Padrões Farmacêuticas
Os padrões farmacêuticos são um conjunto abrangente de materiais de referência essenciais para garantir a segurança, eficácia e qualidade dos produtos farmacêuticos. Esta categoria inclui padrões para ingredientes farmacêuticos ativos (APIs), que são os componentes principais responsáveis pelos efeitos terapêuticos. Além disso, abrange compostos e metabólitos relevantes tanto para a indústria farmacêutica quanto veterinária, fornecendo referências para a medição e análise precisa dessas substâncias. Padrões de controle de nitrosaminas são cruciais para detectar e mitigar nitrosaminas potencialmente prejudiciais em formulações de medicamentos. Padrões de toxicologia ajudam a avaliar a segurança e os potenciais efeitos adversos de compostos farmacêuticos. Além disso, padrões de ativadores e inibidores de enzimas são vitais para pesquisa e desenvolvimento, permitindo estudos precisos de vias bioquímicas e mecanismos de ação de medicamentos. Esses padrões farmacêuticos são ferramentas indispensáveis para conformidade regulatória, controle de qualidade e pesquisa, garantindo que os produtos farmacêuticos atendam a rigorosos critérios de segurança e eficácia.
Subcategorias de "Padrões Farmacêuticas"
- APIs para pesquisa e impurezas(273.486 produtos)
- Activadores e Inibidores de Enzimas(2.827 produtos)
- Nitrosaminas(2.606 produtos)
- Compostos e metabolitos farmacêuticos e veterinários(2.602 produtos)
- Toxicologia(13.652 produtos)
Foram encontrados 7836 produtos de "Padrões Farmacêuticas"
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(2R,3S)-N-Benzoyl-3-phenyl Isoserine Methyl Ester
CAS:Produto Controlado<p>Applications (2R,3S)-N-Benzoyl-3-phenyl Isoserine Methyl Ester is an intermediate in the preparation of potent anticancer drug Paclitaxel (P132500) used to study the location of the binding sites.<br>References Paal, K. et al.: Bioorg. Med. Chem., 15, 1323 (2007); Krawczyk, E. et al.: J. Pharm. Pharmacol., 57, 791 (2005);<br></p>Fórmula:C17H17NO4Cor e Forma:Off White PowderPeso molecular:299.32DL-Indole-3-lactic Acid Methyl Ester-D5
CAS:Produto Controlado<p>Applications DL-Indole-3-lactic Acid Methyl Ester-D5 is an intermediate used in the synthesis of DL-Indole-3-lactic Acid-d5 (I627102), which is the isotope labelled analog of DL-Indole-3-lactic Acid (I627100); a reagent in the synthesis of 2-hydroxy-1-(1H-indol-3-yl)-4-methylpentan-3-one which has weak antibacterial activity against 16 bacterial strains, including Escherichia coli, Bacillus subtilis and Staphylococcus aureus. DL-Indole-3-lactic Acid is also used in the preparation of Monatin, a natural sweet peptidomimetic.<br>References Nguyen, S.T., et al.: Bioorg. Med. Chem. Lett., 20, 5739 (2010); Nakamura, K., et al.: Peptide Sci., 40, 61 (2003)<br></p>Fórmula:C12D5H8NO3Cor e Forma:NeatPeso molecular:224.267Oxindole-3-acetic Acid-d4
CAS:Produto ControladoFórmula:C10D4H5NO3Cor e Forma:NeatPeso molecular:195.208N-Demethyl Mifepristone
CAS:<p>Applications A metabolite of Mifepristone (M343975).<br>References Ringler, I., et al.: Metabolism, 13, 37 (1964), Gagne, D., et al.: J. Steroid. Biochem., 25, 315 (1986), Jang, G., et al.: Biochem. Pharmacol., 52, 753 (1996), Hild, S., et al.: Hum. Reprod., 15, 822 (2000), Gainer, E., et al.: Steroids, 68, 1005 (2003),<br></p>Fórmula:C28H33NO2Cor e Forma:NeatPeso molecular:415.57(+)-(S)-Dihydrokavain
