Compostos Policiclícos

<p>Applications 5-Hydrazino-2(1H)-quinolinone Hydrochloride is an intermediate used in the synthesis of sodium-hydrogen exchanger type 1 inhibitor (NHE-1).<br></p>

<p>Applications 2-(2-Chloroethyl-d4)-1H-isoindole-1,3-dione (cas# 1252995-10-0) is a compound useful in organic synthesis.<br></p>

<p>Stability Store in freezer at -20°C<br>Applications 5-Amino-6-(methylamino)quinoline (cas# 14204-98-9) is a compound useful in organic synthesis.<br></p>

<p>Boc-(3S)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid is an amino acid that has the δ-opioid receptor antagonist activity. It can be synthesized by a stepwise synthesis with an asymmetric center. The δ-opioid receptor antagonist activity of Boc-(3S)-1,2,3,4-Tetrahydroisoquinoline-3-carboxylic acid was found to be comparable to naloxone in terms of affinity constants and functional groups.</p>

<p>Boc-L-indoline-2-carboxylic acid is a high quality, versatile building block that can be used as a reagent or intermediate in organic synthesis. It is used as a research chemical and has potential applications in the development of new drugs. Boc-L-indoline-2-carboxylic acid is a complex compound that reacts with nucleophiles to form valuable products. It also has the ability to bind to metal ions such as copper, zinc, and nickel. This product can be used in reactions involving amines, alcohols, amides, phenols, carboxylic acids, sulfonic acids, and other compounds.</p>

2-Azabicyclo[2.2.1]heptane is a lactam that has been synthesized in the laboratory. The compound exhibits significant antiproliferative activity and is shown to have a stereoselective, stereogenic, nucleophilic attack on amides. 2-Azabicyclo[2.2.1]heptane has been used to study the mechanisms of neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease. The conformational properties of this compound can be determined by NMR spectra, which show that it has a skeleton with significant conformational flexibility.

3-(2-Chlorophenyl)-2-phenyl-3H-indole is a versatile building block that can be used as a precursor in the synthesis of a wide range of complex compounds. 3-(2-Chlorophenyl)-2-phenyl-3H-indole has been shown to be an effective reagent for the synthesis of heterocycles and useful for the preparation of diverse speciality chemicals. 3-(2-Chlorophenyl)-2-phenyl-3H-indole is also an important intermediate in the synthesis of pharmaceuticals, agrochemicals, dyes, and perfumes. It is also a useful scaffold for organic chemistry reactions and can serve as a reaction component because it contains two reactive groups.

(S,S,S)-2-Azabicyclo[3.3.0]octane-3-carboxylic acid benzyl ester hydrochloride is a research chemical that can be used as a reaction component or reagent in organic synthesis. This compound is also useful in the construction of complex compounds and fine chemicals with applications including drug discovery, pharmaceuticals, agrochemicals, and polymer chemistry.

<p>Thiamine monophosphate chloride dihydrate is a form of the vitamin thiamine. It has been used in control analysis to measure the activity of enzymes that require thiamine as a cofactor, such as transketolase and pyruvate kinase. Thiamine monophosphate chloride dihydrate has also been studied in biochemical properties, where it was found that this compound can be cleaved by picolinic acid to form thiazole phosphate. The matrix effect is an important factor in polymerase chain reactions and has been shown to be dependent on the presence of dinucleotide phosphate. This compound is an essential component of energy metabolism and plays a role in protein synthesis. Thiamine monophosphate chloride dihydrate also has toxicological studies, including a model system using wild-type strains of yeast. These studies have shown that this compound leads to physiological effects such as inhibition of glycolysis and lactic acid production.</p>

<p>2-Amino-5(6)-benzoylbenzimidazole is an antifilarial and anthelmintic drug that belongs to the benzimidazole class. It is used for the treatment of filarial infections in humans, including lymphatic filariasis, which is caused by worms transmitted by mosquitoes. 2-Amino-5(6)-benzoylbenzimidazole has low bioavailability due to its poor water solubility. The drug can be administered orally or topically and is metabolized in the liver. The metabolites are excreted in urine as glucuronides and sulfates.</p>

<p>3-Aminoquinoline is a chemical compound that inhibits the activity of the epidermal growth factor receptor (EGFR). It is a potent inhibitor of cell proliferation and has been shown to have antitumour activity. 3-Aminoquinoline has been shown to inhibit the proliferation of carcinoma cell lines. This drug binds to the EGFR receptor, preventing it from activating downstream signalling pathways that control cell growth. 3-Aminoquinoline also has biological properties, including matrix-assisted laser desorption/ionization time-of-flight mass spectrometry, analytical chemistry, sample preparation, and Suzuki coupling reaction. The molecule is structurally analyzed using chemical structures and structural analysis techniques such as thermodynamic data or proton NMR spectroscopy. 3-Aminoquinoline also interacts with sugars through hydrogen bonding and oligosaccharides. These interactions are found to be high in value in some cases.</p>

6'-Dehydromarmin is a natural product, classified as a coumarin derivative, which is primarily sourced from certain plant species, notably within the Rutaceae family. This compound arises through the biochemical transformation of secondary metabolites in plants, typically involving oxidation processes that occur under specific enzymatic conditions.

