Padrões Farmacêuticas
Os padrões farmacêuticos são um conjunto abrangente de materiais de referência essenciais para garantir a segurança, eficácia e qualidade dos produtos farmacêuticos. Esta categoria inclui padrões para ingredientes farmacêuticos ativos (APIs), que são os componentes principais responsáveis pelos efeitos terapêuticos. Além disso, abrange compostos e metabólitos relevantes tanto para a indústria farmacêutica quanto veterinária, fornecendo referências para a medição e análise precisa dessas substâncias. Padrões de controle de nitrosaminas são cruciais para detectar e mitigar nitrosaminas potencialmente prejudiciais em formulações de medicamentos. Padrões de toxicologia ajudam a avaliar a segurança e os potenciais efeitos adversos de compostos farmacêuticos. Além disso, padrões de ativadores e inibidores de enzimas são vitais para pesquisa e desenvolvimento, permitindo estudos precisos de vias bioquímicas e mecanismos de ação de medicamentos. Esses padrões farmacêuticos são ferramentas indispensáveis para conformidade regulatória, controle de qualidade e pesquisa, garantindo que os produtos farmacêuticos atendam a rigorosos critérios de segurança e eficácia.
Subcategorias de "Padrões Farmacêuticas"
- APIs para pesquisa e impurezas(273.774 produtos)
- Activadores e Inibidores de Enzimas(2.827 produtos)
- Nitrosaminas(2.606 produtos)
- Compostos e metabolitos farmacêuticos e veterinários(2.613 produtos)
- Toxicologia(13.652 produtos)
Foram encontrados 7836 produtos de "Padrões Farmacêuticas"
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α-Citral
CAS:<p>Applications α-Citral is an intermediate in the synthesis of 4,8-Dimethyl-1,3(E),7-nonatriene (D475810), which is a volatile compound released by corn plants in response to predation.<br>References Alborn, H,T,. et al.: Science, 276, 945 (1997)<br></p>Fórmula:C10H16OCor e Forma:Colourless To Light YellowPeso molecular:152.24Hydroxy Urea-13C,15N2
CAS:Produto Controlado<p>Applications Labelled Hydroxyurea. An anti-neoplastic - inhibits ribonucleoside reductase and DNA replication. A potential therapy for sickle cell anemia which involves the nitrosylation of sickle cell hemoglobin. Horseradish peroxidase catalyzes nitric oxide formation from hydroxyurea in the presence of hydrogen peroxide.<br>References Ratcliffe, W., et al.: Lancet, 339, 164 (1992), Roodman, G., et al.: Cancer, 80, 1557 (1997), Horwitz, M., et al.: J. Clin. Endocrinol. Metab., 2003, 88, 1603 (2003),<br></p>Fórmula:CH4N2O2Cor e Forma:Off White SolidPeso molecular:79.03N-Acetyl-L-tyrosine
CAS:Produto Controlado<p>Applications N-Acetyl-L-tyrosine is an analogue of L-tyrosine which stimulate the transport of L-Tyr, mainly by the ASC system.<br>References Jara, J. et al.: Melanoma Res., 1, 15 (1991),<br></p>Fórmula:C11H13NO4Cor e Forma:Off-WhitePeso molecular:223.23Cinnamic Acid
CAS:Produto Controlado<p>Applications Cinnamic Acid is rac-form of trans-Cinnamic Acid (P336185) which is used in the synthesis of amides and esters through coupling reactions involving carboxylic acids and amines and N-methylation of amides and O-methylation of carboxylic acids.<br>References Kunishima, M. et al.: Tetrahedron, 55, 13159 (1999); Xia, Q. et al.: Org. Lett., 15, 3326 (2013);<br></p>Fórmula:C9H8O2Cor e Forma:White To Off-WhitePeso molecular:148.1593-Cysteinylacetaminophen-D5 (major), Trifluoroacetic Acid Salt
CAS:Produto Controlado<p>Applications 3-Cysteinylacetaminophen-D5 (major), Trifluoroacetic Acid Salt is deuterium labeled 3-Cysteinylacetaminophen Trifluoroacetic Acid Salt (C994750), which is a metabolite of Acetaminophen (A161220), an analgesic and antipyretic agent used as a pain reliever to treat headache, muscle aches, and arthritis (1,2,3).Minimum isotopic incorporation d-3, no d-0 present. A representative lot has 64% isotopic incorporation at the 6-position, 89% at the 4-position.<br>References (1) McGill, M. R. and Jaeschke, H. Pharm Res. 30, 2174 (2013)(2) Fairbrother, J.E., et al.: Anal. Profiles Drug Subs., 3, 1 (1974) (3) Hinson, J.A., et al.: Rev. Biochem. Toxicol., 2, 103 (1980)<br></p>Fórmula:C11H9D5N2O4S•C2HF3O2Cor e Forma:NeatPeso molecular:389.36(4-Chloro-2-methylphenoxy-2,3,5-d3)acetic Acid
CAS:Produto Controlado<p>Applications Labelled derivative of (4-Chloro-2-methylphenoxy)acetic Acid (C369470).(4-Chloro-2-methylphenoxy)acetic Acid is a herbicide.Environmental toxin on US EPA Toxic Release Inventory list (TRI) list.<br>References Elliott, B., et al.: Mutagenesis, 20, 3 (2005); Pfleeger, T., et al.; Environmental Toxicology and Chemistry 30, 455 (2010);<br></p>Fórmula:C92H3H6ClO3Cor e Forma:White To Off-WhitePeso molecular:203.64Isopilocarpic Acid Sodium Salt
