Reagentes Sintéticos

<p>Applications Castanospermine is a plant alkaloid shown to be a potent inhibitor of lysosomal a-or beta- glucosidase. It also inhibits mammalian glucosidase 1 and beta-mannosidase from sweet almonds and fungal beta-xylosidase.<br>References Arch. Biochem. Biophys., 221, 593 (1983), Clin. Biochem., 17, 3 (1984), Trends Bio. Sci., 9, 32, (1984), J. Biol. Chem., 260, 15873-15879 (1985), FEBS, 1985, 28 (1986)<br></p>

<p>Applications Acalabrutinib, is an experimental anti-cancer drug and a selective Bruton's tyrosine kinase (BTK) inhibitor. This kinase transmits signals from B-cell Receptor (BCR), and thus any genetic BTK mutation causes B-Cell immunodeficiency. Therefore, BTK inhibitors targeting B-cell signaling has shown great promise for the treatment of chronic lymphocytic leukemia (CLL).<br>References Byrd; et al. (2015). "Acalabrutinib (ACP-196) in Relapsed Chronic Lymphocytic Leukemia."; "AstraZeneca to buy Acerta for blood cancer drug". www.rsc.org. Chemistry World - Royal Society of Chemistry. Retrieved 24 December 2015.<br></p>

<p>Applications Sodium Orthovanadate is an inhibitor of several phosphatases and kinases. General inhibitor of tyrosine phosphatases, a large family of enzymes that catalyze the removal of phosphate groups from tyrosine residues.<br>References Khalil, A. A., et al.: Biochem., 82, 149-155 (2017)<br></p>

<p>Applications Hepes<br></p>

<p>Stability Hygroscopic<br>Applications (-)-(18-Crown-6)-2,3,11,12-tetracarboxylic Acid is a chiral NMR solvating agent used for determining the enantiomeric purity and absolute configuration of β-amino acids. It is also used as a solvating agent in the chiral NMR discrimination of pyrrolidines.<br>References Wenzel, T.J., et al.: Tetrahedron-Assymetr., 20, 2052 (2009); Lovely, A.E., et al.: Chirality, 20, 370 (2008); Li, R., et al.: Fenxi Ceshi Xuebao, 26, 305 (2007); Lovely, A.E., et al.: Tetrahedron-Assymetr., 17, 2642 (2006)<br></p>

<p>Applications A PDE7 inhibitor that has acceptable selectivity for in vivo studies. Potent PDE-7 inhibitor.<br>References Smith, S.J., et al.: Mol. Pharmacol., 66, 1679 (2004)<br></p>

<p>Applications (S)-3-Aminopiperidin-2-one is used in preparation of Thiazoleurea derivatives for use as antitumor agents.<br>References Donald, E., et al.: PCT Int. Appl., (2020);<br></p>

<p>Applications Ethyl 3-Furoate is the ethyl ester derivative of 3-Furoic Acid (F863770) and is used as a reagent in the synthesis of disubstituted furan derivatives which exhibit antidiabetic activity. Also used as a reagent in the synthesis of sulfonylfuran ureas as selective endothelial lipase inhibitors.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Babu, S.P., et al.: Pharma Chem., 4, 2178 (2012); Goodman, K.B., et al.: Bioorg. Med. Chem. Lett., 19, 27 (2009)<br></p>

<p>Applications Methyl (S)-N-Tritylaziridine-2-carboxylate (cas# 75154-68-6) is a compound useful in organic synthesis.<br></p>

<p>Applications 9-Fluorenemethanol is used in the design and in the synthesis of novel type somatostatin analogs with antiproliferative activities on A431 tumor cells.<br>References Miyazaki, A., et al.: Tetrahedron Lett., 45, 6323 (2004)<br></p>

<p>Applications 1,5-Diazabicyclo[4.3.0]non-5-ene is used as a nucleophilic catalyst for the Freidel-Crafts C-acylation of pyrroles and indoles. 1,5-Diazabicyclo[4.3.0]non-5-ene is also an inhibitor of indoleamine-N-methyltransferase (II) of rabbit lung in vitro.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mandel, L.: Biochem. Pharmacol., 25, 2251 (1976); Taylor, J., et al.: Org. Lett., 12, 5740 (2010)<br></p>

