Building Blocks

Applications 6-Amino-1-hexanol is used in the synthesis of guanidino analogs of roscovitine, which is a cyclin-dependant kinase. Also used in the preparation of tocotrienols which maintain anticancer, antiproliferative and antimigratory activity. Behery, F
References Doleckova, I. et al.: Eur. J. Med. Chem., 62, 443 (2013); Behery, F. et al.: Eur. J. Med. Chem., 59, 329 (2013);

Applications N-Boc-1,6-diaminohexane (cas# 51857-17-1) is a compound useful in organic synthesis.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 3,5-Dichloroiodobenzene is used as a glycolate oxidase inhibitors.
References Wang, Bing. et al., PCT Int. Appl. 737 pp.(2019)

Applications 2,6-Pyridinedicarboxaldehyde is an intermediate used to prepare functionalized resin Amberlite XAD-4, boron-dipyrromethene (BODIPY)-based fluorescence probe with a N,N′-(pyridine-2, 6-diylbis(methylene))-dianiline substituent and novel N-heterocyclic chitosan aerogel derivatives.
References Karada?, C., et al.: Food Chem., 141, 655 (2013); Lu, H., et al.: J. Phys. Chem. A: Molecules, Spectroscopy, Kinetics, Environment and General Theory, 113, 14081 (2009)

Applications 3-(Hydroxymethyl)Benzamide (cas# 126926-34-9) is a useful research chemical.

Applications A is the deuterated isotope of N-Boc-Ethylenediamine (B655006). N-Boc-Ethylenediamine is used in the synthesis of Thyronamine derivatives and analogs.
References Anon., et al.: J. Pharmacol., 58, 53 (1936), Boissier, J., et al.: Eur. J. Pharmacol., 22, 141 (1973),

Applications 4-Hydroxy-5-Methoxy-2-Pyridinecarbaldehyde is used in the synthesis of N-substituted γ-pyridones
References Korenova, A., et al.: CHEM. PAP., 51, 383-389 (1997)

Applications 6-Heptynoic Acid is used as a reagent in organic synthesis, inlcuding that of some novel triazole derivatives which display antiproliferative activity and also of acetylenic fatty acids and their esters.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Pertino, M., et al.: Molecules, 19, 2523 (2014); Nakatani, M., et al.: B. Chem. Soc. Jpn., 59, 3535 (1986);

Applications Triethylenetetramine is a selective Cu(II) chelator and crosslinker.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Applications 2,6-Piperazinedione Hydrochloride is a synthetic intermediate that can be used to prepare anti-inflammatory or antitumor compounds. 2,6-Piperazinedione Hydrochloride is also applicable for the synthesis of 4-succinamoyl-piperazine-2,6-dione derivatives, which are compounds with analgesic properties.
References Shvedaite, I. P., et al.: Pharmaceut Chem J 33, 313 (1999); Shvedaite, I. P. and Shimkyavichene, V. I.: Pharmaceut Chem J  33, 359 (1999); Svedaite, I.: Chemija 18, 50 (2007)

Applications 2-Piperazinone (cas# 5625-67-2) is a compound useful in organic synthesis.

Applications Boronic acid derivatives and their binding affinities with diols.
References Yang, W., et al.: Bioorg. Med. Chem. Lett., 12, 2175 (2002), Yang, W., et al.: Med. Res. Rev., 23, 346 (2003),

Applications Diethyl Ketomalonate (cas# 609-09-6) is a compound useful in organic synthesis.

Applications 4-Chlorobutyronitrile (cas# 628-20-6) is a compound useful in organic synthesis.

Applications Used in the preparation of optically pure L-(+)-Ergothioneine.
References Lehn, J., et al.: Science, 291, 2331 (2001), Nicoll, A., et al.: Org. Biomol. Chem., 2, 2175 (2004),

Applications 4-​Hydrazinobenzoic acid hydrochloride (cas# 24589-77-3) is a useful research chemical.

Applications 4-Iodo-N,N-dimethylaniline is a useful reactant for organic reactions and the synthesis of various compounds.
References Luo, X., et al.: Org. Lett., 20, 2997-3000 (2018); Hamasaka, G., et al.: Adv. Synth. Catal., 360, 1833-40 (2018);

Stability Not determined
Applications 2-Hydroxyethylhydrazine is a reagent that is used in the preparation of dichlorophenoxymethyl-substituted pyrazolones and analogs as neuroprotectors against cytoxicity from protein aggregation of mutant superoxide dismutase 1.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Trippier, P. C., et al.: Bioorg. Med. Chem. Lett., 22, 6647 (2012); Rothstein, J., et al.: Anal. Nuerol, 65, S3 (2009)

Applications 3-Bromo-benzenebutanoic Acid is a reactant used in the preparation of pyrrolo-(di)-benzazocinones via an intramolecular cyclization of N-acyliminium ions formed from 4,4-diethyoxybutyl amides (Erratum)
References King, F.D., et al.: Org. Biomol. Chem., 7, 5271 (2009); King, F.D., et al.: Org. Biomol. Chem., 7, 167 (2009)

Applications Sodium Octanoate-d15 (CAS# 56408-90-3) is a useful isotopically labeled research compound.