CAS:Produto Controlado<p>Impurity Pilocarpine Hydrochloride EP Impurity C<br>Stability Hygroscopic<br>Applications Isopilocarpic Acid is a degradation product of Pilocarpine (P441500).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Szepesi, G. et al.: Pharmazie, 38, 94 (1983); Bundgaard, H. et al.: Int. J. Pharmac., 10, 281 (1982);<br></p>Fórmula:C11H17N2O3·NaCor e Forma:WhitePeso molecular:248.252,3-Dihydroxy-1,4-naphthoquinone
CAS:Produto Controlado<p>Applications 2,3-dihydroxynaphthoquinone (cas# 605-37-8) is a useful research chemical.<br></p>Fórmula:C10H6O4Cor e Forma:NeatPeso molecular:190.151-Naphthylhydrazine
CAS:Produto Controlado<p>Applications 1-Naphthylhydrazine (cas# 2243-55-2) is a useful research chemical.<br></p>Fórmula:C10H10N2Cor e Forma:NeatPeso molecular:158.23-Hydroxy-2-naphthoic acid
CAS:Produto Controlado<p>Applications 3-Hydroxy-2-naphthoic acid<br></p>Fórmula:C11H8O3Cor e Forma:NeatPeso molecular:188.18Isovaleryl L-Carnitine-d9 Chloride
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Isovaleryl L-Carnitine-d9 Chloride is labelled Isovaleryl L-Carnitine Chloride (I917580) which is used to prepare carnitine benzyl esters as neuroprotectant prodrugs.<br>References Gong, X., et al.: J. Chem. Res., 6, 327 (2008)<br></p>Fórmula:C12H15D9ClNO4Cor e Forma:NeatPeso molecular:290.831-Nitropiperazine
CAS:Produto Controlado<p>Applications A nitro substituted piperazine.<br></p>Fórmula:C4H9N3O2Cor e Forma:NeatPeso molecular:131.13apo-Ipratropium Bromide
CAS:<p>Applications apo-Ipratropium Bromide is an intermediate used in the preparation of quaternary salts of alkaloids.<br>References Ivanov, V., et al.: Farmatsiya17, 18 (1967)<br></p>Fórmula:C20H28NO2·BrCor e Forma:NeatPeso molecular:394.34Calcium Chloride Hydrate
CAS:<p>Applications Calcium Chloride Dihydrate is used in the preparation of bisphosphonates used in attacking cancer cells.<br>References Liu, D. et al.: Chem. Comm., 48, 2668 (2012);<br></p>Fórmula:Ca·2Cl·2H2OCor e Forma:NeatPeso molecular:147.015-Hydroxycytosine
CAS:Produto Controlado<p>Applications 5-Hydroxycytosine, is been identified as an anomalous base of phage H-17 DNA. It is also a monosubstituted cytosine, as nucleotide-base antimetabolite-type potential anticarcinogen.<br>References Khromov, I. S. Doklady Akademii Nauk SSSR, 240, 1486 (1978); Ladik, J., et al.: Magyar Kemiai Folyoirat, 76, 589 (1970);<br></p>Fórmula:C4H5N3O2Cor e Forma:NeatPeso molecular:127.103,7,4'-Trihydroxyflavone
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 3,7,4'-Trihydroxyflavone (cas# 2034-65-3) is a useful research chemical.<br></p>Fórmula:C15H10O5Cor e Forma:NeatPeso molecular:270.24Dihydro Ferulic Acid Methyl Ester
CAS:Produto Controlado<p>Applications A protected caffeine metabolite with high antioxidant activity. It is a very sensitive biomarker for the consumption of relatively small amount of coffee.<br>References Buchanan, C., et al.: J. Sci. Food Agric., 71, 459 (1996), Andreasen, M., et al.: J. Agric. Food Chem., 49, 5679 (2001), Poquet, L., et al.: Drug Metab. Dispos., 36, 190 (2008),<br></p>Fórmula:C11H14O4Cor e Forma:NeatPeso molecular:210.232,3-Diketogulonic Acid Potassium Salt (Technical Grade)
CAS:<p>Stability Temperature Sensitive<br>Applications 2,3-Diketogulonic Acid Potassium Salt is an intermediate in biodegradation of Ascorbic Acid (A786990).<br>References Kagawa, Y.: J. Biochem., 51, 134 (1962); Otsuka, M., et al.: Agric. Biol. Chem., 50, 531 (1986);<br></p>Fórmula:C6H7O7·KCor e Forma:NeatPeso molecular:230.212-Methylnaphthalene-D10
CAS:Produto Controlado<p>Applications 2-Methylnaphthalene-D10 is a labelled analogue of 2-Methylnaphthalene (M323130). 2-Methylnaphthalene is a polycyclic aromatic hydrocarbon (PAH) that has been used as an indicator of smoke exposure in food and packaging materials.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Johnston, J.J., et. al.: J. Agr. Food Chem., 42, 1954 (1994)<br></p>Fórmula:C112H10Cor e Forma:NeatPeso molecular:152.263,3'-di-tert-Butyl-5,5'-dimethoxybiphenyl-2,2'-diol
CAS:Produto Controlado<p>Applications 3,3'-di-tert-butyl-5,5'-dimethoxybiphenyl-2,2'-diol (cas# 14078-41-2) is a useful research chemical.<br></p>Fórmula:C22H30O4Cor e Forma:Light OrangePeso molecular:358.471Phosphoric Acid Tris(3-methylphenyl) Ester