<p>Applications Iodic Acid is used in the synthesis of silybin derivatives showing antiradical and antioxidant activities. Also used in the iodination of compounds.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Gazak, R. et al.: Bioorg. Med. Chem., 12, 5677 (2004); Zangade, S. et al.: Eur. j. Chem., 3, 314 (2012);<br></p>

<p>Applications A dihydropyridine calcium channel blocker.<br>References Ikeda, K., et al.: Oyo Yakuri, 44, 433 (1992), Hosono, M., et al.: J. Pharmacobio-Dyn., 15, 547, (1992), Ishii, M.: Japan Pharmacol. Ther., 21, 59 (1993),<br></p>

<p>Applications Cobalt Carbonyl is a metal carbonyl used as a reagent and catalyst in organometallic chemistry and organic synthesis. Cobalt Carbonyl is commonly used as a hydroformylation catalyst for the conversion of alkenes to aldehydes.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mirbach, M. et al.: J. Am. Chem. Soc., 103, 7594 (1981); Haukka, M. et al.: J. Mol. Cat. A Chem., 102, 79 (1995); Haumann, M. et al.: Catal. Tod., 79, 43 (2003);<br></p>

<p>Applications Alizapride is a dopamine antagonist with prokinetic and antiemetic effects. Alizapride is used in the treatment of post-operative nausea and vomitting.<br>References Bleiberg, H. et al.: Cancer Chemother. Pharmacol., 22, 316 (1988);<br></p>

<p>Stability Hygroscopic<br>Applications A drug used for the treatment of atrial fibrillation and atrial flutter in patients who have suffered cardiac arrhythmias.<br>References Singh, B., et al.: J. Cardiovas. Pharmacol., 52, 300 (2008), Hoy, S., et al.: Drugs, 69, 1647 (2009), Hohnloser, S., et al.: New Eng. J. Med., 360, 668 (2009),<br></p>

<p>Applications Atosiban is an oxytocin receptor blocking agent in the treatment of experimental endometriosis and was shown exhibit significant therapeutic efficiency.<br>References Simsek, Y., et al.: Arch. Gynecol. Obstet., 286, 777 (2012); Mak, P., et al.: J. Psychopharmacol., 26, 532 (2012); Simsek, Y., et al.: Arch. Gynecol. Obstet., 285, 655 (2012);<br></p>

<p>Applications Tetraethylammonium Bromide, can be used as a source of tetraethylammonium ions for various pharmaceutical studies. It has also the ability to block K+ channels in various tissues.<br>References Kevill, D.N., et al.: J. Am. Chem. Soc., 83, 3812 (1961); Armstrong, C.M. et al.: J. Gen. Physiol. 59, 388 (1972);<br></p>

<p>Applications Arbutin is a glycosylated hydroquinone extracted from bearberry plant. Arbutin is a known inhibitor of tyrosinase, which in turn prevents the formation of melanin. Arbutin is often used as a skin-lightening agent in cosmetic products.<br>References Magnusson, B., et al.: J. Invest. Dermatol., 52, 268 (1969), Goodwin, B., et al.: Contact Dermatitis, 7, 248, (1981), ,Itoh, M., et al.: J. Dermatol., 9, 223 (1982), Sugimoto, K., et al.: Biol. Pharm. Bull., 24, 510 (2004)<br></p>

<p>Applications A non-peptide proteaseinhibitor.<br>References Ayoyama, T., et al.: Chem. Pharm. Bull., 33, 1458 (1985)<br></p>

<p>Applications (1S,2S,3R,5S)-(+)-2,3-Pinanediol is a bicyclic monoterpene diols that has been shown to induce differentiation of S91 melanoma and PC12 pheochromocytoma cells and thus provide possible therapeutic and sunless tanning use. It is also used in the transformation of isopinocampheol and caryophyllene oxide.<br>References Brown, D.A. et al.: Pigment Cell Res., 12, 36 (1999); Noma, Y. et al.: Flav. Frag. J., 25, 161 (2010);<br></p>