Applications 2-Acetyl-5-methylfuran is a useful research chemical and a synthesis intermediate.
References Rong, J., et al.: Org. Lett., 20, 4081 (2018); Zhou, Y., et al.: Chem. Biol. Drug Des., 90, 936 (2017); Smit, F. J., et al.: Med. Chem. Res., 25, 568 (2016)

Applications 2-Chloro-5-chlorosulfonylbenzoic Acid (cas# 137-64-4) is a compound useful in organic synthesis.

Applications A metabolite Methaqualone (M225900). Controlled substance.
References Ericsson, O., et al.: Acta Pharmaceut. Suecica, 15, 81 (1978), Wilson, K., et al.: Eur. J. Drug Metab. Pharmacokinet., 9, 301 (1984),

Applications Adenine Hydrochloride can be utilized in uses for enhanced detection of hydrogen peroxide with platinized microelectrode arrays for analyses of mitochondria activities. It can also be used for biological use in method for producing Cordyceps sinesis by fermentation.
References Ben-Amor, S., et al.: Electrochim. Acta., 126, 171-178 (2014); Jia, J., et al.: Faming Zhuanli Shenqing, CN 101407767 A 20081117 (2008);

Applications 1-Bromo-2-methoxy-d3-ethane is a useful isotopically labeled compound of 2-Bromoethyl Methyl Ether (B685140)

Applications 1-Ethyl-2-piperazinone is used in the synthesis of piperidine and piperazine derivatives as cognition enhancers.
References Bioorg, Med. Chem., 16, 1431 (2008);

Applications 5-Nitropyridin-2(1H)-one can be used for molecular crystal optical materials.
References Uemya, T., et.al., Jpn. Kokai Tokkyo Koho, 22, (1995);

Applications 4-Chlorobiphenyl-2',3',4',5',6'-d5 (CAS# 51624-37-4) is a useful isotopically labeled research compound.

Applications Bromobenzene-2,4,6-d3 (CAS# 13122-41-3) is a useful isotopically labeled research compound.

Applications 1-(2-Hydroxy-4,6-dimethylphenyl)-ethanone was investigated for its properties as an antibacterial agent and urease inhibitory effects.
References Ngan, L.T., et al.: J. Agri. Chem., 60, 9062 (2012); Chermenskaya, T.D., et al.: Industrial. Crops. Prod., 36, 122 (2012);

Applications Bromobenzene-2,3,5,6-d4 (CAS# 64646-03-3) is a useful isotopically labeled research compound.

Applications 3-Nitrobenzyl-d6 Alcohol (CAS# 1219795-18-2) is a useful isotopically labeled research compound.

Applications 3-Hydroxy-4-nitrobenzoic acid is a compound that is capable of inhibiting chloroplast development in linseed and oat seedlings. 3-Hydroxy-4-nitrobenzoic acid also exhibits inhibitory effects on Ras proteins, making them potentially useful compounds in treating cancer.
References Columno, S., et al.: Curr. Cancer Drug Tar., 10, 192 (2010); Price, D. & Wain, R.: Ann. Appl. Biol., 83, 115 (1976)

Applications Diethyl 4-oxopimelate

Applications 2-Bromo-6-fluorobenzaldehyde is used as a reagent in the synthesis of novel 2-carbonylbenzo[b]thiophene 1,1-dioxides as potent inhibitors of STAT3 signaling pathway. 2-Bromo-6-fluorobenzaldehyde is also used in the preparation of 1-Cyano-6-(methylsulfonyl)-7-nitro-9H-xanthen-9-one (C981885) which is an impurity of the herbicide Mesotrione (M225765).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ji, P., et al.: ACS Med. Chem. Lett., 6, 1010 (2015)

Applications p-Hydroxypropiophenone is a 4-hydroxyphenyl ketone used in the preparation of potential antitumor agents. p-Hydroxypropiophenone is a lignin degrradation product.
References Masselter, S. et al.: Chromatographia, 40, 51 (1995); Andreani, A. et al.: Arch. Pharm., 317, 583 (1984);

Applications Diethyl Oxalopropionate is a useful precursor in the synthesis of 2-Methylcitric Acid (M265080); a metabolite of Citric Acid (C521000) that can also be formed from condensation of propionoyl-CoA and oxaloacetic acid catalyzed by a citrate synthase enzyme.
References Allen, R. H., et al.: Metabolism, 42, 978 (1993)

Applications 6-Bromo-3-cyanoindole

Applications syn-2-Pyridinealdoxime is a 2-substituted pyridine derivative with inhibitory activity against prolyl-4-hydroxylase. syn-2-Pyridinealdoxime is used in the preparation of DNA-binding silver nitrate complexes. syn-2-Pyridinealdoximeis the N-demethylated analogue of AChE inhibitor Pralidoxime (P701120).
References Dowell, R.I. et al.: Eur. J. Med. Chem., 28, 513 (1993); Hoskovcova, M. et al.: Neuroendorinol. Lett., 30, 152 (2009); Abu-Youssef, M.A.M.: Inorg. Chem., 49, 9788 (2010);

Applications 4-Chloroiodobenzene is used as a reagent in the synthesis of Clothiapine (C588550); an atypical antipsychotic of the dibenzothiazepine chemical class that has shown efficacy in treatment-resistant schizophrenic patients.
References Schmutz, J., et al.: Helvetica Chimica Acta 50, 245 (1967); Geller, V., et al.: Schizophrenia Research 80 (2-3), 343 (2005)

Applications 4-(1-Piperazinyl)-1H-indole Dihydrochloride (cas# 84807-09-0) is a compound useful in organic synthesis.