CAS:Produto Controlado<p>Applications Phosphoric Acid Tris(3-methylphenyl) Esteris a human urinary organophosphate flame retardant metabolite. It is also used to study properties of supercooled liquids.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Schindler, B., et al.: J. Chromat. B, 877, 375 (2009); Heuberger, G., et al.: J. Phys. Chem., 100, 15255 (1996); Blochowicz, T., et al.: J. Chem. Phys., 118, 7544 (2003)<br></p>Fórmula:C21H21O4PCor e Forma:Light YellowPeso molecular:368.36Carboxymethyl Cellulose Ether Sodium Salt
CAS:Produto Controlado<p>Applications Carboxymethyl Cellulose Ether is used as a thickener to enhance rigidity and composition of pharmaceutical compounds as well as the stability of electrode slurries in composite electrodes. Also provides ion-exchange for chromotography media.<br>References Salerno, C. et al.: AAPS PharmSciTech., 11, 986 (2010); Porcher, W. et al. J. Electrochem. Soc., 156, A133 (2009); Wang, H. et al.: Biochem. Biophys. Res. Comm., 342, 349 (2006);<br></p>Fórmula:C2H4O3•xUnspecified•xNaCor e Forma:Neat4-Formylbenzoic Acid Methyl Ester
CAS:Produto Controlado<p>Applications 4-Formylbenzoic Acid Methyl Ester is a benzoic acid derivative with antioxidant activity.<br>References Conde, E. et al.: Food Chem., 114, 806 (2009);<br></p>Fórmula:C9H8O3Cor e Forma:NeatPeso molecular:164.161-Naphthyl Acetate
CAS:Produto Controlado<p>Applications 1-Naphthyl Acetate (cas# 830-81-9) is a useful research chemical.<br></p>Fórmula:C12H10O2Cor e Forma:NeatPeso molecular:186.207Phosphoric Acid Tris(4-methylphenyl) Ester
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Phosphoric Acid Tris(4-methylphenyl) Ester is a human urinary organophosphate flame retardant metabolite.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Schindler, B., et al.: J. Chromat. B, 877, 375 (2009)<br></p>Fórmula:C21H21O4PCor e Forma:Off-WhitePeso molecular:368.36(5-Chloro-2,1,3-benzothiadiazol-4-yl)-carbamimidothioic Acid Methyl Ester Hydriodide Salt
CAS:Produto Controlado<p>Applications Tizanidine (T449500) intermediate.<br></p>Fórmula:C8H8ClIN4S2Cor e Forma:NeatPeso molecular:386.66trans-Hydroxy Glimepiride
CAS:Produto Controlado<p>Applications An active metabolite of Glimepiride.<br>References Muller, G., et al.: Diabetes, 42, 1852 (1993), Kramer, W., et al.: Biochem. Biophys. Acta, 119, 278 (1994),<br></p>Fórmula:C24H34N4O6SCor e Forma:NeatPeso molecular:506.62Urea-urethane Compound (~85%)
CAS:Produto Controlado<p>Applications Urea-urethane Compound is a reaction product of 4,4'-sulfonylbis[benzenamine] and 2,4-TDI.<br></p>Fórmula:C42H36N6O8SPureza:~80%Cor e Forma:NeatPeso molecular:784.844-(3-Bromo-4-oxobutyl)benzoic Acid Methyl Ester
CAS:Produto Controlado<p>Applications 4-(3-Bromo-4-oxobutyl)benzoic Acid Methyl Ester is used as a reagent in the synthesis of furoxanoxyalkyl esters of pemetrexed as antifolates and nitric oxide donors for use as anticancer agents and their activities against four human cancer cell lines.<br>References Min, T., et al.: Med. Chem. Res., 18, 495 (2009); Barnett, C.J., et al.: Org. Process Res. Dev., 3, 184 (1999)<br></p>Fórmula:C12H13BrO3Cor e Forma:NeatPeso molecular:285.138-Amino-5-[(4-hydroxyphenyl)amino]-2-naphthalenesulfonic Acid
CAS:Produto Controlado<p>Applications A diamino substituted nathalenesulfonic acid derivative.<br></p>Fórmula:C16H14N2O4SCor e Forma:NeatPeso molecular:330.358Igepal CO-520
CAS:<p>Applications Igepal is a nonionic surfactant.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Sedgqwick, M. et al.: Langmuir, 25, 5496 (2009);<br></p>Fórmula:(C2H4O)n·C15H24OCor e Forma:ColourlessBetamethasone 17-Propionate
CAS:Produto Controlado<p>Impurity Clobetasol Propionate EP Impurity A / Betamethasone Dipropionate EP Impurity B<br>Applications Betamethasone 17-Propionate (Clobetasol Propionate EP Impurity A) is a degradation product of Betamethasone. Glucocorticoid.<br>References Andersson, P., et al.: J. Pharm. Pharmacol., 36, 763 (1984), Wurthwein, G., et al.: Biopharm. Drug Dispos., 11, 381 (1990), Samtani, M., et al.: J. Pharm. Sci., 93, 726 (2004), Samtani, M., et al.: Drug Metab. Dispos., 33, 1124 (2005),<br></p>Fórmula:C25H33FO6Cor e Forma:Off-WhitePeso molecular:448.52Higenamine Hydrobromide Salt
CAS:Produto Controlado<p>Applications Higenamine acts through inhibition of middle cerebral artery occlusion (MCAO)-mediated HMGB1 release in vivo. Useful towards ischemic injuries.<br>References Ha, Y. et al.: Apoptosis., 17, 463 (2012);<br></p>Fórmula:C16H18BrNO3Cor e Forma:Off-WhitePeso molecular:352.22N-Formyl Varenicline