<p>Applications Fundamental starting material for organic synthesis.Metabolite of dibromobenzene in urine of rabbit.<br>References Ruzo, L., et al.: J. Agric. Food Chem., 24, 291 (1976),<br></p>

<p>Applications Halogenated derivative of Febrifugine. Used as an antiprotozoal (coccidiostat).<br>References McIntosh, L., et al.: Biochem. Cell Biol., 73, 181 (1995), Leshem, Y., et al.: Exp. Cell Res., 274, 288 (2002),<br></p>

<p>Applications Sodium Phosphate Buffer Solution is used in the development of liquid chromatographic assay for determination of opicapone and BIA 9-1079 in rat matrixes. in the design of novel pyrimidin-4(3H)-one hydroxamate derivatives that showes inhibitory activity against histone deacetylase and exhibited antiproliferative activities against human cervical cancer HeLa and lung carcinoma A549 cells.<br>References Lu, H., et al.: Chem. Res. Chin. Univ., 32, 576 (2016); Goncalves, D., et al.: Biomed. Chromatogr., 30, 312 (2016)<br></p>

<p>Applications Iodine monochloride is a powerful elecrtrophilic iodinating agent used for aromatic substitution. Iodine monochloride is also used to synthesize radioiodinated fatty acids for heart imaging.<br> E0<br>References Robinson Jr., G. &amp; Lee, A.: J. Nuc. Med., 16, 17 (1975); Woollett, G. &amp; Johnson, W.: Org. Synth. Coll., 2, 196, 343 (1943)<br></p>

<p>Applications ABT 199 is a potent and selective BCL-2 inhibitor that achieves potent antitumour activity while sparing platelets. It’s practical application is to treat chronic lymphocytic leukaemic cells and estrogen receptor-positive breast cancer.<br>References Davids, M. &amp; Letai, A.: Cancer Cell, 23, 139 (2013); Souers, A.,et al.: Nat. Med., 19, 202 (2013); Vaillant, F., et al.: Cancer Cell, 24, 120 (2013); Vogler, M., et al.: Brit. J. Haematol., 163, 139 (2013);<br></p>

<p>Applications (1R,3S)-Camphoric Acid is used primarily as a reagent in syntheses of crystalline structures. It is used in the preparation of polymeric transition metal dipyridylamine D-camphorate complexes.<br>References Blake, K. et al.: Crys. Growth Des., 12, 5215 (2012);<br></p>

<p>Applications Adenosine receptors are related to many diseases such as cardiovascular, autoimmune, and cancer. CGS 21680 is a potent and selective agonist of the adenosine A2A receptor, a member of G protein coupled receptor (1,2,3).<br>References (1) Jones, K. R., et al.: Sci Rep. 7, 44816 (2017) (2) Hutchison, A. J., et al.: J. Pharm. Exp. Ther. 251, 47 (1989) (3) Hasko, G., et al.: Nat. Rev. Drug Discov. 7, 759 (2008)<br></p>

<p>Applications Antidepressant.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kent, J., et al.: Lancet, 355, 911 (2000), Pacher, P., et al.: Curr. Med. Chem., 8, 89 (2001), Titier, K., et al.: Ther. Drug Monit., 25, 581 (2003), Eap, C., et al.: Ther. Drug Monit., 26, 152 (2004),<br></p>

<p>Applications Brolitene was studied as one of palmitoylethanolamide derivatives as anticonvulsants and antidepressants.<br>References Guan, L., et al.: Med. Chem. Res., 20, 601 (2011);<br></p>

<p>Applications A neuroprotective effect of lithium carbonate in amyotrophic lateral sclerosis (ALS). Dyes and metabolites.<br>References Gordon, P., et al.: Lancet Neurol., 6, 1045 ( 2007), Shin, J., et al.: Mol. Pharmacol., 71, 965 (2007), Chio, A., et al.: Amyotroph. Lateral Scler., 10, 310 (2009),<br></p>