<p>Tert-Butyl 2,5-diazabicyclo[2.2.1]heptane-2-carboxylate hydrochloride (TBDAHC) is a fine chemical that is an intermediate for the synthesis of other compounds. TBDAHC is a versatile building block that can be used in research chemicals, reaction components, and specialty chemicals. It is also a useful scaffold for making complex compounds and useful building blocks. The compound has high quality and can be used as a reagent in organic chemistry.</p>

<p>6-Fluoroindole-3-acetic acid is a molecule that has been synthesized by the reaction of 6-fluoroindole with acetic anhydride. When mixed with acetonitrile, the fluorescence of 6-fluoroindole-3-acetic acid can be seen in the solution. The fluorescence intensity is proportional to the concentration of this molecule. 6-Fluoroindole-3-acetic acid is used as a template molecule for fluorescence labeling experiments. It interacts with hormones and can be used to identify their conformations and interactions. This compound has been shown to have anticancer properties in mice, and it may also be effective against cancer cells in humans. It has also been shown to inhibit the growth of pisum sativum (pea).</p>

<p>5-Chloroindole-2-carboxylic acid is a fatty acid that is synthesized from glucose. It has been shown to have inhibitory properties against the enzyme cyclooxygenase-2 (COX-2), which may be due to its ability to suppress prostaglandin synthesis. 5-Chloroindole-2-carboxylic acid also has been shown to have anticancer properties and can inhibit cancer cell growth in vitro. The drug may also play a role in the central nervous system, as it has been shown to cause neuronal death. 5-Chloroindole-2-carboxylic acid is not water soluble, so it must be dissolved in organic solvents such as cyclohexane or chloroform before being used for chemical reactions. This drug can be used with other drugs that are coxib sensitive, such as aspirin, acetaminophen, and ibuprofen.</p>

<p>3-(2-Diisopropylaminoethyl)indole hydrochloride is an inhibitor of the enzyme monoamine oxidase (MAO). MAO is responsible for the degradation of monoamines such as serotonin, dopamine, and norepinephrine. 3-(2-Diisopropylaminoethyl)indole hydrochloride inhibits these enzymes in order to increase the levels of these neurotransmitters in the brain. These effects are observed with a sectional study on the host plant species. 3-(2-Diisopropylaminoethyl)indole hydrochloride has been shown to have low potency for inhibiting 5-HT1A and 5-HT2A receptors in rat studies, but it is not active against 5-HT2C receptors. This drug was used to measure urinary serotonin and dopamine levels in human urine samples.</p>

<p>(1R,3S,5S)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane is a versatile building block that can be used in the synthesis of complex compounds. It is a reagent and speciality chemical with applications in research or as a useful intermediate in the synthesis of other chemicals. (1R,3S,5S)-3-(3-Isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane is also a useful scaffold for the synthesis of other compounds with specific properties such as high quality and usefulness as reaction components.</p>

<p>Quinoline-2,8-diol is a bacterial strain that can be used to remove fatty acids from wastewater. The recombinant cytochrome P450 in this strain can degrade fatty acids, which are carcinogenic and have been shown to cause hepatic steatosis. In addition, the quinoline-2,8-diol strain has shown an ability to inhibit xenograft tumor growth in mice by activating cytochrome P450 and inducing apoptosis. This bacterial strain also has the potential to produce xanthurenic acid from tyrosine. Xanthurenic acid is toxic and has been shown to inhibit polymerase chain reaction (PCR) amplification of DNA. Quinoline-2,8-diol may be used as a model for experimental studies of xanthurenic acid's effects on energy metabolism and DNA synthesis.</p>

<p>2-Bromoquinoline is an antimicrobial agent that binds to bacterial receptors. It is a bifunctional molecule with two reactive groups: a hydroxyl group and a nitrogen atom. 2-Bromoquinoline has been shown to inhibit the growth of various bacteria, including Mycobacterium tuberculosis, Staphylococcus epidermidis and Streptococcus pyogenes, by preventing the formation of a proton gradient across the bacterial membrane. 2-Bromoquinoline also inhibits hyperproliferative diseases such as amyloidosis in mice by binding to amyloid fibrils. This drug has been shown to cause DNA damage in mammalian cells, which may be due to its ability to form hydrogen bonds with methyl ethyl groups on DNA bases.</p>

<p>2,2,4-Trimethyl-1,2-dihydroquinolin-6-ol (TQ) is a naturally occurring phenolic compound that has been shown to inhibit lipid peroxidation in animal and human cells. TQ is an antioxidant that protects against oxidative damage by scavenging free radicals. This compound can act as a nitroxyl radical trap and inhibits the dimerization of quinones and other reactive oxygen species. TQ also has been found to have anti-inflammatory effects, which may be due to its ability to reduce the production of inflammatory cytokines.<br>A new study shows that TQ can inhibit the production of reactive oxygen species in quantum yields up to 10%. It is thought that this effect may be due to TQ’s ability to stabilize different forms of reduced glutathione.</p>