CAS:Produto Controlado<p>Applications A metabolite of Varenicline. Metabolite M5.<br>References Dow, J., et al.: Drug Metab. Dispos., 22, 738 (1994), Toide, K., et al.: Biochem. Pharmacol., 67, 1269 (2004), Coe, J., et al.: J. Med. Chem., 48, 3474 (2005), Doll, R., et al.: Br. J. Cancer, 92, 426 (2005),<br></p>Fórmula:C14H13N3OCor e Forma:NeatPeso molecular:239.272-Hydrazino Adenosine
CAS:Produto Controlado<p>Stability Moisture Sensitive<br>Applications A useful synthetic intermediate for making potent and selective coronary vasodilators.<br>References Niiya, K., et al.: J. Med. Chem., 35, 4557 (1992)<br></p>Fórmula:C10H15N7O4Cor e Forma:NeatPeso molecular:297.27Guanosine 5'-Diphosphate Disodium Salt
CAS:Produto Controlado<p>Applications Guanosine 5'-diphosphate disodium salt (cas# 7415-69-2) is a useful research chemical.<br></p>Fórmula:C10H13N5Na2O11P2Pureza:>85%Cor e Forma:NeatPeso molecular:487.168-anti-Ipratropium Bromide
CAS:Produto Controlado<p>Impurity Ipratropium EP Impurity B<br>Applications 8-anti-Ipratropium Bromide (Ipratropium EP Impurity B) is a related compound to Ipratropium Bromide (I740500), nonselective muscarinic acetylcholine receptor antagonist; bronchodilator.<br>References Groeben, H., et al.: Anesthesiology, 85, 867 (1996), Haddad, et al.: Br. J. Pharmacol., 127, 413 (1999), Barnes, P. J., et al.: Chest, 117, 63S (2000),<br></p>Fórmula:C20H30NO3·BrCor e Forma:NeatPeso molecular:412.36Carbimazole
CAS:<p>Applications Carbimazole, a prodrug of Methimazole (M260300), is used in the treatment of hyperthyroidism.<br>References Marchant, B., et al.: J. Clin. Endocrinol. Metab., 45, 1187 (1977), Johnsson, E., et al.: Lancet, 350, 1520 (1997),<br></p>Fórmula:C7H10N2O2SCor e Forma:NeatPeso molecular:186.23Selenosulfuric Acid Dipotassium Salt, Technical Grade
CAS:Produto Controlado<p>Applications Selenosulfuric Acid Disodium Salt is used in the synthesis of CdSe photocatalysts with enhanced photocatalytic ativitys. Possible application towards industrial wastewater treatment and pollutant removal.<br>References Lim, C. et al.: Bull. Korean Chem Soc., 32, 1657 (2011);<br></p>Fórmula:K2O3SSeCor e Forma:NeatPeso molecular:237.22(-)-2-Methyl Isoborneol-d3
CAS:Produto Controlado<p>Applications Isotope labelled (-)-2-Methylisoborneol (M314000), which is a derivative of Camphor (1) (C165805). (-)-2-Methylisoborneol is a flavor component of Robusta coffee responsible for the off-flavour aroma (2). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA). Environmental contaminants; Food contaminants.<br>References 1. Money T. Nat Prod Rep. 1985 Jun;2(3):253-89.2. Blank I et al.: J Agric Food Chem. 2002 Jul 31;50(16):4653-6.<br></p>Fórmula:C112H3H17OCor e Forma:NeatPeso molecular:171.29Pranoprofen
CAS:Produto Controlado<p>Applications Pranoprofen is an anti-inflammatory used in ophthalmology.<br>References Ayaki, M., et al.: Biocont. Sci., 15, 97 (2010); Lee, X., et al.: For. Toxicol., 28, 96 (2010);<br></p>Fórmula:C15H13NO3Cor e Forma:Off White CrystallinePeso molecular:255.27Daidzein 7-β-D-Glucuronide 4’-Sulfate Disodium Salt
CAS:<p>Stability Very Hygroscopic<br>Applications Mixed conjugate of dietary phytoestrogen.<br>References Adlercreutz, H;., et al.: J. Steroid Mol. Biol., 52, 97 (1995), Kinjo, J., et al.: Biol. Pharm. Bull., 27, 185 (2004),<br></p>Fórmula:C21H16Na2O13SCor e Forma:NeatPeso molecular:554.394-Acetamido Antipyrine-d3
CAS:Produto Controlado<p>Applications A labelled metabolite of Metamizol. Metabolism of Metamizol in early stages of the incubated hen's egg.<br>References Brunstrom, B., et al.: Arch. Toxicol., 57, 69 (1985), Lorr, N., et al.: Biochem. Pharmacol., 36, 3059 (1987), Niwa, T., et al.: Xenobiotica, 29, 187 (1999), Niwa, T., et al.: Biol. Pharm. Bull., 23, 498 (2000),<br></p>Fórmula:C132H3H12N3O2Cor e Forma:NeatPeso molecular:248.30Dimefline Hydrochloride
CAS:Produto Controlado<p>Applications Dimefline is a new respiratory stimulant drug.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Edwards, J.M., et al.: J. Nat. Prod., 42, 85 (1979), Setnikar, I., et al.: Arzneim.-Forsch., 11 1109 (1961),<br></p>Fórmula:C20H21NO3·HClCor e Forma:NeatPeso molecular:359.853-(4-Chlorophenyl)glutaric Anhydride
CAS:Produto Controlado<p>Stability Moisture Sensitive<br>Applications 3-(4-Chlorophenyl)glutaric Anhydride (cas# 53911-68-5) is a compound useful in organic synthesis.<br></p>Fórmula:C11H9ClO3Cor e Forma:Off-WhitePeso molecular:224.64O-Desmethyl Astemizole
CAS:Produto Controlado<p>Applications A metabolite of Astemizole.<br>References Nagata, K., et al.: J. Biol. Chem., 268, 24720 (1993), Benton, R., et al.: Clin. Pharmacol. Ther., 59, 383 (1996), Hashizume, T., et al.: Drug Metab. Dispos., 26, 566 (1998), Scarborough, P., et al.: Drug Metab. Rev., 31, 205 (1999),<br></p>Fórmula:C27H29FN4O·ClHCor e Forma:NeatPeso molecular:481.00Atorvastatin Lactam Sodium Salt Impurity