<p>Applications Pixantrone is an antineoplastic drug belonging to group of antitumor antibiotics. Pixantrone is an anlogue of Mitoxantrone (M373425) and is just as potent in the treatment of multiple sclerosis with fewer toxic effects on cardiac tissue. Studies suggest that Pixantrone significantly reduces amyloid beta (A beta(1-42)) neurotoxicity, a mechanism implicated in Alzheimer's disease.<br>References Cavalletti, E. et al.: Invest. New Drugs, 25, 187 (2007); Gonsette, R.E. et al.: J. Neurol. Sci., 223, 81 (2004); Colombo, R. et al.: Electrophoresis, 30, 1418 (2009)<br></p>

<p>Stability Hygroscopic<br>Applications Clothiapine, is a atypical antipsychotic of the dibenzothiazepine chemical class. It has shown efficacy in treatment-resistant schizophrenic patients.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Schmutz, J., et al.: Helvetica Chimica Acta 50, 245 (1967); Geller, V., et al.: Schizophrenia Research 80 (2-3), 343 (2005);<br></p>

<p>Applications Trametinib (DMSO Solvate) is a highly potent and selective MEK inhibitor with significant antitumor activity.<br>References Abe, H., et al.: ACS Med. Chem. Lett., 2, 320 (2011)<br></p>

<p>Applications Mercury(II)Oxide is used in the synthesis of a mercury based superconductor.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Shimoyama, J. et al.: Phys. Super. Appl., 224, 1 (1994); Maignan, A. et al.: Phys. C. Super., 243, 233 (1995);<br></p>

<p>Applications α-Arbutin is a component used in the skin-whitening cosmetics.<br>References Magnusson, B., et al.: J. Invest. Dermatol., 52, 268 (1969), Goodwin, B., et al.: Contact Dermatitis, 7, 248, (1981), ,Itoh, M., et al.: J. Dermatol., 9, 223 (1982), Sugimoto, K., et al.: Biol. Pharm. Bull., 24, 510 (2004),<br></p>

<p>Applications Irreversible inhibitor of ornithine decarboxylase, an enzyme involved in polyamine biosynthesis. Antineoplastic; antipneumocystic; antiprotozoal (Trypanosoma). Used in the treatment of hirsutism.<br>References Bacchi, C.J., et al.: Science, 210, 332 (1980); Haegele, K.D., et al.: Clin. Pharmacol. Ther., 30, 210 (1981); Meyskens, F.L., et al.: Clin. Cancer Res., 5, 945 (1999);<br></p>

<p>Applications Hydrazine Dihydrochloride (cas# 5341-61-7) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>

<p>Applications AZD-9291 Mesylate is a potent and selective epidermal growth factor receptor (EGFR) inhibitor.<br>References Finlay, M.; et al.: J. Med. Chem., 57, 8249 (2014)<br></p>

<p>Applications A biphosphonate bone resorption inhibitor.<br>References Green, J.R., et al.: J. Bone Min. Res., 9, 745 (1994), Risser, F., et al.: J. Pharm. Biomed. Anal., 15, 1877 (1997), Body, J.J., Cancer, 80, 1699 (1997),<br></p>

<p>Applications A synthetic diethyl-ether of Estradiol with no distal hormonal effects, in patients undergoing surgical correction for stress urinary incontinence (SUI).<br>References Kelleher, C., et al.: Br. J. Obstet. Gynaecol., 104, 1374 (1997), Deffieux, X., et al.: J. Gynecol. Obstet. Biol. Reprod., 35, 678 (2006),<br></p>

<p>Applications Labelled D-Glucose is a simple sugar that is present in plants. A monosaccharide that may exist in open chain or cyclic conformation if in solution. It plays a vital role in photosynthesis and fuels the energy required for cellular respiration. D-Glucose is used in various metabolic processes including enzymic synthesis of cyclohexyl-α and β-D-glucosides. Can also be used as a diagnostic tool in detection of type 2 diabetes mellitus and potentially Huntington's disease through analysis of blood-glucose in type 1 diabetes mellitus.<br>References Wang, R., et al.: J. Mol. Catal. B. Enz., 56, 131 (2009); Springhorn, C. et al.: J. Clin. Endocrinol. Metab., 97, 4640 (2012); Hashimoto, K. et al.: J. Clin. Endocrinol. Metab., 97, 3016 (2012); Avelange, M. et al.: Plant. Phys., 94, 1157 (1990); Cramer, C. et al.: J. Chem. Soc., 115, 5745 (1993);<br></p>

