T16355
2mg39,00€5mg60,00€10mg87,00€25mg159,00€50mg231,00€100mg355,00€200mg505,00€1mL*10mM (DMSO)84,00€SN32976
CAS:SN32976 is a pan PI3K inhibitor. SN32976 potently inhibited PI3K isoforms and mTOR, displaying preferential activity for PI3Kα and sparing of PI3Kδ.Fórmula:C24H33F2N9O4SPureza:98.06%Cor e Forma:SolidPeso molecular:581.64NV-5138
CAS:NV-5138 is a selective and orally active activator of brain mTORC1, with antidepressant effects.Cost-effective and quality-assured.Fórmula:C7H13F2NO2Pureza:98% - ≥98%Cor e Forma:SolidPeso molecular:181.18Ref: TM-T12270
1mg89,00€5mg215,00€10mg344,00€25mg737,00€50mg1.169,00€100mg1.691,00€1mL*10mM (DMSO)170,00€(32-Carbonyl)-RMC-5552
CAS:(32-Carbonyl)-RMC-5552, a potent mTOR inhibitor, blocks mTORC1/C2, with pIC50 values >9 for p-P70S6K and p-4E-BP1, and 8~9 for p-AKT1/2/3.Fórmula:C93H134N10O24Cor e Forma:SolidPeso molecular:1776.141RMC-4529
CAS:RMC-4529 is a chemical compound that demonstrates potent inhibition, with an IC50 value of 1.0 nM, against p-4E-BP1-(T37/46) in mTOR kinase cellular assays.Fórmula:C90H139N13O23Cor e Forma:SolidPeso molecular:1771.172DII
2DII is a potent and selective mTORC2 inhibitor. It specifically binds to the mSin1 PH domain, resulting in a decreased phosphorylation of AKT1.Fórmula:C54H76ClN7O11SCor e Forma:SolidPeso molecular:1066.74PI3K-IN-22
CAS:PI3K-IN-22 is a dual kinase inhibitor of PI3Kα and mTOR, with IC50s of 0.9 and 0.6 nM respectively. PI3K-IN-22 could be used in cancer.Fórmula:C31H35F3N8O3Cor e Forma:SolidPeso molecular:624.66RMC-4627
CAS:RMC-4627 is a selective mTORC1 inhibitor that activates 4EBP1 and inhibits tumor growth.Fórmula:C93H141N11O23Cor e Forma:SolidPeso molecular:1781.17mTOR inhibitor WYE-28
CAS:mTOR inhibitor WYE-28, Potent mTOR (IC50=0.08 nM) and PI3Kα (IC50=6 nM) inhibitor, short half-life in mouse microsomes.Fórmula:C30H34N8O5Cor e Forma:SolidPeso molecular:586.65PF-06465603
CAS:PF-06465603 is a metabolite of PF-04691502, a highly potent and selective ATP competitive kinase inhibitor of class 1 PI3Ks and mTOR.Fórmula:C22H25N5O5Cor e Forma:SolidPeso molecular:439.46RMC-6272
CAS:RMC-6272 (RM-006) is a bi-steric mTORC1 inhibitor with selective potency over mTORC2 and shows greater effects than Rapamycin on TSC2-deficient tumors.Fórmula:C95H141FN6O27SCor e Forma:SolidPeso molecular:1850.25FDA-Approved Kinase Inhibitor Library
A unique collection of 263 kinase inhibitors/regulators for specific targeting of kinases, ready for high-throughput screening and high-content screening.
Cor e Forma:LiquidQL-IX-55
CAS:QL-IX-55 has a wide range of applications in life science related research.Fórmula:C24H14F4N4OCor e Forma:SolidPeso molecular:450.39Aschantin
CAS:Aschantin is a useful organic compound for research related to life sciences. The catalog number is T126072 and the CAS number is 13060-15-6.Fórmula:C22H24O7Cor e Forma:SolidPeso molecular:400.427Kinase Inhibitor Library
A unique collection of 2720 kinase inhibitors/regulators for high throughput screening and high content screening for drug discovery in kinase related diseases;Cor e Forma:Odour SolidRef: TM-L1600
1mgA consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultarPI3K-AKT-mTOR Compound Library
A unique collection of 420 compounds targeting PI3K/Akt/mTOR signaling for research in PI3K/Akt/mTOR signaling, and drug discovery in diseases involved withCor e Forma:Odour SolidRef: TM-L1300
1mgA consultar30μL*10mM (DMSO)A consultar50μL*10mM (DMSO)A consultar100μL*10mM (DMSO)A consultar250μL*10mM (DMSO)A consultar