CAS:<p>Impurity Atorvastatin Pyrrolidone Analog (USP)<br>Stability Light Sensitive<br>Applications A photodegradation product of Atorvastatin (a cyclic impurity of Atorvastatin). Atorvastatin Pyrrolidone Analog (USP).<br>References Roger, D., et al.: Clin. Exp. Dermatol., 19, 88 (1994), Cosa, G., et al.: Photochem. Photobiol., 80, 159 (2004), Kerwin, B., et al.: J. Pharm. Sci., 96, 1468 (2007),<br></p>Fórmula:C33H34FN2O6·NaCor e Forma:WhitePeso molecular:596.624-Hydroxy-N-desbutyl Bupivacaine
CAS:Produto Controlado<p>Applications Bupivacaine metabolite.<br>References Goehl, T. J. et al.: Xenobiotica 3, 761 (1973)<br></p>Fórmula:C14H20N2O2Cor e Forma:NeatPeso molecular:248.325-Iodovanillic Acid
CAS:Produto Controlado<p>Applications 5-Iodovanillic acid (cas# 98554-57-5) is a useful research chemical.<br></p>Fórmula:C8H7IO4Cor e Forma:Off-WhitePeso molecular:294.04Tetrachloroauric Acid
CAS:Produto Controlado<p>Applications Tetrachloroauric Acid, is used for the recovery, concentrating, purification, and analytical determinations of gold. It is the precursor used in the purification of gold by electrolysis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mironov, I. V., et al.: Russian J. Inorg. Chem., 57, 610 (2012); Feather, A., et al.: J. Southern Africa Inst. mining Metal., 169 (1997);<br></p>Fórmula:AuCl3·ClHCor e Forma:NeatPeso molecular:339.795-Amino-1-naphthalenesulfonamide Hydrochloride
CAS:Produto Controlado<p>Applications 5-Amino-1-naphthalenesulfonamide Hydrochloride (cas# 1215328-08-7) is a compound useful in organic synthesis.<br></p>Fórmula:C10H11ClN2O2SCor e Forma:Off-White To GreyPeso molecular:258.72Abiraterone Ethyl Ether
CAS:Produto Controlado<p>Applications Abiraterone Ethyl Ether is an impurity of Abiraterone (A108490), a steroidal cytochrome P 450 17α-hydroxylase-17,20-lyase inhibitor (CYP17), is currently undergoing phase II clinical trials as a potential drug for the treatment of androgen-dependent prostate cancer.<br>References Denis, L., et al.: Cancer, 72, 3888 (1993); Potter, G.A., et al.: J. Med. Chem., 38, 2463 (1995); Denmeade, S., et al.: Nat. Rev., 2, 389(2002); Scher, H., et al.: J. Clin. Oncol., 23, 8253 (2005)<br></p>Fórmula:C26H35NOCor e Forma:NeatPeso molecular:377.569-Deschloro-9-bromo Beclomethasone Dipropionate
CAS:Produto Controlado<p>Impurity Beclomethasone Dipropionate EP Impurity D<br>Applications 9-Deschloro-9-bromo Beclomethasone Dipropionate (Beclomethasone Dipropionate EP Impurity D) is an impurity of Beclomethasone Dipropionate (B131030).<br>References Shou, M. et al.: J. Pharmac. Biomed. Anal., 50, 356 (2009); Johnston, S. et al.: J. Chrom. Sci., 48, 733 (2010);<br></p>Fórmula:C28H37BrO7Cor e Forma:NeatPeso molecular:565.49Methyl-1-naphthalenemethylamine
CAS:<p>Impurity Terbinafine EP Impurity A; Terbinafine BP Impurity A; Terbinafine USP Related Compound A<br>Applications Terbinafine EP Impurity A. Terbinafine BP Impurity A. Terbinafine USP Related Compound A<br></p>Fórmula:C12H13NCor e Forma:OrangePeso molecular:171.245'-Cholesteryl-TEG Phosphoramidite
CAS:Produto Controlado<p>Applications 5’-Cholesteryl-TEG Phosphoramidite is used in the synthesis of immunostimulatory oligonucleotides for in vivo cell modification for immunotherapy.<br>References Liu, H. et al.: Angew. Chem. Int. Ed., 50, 7052 (2011);<br></p>Fórmula:C46H82N3O7PCor e Forma:NeatPeso molecular:820.13Diltiazem-d3 Hydrochloride
CAS:Produto Controlado<p>Applications Labelled Diltiazem (D460620). A calcium channel blocher with vasodilating activity. Antianginal; antihypertensive; antiarrhythmic (class IV).<br>References Sato, et al.: Arzneim.-Forsch., 21, 1338 (1971), Smirnov, S.R.: Eur. J. Pharmacol., 360, 81 (1998), Hansson, L., et al.: Lancet, 356, 359 (2000),<br></p>Fórmula:C22H24D3ClN2O4SCor e Forma:NeatPeso molecular:454.0Theobromine-d6
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications A labelled metabolite of Caffeine.<br>References Suto, M., et al.: Anticancer Drug Des., 6, 107 (1991), Burkart, V., et al.: Nat. Med., 5, 314 (1999), Hassa, P., et al.: J. Biol. Chem., 278, 45145 2003), Veres, B., et al.: J. Pharmacol. Exp. Ther., 310, 247(2004),<br></p>Fórmula:C72H6H2N4O2Cor e Forma:WhitePeso molecular:186.205-Oxo Atorvastatin
CAS:<p>Applications Atorvastatin Derivative<br></p>Fórmula:C33H33FN2O5Cor e Forma:NeatPeso molecular:556.62trans-β-Farnesene