<p>Applications Elacridar Hydrochloride is a dual P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) inhibitor.<br>References Chuan Tang, S., et al.: Int. J. Cancer, 134, 1484 (2014); Durmus, S., et al.: Mol. Pharm., 9, 3236 (2012)<br></p>

<p>Applications Triptolide is a diterpenoid triepoxide with immunosuppressant and antitumor properties.<br>References Hikim, S., et al.: J. Androl., 21, 431 (2000), Chang, W.-T., et al.: J. Biol. Chem., 276, 222 (2001), Kiviharju, T.M., et al.: Clin. Cancer Res., 8, 2666 (2002), Leuenroth, S.J., et al.: Chem. Biol., 12, 1259 (2005),<br></p>

<p>Applications A group of nonpolar cyclic oligopeptides with immunosupppressant activity.<br>References van Wartburg, A., et al.: Prog. Med. Chem., 25, 1 (1988), Jorgensen, K.A., et al.: Scand. J. Imunol., 57, 93 (2003), Vollenbroeker, et al.: Transplant. Proc., 37, 1741 (2005),<br></p>

<p>Applications A biphosphonate bone resorption inhibitor.<br>References Fraser, W.D., et al.: Postgrad. Med. J., 73, 496 (1997),<br></p>

<p>Applications Cognition enhancer related to Piracetam. Nootropic.<br>References Foltyn, P., et al.: Arzneim.-Forsch., 33, 865 (1983), Yamada, K., et al.: Pharmacol. Biochem. Behav., 22, 645 (1985), Schlappi, B., et al.: Drug Invest., 5, 50 (1993),<br></p>

<p>Stability Moisture Sensitive<br>Applications Tributylphenyltin acts as a reagent for the synthetic preparation of tetrahydroisoquinolines and SAR as potential HIV-1 antivirals.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Swidorski, J. J., et al.: Bioorg. Med. Chem. Lett., 26, 160 (2016)<br></p>

<p>Applications (1R,2R)-1,2-Diphenyl-1,2-ethanediamine (cas# 35132-20-8) is a compound useful in organic synthesis.<br></p>

<p>Applications Ho2O3 (cas# 12055-62-8) is a useful research chemical.<br></p>

<p>Applications SGI-1027 is a quinoline derivative and a potent inhibitor of DNA methyltransferase (DNMT). SGI-1027 can be used as a potential therapeutic agent for the treatment of cancer and other diseases and also as a research tool to investigate the role of DNMTs in epigenetic events.<br>References Rilova, E., et al.: Chem. Med. Chem., 9, 590 (2014); Yoo, J., et al.: PLoS One, 8, e62152 (2013); Medina-Franco, J.L., et al.: Mol. Divers., 17, 337 (2013); Yoo, J., et al.: Curr. Comput-aid. Drug, 8, 317 (2012)<br></p>

<p>Applications EGTA is a calcium chelator. EGTA protects mature oligodendrocytes from NO generated by S-nitroso-N-acetyl-penicillamine.<br>References Nielsen, A.D., et. al.: Anal. Biochem., 314, 227 (2003); Boullerne, A., et. al.: J. Neurosci. Res., 63, 124 (2001)<br></p>

<p>Applications Cobalt(II) thiocyanate is best known for the cobalt thiocyanate test (or Scott test), which is a proven screening test for the presence of cocaine.<br>References Swiatko, J., et al.: J. Forensic Sci., 48, 581 (2003); O’ Neal, C., et al.: Forensic Sci. Inter., 109, 189 (2000)<br></p>

<p>Applications Calcium nitrate tetrahydrate is a chemical used in the manufacture of fertilizers.<br></p>