CAS:Produto Controlado<p>Applications (+)-(S)-Dihydrokavain is a kavalactone found in kava beverages consumed by South Pacific islanders. Furthermore, roots and extracts of the kava plant have been used in herbal medicine to treat sleep disturbances, as well as stress and anxiety.<br>References Warburton, E., et al.: Eur. J. Mass Spectrom., 12, 223(2006); Wang, J., et al.: J. Food Sci. Technol., 52, 1164 (2015)<br></p>Fórmula:C14H16O3Cor e Forma:NeatPeso molecular:232.283-Nitropyridine
CAS:Produto Controlado<p>Applications Used in the novel synthesis of biologically active nitro heterocyclic compounds.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Pawar, N., et al.: Eur. J. Pharm. Sci., 21, 115 (2004), Badgujar, D., et al.: J. Sci. Ind. Res., 66, 250 (2007),<br></p>Fórmula:C5H4N2O2Cor e Forma:NeatPeso molecular:124.108-Amino-7-oxopelargonic Acid Hydrochloride
CAS:Produto Controlado<p>Applications An intermediate in the synthesis of biotin. Pimeloyl-CoA is transformed into AOP in the presence of L-alanine by the enzyme AOP synthase. The catalytic mechanism of AOP synthase has been studied for the elucidation of inhibitors as potential antimicrobial agents.<br>References Ohsugi, M., et al.: J. Nutr. Sci. Vitaminol., 34 (4), 343 (1985), Pearson, B.M., et al.: Lett. Appl. Microbiol., 10 (2), 89 (1990), Ploux, O., et al.: Biochem. J., 283, 327 (1992)<br></p>Fórmula:C9H17NO3·ClHCor e Forma:NeatPeso molecular:223.702-Naphthol-6,8-disulfonic Acid Potassium Salt
CAS:<p>Applications 2-Naphthol-6,8-disulfonic Acid Potassium Salt is a salt of 2-Naphthol-6,8-disulfonic Acid (N368023). 2-Naphthol-6,8-disulfonic acid is a useful research chemical for organic synthesis and other chemical processes. A reagent used in the preparation of food dyes with numerous applications.<br>References Baltac, T., et al.: Revista de Chimie, 63, 618 (2012)<br></p>Fórmula:C10H8O7S2•x(K)Cor e Forma:Off-WhitePeso molecular:304.30391b-Cembrenediol
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications β-Cembrenediol is an inhibitor of tumor promotion. Novel c-Met inhibitors which are used in anticancer treatments.<br>References Le-Huu, P. et al.: ChemCatChem., 8, 3755 (2016); Ebrahim, H. et al.: Bioorg. Med. Chem., 24, 5748 (2016);<br></p>Fórmula:C20H34O2Cor e Forma:Off-WhitePeso molecular:306.48Methyl(4-methylnaphthalen-1-ylmethyl)amine
CAS:Produto Controlado<p>Applications Methyl(4-methylnaphthalen-1-ylmethyl)amine is a reagent in the preparation of heterocyclic compounds as enoyl-acyl carrier protein reductase FabI inhibitors and antibacterial agents.<br>References Stuetz, A., et al.: J. Med. Chem., 29, 112 (1986); Berman, J., et al.: PCT Int. Appl., 2004:515512 (2004)<br></p>Fórmula:C13H15NCor e Forma:NeatPeso molecular:185.26Cinnamyl Alcohol
CAS:Produto Controlado<p>Stability Light Sensitive<br>Applications Cinnamyl alcohol is used as a fragrance ingredient and is a known a cause of allergic dermatitis in humans. Cinnamyl alcohol is also part of a group of cinnamic acid derivatives (for example: 4-Methoxycinnamic acid -M262150) that might be useful for the treatment of diabetes and obesity.<br>References Adisakwattana, S., et al.: J. Emzym. Inhib., 28, 1067, (2013); Basketter, D.: Acta-Derm.-Venereol., 72, 264 (1992); Letizia, C. S., et al.: Food Chem. Toxicol., 43, 837 (2005);<br></p>Fórmula:C9H10OCor e Forma:Light YellowPeso molecular:134.18(5α)-Androst-2-en-17-one, 90%