CAS:Produto Controlado<p>Applications trans-β-Farnesene is a sesquiterpene natural product made my different plants to repel pest aphid species.<br>References Bruce, T., et al.: Pest Manag. Sci., 61, 1115 (2005);<br></p>Fórmula:C15H24Cor e Forma:NeatPeso molecular:204.35N-2 Trityl Olmesartan Medoxomil
CAS:<p>Impurity Olmesartan Medoxomil EP Impurity D<br>Applications Olmesartan medoxomil intermediate.<br>References Birkenhager, W., et al.: J. Hypertens, 17, 873 (1999), Whittaker, A., et al.: Br. J. Cardiol., 12, 125 (2005),<br></p>Fórmula:C48H44N6O6Cor e Forma:White To Light YellowPeso molecular:800.90Naphthacene
CAS:Produto Controlado<p>Applications Naphthacene is a polycyclic aromatic hydrocarbon. Naphthacene is often used as a molecular organic semiconductor in organic field-effect transistors and organic light-emitting diodes. Naphthacene is also used in various applications involving the enhancement of photocurrent.<br>References Cnops, K., et al.: Applied. Phy. Letters., 101, 143301 (2012); Ooi, Z.E., Applied. Phy. Letters., 100, 93302 (2012);<br></p>Fórmula:C18H12Pureza:>80%Cor e Forma:NeatPeso molecular:228.29(E)-4-Formylcinnamic Acid Methyl Ester
CAS:Produto Controlado<p>Applications Cinnamic Acid derivative<br>References Sato, M., et al.: Chem. Pharm. Bull., 42, 521 (1994), Remiszewski, S., et al.: J. Med. Chem., 46, 4609 (2003),<br></p>Fórmula:C11H10O3Cor e Forma:NeatPeso molecular:190.2trans-Hydroxy Perhexiline (Mixture of Diastereomers)
CAS:Produto ControladoFórmula:C19H35NOCor e Forma:NeatPeso molecular:293.49D,L-N,N-Didesmethyl-O-desmethyl Venlafaxine Hydrochloride
CAS:<p>Applications A metabolite of Venlafaxine.<br></p>Fórmula:C14H22ClNO2Cor e Forma:NeatPeso molecular:271.781,2-Dihydro-1,1,6-trimethylnaphthalene (>80%)
CAS:Produto Controlado<p>Applications 1,2-Dihydro-1,1,6-trimethyl-naphthalene is responsible for a "kerosene note" or "petrol" aromas in aged Riesling wines.<br>References Sacks, G., et al.: J. Agri. Food Chem., 60, 2998 (2012); Winterhalter, P., et al.: ACS Symposium Series, 1134, 125 (2013)<br></p>Fórmula:C13H16Pureza:>80%Cor e Forma:Colourless OilyPeso molecular:172.271,2-Dihydro Desoxymetasone
CAS:Produto Controlado<p>Applications A metabolite of Desoxymetasone (D296970).<br>References Schriks, M., et al.: Environ. Sci. Technol., 44, 4766 (2010), Baeck, M., et al.: Eur. J. Dermatol., 20, 102 (2010), Lee, P., et al.: Bioorg. Med. Chem. Lett., 20, 69 (2010),<br></p>Fórmula:C22H31FO4Cor e Forma:NeatPeso molecular:378.48Adenosine
CAS:<p>Applications Adenosine is a nucleotide.<br>References Long, X., et al.: J. Pharmacol. Exper. Ther., 335, 781 (2010); Ham, M., et al.: J. Pharmacol. Exper. Ther., 335, 607 (2010);<br></p>Fórmula:C10H13N5O4Cor e Forma:NeatPeso molecular:267.24Simvastatin Dimer Impurity
CAS:Fórmula:C50H76O10Cor e Forma:White To Light YellowPeso molecular:837.13Bis(4-cyanophenyl)methanol
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications A metabolite of Letrozole.<br>References Koyama, E., et al.: Ther. Drug Monit., 15, 224 (1993), Pfister, C., et al.: J. Pharm. Sci., 83, 520 (1994), Vander H.Y., et al.: J. Pharm. Biomed. Anal., 24, 723 (2001), Cohen, M., et al.: Clin. Cancer Res., 8, 665 (2002),<br></p>Fórmula:C15H10N2OCor e Forma:NeatPeso molecular:234.25Mosapride Citric Amide Disodium Salt
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Disodium salt of Mosapride (M731000) derivative.<br>References Yoshida, N., et al.: Arch. Int. Pharmacodyn. Ther., 300, 51 (1989), Yatera, S., et al.: Japan. Pharmacol. Ther., 21, 21 (1993), Ruth, M., et al.: Aliment Pharmacol. Ther., 12, 35 (1998),<br></p>Fórmula:C27H29ClFN3Na2O9Cor e Forma:NeatPeso molecular:639.96epi Dienogest
Produto Controlado<p>Applications epi Dienogest, is metabolite of Dienogest (D441870), a derivative of 19-Nortestosterone, that in combination with estrogencan acts as oral contraceptive.<br>References Hubner, M., et al.: Arzneim.-Forsch., 30, 401 (1980), Spona, J., et al.: Contraception, 56, 185 (1997), Foster, R.H., et al.: Drugs, 56, 825 (1998),<br></p>Fórmula:C20H25NO2Cor e Forma:NeatPeso molecular:311.422-O-Desmethyl Cisapride
CAS:Produto Controlado<p>Applications Minor Cisapride (C496400) metabolite.<br>References Meuldermans, W., et al.; Drug Metab. Disposition, 16, 410 (1988), Lowry J., et al.; Clin. pharmacol. ther., 73, 209 (2003), Shao L., et al.: Bioorg. Med. Chem. Lett., 19, 5679 (2009),<br></p>Fórmula:C22H27ClFN3O4Cor e Forma:NeatPeso molecular:451.92N-Methylcytisine