<p>Applications Potassium Hydrogen Sulfate is a reagent used in organic synthesis and ceramics production.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kromer, M. et al.: Langmuir, 33, 13295 (2017); Sevsek, A. et al.: MedChemComm., 8, 2050 (2017);<br></p>

<p>Stability Hygroscopic<br>Applications Vitamin (enzyme cofactor). Essential cofactor of fatty acid metabolism; required for the transport of fatty acids through the inner mitochondrial membrane. Synthesized primarily in the liver and kidney; highest concentrations found in heart and skeletal muscle. Dietary sources include red meat, dairy products, beans, avocado.<br>References Mitchell, M.E., et al.: Am. J. Clin. Nutr., 31, 293 (1978), Lango, R., et al.: Cardiovasc. Res., 51, 21 (2001), Vaz, F.M., et al.: Biochem. J., et al.: 361, 417 (2002), Karlic, H., et al.: Nutrition, 20, 709 (2004),<br></p>

<p>Applications 2-(Aminomethyl)pyrazine is a useful synthetic intermediate. It is used to synthesize pyrazolo[4,3-c]pyridinediones as orally bioavailable NADPH oxidase isoform 4 inhibitors for the treatment of idiopathic pulmonary fibrosis. It is also used to prepare pyrazolyl-indoles with the abilities to induce T-cell kinase inhibition.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Laleu, B., et al.: J. Med. Chem., 53, 7715 (2010); Velankar, A., et al.: Bioorg. Med. Chem., 18, 4547 (2010)<br></p>

<p>Applications Ranitidine (cas# 66357-35-5) was used as a standard for testing the therapeutic effect of brown propolis extract against aspirin and ethanol- induced gastric ulcers.<br>References Patil, M., et al.: Eur. J. Biomed. Pharma. Sci., 7, 620 (2020)<br></p>

<p>Applications VX-765 shows anti-convulsant activity by inhibiting interlukin-1β biosynthesis.<br>References Maroso, M. et al.: Neurother., 8, 304 (2011); Galatsis, P. et al.: Bioorg. Med. Chem. Lett., 20, 5184 (2010);<br></p>

<p>Applications Potassium fluoride is used as a catalyst in the Aldol condensation of nitroalkanes (e.g. 1-Nitrohexane [N496125]) and aliphatic aldehydes (e.g. 2-Propyl Valeraldehyde [P838325]). Potassium fluoride is also used as a reference standard for fluoride ion activity in analytical samples. Potassium fluoride is also found in dental products, and is thought to be toxic in high amounts.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Kambe, S. &amp; Yasuda, H.: Bull. Chem. Soc. Japan, 41, 1444 (1968); Robinson, R., et al.: Anal. Chem., 43, 1862 (1971); Whitford, G.: Dent. Res., 66, 1056 (1987)<br></p>

<p>Applications Inhibits release of allergic mediators from mast cells. Antiallergic; antiasthmatic. Amlexanox, used to treat asthma and mouth sores in humans, may also be a promising treatment for type 2 diabetes and obesity (Nat. Med., DOI: 10.1038/nm.3082).<br>References Rankov, G., et al.: Ophthalmic Res., 22, 359 (1990), Greer, R.O., et al.: J. Oral Mxillofac. Surg., 51, 243 (1993); Chem. and Eng. News p. 43, Feb. 18, 2013<br></p>

<p>Impurity Acetazolamide Disulphide Impurity<br>Applications bis(2-Acetamido-1,3,4-thiadiazol-5-yl) Disulfide is an impurity of Acetazolamide (A161500), a carbonic anhydrase inhibitor. Diuretic. (Acetazolamide Disulphide Impurity)<br>References Srinivasu, P., et. al.: J. Pharmaceut. Biomed. Anal., 52, 142 (2010); Vitale, R., et al.: J. Med. Chem., 52, 5990 (2009); Bell, H., et al.: Am. J. Physiol., 297, R370 (2009); Maresca, A., et al.: Bioorg. Med. Chem. Lett., 19, 4929 (2009); Liu, Y., et al.: Anal. Bioanal. Chem., 395, 591 (2009)<br></p>