Stability Moisture Sensitive
Applications Chlorocarbonylsulfenyl chloride is a useful research chemical for organic synthesis and other chemical processes.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Sorra, K., et al.: Int. J. Mol. Sci., 15, 16500 (2014); Gurjar, A. S., et al.: Bioorg. Chem., 57, 90 (2014); Enache, L., et al.: e-EROS Encyclopedia of Reagents for Organic Synthesis, 1 (2005)

Applications 2-Iodopropane-2-d1 (CAS# 95927-03-0) is a useful isotopically labeled research compound.

Applications 1-Iodopropane-1,1,3,3,3-d5 (CAS# 1219794-94-1) is a useful isotopically labeled research compound.

Applications N1,N4-Di-p-tolylbenzene-1,4-diamine is a useful intermediate for the preparation of some chemically active substances for polymeric materials.
References Belorossova, A. G., et al.: Uchenye Zapiski Yaroslavskogo Tekhnologicheskogo Instituta, 11, 200 (1969)

Applications 4-Bromo-2-nitroaniline is used for the synthesis of reagents such as ethyltriphenylphosphonium tribromide;
References Jamir, L., et al.: Synthetic. Comm., 41, 147 (2011); Reuter, R., et al.: Euro. J. Org. Chem., 32, 5647 (2009);

Stability Hygroscopic
Applications 2-hydroxycyclopentan-1-one (cas# 473-84-7) is a useful research chemical.

Applications 2,3-Dichlorophenol-OD (CAS# 59457-02-2) is a useful isotopically labeled research compound. It can used for IR spectroscopy.
References Parthasarathy, S., et. al., J. Annamalai University, 30, 89-94, (1972);

Applications 1-Bromo-3,5-difluorobenzene-d3 (CAS# 1219798-73-8) is a useful isotopically labeled research compound.

Applications Ethyl Decanoate-d19 is a useful isotopically labeled compound of Ethyl Decanoate (E911480)

Applications 4-hydroxy-1H,2H-pyrrolo[1,2-d][1,2,4]triazin-1-one (cas# 50269-88-0) is a useful research chemical.

Applications 1-Bromo-2,6-difluorobenzene-d3 (CAS# 1219803-73-2) is a useful isotopically labeled research compound.

Applications 2-Propane-d7-thiol (CAS# 1219803-56-1) is a useful isotopically labeled research compound.

Applications 2-Bromo-6-morpholinobenzonitrile (cas# 1129540-65-3) is a useful research chemical.

Applications 2-Iodopropane-1,1,1,3,3,3-d6 (CAS# 39091-64-0) is a useful isotopically labeled research compound.

Applications Methyl Isocyanoacetate, is used in the Cu-catalyzed, diastereoselective synthesis of oxazolines (O846550).
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ideguchi, T., et al.: J. American Chem. Soc., 135, 12568 (2013);

Applications 2,2-Difluoromalonamide is a useful reagent for the synthesis of fluorine-containing endothiopeptide analogs.
References Pikun, N. V., et al.: ARKIVOC (Gainesville, FL, US), 36-44 (2018)

Applications Photoreduction of N-methylphthalimide (NMP) with 2,3-dimethyl-2-butene h and the selective electroreduction of N-methylphthalimide to 3-hydroxy-2-methyl-isoindolin-1-one have been studied.
References Mazzocchi, P., et al.: J. Am. Chem. Soc., 106, 7567 (1984); Villagran, C., et al.: Ultrasonics Sonochemistry, 12, 423 (2005)

Applications 4-Hydroxy-1-methylpiperidine

Applications 1-Iodopropane-2,2-d2 (CAS# 25493-15-6) is a useful isotopically labeled research compound.

Applications Trimethyl Orthopropionate-2,2,3,3,3-d5 (CAS# 1219803-49-2) is a useful isotopically labeled research compound.

Applications 2-Amino-5,6-dihydro-4h-benzothiazol-7-one

Applications 2-Iodopropane-d7 is the isotope labelled analog of 2-Iodopropane (I718795); a reagent used in the synthesis of 4'-O-alkyl-chitobiosyl-4-methylumbelliferone as human chitinase fluorogenic substrates.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Duivenvoorden, B.A., et al.: Carbohyd. Res., no vol., no pp. (2014, ahead of print)

Applications Tetramethyl-d12-ammonium Bromide (CAS# 284474-82-4) is a useful isotopically labeled research compound.