CAS:<p>Applications N-Methylcytisine (cas# 486-86-2) is a compound useful in organic synthesis.<br></p>Fórmula:C12H16N2OCor e Forma:Off-WhitePeso molecular:204.27Nor Verapamil Hydrochloride
CAS:<p>Impurity Verapamil EP Impurity J HCl<br>Applications Nor Verapamil Hydrochloride (Verapamil EP Impurity J HCl) is a metabolite of Verapamil.<br>References Mutlib, A.E., et al.: The Journal of Pharm. & Exp. Therapeutics, 252, 2, 593 (1989)<br></p>Fórmula:C26H37ClN2O4Cor e Forma:WhitePeso molecular:477.04Desacetyl Rifampicin Quinone
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications Desacetyl Rifampicin Quinone is an impurity of Rifampicin (R508000).<br>References Wilson, W.L. et al.: J. Chrom., 144, 270 (1977);<br></p>Fórmula:C41H54N4O11Cor e Forma:NeatPeso molecular:778.89Betamethasone 21-Acetate 17-Propionate
CAS:<p>Impurity Betamethasone Dipropionate EP Impurity D<br>Applications Betamethasone 21-acetate-17-propionate (Betamethasone Dipropionate EP Impurity D) is a related compound of Betamethasone dipropionate (B327005).<br>References Grootveld, M., et al.: Biochem. Pharmacol., 37, 271 (1988), Chen, B., et al.: Steriods, 74, 30 (2009), Mikami, E., et al.: J. Pharm. Biomed. Anal., 28, 261 (2002),<br></p>Fórmula:C27H35FO7Cor e Forma:NeatPeso molecular:490.561Conduritol A
CAS:Produto Controlado<p>Applications Conduritol A (cas# 526-87-4) is a compound useful in organic synthesis.<br></p>Fórmula:C6H10O4Cor e Forma:NeatPeso molecular:146.14Pirenoxine
CAS:Produto Controlado<p>Applications Pirenoxine, is a medication used in the possible treatment and prevention of cataracts.<br>References Liao, J. H. et al.: Inorganic Chemistry. 50 (1): 365–377.<br></p>Fórmula:C16H8N2O5Cor e Forma:NeatPeso molecular:308.25(R)-α-Phellandrene
CAS:<p>Applications (R)-α-Phellandrene is a stereoisomer of Phellandrene, an alkaloid isolated from the Phellodrndron amurensis, which shows activity as an immunosuppressor agains tthe cellular immune response. Due to its pleasing aroma, it is commonly used in fragrances.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Mori, H.et al.: Planta. Med., 61, 45 (1995);<br></p>Fórmula:C10H16Cor e Forma:NeatPeso molecular:136.23(4-Bromophenyl)urea
CAS:<p>Applications (4-Bromophenyl)urea (cas# 1967-25-5) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C7H7N2OBrCor e Forma:Off-White To PurplePeso molecular:215.052-Hydroxy Atorvastatin Calcium Salt
CAS:Produto Controlado<p>Applications di(2-Hydroxy Atorvastatin) Calcium Salt is a metabolite of Atorvastatin Calcium Salt (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Kearney, A.S., et al.: Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al.: Clin. Ther., 18, 853 (1996); Whitfield, L.R., et al.: Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000)<br></p>Fórmula:C66H68CaF2N4O12Cor e Forma:White To YellowPeso molecular:1187.3516α-Hydroxy Estrone
CAS:<p>Impurity Estriol EP Impurity H<br>Applications 16α-Hydroxy Estrone (Estriol EP Impurity H) is a major metabolite of Estradiol.<br>References Fishman, H.G, et al.: Biochemistry, 8, 4304 (1969), Ryan, Sugar, J., et al.: J. Clin. Endocrinol. Metab., 50, 137 (1980), Numazawa, M., et al.: Steroids, 38, 149 (1981), Travis, R., et al.: Breast Cancer Res., 5, 239 (2003),<br></p>Fórmula:C18H22O3Cor e Forma:White To BeigePeso molecular:286.37Dabigatran Carboxamide Ethyl Ester
CAS:<p>Applications Dabigatran Carboxamide Ethyl Ester is an impurity of Dabigatran Etexilate Mesylate (D100150) which is a nonpeptide, direct thrombin inhibitor.<br>References Hauel, N., et al.: J. Med. Chem., 45, 1757 (2002); Mungall, D., et al.: Curr. Opin. Invest. Drugs, 3, 095 (2002); Stangier, J., et al.: J. Clin. Pharmacol., 45, 555 (2005)<br></p>Fórmula:C27H28N6O4Cor e Forma:Off-WhitePeso molecular:500.55Methyl 1-Naphthaleneacetate
CAS:<p>Applications Methyl 1-naphthaleneacetate (cas# 2876-78-0) is a useful research chemical.<br></p>Fórmula:C13H12O2Cor e Forma:NeatPeso molecular:200.234-Hydroxy Estradiol 1-N7-Guanine
CAS:Produto Controlado<p>Applications 4-Hydroxy Estradiol 1-N7-Guanine is an estrogen metabolite formed with DNA which can lead to the mutations that initiate breast, prostate, and other types of cancer. Estrogen-DNA depurinating adducts as biomarkers of cancer risk and their use in cancer detection and prevention.<br>References Chakravarti, D., et al.: Mutat. Res., 456, 17 (2000), Liehr, J., et al.: Endocr. Rev., 21, 4054 (2000), Chakravarti, D., et al.: Oncogene, 20, 7945 (2001), Cavalieri, E., et al.: Chem. Res. Toxicol., 14, 1041 (2002),<br></p>Fórmula:C23H27N5O4Cor e Forma:NeatPeso molecular:437.49N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine
CAS:Produto Controlado<p>Applications N2'-Deacetyl-N2'-[3-(methylthio)-1-oxopropyl]-maytansine is an active metabolite of Maytansine (M197940), inhibits in vitro polymerization of tubulin and is used in the treatment of advanced breast cancer.<br>References Remillard, S., et. al.: Science, 189, 1002 (1975); Prota, A.E., et. al.: P. Natl. Acad. Sci. USA, 111, 13817 (2014)<br></p>Fórmula:C36H50ClN3O10SPureza:>90%Cor e Forma:NeatPeso molecular:752.31N-(Methyl-d3)-4-phenylpyridinium Iodide
CAS:Produto Controlado<p>Applications A labelled dopaminergic neurotoxin; a selective cytostatic agent in small-cell lung cancer cell lines with neuroendocrine properties.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Marini, A.M. et al.: J, Nat. Cancer Inst., 84, 1582 (1992); Singh, M. et al.: Arch. Biochem. Biophys., 286, 138 (1991); Santiago, M. et al.: J. Neurosci. Meth., 108, 181 (2001);<br></p>Fórmula:C122H3H9N·ICor e Forma:NeatPeso molecular:300.15(4R,6S)-6-[(1E)-2-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester
CAS:Produto Controlado<p>Impurity Rosuvastatin EP Impurity F<br>Applications (4R,6S)-6-[(1E)-2-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetic Acid 1,1-Dimethylethyl Ester (Rosuvastatin EP Impurity F) is a Rosuvastatin (R700500) intermediate as HMG-CoA reductase inhibitor.<br>References Beck, et al.: J. Med. Chem., 33, 52 (1999),<br></p>Fórmula:C29H40FN3O6SCor e Forma:NeatPeso molecular:577.713-Ethyl Adenine-d5 (2% d0)
CAS:Produto Controlado<p>Applications 3-Ethyl Adenine-d5 (2% d0) (cas# 147028-85-1) is a compound useful in organic synthesis.<br></p>Fórmula:C72H5H4N5Cor e Forma:White To Off-WhitePeso molecular:168.211-(6-Amino-9H-purin-2-yl)-1H-pyrazole-4-carboxylic Acid Ethyl Ester (>85%)
CAS:Produto Controlado<p>Applications 1-(6-Amino-9H-purin-2-yl)-1H-pyrazole-4-carboxylic Acid Ethyl Ester is an intermediate in synthesizing 1-(6-Amino-9H-purin-2-yl)-N-methyl-1H-pyrazole-4-carboxamide (A629440), it is used in the synthetic preparation of regadenoson and intermediates by using cyclocondensation, amidation and condensation as the key steps.<br>References Chai, J.; et al.: Faming Zhuanli Shenqing. 14pp.Patent 2015 CODEN:CNXXEV<br></p>Fórmula:C11H11N7O2Pureza:>85%Cor e Forma:NeatPeso molecular:273.25α-Amylcinnamyl Alcohol
CAS:Produto Controlado<p>Applications Alpha-Amylcinnamyl Alcohol (cas# 101-85-9) is a useful research chemical.<br></p>Fórmula:C14H20OCor e Forma:NeatPeso molecular:204.31Juvenile Hormone B 3 (Mixture of Diastereomers), Technical Grade
CAS:Produto Controlado<p>Applications Juvenile Hormone B 3 is a sesquiterpenoid produced by the larval ring gland and adult corpus allatum (CA) of Drosophila melanogaster. Juvenile hormones regulate development, reproduction, diapause, and polyphenisms.<br>References Wang, Ch., et al.: Gen. Comp. Endocr., 176, 347 (2012); Bendena, W.G., et al.: Gen. Comp. Endocr., 172, 56 (2011); Wyatt, G., Davey, K.: Adv. Insect Physiol., 26, 1 (1996); Nijhout, H.: Insect Hormones (Princeton Univ. Press, Princeton) (1994)<br></p>Fórmula:C16H26O4Cor e Forma:NeatPeso molecular:282.38Cocamidopropyl Betaine (~30% aqueous solution)
CAS:<p>Applications Cocamidopropyl Betaine is a medium strength surfactant.<br></p>Fórmula:C19H38N2O3Cor e Forma:ColourlessPeso molecular:342.523'-(Trifluoromethyl)acetophenone Oxime
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications m-(Trifluoromethyl)acetophenone Oxime is a reactant in the synthesis of Trifloxystrobin (T778900) which is a broad-spectrum foliar fungicide used in plant protection.<br>References Chen, W., et al.: Huaxue Yanjiu, 25, 16 (2014); Margot, P. et al.: Bright. Crop Prot. Conf. Pest Dis., 2, 375 (1998); Karadimos, D.A. et al.: Crop Prot., 24, 23 (2005); Prom, L.K. et al.: Plant Dis., 87, 252 (2003);<br></p>Fórmula:C9H8F3NOCor e Forma:NeatPeso molecular:203.16Fulvestrant 9-Sulfone
CAS:Produto Controlado<p>Impurity Fulvestrant EP Impurity B<br>Applications A metabolite of Fulvestrant (F862500).<br>References Rao, P., et al.: J. Steroid Biochem., 25, 417 (1986), Wakeling, A., et al.: J. Steroid Biochem. Mol. Biol., 43, 173 (1992), DeFriend, D., et al.: Cancer Res., 54, 408 (1994),<br></p>Fórmula:C32H47F5O4SCor e Forma:NeatPeso molecular:622.77Succinyl Carnitine Chloride Salt
CAS:Produto Controlado<p>Stability Very Very Hygroscopic<br>Applications A metabolic intermediate of L-Carnitine.<br>References Huffman, K. et al.: Diab. Care, 32, 1678 (2009);<br></p>Fórmula:C11H20NO6ClCor e Forma:NeatPeso molecular:297.73
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