CAS:Produto Controlado<p>Applications Metabolite of 5α-Androst-16-en-3β-ol<br>References Gower, D., et al.: J. Steroid Biochem. Mol. Biol., 63, 81 (1997), Zorko, M., et al.: Steroids, 65, 46 (2000), Diel, P., et al.: Toxicol. Lett., 169, 64 (2007),<br></p>Fórmula:C19H28OPureza:90%Cor e Forma:NeatPeso molecular:272.423,3-Bis(2-hydroxyethyl)urea
CAS:Produto Controlado<p>Applications 3,3-bis(2-hydroxyethyl)urea (cas# 23270-55-5) is a useful research chemical.<br></p>Fórmula:C5H12N2O3Cor e Forma:NeatPeso molecular:148.16Isovaleric Acid Ethyl-d5 Ester
CAS:Produto Controlado<p>Applications Isovaleric Acid Ethyl-d5 Ester is the labeled analogue of Isovaleric Acid Ethyl Ester (I917575), an odorant found in soy sauce.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Feng, Y., et. al.: Food Chem., 167, 220 (2015)<br></p>Fórmula:C7H9D5O2Cor e Forma:NeatPeso molecular:135.225-Oxo Rosuvastatin
CAS:Produto Controlado<p>Impurity Rosuvastatin EP Impurity C (Calcium Salt)<br>Stability Hygroscopic<br>Applications 5-Oxo Rosuvastatin (Rosuvastatin EP Impurity C (Calcium Salt)) is a Rosuvastatin (R700500) impurity.<br>References Endo, A., et al.: J. Antibiot., 32, 852 (1979), Beck, G., et al.: J. Med. Chem., 33, 52 (1990), Koga, T., et al.: Lipids, 30, 775 (1995),<br></p>Fórmula:C22H26FN3O6SCor e Forma:Light Yellow To Dark BeigePeso molecular:479.529,10-Dibromoanthracene-2-sulfonic Acid Sodium Salt
CAS:Produto Controlado<p>Applications 9,10-Dibromoanthracene-2-sulfonic Acid Sodium Salt (cas# 87796-18-7) is a compound useful in organic synthesis.<br></p>Fórmula:C14H7Br2O3S·NaCor e Forma:NeatPeso molecular:438.07Hydrocinnamic Acid
CAS:<p>Applications Used in the compositions for the treatment of blood disorders using α-methylhydrocinnamic acid.<br>References Migliaccio, A., et al.: Blood, 76, 1150 (1990), McDonagh, K., et al.: J. Biol. Chem., 266, 11965 (1991),<br></p>Fórmula:C9H10O2Cor e Forma:WhitePeso molecular:150.171,5-Diisocyanatonaphthalene
CAS:Produto Controlado<p>Applications 1,5-DIISOCYANATONAPHTHALENE (cas# 3173-72-6) is a useful research chemical.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br></p>Fórmula:C12H6N2O2Cor e Forma:White To Off-WhitePeso molecular:210.19Diphenhydramine N-Oxide
CAS:<p>Stability Hygroscopic<br>Applications A metabolite of Diphenhydramine (D486900) in humans.<br>References Breyer-Pfaff, U., et al.: Drug Metab. Dispos., 25, 340 (1997),<br></p>Fórmula:C17H21NO2Cor e Forma:NeatPeso molecular:271.35Celecoxib Carboxylic Acid
CAS:Produto ControladoFórmula:C17H12F3N3O4SCor e Forma:Off WhitePeso molecular:411.36Methyl-1-naphthalenemethylamine
CAS:<p>Impurity Terbinafine EP Impurity A; Terbinafine BP Impurity A; Terbinafine USP Related Compound A<br>Applications Terbinafine EP Impurity A. Terbinafine BP Impurity A. Terbinafine USP Related Compound A<br></p>Fórmula:C12H13NCor e Forma:OrangePeso molecular:171.249-Chloro Triamcinolone Acetonide
