Investigação do cancro
A pesquisa sobre o câncer envolve o estudo das causas, progressão e tratamento do câncer. Isso inclui a compreensão dos fatores genéticos e ambientais que contribuem para o desenvolvimento do câncer, suas ferramentas de diagnóstico e a descoberta de novas terapias. Na CymitQuimica, oferecemos uma ampla gama de compostos e reagentes para apoiar a pesquisa sobre o câncer, auxiliando no desenvolvimento de tratamentos eficazes e melhorando os resultados dos pacientes.
Foram encontrados 1873 produtos de "Investigação do cancro"
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Withanolide A
CAS:Produto Controlado<p>Applications Withanolide A, is a neuritogenic steroid. It may act as deterrent for feeding insect larva and other herbivores. Withaferin A, causes activation of Notch2 and Notch4 in human breast cancer cells, and thus used as novel anticancer agents.<br>References Liffert, R., et al.: Chemical Science, 4, 2851 (2013); Lee. J., et al.: Breast Cancer, Res. treat., 136, 45 (2012);<br></p>Fórmula:C28H38O6Cor e Forma:NeatPeso molecular:470.60N-Dechloroethyl Cyclophosphamide
CAS:<p>Stability Reacts with DMSO<br>Applications A metabolite of Cyclophosphamide (C988580).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Bohnenstengel, F., et al.: Eur. J. Clin. Pharmacol., 51, 297 (1996), Busse, D., et al.: J. Clin. Oncol., 15, 188 (1997), Roy, P., et al.: Drug Metab. Dispos., 27, 655 (1999),<br></p>Fórmula:C5H12ClN2O2PCor e Forma:NeatPeso molecular:198.59(2R,3S)-N-Benzoyl-3-phenyl Isoserine Methyl Ester
CAS:Produto Controlado<p>Applications (2R,3S)-N-Benzoyl-3-phenyl Isoserine Methyl Ester is an intermediate in the preparation of potent anticancer drug Paclitaxel (P132500) used to study the location of the binding sites.<br>References Paal, K. et al.: Bioorg. Med. Chem., 15, 1323 (2007); Krawczyk, E. et al.: J. Pharm. Pharmacol., 57, 791 (2005);<br></p>Fórmula:C17H17NO4Cor e Forma:Off White PowderPeso molecular:299.32Anastrozole Monoamide
CAS:<p>Impurity Anastrozole Monoamide Impurity<br>Applications Anastrozole Monoamide is a derivative of Anastrozole (A637425), an aromatase inhibitor. Used as an antineoplastic.<br>References Plourde, P.V., et al.: Breast Cancer Res. Treat., 30, 103 (1994), Buzdar, A.U., et al.: Cancer, 79, 730 (1997)<br></p>Fórmula:C17H21N5OCor e Forma:WhitePeso molecular:311.387-Ethyl-10-(4-N-aminopentanoic acid)-1-piperidino)carbonyloxycamptothecin
CAS:Produto Controlado<p>Applications A major metabolite of Irinotecan.<br>References Canal, P., et al.: J. Clin. Oncol., 14, 2688 (1996), Haaz, M., et al.: Cancer Res., 58, 468 (1998), Kehrer, D., et al.: Clin. Cancer Res., 6, 3451 (2000), Hanioka, N., et al.: Xenobiotica, 31, 687 (2001), Satoh, T., et al.: Drug Metab. Dispos., 30, 488 (2002),<br></p>Fórmula:C33H38N4O8Cor e Forma:Light YellowPeso molecular:618.6768cis-Etoposide
CAS:<p>Applications cis-Etoposide is an anticancer agent that has half-life of 2 days at pH 7.4 and 37° resulting in the loss of 90% of the active drug within 1 week during in vitro incubations.<br>References Mader, R. M., et al.: Cancer Chemotherapy and Pharmacol., 27, 354 (1991)<br></p>Fórmula:C29H32O13Cor e Forma:NeatPeso molecular:588.56N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine
CAS:Produto Controlado<p>Applications N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine is an active metabolite of Maytansine (M197940), inhibits in vitro polymerization of tubulin and is used in the treatment of advanced breast cancer.<br>References Remillard, S., et. al.: Science, 189, 1002 (1975); Prota, A.E., et. al.: P. Natl. Acad. Sci. USA, 111, 13817 (2014)<br></p>Fórmula:C36H50ClN3O10SPureza:>90%Cor e Forma:NeatPeso molecular:752.31Methotrexate (1 mg/mL in Methanol with 0.1N NaOH)
CAS:Fórmula:C20H22N8O5Cor e Forma:Single SolutionPeso molecular:454.44Anastrozole Acid Amide
<p>Applications Anastrozole Acid Amide is a derivative of Anastrozole (A637425), an aromatase inhibitor. Used as an antineoplastic.<br>References Plourde, P.V., et al.: Breast Cancer Res. Treat., 30, 103 (1994), Buzdar, A.U., et al.: Cancer, 79, 730 (1997)<br></p>Fórmula:C17H22N4O3Cor e Forma:NeatPeso molecular:330.38Nilotinib Monohydrochloride Monohydrate
CAS:Produto ControladoFórmula:C28H22F3N7O·ClH·H2OCor e Forma:NeatPeso molecular:583.99Melphalan
CAS:Produto Controlado<p>Applications Melphalan is an antineoplastic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Ross, W.C.J., et al.: Biochem. Pharmacol., 13, 969 (1964); Donelli, M.G., et al.: J. Pharm. Pharmacol., 18, 760 (1966), Furner, R.L., et al.: Cancer Treat. Rep., 64, 559 (1980),<br></p>Fórmula:C13H18Cl2N2O2Cor e Forma:NeatPeso molecular:305.20Dodecyl Phthalate-d4
CAS:Produto Controlado<p>Applications Labelled Dodecyl Phthalate (D525380). Dodecyl Phthalate is used in the preparation of Cytarabine (C998100) derivatives as anticancer agents.<br>References Aoshima, M., et al.: Cancer Res., 36, 2726 (1976), Wang, N., et al.: Bioorg. Med. Chem. Lett., 15, 4064 (2005), Marie-Helene, G., et al.: Bioorg. Med. Chem., 2009, 17, 6340 (2009),<br></p>Fórmula:C20H26D4O4Cor e Forma:NeatPeso molecular:338.47Eptaplatin
CAS:Produto Controlado<p>Applications A coordination compound for treatment of cervix cancer.<br>References Jiang, M., et al.: Methods Mol. Biol., 292, 401 (2005), Fujii, T., et al.: Int. J. Oncol., 29, 541 (2006), Niu, X., et al.: Int. J. Gynecol. Cancer, 16, 743 (2006),<br></p>Fórmula:C8H18N2O2·C3H2O4PtCor e Forma:NeatPeso molecular:471.36N-Demethyl-3-methoxy-4-hydroxytamoxifen Hydrochloride (E,Z mixture)
CAS:Produto Controlado<p>Applications N-Demethyl-3-methoxy-4-hydroxytamoxifen is an metabolite of Tamoxifen (T006000), a selective estrogen response modifier (SERM), protein kinase C inhibitor and anti-angiogenetic factor.<br>References Zhang, F., et al.: Chem. Rs. Toxicol., 13, 53 (2000); Sutherland, R., et al.: Nature, 267, 434 (1977); Lerner, L., et al.: Cancer Res., 50, 4177 (1990); Love, R., et al.: J. Clin. Oncol., 20 2559 (2002)<br></p>Fórmula:C26H30ClNO3Cor e Forma:NeatPeso molecular:439.97Olaparib
CAS:Fórmula:C24H23FN4O3Pureza:>95.0%(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:434.47DL-Aminoglutethimide
CAS:Fórmula:C13H16N2O2Pureza:>98.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:232.28Bakuchiol
CAS:Fórmula:C18H24OPureza:>98.0%(HPLC)Cor e Forma:Colorless to Yellow clear liquidPeso molecular:256.39Ellagic Acid
CAS:Fórmula:C14H6O8Pureza:>95.0%(T)(HPLC)Cor e Forma:White to Light yellow powder to crystalPeso molecular:302.19WZ 811
CAS:Fórmula:C18H18N4Pureza:>97.0%(T)Cor e Forma:White to Almost white powder to crystalPeso molecular:290.37[6]-Shogaol
CAS:Fórmula:C17H24O3Pureza:>90.0%(HPLC)Cor e Forma:Light yellow to Yellow clear liquidPeso molecular:276.38
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