<p>Applications D-Cysteine is a strong inhibitor of Escherichia coli growth and also functions to provide inorganic sulfates for the sulfation of xenobiotics. D-Cysteine is a non-physiological isomer of L-Cysteine (C995000), and is not involved in protein or glutathione synthesis.<br>References Glazenburg, E., et al.: Biochem. Pharm., 33, 625 (1984); Klassen, C. &amp; Boles, J.: FASEB J., 11, 404 (1997); Soutourina, J., et al.: J. Biol. Chem., 276, 40864 (2001);<br></p>

<p>Applications Selenourea is an excellent antiradical agent and biomimetic catalysts of glutathione peroxidase for the scavenging of hydrogen peroxide. It is also potent and selective cytotoxic agent against cancer cells. Chalcogenizing agent.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Marset, A., et al.: Future Med. Chem., 8, 2185-2195 (2016); Tulenin, S. S., et al.: Russ. J. Inorg. Chem., 61, 488-495 (2016)<br></p>

<p>Applications (+)-MK 801 Hydrogen Maleate acts as an NMDA receptor antagonist. It is selective and potent, but noncompetitive, used in various ischemia treatments.<br>References Ma, J. et al.: Hippocamp., 22, 2208 (2012); Cao, Z. et al.: Toxicol. Sci., 130, 362 (2012);<br></p>

<p>Applications Metabolite fingerprinting in transgenic Nicotiana tabacum altered by the Escherichia coli glutamate dehydrogenase gene. A synthetic intermediate in the preparation of CNS depressants.<br>References Mungur, R., et al.: J. Biomed. Biotechnol., 2, 198 (2005), Young, J., et al.: Bioorg. Med. Chem. Lett., 17, 5310 (2007),<br></p>

<p>Applications A uricosuric drug. It is used to effectively to control hyperuricemia in renal transplantation.<br>References Lemieux, G. et al.: Am. J. Physiol., 224, 1440 (1973); Zoellner, N. et al.: Arzneim.-Forsch., 21, 1500 (1971); Perez-Ruiz, F. et al.: Nephrol. Dial. Transplant., 18, 603 (2003);<br></p>

<p>Applications N-Methylcaprolactam is a reagent that is used in the synthesis of 3-Chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone-13C5, which is a chlorinated furanone that accounts for more of the mutagenic activity of drinking water than any other disinfection byproduct.<br></p>

<p>Applications Amifostine Trihydrate is a widely used cytoprotective and radio-protective agent.<br>References Adibhatla K.S., et al. Novel method of manufacture of high purity Amifostine trihydrate. Indian Pat. Appl. IN 2005CH01592 A 20080125. Jan 25, 2008<br></p>

<p>Applications Magnesium Monoperoxyphthalic Acid Hexahydrate is used as an oxidant in various synthetic reactions. For example: it is a mild and efficient oxidant for the synthesis of selenones which are useful synthetic intermediates in the synthesis of different heterocyclic compounds.<br>References Temperini, A., et al.: Beilstein J. Org. Chem., 10, 1267 (2014); Salvador, J.A.R., et al.: Beilstein J. Org. Chem., 8, 164 (2012); Carvalho, J.F.S., et al.: Tetrahedron, 65, 2773 (2009)<br></p>

<p>Applications Magnesium Chloride Hexahydrate is used in magnesium replacement therapy for those deficient in magnesium. Effective anaesthetic for cephalopods.<br>References Iezhitsa, I. et al.: Nutr. Neurosci., 14, 10 (2011); Culloty, S. et al.: Aquaculture., 107, 249 (1992);<br></p>

<p>Applications An antineoplastic.<br>References Hertel, L.W., et al.: Cancer Res., 50, 4417 (1990), Abbruzzese, J.L., et al.: J. Clin. Oncol., 9, 491 (1991), Ruiz, V.W.T., et al.: Biochem. Pharmacol., 46, 762 (1993),<br></p>

<p>Applications Drug used in the treatment and prevention of cardiovascular diseases.<br>References Lo, R., et al.: Curr. Clin. Pharmacol., 3, 156 (2008), Ghali, J., et al.: Cardiol., 111, 147 (2008),<br></p>