CAS:<p>Applications Triamcinolone Acetonide (T767165) impurity.<br>References Laurent, H., et al.: J. Steroid Biochem., 6, 185 (1975),<br></p>Fórmula:C24H31ClO6Cor e Forma:WhitePeso molecular:450.9517β-Dihydro Equilin 3-Sulfate Sodium Salt
CAS:<p>Stability Hygroscopic<br>Applications A metabolite of Equilin (E592800).<br>References Enmark, E., et al.: J. Clin. Endocrinol. Metab., 82, 4258 (1997), Wang, Z., et al.: J. Med. Chem., 43, 2419 (2000), Jiang, X., et al.: Steroids, 71, 334 (2006),<br></p>Fórmula:C18H21O5S·NaCor e Forma:NeatPeso molecular:372.414-Hydroxy Atorvastatin Disodium Salt
CAS:<p>Applications A metabolite of Atorvastatin, a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.<br>References Smith, S., et al.: Am. J. Cardiol., 80, 10H (1997), Jacobsen, W., et al.: Drug Metab. Dispos., 28, 1369 (2000), Istvan, E., et al.: Science, 292, 1160 (2001), Tabernero, L., et al.: J. Biol. Chem., 278, 19933 (2003), Bratton, L., et al.: Bioorg. Med. Chem., 15, 5576 (2007),<br></p>Fórmula:C33H33FN2Na2O6Cor e Forma:White To BrownPeso molecular:618.602,5-Dichloro-4-nitrophenol
CAS:Produto Controlado<p>Applications 2,5-DICHLORO-4-NITROPHENOL (cas# 5847-57-4) is a useful research chemical.<br></p>Fórmula:C6H3NO3Cl2Cor e Forma:NeatPeso molecular:207.99Pipamazine
CAS:<p>Applications Pipamazine is a drug od the phenothiazine class which used to be used as an antiemetic.<br>References Bhargava, K. et al.: Br. J. Pharmacol. Chemother., 22, 154 (1964); Bhargava, K. et al.: Br. J. Pharmacol. Chemother., 21, 436 (1963);<br></p>Fórmula:C21H24ClN3OSCor e Forma:NeatPeso molecular:401.955’-Deoxyfluorouridine-13C,15N2
CAS:Produto Controlado<p>Applications 5’-Deoxyfluorouridine-13C,15N2 is a compound useful in organic synthesis.<br></p>Fórmula:C8CH11FN2O5Cor e Forma:NeatPeso molecular:249.174’-Hydroxy Nimesulide
CAS:Produto Controlado<p>Applications The main metabolite of Nimesulide (N477500).<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Facino, R.M., et al.: Drugs, 46 (Suppl1),15 (1993), Westphal, J., et al.: J. Antimicrob. Chemother., 33, 387 (1994), Castell, J., et al.: Cell Biol. Toxicol., 13, 331 (1997), Georges, H., et al.: Life Sci., 65, 151 (1999), Singla, A.K., et al.: J. Pharm. Pharmacol., 52, 467 (2000),<br></p>Fórmula:C13H12N2O6SCor e Forma:White To Light BrownPeso molecular:324.314-(4-Oxobutyl)benzoic Acid Methyl Ester
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 4-(4-Oxobutyl)benzoic Acid Methyl Ester is used as a reagent in the preparation of Pemetrexed (P219500) and furoxanoxyalkyl esters of Pemetrexed as antifolates and nitric oxide donors for use as anticancer agents.<br>References Zhao, D., et al.: Zhongguo Yaowu Huaxue Zazhi, 18, 445 (2008); Yi, B., et al.: Zhongguo Yiyao Gongye Zazhi, 37, 798 (2006); Min, T., et al.: Med. Chem. Res., 18, 495 (2009)<br></p>Fórmula:C12H14O3Cor e Forma:NeatPeso molecular:206.24Acetyldiethylstilbestrol 2,3,4-Tri-O-acetyl-β-D-glucuronide Methyl Ester
CAS:Produto Controlado<p>Applications Intermediate for the preparation of Diethylstilbestrol β-D-Glucuronide.<br></p>Fórmula:C33H38O12Cor e Forma:Light YellowPeso molecular:626.652,4-Difluoro-α-(1H-1,2,4-triazolyl)acetophenone
CAS:Produto Controlado<p>Impurity Voriconazole EP Impurity A; Voriconazole USP Related Compound C<br>Applications 2,4-Difluoro-α-(1H-1,2,4-triazolyl)acetophenone (Voriconazole EP Impurity A; Voriconazole USP Related Compound C) is an antifungal activity, particularly toward Candida albicans and Candida parapsilosis<br>References Upadhayaya, R., et al.: Eur. J. Med. Chem., 39, 579 (2004), Sheng, C., et al.: J. Med. Chem., 49, 2512 (2006),<br></p>Fórmula:C10H7F2N3OCor e Forma:BeigePeso molecular:223.181,2-Benzenedicarboxylic Acid Di-C6,8,10-alkyl Esters (1:1:1 Mixture of D446490 and D481750 and D4393
CAS:Produto Controlado<p>Applications 1,2-Benzenedicarboxylic Acid Di-C6,8,10-alkyl Esters_x000D_(1:1:1 Mixture of D446490 and D481750 and D439395, by weight) (cas# 68515-51-5) is a compound useful in organic synthesis.<br></p>Fórmula:C11H9D3O4Cor e Forma:ColourlessPeso molecular:304.38Diacetyl Bis(2,4-dinitrophenylhydrazone)
CAS:Produto Controlado<p>Applications 2,4-Dinitrophenylhydrazone (DNPH) derivative.<br>References Lindsay, R.C., et al.: J. Food Sci., 29, 266 (1964),<br></p>Fórmula:C16H14N8O8Cor e Forma:NeatPeso molecular:446.336-Hydroxy-2-naphthalenesulfonic Acid Sodium Salt
CAS:Produto Controlado<p>Applications 6-Hydroxy-2-naphthalenesulfonic Acid Sodium Salt is a coupling component used to prepare heterocyclic monoazo dyes.<br>References Naik, D., et al., Dyes and Pigments., 14,1 (1990); Bilimoria, J., et al.: Colourage, 57, 72 (2010)<br></p>Fórmula:C10H7O4S·NaCor e Forma:White To Off-WhitePeso molecular:246.22Dihydro Ferulic Acid
CAS:Produto Controlado<p>Applications A caffeine metabolite which showed high antioxidant activity. It is a very sensitive biomarker for the consumption of relatively small amount of coffee.<br>References Buchanan, C., et al.: J. Sci. Food Agric., 71, 459 (1996), Andreasen, M., et al.: J. Agric. Food Chem., 49, 5679 (2001), Poquet, L., et al.: Drug Metab. Dispos., 36, 190 (2008),<br></p>Fórmula:C10H12O4Cor e Forma:NeatPeso molecular:196.20Succinyl Carnitine Chloride Salt
CAS:Produto Controlado<p>Stability Very Very Hygroscopic<br>Applications A metabolic intermediate of L-Carnitine.<br>References Huffman, K. et al.: Diab. Care, 32, 1678 (2009);<br></p>Fórmula:C11H20NO6ClCor e Forma:NeatPeso molecular:297.73Propoxyphenyl-thiohydroxyhomosildenafil
CAS:Produto Controlado<p>Applications Propoxyphenyl-thiohydroxyhomosildenafil is an analogue of Hydroxythiohomo Sildenafil (H963150).<br>References Balayssac, S., et. al.: J. Pharmaceut. Biomed., 63, 135 (2012)<br></p>Fórmula:C24H34N6O4S2Cor e Forma:NeatPeso molecular:534.69Pyruvic Acid-2-13C Sodium Salt
CAS:Produto Controlado<p>Applications Labelled Pyruvic acid (P998900). Intermediate in sugar metabolism and in enzymatic carbohydrate degradation (alcoholic fermentation) where it is converted to acetaldehyde and CO2 by carboxylase. In muscle, Pyruvic acid (derived from glycogen) is reduced to lactic acid during exertion, which is reoxidized and partially retransformed to glycogen during rest. The liver can convert Pyruvic acid to alanine by amination. A diagnostic agent for Parkinson disease.<br>References Wenzel, A., et al.: J. Neurosci., 21, 53 (2001), Martinez., et al.: Development, 6, 851 (2002), Nakayama, K., et al.: J. Biochem., 146, 757 (2009), Tanaka, T., et al.: J. Pharmacol. Sci., 109, 24 (2009),<br></p>Fórmula:C213CH3NaO3Cor e Forma:NeatPeso molecular:111.042-Phenylbutyrylurea
CAS:<p>Applications 2-Phenylbutyrylurea is used in the synthesis and discovery of novel trypanosomicidal drug-like compounds which is useful in the treatment of diseases. A degradation product of Phenobarbitol (P316760).<br>References Castillo-Garit, J. et al.; Eur. J. Med. Chem., 46, 3324 (2011);<br></p>Fórmula:C11H14N2O2Cor e Forma:NeatPeso molecular:206.24trans-Linalool Oxide
CAS:<p>Applications trans-Linalool Oxide is a derivative of Linalool (L465950), which is a terpene alcohol common in various flowers and spice plants. trans-Linalool Oxide is also an isomer of cis-Linalool Oxide, which has been employed to assess the effect of vine on the glycosylated flavour procurers in grapes.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Baratta, M. T., et al.: J Essent Oil Res 10, 618 (1998); Bureau, S. M., et al.: J. Agric. Food Chem. 48, 1290 (2000)<br></p>Fórmula:C10H18O2Cor e Forma:NeatPeso molecular:170.252-Isopropylnaphthalene
CAS:Produto Controlado<p>Applications 2-Isopropylnaphthalene has been seen to likely act as CYP2F2 substrates through molecular modelling of the mouse cytochrome P450 CYP2F2.<br>References Lewis, D.F.V., et. al.: Drug Metab. and Drug Interact., 19, 97 (2002)<br></p>Fórmula:C13H14Cor e Forma:NeatPeso molecular:170.255-Bromoacenaphthene
CAS:Produto Controlado<p>Applications 5-Bromoacenaphthene<br></p>Fórmula:C12H9BrCor e Forma:NeatPeso molecular:233.1Dodecanedioic-d20 Acid
CAS:Produto Controlado<p>Applications Dodecanedioic-d20 Acid is labelled Dodecanedioic Acid (D494530) which induces mutation of dodecanedioic acid producing Candida tropicalis.<br>References Ardawi, M., et al.: Biochem. J., 212, 835 (1983); Renner, F., et al.: J. Lipid Res., 27, 72 (1986); Gu, H., et al.: Anal. Chem., 79, 89 (2007)<br></p>Fórmula:C12D20H2O4Cor e Forma:NeatPeso molecular:250.425’-Tosyl Adenosine
CAS:Produto Controlado<p>Applications 5’-Tosyl Adenosine (cas# 5135-30-8) is a compound useful in organic synthesis.<br></p>Fórmula:C17H19N5O6SCor e Forma:NeatPeso molecular:421.43dl Homocysteine Thiolactone Hydrochloride
CAS:<p>Applications dl Homocysteine Thiolactone Hydrochloride (cas# 6038-19-3) is a compound useful in organic synthesis.<br>Chemical Name: dl Homocysteine Thiolactone Hydrochloride (cas# 6038-19-3) is a compound useful in organic synthesis.<br></p>Fórmula:C4H7NOS·ClHCor e Forma:NeatPeso molecular:153.633,7,4'-Trihydroxyflavone
CAS:Produto Controlado<p>Stability Hygroscopic<br>Applications 3,7,4'-Trihydroxyflavone (cas# 2034-65-3) is a useful research chemical.<br></p>Fórmula:C15H10O5Cor e Forma:NeatPeso molecular:270.241-Phenyl-1,2,3,4-tetrahydronaphthalene
CAS:<p>Applications 1-phenyl-1,2,3,4-tetrahydronaphthalene (cas# 3018-20-0) is a useful research chemical.<br></p>Fórmula:C16H16Cor e Forma:ColourlessPeso molecular:208.2981-(2-Nitroethyl)-2-naphthol
CAS:Produto Controlado<p>Applications 1-(2-Nitroethyl)-2-naphthol is an aromatic alcohol that is used in photoacid for extremely long lived and reversible pH jumps.<br>References Nunes, R.M.D., et al.: J. Am. Chem. Soc., 131, 26 (2009);<br></p>Fórmula:C12H11NO3Cor e Forma:NeatPeso molecular:217.22
